Salbutamol-Teva aerosol 100 µg/dose 200 doses 12 ml
A country
Ireland
Country of manufacture may vary depending on the batch of goods. Please check with the operator for detailed information when confirming your order.
Active substance
Salbutamol
Compound
Cylinder 200 doses
of Salbutamol sulfate 124 mcg per 1 dose. Excipients: hydrofluoroalkane (HFA-134a) - 26.46 mg, ethanol - 3.42 mg. A dosed aerosol for inhalation, when sprayed onto glass it forms a white spot.
pharmachologic effect
Salbutamol is a selective β2-adrenergic receptor antagonist. In therapeutic doses, it acts on β2-adrenergic receptors of the smooth muscles of the bronchi, providing a pronounced bronchodilator effect, prevents and relieves bronchospasm, and increases the vital capacity of the lungs. Prevents the release of histamine, a slow-reacting substance from mast cells and neutrophil chemotaxis factors. Causes a slight positive chrono- and inotropic effect, dilates the coronary arteries and practically does not reduce blood pressure. It has a tocolytic effect: it reduces the tone and contractile activity of the myometrium. It has a number of metabolic effects: it reduces the K+ content in plasma, affects glycogenolysis and insulin secretion, has a hyperglycemic (especially in patients with bronchial asthma) and lipolytic effect, and increases the risk of developing acidosis. The effect of the drug begins 5 minutes after inhalation administration and lasts for 4-6 hours.
Indications for use
- prevention and relief of bronchospasm in bronchial asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis, emphysema.
Side effects
Salamol Eco may cause finger tremor, which is a typical side effect of all β2-adrenergic agonists. Headache, dizziness, increased excitability, anxiety, sleep disturbance, insomnia, dilation of peripheral blood vessels (facial skin flushing), a slight compensatory increase in heart rate, increased blood pressure, chest pain, and arthralgia may occur. Hypersensitivity reactions may develop (including angioedema, urticaria, erythema, nasal congestion, bronchospasm, hypotension and collapse); muscle cramps, nausea, vomiting, dyspepsia. Inhaled drugs can cause paradoxical bronchospasm. Inhaled drugs can cause irritation of the mucous membrane of the mouth and pharynx (pharyngitis), and cough. Salbutamol therapy may cause hypokalemia, which can be serious for the patient, as well as reversible metabolic disorders, such as increased blood glucose concentrations. The drug may cause agitation and increased motor activity in children. Arrhythmias (including atrial fibrillation, supraventricular tachycardia and extrasystole) may occur.
Contraindications
— rhythm disturbances (paroxysmal tachycardia, polytopic ventricular extrasystole);
- myocarditis; - heart defects; - aortic stenosis; - cardiac ischemia; - tachyarrhythmia; - thyrotoxicosis; — decompensated diabetes mellitus; - glaucoma; - epileptic seizures; - pyloroduodenal narrowing; - renal or liver failure; - simultaneous use of non-selective beta-blockers; - pregnancy; - children under 2 years of age; - hypersensitivity to any component of the drug. Use during pregnancy and breastfeeding Contraindicated during pregnancy. During lactation it is prescribed only in cases where the expected benefit to the mother exceeds any possible risk to the child.
Use in children Children from 2 to 12 years of age: in the event of an attack of bronchial asthma, as well as to prevent attacks of bronchial asthma associated with exposure to an allergen or caused by physical activity, the recommended dose is 100-200 mcg (1 or 2 inhalations).
Mode of application
Adults and children over 12 years of age: 100-200 mcg (1-2 inhalation doses) to relieve asthma attacks. To control the course of asthma of mild severity - 1-2 doses 1-4 times / day and moderate severity of the disease - in the same dosage in combination with other anti-asthmatic drugs. To prevent asthma from physical exertion - 20-30 minutes before exercise, 1-2 doses per dose. Children from 2 to 12 years: with the development of an attack of bronchial asthma, as well as to prevent attacks of bronchial asthma associated with exposure to an allergen or caused by physical activity, the recommended dose is 100-200 mcg (1 or 2 inhalations). The daily dose should not exceed 800 mcg (8 inhalations). Instructions for using the inhaler Check the operation of the inhaler before using it for the first time, and also if you have not used it for some time. 1. Remove the cap from the inhaler. Make sure there is no dust or dirt in the outlet tube. 2. Hold the balloon in an upright position with your thumb on the bottom and your index finger on the top of the balloon. 3. Shake the can vigorously up and down. 4. Exhale as deeply as possible (without straining). Pinch the outlet tube of the can tightly with your lips. 5. Take slow, deep breaths. As you inhale, press your index finger on the valve of the canister, releasing a dose of medication. Continue to inhale slowly. 6. Remove the inhaler tube from your mouth and hold your breath for 10 seconds or as long as you can without straining. Exhale slowly. If more than one dose of medication is needed, wait about a minute and then repeat from step 2. Replace the cap on the inhaler. Take your time when performing steps 3 and 4. When releasing a dose of medication, it is important to inhale as slowly as possible. First, practice in front of a mirror. If you notice steam coming out of the top of the canister or from the corners of your mouth, start again from step 2. Cleaning your inhaler The inhaler should be cleaned at least once a week. Remove the metal can from the plastic case and rinse the case and cap with warm water. Do not use hot water. Dry thoroughly, but do not use heating devices. Place the canister back into the case and put on the cap. Do not immerse the metal canister in water.
special instructions
In patients with severe or unstable asthma, the use of bronchodilators should not be the main or only method of therapy. If the effect of the usual dose of Salamol Eco becomes less effective or shorter lasting (the effect of the drug should last for at least 3 hours), the patient should consult a doctor. Frequent use of salbutamol can lead to increased bronchospasm and sudden death, and therefore it is necessary to take breaks of several hours between doses of the drug. An increased need for the use of inhaled β2-adrenergic agonists with a short duration of action to control the symptoms of bronchial asthma indicates an exacerbation of the disease. In such cases, the patient's treatment plan should be reviewed and the issue of prescribing or increasing the dose of inhaled or systemic corticosteroids should be decided. Therapy with β2-adrenergic agonists may lead to hypokalemia. Particular caution is recommended when treating severe attacks of bronchial asthma, since in these cases hypokalemia may increase as a result of the simultaneous use of xanthine derivatives, corticosteroids, diuretics, as well as due to hypoxia. In such situations, it is necessary to monitor the level of potassium in the blood serum. The container with Salamol Eco cannot be pierced, disassembled or thrown into fire, even if it is empty. Like most other inhalation products in aerosol packages, Salamol Eco may be less effective at low temperatures. When cooling the cylinder, it is recommended to remove it from the plastic case and warm it with your hands for a few minutes.
Overdose
Symptoms: nausea, vomiting, increased excitability, hallucinations, tachycardia, ventricular flutter, peripheral vasodilatation, decreased blood pressure, hypoxia, acidosis, hypokalemia, hyperglycemia, muscle tremors, headache. Treatment: - drug withdrawal, cardioselective beta-blockers; - symptomatic therapy. If overdose is suspected, serum potassium levels should be monitored.
Interaction with other drugs
Theophylline and other xanthines, when used simultaneously with salbutamol, increase the likelihood of developing tachyarrhythmias; agents for inhalation anesthesia, levodopa - severe ventricular arrhythmias. It is not recommended to use Salamol Eco and non-selective beta-adrenergic receptor blockers, such as propranolol, at the same time. MAO inhibitors and tricyclic antidepressants enhance the effect of salbutamol and can lead to a sharp decrease in blood pressure. Salbutamol enhances the effect of central nervous system stimulants, the side effects of thyroid hormones, cardiac glycosides. Reduces the effectiveness of antihypertensive drugs and nitrates. Hypokalemia may increase as a result of the simultaneous use of xanthine derivatives, corticosteroids, and diuretics. Simultaneous administration with anticholinergic drugs (including inhaled ones) may increase intraocular pressure.
Dispensing conditions in pharmacies
On prescription
Directions for use and doses
Inhalation.
To relieve bronchospasm: 100 mcg (1 inhalation) 1–4 times a day. If necessary, the dose can be increased to 200 mcg (2 inhalations) 1–4 times a day.
For the prevention of bronchospasm: 100–200 mcg (1–2 inhalations) 15–30 minutes before physical activity or possible exposure to an allergen.
The maximum daily dose should not exceed 800 mcg (8 inhalations) per day.
At least 4 hours should pass between each dose taken.
Patient instructions for using the inhalation device
Before using the inhalation device for the first time or if it has not been used for some time, it is necessary to check its functionality by pressing the valve of the canister and releasing a dose of medication into the air.
1. Remove the protective cap from the inhalation device and make sure that the outlet tube of the inhalation device is clean. Hold the inhalation device between the index finger and thumb in a vertical position, with the thumb placed on the bottom of the inhalation device and the index finger on the metering valve of the aluminum cylinder.
2. Shake the aluminum can vigorously up and down.
3. Exhale deeply through your mouth. Press the outlet tube of the inhalation device tightly with your lips.
4. Take a slow and deep breath. At the moment of inhalation, press the dosing valve of the cylinder with your index finger, releasing the dose of Salbutamol-Teva, and continue to inhale slowly.
5. Remove the inhalation device from the mouth and hold your breath for 10 seconds or for as long as does not cause discomfort. Exhale slowly.
6. After inhalation, rinse your mouth with water, trying not to swallow the aerosol that got onto the oral mucosa during inhalation.
7. If you need to administer more than one dose of the drug, wait 1 minute and repeat all steps from step 2 to step 6.
8. Close the inhalation device with the protective cap.
There is no need to rush through steps 3 and 4. When releasing a dose of medication, it is important to inhale as slowly as possible. Before use, you can practice in front of a mirror. If you notice "steam" coming from the top of the can or from the corners of your mouth, you should start again from step 2.
Cleaning the inhaler. The inhalation device should be cleaned at least once a week. Remove the aluminum cylinder from the inhalation device. Gently rinse the inhalation device and protective cap with warm water. Do not use hot water! Shake the inhalation device and protective cap to remove any remaining water and dry them without using heating devices.
Do not allow the aluminum cylinder to come into contact with water!
