Compound
benzydamine hydrochloride as an active substance , as well as the following additional components: sodium chloride, trimethylacetylammonium-p-toluenesulfonate, povidone.
The vaginal solution contains benzydamine hydrochloride , as well as the following additional components: ethyl alcohol 96, purified water, trimethylacetylammonium para-toluene sulfonate, polysorbate 20, rose oil.
Side effects
Cases of adverse reactions during treatment or prevention are quite rare. They manifest themselves mainly as local allergic symptoms: rashes, redness of the mucous membranes, their swelling, itching.
Using the solution for too long can cause a feeling of dry mouth, as the active substance penetrates into the bloodstream. You should stop treatment and consult your supervising physician. He will replace Tantum Rosa with its current analogue and prescribe medications to eliminate all signs of an allergic reaction. Some side effects are reversible and disappear after reducing dosages.
Pharmacodynamics and pharmacokinetics
The medicine belongs to the group of indazoles . This is a remedy that has anti-inflammatory, decongestant, antibacterial, antiseptic, antifungal and analgesic effects.
The active substance of the drug stabilizes cell membranes and inhibits the synthesis of prostaglandins . It also helps restore the integrity of the vaginal epithelium and contributes to its resistance to pathogenic effects .
The antibacterial effect is due to the rapid penetration of microorganisms through the outer membranes, destruction of their cellular structures and disruption of metabolic processes .
When used topically, it is well absorbed through the mucous membranes and penetrates into inflamed tissues. It is excreted primarily through the kidneys and intestines in the form of conjugation products or metabolites .
Pharmacological properties
Benzidamine is an NSAID with analgesic and anti-exudative effects. When applied topically, benzydamine also has an antiseptic and local anesthetic effect. Using a spectrofluorimeter, it was established that benzydamine adheres to the vaginal epithelium and reaches a concentration of 9.7 ± 6.24 μg/g. gradual absorption causes a low concentration of the drug in the blood plasma, which is not enough for systemic pharmacological effects. excretion occurs primarily in urine in the form of inactive metabolites or conjugates.
Indications for use
The medicine is used for:
- inflammatory diseases of the cervix, vulva and vagina;
- after radiotherapy ;
- fungal and trichomonas infections ;
- the need to prevent infectious complications in postpartum women;
- the need to accelerate reparative processes after childbirth;
- postpartum infections ( vulvitis , vaginitis and vulvovaginitis , etc.);
- the need to prevent post- and preoperative complications in surgical gynecology;
- inflammatory processes in the area of the uterine pharynx.
In addition, Tantum Rose is used after chemotherapy for tumors.
Interaction
In gynecological practice, there have been no cases of interaction of benzydamine with the ingredients of local products. But doctors recommend maintaining a 20-minute interval between applying it and antiseptic drugs, regeneration stimulants, local antibiotics and antimycotics. If a doctor prescribes douching by other means, then the treatment procedure should be carried out an hour after irrigation with Tantum Rose. You cannot use drugs with it whose active composition is the same active substance.
Instructions for use Tantum Roses (Method and dosage)
The instructions for Tantum Rose indicate that douching takes place in a lying position. For a single procedure, use 140 ml. The liquid should remain in the vagina for several minutes.
For those who purchased Tantum Rose powder, the instructions for use indicate that the contents of the sachet should be dissolved in 500 ml of water. How to use the solution depends on the nature of the disease:
- for bacterial vaginosis, you need to use the medicine 1-2 times a day. The course is designed for 7-10 days;
- for the purpose of preventing post- and preoperative complications in surgical gynecology, as well as as a hygienic means after childbirth, douching is performed once a day. The course lasts 3-5 days;
- for vulvovaginitis and cervicovaginitis, the medicine is used 2 times a day. The course lasts 10 days.
The instructions do not indicate how to open the bottle. However, this point is difficult for many. Those who have already tried this product advise, first of all, to open the pink lid upwards, then pull the white pin all the way.
Recommendations
It is advisable to pre-test the drug. To do this, rub a little solution into the elbow bend. There is no hypersensitivity if the skin does not turn red or swell within 30-40 minutes.
If the solution gets into your eyes, rinse them with plenty of running water. Severe burning and redness of the conjunctiva requires consultation with a doctor.
During treatment you do not need to stop driving vehicles. It is also acceptable to perform work that requires special concentration and increased reaction speed.
It is advisable to avoid drinking alcohol. Ethyl alcohol upsets metabolic processes, which can negatively affect the speed of recovery.
Reviews of Tantum Rose
Reviews about Tantum Rose on the Internet can be found very contradictory. Someone was prescribed this drug by a doctor, and the medicine helped, while others did not even dare to use it because of the inconvenience of use. It is precisely because of the last factor that many women still try to buy analogues. Also, experts do not recommend using this remedy during pregnancy, but there are no direct contraindications to this.
In general, there are practically no categorical negative reviews about Tantum Rose, so this product is popular.
special instructions
Long-term treatment with topical medications may result in hypersensitivity symptoms. in this case, you should stop using the drug and carry out appropriate therapy. Before using the drug in case of vaginal bleeding and/or leucorrhoea, you should consult a doctor.
Use during pregnancy and lactation. There are no contraindications for use during this period.
Children. There is not enough experience with use in children.
Impact on the ability to drive vehicles and operate other mechanisms. Does not affect.
Price Tantum Roses, where to buy
The price of Tantum Rose solution is usually about 700 rubles. Although in some places you can find this product at a much lower cost.
The price of Tantum Roses in powder form is also much lower - approximately 330 rubles. However, when using it, you need to spend time preparing the solution. So many women still prefer to buy a ready-made douche, despite the fact that the price of Tantum Rose in this case is noticeably higher.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
ZdravCity
- Tantum Rose vaginal solution.
0.1% 140ml 5 pcs.Angelini Francesco RUR 1,073 order - Tantum Rose powder for vaginal preg solution. 500mg 10 pcsAngelini Francesco
450 rub. order
Pharmacy Dialogue
- Tantum Rose 140ml No.5Angelini Francesco SpA
RUB 1,119 order
- Tantum Rose sachets 0.5g No. 10Angelini Francesco SpA
RUR 442 order
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Note!
Description of the drug Tantum Rosa gran. d/vaginal. solution 500 mg sachet No. 10 on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
Tantum Rose external solution 0.1% syringe bottle 140ml No. 5
Compound
Active substance: benzydamine hydrochloride - 0.1 g. Excipients: benzalkonium chloride, disodium edetate, ethanol 96%, polysorbate 20, rose oil, purified water.
Pharmacokinetics
When applied topically, the drug is well absorbed through the mucous membranes and penetrates into inflamed tissues.
Benzydamine is excreted mainly by the kidneys and through the intestines in the form of metabolites or conjugation products.
Indications for use
- in the postpartum period as a therapeutic and prophylactic agent for the prevention of postpartum infectious complications;
- specific vulvovaginitis (as part of complex therapy);
- nonspecific vulvovaginitis and cervicovaginitis of any etiology, including those secondary to chemotherapy and radiotherapy;
- bacterial vaginosis;
- prevention of postoperative infectious complications in surgical gynecology.
Contraindications
Hypersensitivity to any of the components of the drug.
Directions for use and doses
The drug is used intravaginally.
Vaginal solution 0.1% in a bottle, which is a disposable syringe, ready for use. The contents of the bottle must be heated in a water bath to body temperature. The procedure should be performed lying down, the liquid should remain in the vagina for several minutes. For one-time douching, use the entire volume of the bottle 140 ml.
In the postpartum period
as a therapeutic and prophylactic agent to accelerate the rehabilitation process and prevent postpartum infectious complications: the drug is used 1 time per day for 3-5 days.
For bacterial vaginosis
vaginal irrigation is carried out 1-2 times a day for 7-10 days.
For nonspecific vulvovaginitis and cervicovaginitis
of any etiology, including those secondary to chemotherapy and radiotherapy, the drug is used 2 times a day for at least 10 days.
For specific vulvovaginitis
(as part of complex therapy) the drug is used 2 times a day for 3-5 days.
For the prevention of postoperative infectious complications
in operative gynecology, the drug is used 1 time/day for 3-5 days.
Storage conditions
The drug should be stored out of the reach of children, protected from light at a temperature not exceeding 25°C.
Best before date
4 years. Do not use after the stated expiration date.
special instructions
Long-term use of the drug may lead to hypersensitivity.
When using the drug for long periods, consult a doctor.
Description
NSAIDs for topical use in gynecology.
Dosage form
Vaginal solution 0.1% is colorless, transparent, with a characteristic scent of roses.
Pharmacodynamics
NSAIDs for topical use, belongs to the indazoles group. It has anti-inflammatory and local analgesic effects, has antibacterial, antifungal and antiseptic effects.
The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis.
Benzidamine has an antibacterial effect due to rapid penetration through the membranes of microorganisms with subsequent damage to cellular structures, disruption of metabolic processes and cell lysis.
Has antifungal effect against Candida albicans. Causes structural modifications of the cell wall of fungi and the metabolic chains of mycetes and thus prevents their reproduction.
Side effects
In rare cases, allergic reactions and dryness of the oral mucosa are possible.
Use during pregnancy and breastfeeding
There are no contraindications to the topical use of Tantum® Rose during pregnancy and lactation (breastfeeding).
Interaction
No clinically significant interaction of the drug Tantum® Rose with other drugs has been established.
Overdose
Currently, no cases of overdose of Tantum® Rose have been reported.
Impact on the ability to drive vehicles and operate machinery
The use of the drug does not affect the ability to drive vehicles or engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
