Curantil n 25 tablet p/o film 25mg 120 pcs

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Dragee Curantil is usually classified as a blood thinner. It has a fairly gentle effect on the body, so it is ideal for use over a long period. Quite often, the drug is prescribed to pregnant women to avoid the development of thrombosis if a disease such as varicose veins has been diagnosed. However, prescribing medication is not always advisable. And therefore, sometimes doctors are forced to prescribe analogues of Curantil to their patients.

pharmachologic effect

Manufacturer: Berlin-Chemie, Germany
Release form: tablets, dragees

Active ingredient: dipyridamole 25 and 75 mg

Synonyms: Dipyridamole, Pencelin, Dipyridamole-FPO

Curantil is a drug from the group of antiplatelet agents. The action is based on the following pharmacological effects of the active substance:

• antiplatelet;
• vasodilator;
• hypotensive;
• nootropic;
• anti-adhesive;
• improving the supply of oxygen to the myocardium;
• activation of blood flow in the heart.

Metabolism of Dipyridamole (as part of Curantil 25 mg and its analogues) occurs in the liver, excretion in the bile.

Agrenox

How to replace sugar for type 2 diabetes

To replace the drug Curantil, the patient can use another cheap analogue - Agrenox. This drug is used for the prevention and treatment of transient ischemic disease and attacks of ischemic stroke. The medicine is available in the form of tablets with the active ingredient dipyridamole. 1 package usually contains from 30 to 60 tablets. The drug can be used only after being prescribed by a doctor.

What side effects might there be?

Before replacing Curantil with other medications, you must carefully study the instructions for each of them. Reviews from many patients indicate that if you neglect these rules and self-medicate, the cheap analogue Agrenox, like Curantil, can provoke side effects such as:

1. Feeling of nausea, often accompanied by vomiting.
2. Symptoms of tachycardia.
3. Bronchospasms.
4. Allergic manifestations in the form of a rash on the skin.
5. Pain in the epigastric region.
6. Frequent dizziness.
7. Hives.
8. Stomach ulcer.
9. Rapid development of thrombocytopenia.
10. A sharp decrease in blood pressure.
11. Diarrhea.
12. Hypocoagulation.
13. Anemia in a pronounced form.

Who should not take Agrenox?

For pregnant women, taking this drug is prohibited in the third trimester; in other cases, you should consult your doctor. The patient will not be able to replace Curantil with Agrenox for the following diseases:

• period of development of duodenal ulcer;
• stomach ulcer;
• boys under 18 years of age;
• in case of individual intolerance to the components of the drug;
• renal or liver failure;
• bronchial asthma;
• recent myocardial infarction;
• severe form of coronary heart disease.

Information for women! Curantil 75 and Agrenox should not be taken by mothers during lactation.

Indications for use of Curantyl

Curantil (according to the instructions for use) is used for the following indications:

• arterial, venous thrombosis;
• prevention of thromboembolism after cardiac surgery;
• ischemic disorders of blood flow in the brain;
• combination therapy of microcirculatory disorders.

If these violations are present, the doctor will select the correct dose of Curantyl or its analogue, the price of which may be lower.

Curantil is necessary primarily for people who have suffered a stroke, cerebral ischemia, or heart valve replacement surgery.

Curantil - instructions for use

Curantil is taken only orally. The tablet must not be crushed or chewed. The doctor selects a treatment regimen taking into account the disease and condition of the patient.

The average daily dose of Curantil and its analogues for the active substance in adults and children over 12 years of age is 75–225 mg. The required amount of the drug should be divided into 3 doses.

If necessary, the doctor can increase the daily dose to 600 mg. Self-adjustment of dosage is prohibited.

The use of Curantyl is contraindicated in case of allergies, heart attack, angina pectoris, myasthenia gravis, low blood pressure, lactation, recent heart attack, diseases with a risk of bleeding, bronchial asthma, in childhood (under 12 years).

Use caution when combining Curantil with anticoagulants, since such drugs enhance each other.

Combination with antacids (Maalox, Gaviscon, Rennie) leads to a decrease in activity.

The use of Curantil (25, 75 mg) and its analogues in tablets, including cheaper ones, rarely causes adverse reactions. Possible undesirable symptoms include dizziness, headaches, fainting, digestive disorders, and rash. A severe overdose can cause vomiting and dizziness.

How to take Curantil: before or after meals

Curantil is washed down with a small volume of clean water at room temperature. It is important to take the drug an hour before meals or in the morning on an empty stomach.

Violation of recommendations for taking the drug may lead to a decrease in its effectiveness.

Reviews

• Valentina Stepanovna, 49 years old. I never strive to purchase foreign medicines. Whatever they say, Russian pharmaceutical companies have long learned to do quality work. I have been using the drug Dipyridamole for quite a long time. It has a completely normal cost and has a quick effect. There is no need to complain yet, since the disease has really subsided.
• Olga Petrovna, 35 years old. The pregnancy was not easy, given that I was diagnosed with a disease such as varicose veins. The doctor immediately explained that I would have to take medications to avoid serious complications. She advised me to start using Curantil, but immediately warned that the medicine was not cheap. I had no doubt at all that this was what I needed to buy; I didn’t even think about looking for analogues. Believe me, savings are not always justified.
• Inna, 29 years old. I agree with the statement that you cannot save on health. But why pay more if you can buy a high-quality and inexpensive drug? I never understood this. Of course, if a person takes on the role of a doctor and selects the drug on his own, then nothing good can be expected. But if you ask a doctor about this, you can count on the fact that the doctor will be able to select not only an effective, but also a cheap remedy. I replaced Curantil with Clopidogrel.

Curantil's analogs

Curantil substitutes are drugs of various pharmacological groups that differ in composition, manufacturers, release forms and cost, but have common properties and effects. Analogs include the following:

• A synonym for Curantil is dipyridamole from Russian manufacturers.
• Antiplatelet agents with other active ingredients - Abciximab (Clotinab), Acetylsalicylic acid (Aspirin, Trombo ACC, Cardiomagnyl, Aspirin Cardio), Clopidogrel (Plavix, Trombonet), Eptifibatide, Apixaban (Eliquis), Rivaroxaban (Xarelto), Ticlopidine, Sulodexide (Wessel Due F).
• Anticoagulants - Warfarin (Coumadin), Acenocoumarol, Dabigatran (Pradaxa), Heparin (Fraxiparin, Clexane), Enoxaparin, Dalteparin.
• Nootropic analogs based on Pentoxifylline (Trental). Vinpocetine (Cavinton), Phenotropil, Citicoline, GABA, Phenibut, Piracetam, Glutamic acid, Mebicar.
• Other analogs that affect blood circulation are Actovegin, Armadin, Mexidol, Nucleo-CMF, Cytoflavin, Ascorutin, Diosmin (Phlebodia, Detralex, Vasoket) and other drugs.

Curantil analogs and average cost

Price

Curantil during pregnancy
The average cost of the drug is 520 rubles and differs depending on the form of release and the content of the active substance.

Curantil or Cardiomagnyl - which is better, what is the difference

Manufacturer: Takeda, Germany
Release form: tablets

Active ingredient: acetylsalicylic acid

Synonyms: Aspirin cardio, Aspecard, Cardiomagnyl forte, Lospirin, Thrombo ACC, Akard

Cardiomagnyl and Curantil are analogues in action. Both drugs are antiplatelet agents, prevent the formation of blood clots, and are taken orally. They contain different active substances and differ in manufacturers, costs, dosages and dosage regimens.

Doses of Cardiomagnyl: 150 mg - initial, 75 mg - maintenance. The peculiarity of this drug is the high risk of bleeding from the stomach and intestines, hematopoietic disorders, especially when used in high doses, and Reye's syndrome (in children, a symptom is profuse vomiting). The drug is not used in children and pregnancy, unlike Curantil 25 mg.

All substitutes for Curantil based on acetylsalicylic acid are selected by a doctor. The cost of such analogue products is much lower.

Acetylsalicylic acid or the respected Aspirin

Yes, yes, aspirin can not only lower the temperature and eliminate headaches, but also reduce blood viscosity. That is why it, like other analogues, can replace Curantil under such medical instructions. Regular use of Aspirin in reduced doses is used to thin the blood. By the way, most patients do not know that Aspirin has a wide range of contraindications and an even more extensive list of side symptoms. Without medical advice, its frequent use can severely damage your health, even leading to death. For comparison, Curantil is much better tolerated than acetylsalicylic acid and does not have such a harmful effect on the mucous membranes of the gastrointestinal tract. The price of the drug is a pittance. For 10 tablets you will have to pay 6 rubles.

Ginkgo biloba

Ginkgo
Biloba
is a herbal over-the-counter drug according to the classification classified as a group of chimes analogues.

Ginkgo Biloba is a plant with anti-aggregation properties; it is part of many combined nutritional supplements, and is also used as a stand-alone drug. It is very popular on the Russian pharmaceutical market, but is not approved as a medicine in the USA.

Preparations based on Ginkgo Biloba have a very wide range of prices, from 120 rubles ($2) to 1600 rubles ($25), it depends on the manufacturer and the number of tablets in the package.

It has no side effects as such, except for an allergy to the plant itself.

Fish fat

Also in the Russian Pharmacopoeia, in the group of analogues of chimes, Eikonol

– sold in the form of edible oil or in capsules, the active ingredient is
Omega 3 triglycerides
obtained from fish oil. Omega-3 triglycerides have a wide range of prices. If omega 3 triglycerides are purchased in the form of fish oil, it can be very inexpensive and sold as an edible oil. Unlike Ginkgo Biloba, fish oil is registered in the United States as a medicine for the treatment of heart disease.

Attention! Fish oil has contraindications!

Is it possible to replace chimes with fish oil?

Such a formulation of the question is possible only in the office of your attending physician, who bears full responsibility for the result. Both Curantil and its analogs, whether cheap or not, are often used in the treatment of serious diseases when the patient’s condition approaches critical.

Regardless of your knowledge, the drug Curantil and its main synonyms and analogue drugs require a doctor's prescription. Please consult your doctor for more detailed information.

Chime

Curantil has a vasodilating effect mainly on the small vessels of the heart, but in large doses it reduces resistance in the arterioles of the whole body and leads to a decrease in blood pressure. By expanding the diameter of the vessels, blood circulation increases and the flow of oxygen to the cells improves, therefore, the damaging effect of hypoxia or ischemia, which often occurs in heart disease, is neutralized. Curantil promotes the formation of collaterals (bypass paths) in ischemic areas, improves the functioning of the heart muscle, and reduces blood pressure.

Curantil improves microcirculation in the vessels of the brain, retina, and kidneys. During pregnancy, it slows down degenerative processes in the placenta, eliminates hypoxia of fetal tissue and restores placental blood circulation.

In addition, the drug prevents platelet aggregation and the formation of blood clots, especially when taken in combination with Curantyl and acetylsalicylic acid. With an increase in a single dose of the drug, a shortening of the lifespan of platelets and a suppression of the tendency to thrombus formation are observed. This effect is used in the treatment of patients with deep vein thrombosis. The combined use of Curantyl and acetylsalicylic acid is quite often prescribed in the complex treatment of atherosclerosis, as well as to reduce the risk of developing a recurrent stroke in patients with ischemic stroke.

The main active ingredient of Curantil is dipyridamole

, which helps to increase the production of interferon, a protein that has a pronounced antiviral effect. In this regard, Curantil can be used as a drug that increases the body's resistance to viral infections.

And the last area of ​​​​application of Curantil is stress echocardiography and dipyridamole-thallium-201 perfusion scintigraphy in the diagnosis of coronary heart disease in patients with unchanged coronary vessels. In this case, the drug is used as a diagnostic tool to determine the condition of the heart muscle, the safety of the valve apparatus and its contractile activity.

Curantil or Trental - which is better for blood vessels

Manufacturer: Sanofi, France, India
Release form: tablets, ampoules (solution for injection)

Active ingredient: pentoxifylline

Synonyms: Pentoxifyline, Agapurin, Vazonit, Pentilin, Latren

Trental is an analogue of Curantil in a number of common effects that both drugs have. The products improve blood rheology, increase its fluidity, and reduce the risk of blood clots.

Trental has a more pronounced effect on blood vessels, so it is the drug of choice for atherosclerosis and other diseases. The drug is a vasodilator (dilates blood vessels) for internal and injection administration. The choice depends on the form of the pathology and the patient’s condition. The daily dose is not more than 1200 mg.

The product is not used during pregnancy, unlike Curantil (with caution). In cases of severe vascular pathology, preference is given to Trental or a combination of drugs is used.

Analogs

If there is a need to replace the drug, then you should responsibly approach the issue of choosing a suitable analogue.
This is the only way to find a suitable remedy that will be effective and will not cause harm to the body. That is why it is recommended to discuss this issue with your doctor. In most cases, doctors use certain analogues that have already proven themselves to be effective. Such substitutes include: Dipyridamole, Trental, Pentoxifylline, Mexidol. It is these drugs that are widely used in modern medicine as substitutes for the drug Curantil.

Dipyridamole or Curantyl: which is better?

Two pharmaceutical companies are involved in the production of Dipyridamole. The first company is located in Belarus. The product produced by this company is considered one of the best analogues currently in use. It has a relatively low cost and is ideal for the treatment of angina pectoris, as well as the prevention of diseases such as thrombosis. But during pregnancy, this drug is strictly prohibited.

Russian manufacturers are also involved in the production of Dipyridamole. Their product is the cheapest analogue and can be used for the treatment and prevention of stroke and complications after heart surgery

You can use the product during pregnancy, but with great caution. If the period is short (up to 12 weeks), then you will have to stop using the medication

Curantil or Trental: what to choose

Curantil, which has analogues, is often compared with a remedy such as Trental

But if you compare these two medications, you first need to pay attention to:

• difference in composition;
• differences in the list of contraindications.

The drug Trental has another active ingredient - pentoxifylline. But, despite the difference in composition, the drug has an effect completely similar to that characteristic of Curantil.

The only significant drawback is that this analogue cannot be prescribed to pregnant and lactating girls. It can even pass into breast milk. Therefore, when it comes to choosing therapy for pregnant women, this must be taken into account.

Actovegin or Curantil: which is better?

This is the most preferred analogue and not only because of its relative cheapness. The fact is that Actovegin is the only substitute in which the active ingredient is a special extract from the blood of calves. This extract is completely free of protein, so it is not capable of harming the patient’s body. Consequently, all possible risks are reduced to zero.

The main advantage of the product is its wide spectrum of action. The drug can be used not only to combat diseases such as ischemia and stroke. It is also quite often used to strengthen the immune system or increase the body's resistance to infectious diseases.

Pentoxifylline

A drug whose active ingredient is pentoxifylline has already been reviewed. But there is also a drug of the same name. It has indications for use identical to those characteristic of Curantil.

However, the product is not used so often. The reason for this is the fact that the medicine has many side effects. Moreover, the likelihood of adverse reactions is very high. Therefore, doctors try, if possible, not to prescribe this drug to patients, especially if their body is seriously weakened by the disease and is not able to fight the aggressive effects of the drug.

Mexidol

This remedy is widely used for the treatment of atherosclerosis, withdrawal syndrome, and circulatory disorders. Taking sorbents together with this drug is also allowed. In addition, the drug is actively used in the treatment of other diseases:

• vegetative-vascular dystonia;
• tissue hypoxia;
• gingivitis;
• caries;
• stomatitis.

However, the appointment should be carried out only on the condition that the patient’s condition is constantly monitored by the attending physician. If any negative reactions from the body are detected, you must immediately stop using the product.

Curantil or Dipyridamole - which is better during pregnancy

Manufacturer: Vertex, Obolenskoye FP, Russia
Release form: tablets, ampoules

Active ingredient: dipyridamole

Synonyms: Curantil, Pencelin, Dipyridazole-FPO

Curantyl and Dipyridamole are synonyms with the same active ingredient. The effects of use are identical. Differences in manufacturers, cost and quality of raw materials used in production.

Both analogues are used with caution during pregnancy. If a pregnant woman (2nd and 3rd trimester) has blood flow disturbances in the placenta, slow blood circulation, varicose veins and other complications, products based on Dipyridamole are used. According to patient reviews, the drug is well tolerated and gives a quick effect.

Curantil or Clexane - which is better during pregnancy

Manufacturer: Sanofi, France
Release form: solution for injection in syringe doses

Active ingredient: enoxaparin (low molecular weight Heparin)

Synonyms: Enoxaparin, Novoparin, Flenox, Enixum, Quadraparin, Anfibra

Clexane is a powerful injectable anticoagulant. Prescribed for the prevention of thrombosis, including in pregnant women. The average therapeutic dosage is 2000 MO or 20 mg subcutaneously. Depending on the degree of the disease, doses vary. Treatment is recommended under the supervision of a physician.

When using the medication in pregnant women, monitoring is necessary due to the risk of bleeding if the analogue is used before childbirth.

Before replacing Curantil with Clexane to thin the blood, the doctor will assess the patient’s condition and the degree of the disease. In most cases, the drug is well tolerated and rarely causes side effects. In some cases, it is enough to administer the medicine internally to maintain the properties of the blood.

The cost of Clexan is higher than its analogue Curantil.

When not to take

What to replace

Curantil, like any other drug, has a number of contraindications, so it cannot be prescribed to every pregnant woman. Expectant mothers who have:

• low blood pressure. The action of Curantil is based on the dilation of blood vessels and a decrease in pressure;
• liver diseases, liver failure. Dipyridamole (the active ingredient of the drug) is converted in the liver;
• heart failure, since drug components accumulate in the heart muscle;
• diseases associated with a high risk of bleeding (intestinal and stomach ulcers). The drug thins the blood, increases the risk of bleeding;
• renal failure, since part of the active substance is excreted through the kidneys;
• individual intolerance to the components of the drug.

The components of the drug enter the blood and are transported throughout the body, so any organ that has any dysfunction can be “under attack”.

Side effects

Side effects from taking Curantil often include nausea, dizziness, weakness, and headache.

. This is how the body reacts to a decrease in blood pressure. The ailment goes away on its own and does not require specific therapy.

An allergic reaction in the form of skin rashes may occur to certain components of Curantil; if such symptoms occur, you should stop taking the drug and consult a doctor.

When taking Curantyl, you should limit or completely eliminate coffee and tea from your diet, since these drinks reduce the vasodilator effect of the drug.

The effect of Curantil is enhanced by drugs that lower blood pressure, so you should not take them together because of the possibility of a sharp decrease in blood pressure and worsening well-being.

Risks to the fetus

Scientists have not conducted studies whose results could guarantee the absolute safety of Curantil for an unborn child

, therefore the instructions say that use is possible if the expected benefit outweighs the risk. Only a doctor can weigh the pros and cons, based on the results of laboratory tests and the individual characteristics of the body. You do not need to prescribe this drug yourself.

The drug has not passed a single full-fledged test - all articles are either from the CIS countries or China. In Western Europe and the USA, Curantil and Actovegin are not used. Drugs containing animal ingredients are prohibited in developed countries due to mad cow disease.

There is an opinion that the medical effectiveness of Actovegin and Kurantil has not been proven, since they have not been subjected to clinical research.

Curantil during pregnancy is one of the drugs that is most often prescribed to pregnant women. The reasons for this prescription are different, including headaches, high blood pressure, and the development of edema.

Let us consider in more detail the description of the drug, indications for its use, effectiveness and possible side effects.

The main active ingredient in Curantil is dipyridamole. Its function is to prevent platelets from sticking together. As a result:

• blood thinning;
• improvement of microcirculation;
• improvement of oxygen metabolism in tissues;
• strengthening the walls of blood vessels and capillaries.

Another effect of dipyridamole is vasodilation and, as a result, a decrease in blood pressure.

The drug is prescribed not only for therapy purposes, but also for prevention. However, its use without a doctor's prescription is strictly prohibited.

How many tablets to take, what dosage is needed - all this is decided by the doctor who is seeing the pregnant woman.

Curantil or Trombo ACC - which is better?

Manufacturer: Lannacher, Germany
Release form: tablets

Active ingredient: acetylsalicylic acid

Synonyms: Akard, Aspecard, Aspirin cardio, Cardiomagnyl, Lospirin, Aspirin, Acetylsalicylic acid

Thrombo ACC is an antiplatelet drug, an analogue of Curantil, which helps prevent thrombosis, is prescribed in low doses of 100–300 mg per day to thin the blood, especially in cases of atherosclerosis, angina, and ischemia. The drug can be a substitute for Curantil according to the doctor’s recommendations in case of intolerance or other reasons.

Acetylsalicylic acid in Thrombo ACC can cause ulcers and bleeding, as well as Reye's syndrome in children. To reduce their likelihood, it is recommended to take such analogues with food.

Curantil or Xarelto - which is better?

Manufacturer: Bayer, Germany
Release form: tablets

Active ingredient: rivaroxaban

Synonyms: Rivaroxaban

Xarelto is an expensive analogue from the group of antiplatelet agents that affect the coagulation factor. Take 10-30 mg orally per day. Differences between analogues in active substances and mechanisms of action.

A doctor can replace Curantil with Xarelto if there are indications, for example, intolerance to the drug or other disorders. Xarelto is a relatively safe and effective product from a foreign manufacturer.

Persantine

The country of origin of Persantine is Spain. This cheap analogue of the drug Curantil allows you to completely replace it, since it uses the same active ingredient - dipyridamole. The peculiarity of the medicine is that in order to avoid dyspeptic symptoms, doctors advise taking it with milk.

It is not advisable to consume natural coffee or tea at the same time as Persantine, since in this case its properties, as well as the effect of Curantyl, will be weakened.

Who should not take Persantine?

Like Curantil, the analogue Persantine has a number of contraindications. The drug should not be taken for diseases such as:

1. Acute myocardial infarction.
2. Peptic ulcers of the stomach and duodenum.
3. Unstable angina.
4. Individual intolerance to the active substance.
5. Severe arrhythmia.
6. Arterial hypotension.
7. Hemorrhagic diathesis.

Indications for use

This cheap analogue can replace the drug Curantil in the following cases:

• thrombosis;
• prevention of coronary artery bypass grafts, myocardial hypertrophy and stent occlusion;
• prevention and treatment of ARVI;
• cerebrovascular accident;
• platelet suppression syndrome in a child;
• thromboembolism.

Chimes or Aspirin - which is better?

Manufacturer: Bayer, Germany
Release form: tablets

Active ingredient: acetylsalicylic acid

Synonyms: Aspirin Cardio, Aspecard, Cardiomagnyl, Thrombo ACC, Cardisave, Akard, Godasal, Lospirin

All analogues of Curantil based on Acetylsalicylic acid are cheaper drugs for internal use, which in low doses thin the blood and prevent thrombosis.

Aspirin Cardio is recommended to take 100-300 mg per day. In high doses, a blood thinner is not used. Before replacing, you should evaluate the risks of using Aspirin. This analogue increases the risk of bleeding and stomach ulcers. For prevention, the drug should be taken with food.

In childhood, the likelihood of Reye's syndrome is high. In pregnant women, preference should be given to the safer analogue Curantil.

Answers on questions

Does Curantil thin the blood or not?

Curantil (Dipyridamole) thins the blood by preventing platelets from sticking together to form a clot - a thrombus.

Curantil 25 or 75 mg, what is the difference?

The only difference is in the dosage of the active substance Dipyridamole in one tablet (dragée).

Does Curantil lower blood pressure or not?

The drug has a mild hypotensive effect due to a slight expansion of peripheral vessels.

Is Curantil an anticoagulant or not?

Curantil is not an anticoagulant, that is, it does not affect coagulation factors. It is an antiplatelet agent that affects platelets.

Does chimes increase or decrease blood pressure?

The drug does not have antihypertensive properties due to its dilating effect on blood vessels.

Is Kurantil an antibiotic or not?

Curantil is not an antibacterial agent, it is an antiplatelet drug.

Release form and composition

The manufacturer produces the drug in the following dosage forms:

• Curantil 25 - in the form of dragees, 100 pieces in glass bottles No. 1 in a box;
• Curantil N (N) 25 – in the form of coated tablets, 120 pieces in glass bottles No. 1 in a box;
• Curantil N (N) 75 – in the form of coated tablets, 40 pieces per box.

According to the INN (international nonproprietary name), all dosage forms of the drug Curantil include the active ingredient dipyridamole (dipyridamole) in different mass parts.

• 1 tablet Curantil 25 contains 25 mg of dipyridamole.
• 1 tablet N 25 contains 25 mg of dipyridamole.
• 1 tablet N 75 contains 75 mg of dipyridamole.