Vormil - description of the drug, instructions for use, reviews

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Manufacturers: Mili Healthcare

Active ingredients

• Not indicated. See instructions

Disease class

• Not indicated. See instructions

Clinical and pharmacological group

• Not indicated. See instructions

Pharmacological action

• Antihelmintic (anthelminthic)

Pharmacological group

• Not indicated. See instructions

Compound

Each chewable tablet contains the active substance albendazole in an amount of 400 mg.
As well as auxiliary components: corn starch, talc, microcrystalline cellulose, colloidal silicon dioxide, aspartame, magnesium stearate, sodium propyl hydroxybenzoate, starch glycolate and sodium methylhydroxybenzoate, and mixed fruit essence. A 10 ml bottle of Vormil suspension contains the same amount of active and excipients, but also additional components: polysorbate 80 , raspberry essence and purified water.

Pharmacodynamics and pharmacokinetics

The effectiveness of albendazole is manifested in the treatment of various parasitic lesions affecting tissues and the intestinal area. Adult helminths, as well as eggs and larvae, show sensitivity to it. Thanks to the anthelmintic effect of albendazole, tubulin polymerization is suppressed , which destroys the metabolism of helminths and causes their death.

The action of this drug is aimed at a large number of intestinal helminths and protozoa. It also helps get rid of tissue worms and so on. Treatment with Vormil leads to a reduction in size or elimination of granular echinococcus cysts.

When taking albendazole , its poor absorption from the gastrointestinal tract was noted. If you simultaneously consume fatty foods, this significantly increases the absorption of the main substance. After initial passage through the liver, it undergoes rapid metabolism. The main metabolite is albendazole sulfate , the activity of which is 50% higher than the primary substance. The half-life is 8.5 hours. This happens mainly with bile or urine. If the drug is taken in a high dose over a long period of time to treat cysts, the metabolites from the cysts may be cleared within a few weeks.

Suspension Vormil

Instructions for medical use of the drug

Description of pharmacological action

Vormil is an anthelmintic drug with a broad spectrum of action. The active substance is albendazole. Albendazole is effective against tissue and intestinal forms of parasitic diseases. It acts on both adult helminths and their larvae and eggs. The anthelmintic effect is due to the ability of albendazole to suppress the polymerization of tubulin, which causes a disruption in the metabolism of helminths with their subsequent death.

Indications for use

For parasitic infestations (hookworm, enterobiasis, necatoriasis, taeniasis, strongyloidiasis, hymenolepiasis, ascariasis, trichinosis, capillarosis, trichinosis, cutaneous migratory larvae, clonorchiasis, gnathostomiasis, toxocariasis, giardiasis in children).

Release form

Suspension

Pharmacodynamics

Vormil is an anthelmintic drug with a broad spectrum of action. The active substance is albendazole. Albendazole is effective against tissue and intestinal forms of parasitic diseases. It acts on both adult helminths and their larvae and eggs. The anthelmintic effect is due to the ability of albendazole to suppress the polymerization of tubulin, which causes a disruption in the metabolism of helminths with their subsequent death. Shows action against intestinal helminths (nematodes Enterobius vermicularis, Ascaris lumbricoides, Triсhiurus triсhiura, Strongiloides stercoralis, Necator americanus, Cutaneous Larva Migrans Ancylostoma duodenale; cestodes Taenia solium, Hymenolepsis nana, Taenia saginata; trematodes Clonorchis sinensis and Opisthorhis viverrin i), as well as protozoa (Giardia lamblia). Active against tissue helminthiases (Echinococcus granulosus - cystic echinococcosis and Echinococcus multilocularis - alveolar echinococcosis). Albendazole is also effective in the treatment of infestation of T. Solium larvae (neurocystecercosis) and Gnatostoma spinigerum (capillariasis). When using Vormil, cysts of granular echinococcus are reduced in size or eliminated.

Pharmacokinetics

After internal administration, albendazole is poorly absorbed from the gastrointestinal tract - up to approximately 5%. When consuming fatty foods simultaneously with albendazole, an increase in the absorption of the substance is observed. Upon initial passage through the liver, it is quickly metabolized. The main metabolite, albendazole sulfate, is active at 50% of the effect of the primary substance. The half-life is 8.5 hours. Albendazole metabolites are excreted from the body with bile (mainly) and urine (small amounts). When taken for a long time (in large doses for the treatment of cysts), the removal of metabolites from cysts is observed over several weeks.

Contraindications for use

• hypersensitivity reactions to albendazole or other components of Vormil; • prenatal period.

Side effects

From the digestive system: vomiting, dry mouth, stomatitis, heartburn, flatulence, nausea, abdominal pain, diarrhea, constipation. From the nervous system: headache, drowsiness or insomnia, dizziness, disorientation, confusion, hallucinations, convulsions. From the organ of vision: decreased visual acuity. Hypersensitivity reactions: urticaria, dermatitis, itching, pemphigus, fever. Blood system: pancytopenia, leukopenia.

Directions for use and doses

The dose is set individually. The suspension is indicated for children from the 1st year of life!

Overdose

In case of an overdose of Vormil, the following symptoms are possible: blurred vision, vomiting, nausea, drowsiness, visual hallucinations, dizziness, hepatomegaly, speech impairment, loss of consciousness, jaundice, orange or brown-red color of urine, skin, saliva, sweat, tears and feces. Treatment: gastric lavage, administration of enterosorbents, supportive and symptomatic therapy.

Interactions with other drugs

It is possible to increase the concentration of albendazole metabolites when combined with praziquantel, cimetidine and dexamethasone.

Storage conditions

In a place protected from children and access to light at room temperature.

ATX classification:

P Antiparasitic drugs, insecticides and repellents

P02 Anthelmintic drugs

P02C Preparations for the treatment of nematodes

P02CA Benzimidazole derivatives

P02CA03 Albendazole

Indications for use of the drug

The main purpose of the drug is the treatment and prevention of worms . By taking Vormil for prophylaxis, you can prevent the penetration of various forms of parasites into the body. Although it is still recommended to conduct a preliminary examination for their presence.

Treatment with this remedy is carried out for:

• hookworm;
• enterobiasis;
• necatorosa;
• strongyloidiasis;
• ascariasis;
• trichinosis;
• capillarosis;
• cutaneous migratory larvae;
• clonorchiasis;
• giardiasis in children and so on.

Indications.

Intestinal forms of helminthiasis and skin syndrome Larva Migrans (short-term treatment with small doses): enterobiasis, hookworm and necatoriasis, hymenolepiasis, taeniasis, strongyloidiasis, ascariasis, trichuriasis, clonorchiasis, opisthorchiasis, skin syndrome Larva Migrans, giardiasis in children.

Systemic helminthic infections (long-term treatment with high doses):

cystic echinococcosis (caused by Echinococcus granulosus):

- if surgical intervention is not possible;

- before surgery;

- after surgery, if preoperative treatment was short, if the spread of helminths is observed or live forms were found during the operation;

— after percutaneous drainage of cysts for diagnostic or therapeutic purposes;

alveolar echinococcosis (caused by Echinococcus multilocularis):

- for inoperable diseases, in particular in cases of local or distant metastases;

— after palliative surgery;

after radical surgery or liver transplantation for neurocysticercosis (caused by Taenia solium larvae):

- with arachnoid or intraventricular cysts;

- with racemotic cysts;

capillarosis (caused by Capillaria philippinensis), gnathostomosis (caused by Gnathostoma spinigerum and related species), trichinosis (caused by Trichinella spiralis and T.pseudospiralis), toxocariasis (caused by Toxocara canis and related species).

Wormil for children

Quite often, these deworming tablets are prescribed to children. According to the instructions for children, this medicine is recommended for use from 2 years of age. You can take the drug in any form, but a suspension is best suited for treating young patients, as it has low toxicity and is almost safe for the child’s body. When Vormil is used to treat giardiasis , take 1 tablet for 5 days. At the same time, numerous reviews indicate the high effectiveness of this drug.

Contraindications for use:

• age less than 2 years;
• lactation, pregnancy;
• drug intolerance;
• prenatal period.

Similar drugs:

• Vormil Chewable tablets
• Pyrantel Oral suspension
• Decaris Oral tablets
• Helmintox Oral suspension
• Wormin Oral tablets
• Vermox Oral tablets
• Biltricide Oral tablets
• Mebendazole Oral tablets
• Piperazine Tablets
• Pyrantel Pamoate Substance-powder

** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use the drug Vormil, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.

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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Vormil is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!

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Side effects

Sometimes treatment with Vormil may be accompanied by adverse events affecting digestive activity: vomiting, dry mouth, stomatitis, heartburn, flatulence, nausea, abdominal pain, diarrhea and constipation.

Nervous system reactions include: headache, drowsiness or insomnia, dizziness, disorientation, confusion, hallucinations and convulsions.

It is possible: visual impairment , as well as the development of urticaria, dermatitis, itching, pemphigus, and so on.

Instructions for Vormil (Method and dosage)

If tablets are used for treatment, you need to remember that they are intended to be chewed. At the same time, the instructions for use of Vormil inform that the dosage is determined individually depending on age and type of disease.

For example, in the treatment of hookworm, ascariasis, enterobiasis, trichinosis for children over 2 years of age and older patients, a daily dose of 400 mg is prescribed, which is taken for 3-5 days. In any case, a specialist determines how to take this or that form of the drug for a specific disease. If necessary, after a certain break, the therapeutic course is repeated.

Method of administration and dose.

The dose is set individually.

For children from 1 to 2 years old with enterobiasis, hookworm, necatoriasis, ascariasis, trichinosis, the drug is prescribed 5 ml of suspension (200 mg) once a day once. For adults and children over 2 years of age with enterobiasis, hookworm, necatoriasis, ascariasis, trichinosis, the drug is administered orally in 10 ml of suspension (400 mg) once a day once.

If a diagnosis of strohypoidosis, taeniasis and hymenolepiasis has been established, the drug is administered to adults and children over 2 years of age, 10 ml of suspension (400 mg) once a day for 3 days. For hymenolepidosis, a repeated course of treatment is recommended in the interval from the 10th to the 21st day after the previous course.

For opisthorchiasis and clonorchiasis, adults and children over 2 years of age are prescribed the drug 10 ml of suspension (400 mg) 2 times a day for 3 days. This scheme is also effective for mixed infestations of Opisthorhis viverrini and Clonorchis sinensis.

For giardiasis, children aged 2 to 12 years are prescribed the drug 10 ml of suspension (400 mg) once a day for 5 days.

For Larva Migrans skin syndrome, use the drug in adults and children over 2 years of age, 10 ml of suspension for 1-3 days.

Systemic helminthic infections (long-term treatment with high doses).

The drug is taken with food.

For children under 6 years of age, administration of the drug in high doses is not recommended. The dosage regimen is set individually depending on age, body weight, and the severity of the infection.

The dose for patients weighing more than 60 kg is 400 mg (10 ml suspension) 2 times a day. For body weight less than 60 kg, the drug is prescribed at a rate of 15 mg/kg/day. This dose should be divided into 2 doses. The maximum daily dose is 800 mg.

When treating patients with neurocysticercosis, appropriate corticosteroid and anticonvulsant therapy should be prescribed. Oral and intravenous corticosteroids are recommended to prevent cases of cerebral hypertension during the first week of treatment.

Elderly patients

Experience with the drug in the treatment of elderly people is limited. No dose adjustment is required, but albendazole should be used with caution in the treatment of elderly patients with impaired liver function.

Kidney failure

Since albendazole is excreted by the kidneys in very small quantities, no dose adjustment is required for the treatment of this category of patients, however, if there are signs of renal failure, such patients should be closely monitored.

Liver failure

Because albendazole is extensively metabolized in the liver to a pharmacologically active metabolite, impaired liver function may have a significant impact on its pharmacokinetics. Therefore, patients with altered liver function tests (increased transaminase levels) at the start of albendazole should be carefully examined; in the case of a significant increase in transaminase levels or a drop in blood counts to a clinically significant level, treatment should be discontinued.

Overdose

In cases of overdose with Vormil, the following symptoms may develop:

• vision problems;
• vomiting;
• nausea;
• drowsiness;
• dizziness;
• speech disorders;
• loss of consciousness and so on.

To eliminate undesirable effects, the following are prescribed: gastric lavage, enterosorbents and other therapy depending on the symptoms.

Analogues of Vormil

Level 4 ATC code matches:
Medamin

Vermakar

Nemozol

Vermox

Aldazole

Zentel

Vormin

Sanoxal

Mebendazole

The most popular analogues of this drug are Aldazol, Nemozol, Medizol, Farmox, Zentel and Vermox . However, it is not recommended to replace the drug yourself, as this remains within the competence of a specialist.

Wormil or Vermox - which is better?

When treating helminthic infestations, a specialist usually prescribes Vormil or Vermox . Therefore, patients are often concerned about the question, which of these drugs is better? According to some doctors and patients who took both medications, Vormil has a wider range of effects on parasites compared to Vermox . It has also been established that the body perceives Vormil better.

Features of application.

Short-term treatment of intestinal infections and skin syndrome Larva Migrans.

To prevent use of Vormil in early pregnancy, women of reproductive age should be treated in the first week after menstruation or after a negative pregnancy test. Reliable contraception is necessary during therapy. Treatment with albendazole may reveal the presence of pre-existing neurocysticercosis, especially in areas with high rates of infection by Tenia solium strains. Patients may experience neurological symptoms such as seizures, increased intracranial pressure and focal symptoms due to the inflammatory response caused by the death of parasites in the brain. Symptoms may occur quickly after treatment, so appropriate therapy with corticosteroids and anticonvulsants should be started immediately.

Long-term treatment of systemic helminth infections.

Treatment with albendazole is accompanied by a mild to moderate increase in liver enzyme levels, which usually normalizes after cessation of treatment. Therefore, liver enzyme levels should be checked before each course of treatment and at least every 2 weeks during treatment. If liver enzyme levels increase significantly (more than 2 times the upper limit of normal), albendazole treatment should be discontinued. Treatment can be resumed once enzyme levels have normalized, but the patient's condition should be carefully monitored.

Albendazole can cause bone marrow suppression, so the patient's blood should be tested both at the start of treatment and every 2 weeks during the 28-day cycle. Patients with liver disease, including hepatic echinococcosis, are more prone to bone marrow suppression, resulting in pancytopenia, aplastic anemia, agranulocytosis and leukemia, which necessitates close monitoring of blood counts. If a significant drop in blood counts occurs, treatment should be stopped.

Can be used during mandatory deworming (i.e. prophylaxis) before vaccination, as well as for preventive treatment and twice a year.

Patients with neurocysticercosis who are treated with albendazole may experience symptoms (eg, seizures, increased intracranial pressure and focal symptoms) associated with the inflammatory response caused by the death of parasites. This should be treated with corticosteroids and anticonvulsants. To prevent the occurrence of cases of increased cerebral pressure during the first week of treatment, it is recommended to use oral or intravenous corticosteroids.

To prevent the use of Vormil for women in early pregnancy, as well as women of reproductive age, you should:

- start treatment only after a negative pregnancy test;

- warn about the need to use effective contraception during treatment and for a month after its discontinuation.

Reviews about Vormil

The high popularity of this drug is the reason that reviews of Vormil are quite common. At the same time, reviews from doctors and patients contain information about the good effectiveness of this product. Often the whole family is treated with this drug, and test results show that the tablets help quickly get rid of the problem.

However, many parasitologists, noting the high activity of Vormil against most parasites, simultaneously notice a decrease in immunity and the development of undesirable reactions.

Almost every forum for children contains such information, where childhood diseases and ways to get rid of worms are discussed. Therefore, the choice of drug must be made only together with a specialist, after passing all the tests.

Note!

Description of the drug Vormil Susp. yelled 200mg/5ml fl. 10ml on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.

Wormila price, where to buy

It should be noted that the price of Vormil, given its high efficiency, is quite acceptable. By the way, in Russia you can order it on a specialized website and receive it by courier delivery at a cost of 250 rubles. In pharmacies you can buy its analogues - Nemozol and Albendazole .

In Ukraine, in cities such as Kharkov and Donetsk, the price of Vormil varies between 41-50 UAH.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine

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