Androdosis is a complete balanced complex for improving spermatogenesis

Compound

Shelf life and storage conditions

AndroDoz should be stored in its original packaging in a dry, cool place out of the reach of children. Make sure that the packaging is not exposed to sunlight or bright light. The price of AndroDoz in Moscow pharmacies is approximately 2400-2800 per pack. The shelf life indicated on the packaging is 2 years. The closest analogue of AndroDoz is Profertil, the cost of which is approximately 4,700 rubles for package No. 60, and 12,000 rubles for package No. 180. Both drugs are identical in composition, but the analogue is produced in Austria, which leads to a high cost.

Effect on the body

AndroDoz is a balanced combination of 9 active substances that improve sperm quality by affecting various stages in the development of spermatogenesis disorders, which is especially important given the polyetiological nature (simultaneous presence of several causes) of this condition.

AndroDoz helps improve sperm motility and the number of viable forms.

Helps reduce the viscosity of ejaculate.

Affects an increase in testosterone levels.

Mechanism of action

AndroDoz acts in several directions thanks to its balanced composition and unique formula, which is important given the polyetiological nature of infertility. Each component of the drug performs its own function, and together the elements contribute to the healing of the entire body. In the treatment of male subfertility (relative infertility, limited ability to conceive a child), AndroDoz helps to increase the number of viable forms of sperm, increase the fertilizing function of sperm and its cryotolerance, which is indispensable when carrying out assisted reproduction procedures.

Component Properties

L-carnitine. In the male reproductive system, L-carnitine is concentrated in the epididymis and sperm. This is a natural vitamin-like substance (vitamin B11 or vitamin T), which provides energy for the entire process of spermatogenesis (the process of creating sperm) and directly affects a man’s ability to conceive a child. L-carnitine is able to suppress oxidative stress, which is important in the development of idiopathic male infertility. Taking carnitine improves motility and increases sperm production.

L-arginine. It is a biologically active isomer of the conditionally essential amino acid arginine.

Seminal fluid proteins up to 80% consist of L-arginine, and therefore this amino acid occupies an important place in the male reproductive system, and its deficiency can lead to impaired spermatogenesis and infertility. Taking L-arginine has a beneficial effect on prostate health and enhances spermatogenesis (increases sperm production and quality). In addition, L-arginine is actively involved in the regulation of sexual function; being a precursor of nitric oxide, it maintains good blood flow in the male genital organs and helps normalize erection.

Coenzyme Q10. Coenzyme Q10 (ubiquinone) is an essential element in the synthesis of biochemical energy carriers. Taking coenzyme Q10 is effective during high physical activity and increases endurance.

Coenzyme Q10 is a powerful antioxidant, in addition, it has the ability to restore the activity of other antioxidants, in particular α-tocopherol (vitamin E).

Coenzyme Q10 has clinically proven synergism with L-carnitine. Thanks to the above properties, this substance helps to increase sperm production and improves their motility.

L-carnosine. It is a natural component of human tissue and a powerful water-soluble antioxidant. At the same time, L-carnosine also enhances the effect of fat-soluble antioxidants, such as α-tocopherol.

In the experiment, it neutralizes heavy metals and prevents poisoning of the body by various toxins. L-carnosine has been shown to protect the reproductive system from harmful influences, stimulate spermatogenesis and improve sperm motility.

"Vitasil-Se (selenium)-S." It is an optimal source of selenium, its production uses inactive whole yeast cells (Saccharomyces cerevisae), also known as baker's yeast, which during the fermentation process transforms inorganic selenium into organically bound "Vitasil-Se (selenium)-C" is rich in selenium used in food, has the greatest digestibility by the human body.

Selenium is a vital trace element involved in the entire life cycle - from conception to aging and is part of a number of hormones and enzymes associated with almost all organs and systems of the human body, a powerful antioxidant, the main role of which is to suppress the process of lipid oxidation and protect cells from destructive action of free radicals. In experiments, it is able to protect spermatogenesis during acute and chronic intoxication. It has a pronounced synergistic effect with vitamins A and E, reduces their breakdown, while reducing the body's need for these vitamins, and is necessary for the normal functioning of the male reproductive system.

The use of selenium in organic form is the most physiological, it ensures gradual absorption in the intestine, independent of the content of vitamins, as well as a uniform content of this microelement in the blood plasma for a long time (a selenium depot is created in the body).

Licorice (Glycyrrhiza glabra). Licorice roots and rhizomes contain glycyrrhizic acid, as well as flavonoids, which together have antiviral, antifungal, anti-inflammatory, antiallergic, immunomodulatory, and tonic effects.

Glycyrrhizic acid suppresses the activity of a component of the coagulation system - thrombin (including that present in sperm and involved in the process of sperm thickening) - has a mucolytic effect (thin the sputum), stimulates the production of the hormone secretin, which helps liquefy the secretions of the pancreatic ducts, bile ducts, Brunner's glands .

Puramex ZN (zinc lactate). It is the lactic acid form of zinc, most easily absorbed in the digestive tract.

Zinc is a vital trace element that can be found in almost any tissue of the body. Zinc is absolutely essential for cellular respiration, oxygen utilization, reproduction of genetic material (DNA and RNA), maintaining the integrity of cell walls and neutralizing free radicals.

In the human body, zinc is concentrated in all organs and tissues, incl. testicles, epididymis, prostate gland, and is found in fairly large quantities in sperm.

Zinc is one of the most important trace elements for the normal functioning of the male reproductive system, since it starts and supports the production of the male sex hormone - testosterone and activates spermatogenesis.

Zinc activates glutathione peroxidase, which is necessary for the normal maturation and motility of sperm, and also participates in the regulation of the activity of other spermoplasmic enzymes, and helps regulate the processes of coagulation and liquefaction of the ejaculate.

This explains the development of infertility, slower puberty and decreased sexual abilities that occur with zinc deficiency.

Zinc deficiency often develops with increased excretion of this microelement under the influence of stress, electromagnetic radiation (when working at a computer, spending a long time near a switched-on TV, etc.), as well as under the influence of toxic substances, heavy metals, pesticides and other environmental pollutants .

Zinc and vitamin A are biochemically interdependent: vitamin A promotes the absorption of zinc, and without zinc the absorption of vitamin A is impossible. The simultaneous intake of zinc and vitamin A is relevant for male infertility and spermatogenesis abnormalities caused by various factors, in particular, infectious diseases, the influence of harmful production, ionizing radiation.

Vitamin E (tocopherol). It is an important element of the antioxidant system: prevents damage to cell walls by neutralizing hydrogen peroxide and other reactive oxygen species; necessary for the growth of new cells and the normal functioning of the immune system.

It has been proven that taking vitamin E reduces the severity of oxidative stress in testicular tissue, increases sperm motility and has a positive effect on their ability to penetrate the egg.

Vitamin E has a synergistic effect with retinol and selenium, i.e. when taken simultaneously, these substances exhibit pronounced effectiveness in lower doses than when used separately, due to the mutual prevention of oxidation (destruction) both in the intestines and in the tissues.

Vitamin A (retinol). An important part of the antioxidant system that protects cell membranes from oxidation, affects protein synthesis and supports reproductive functions. The presence of vitamin A in seminal fluid is also necessary for normal spermatogenesis and maintenance of sperm motility.

Improves the absorption of zinc and enhances its antioxidant effect.

Application

The method of using AndroDoz is as follows: take 4 capsules daily with meals. It is more convenient to take the daily dose twice, 2 capsules twice a day. The recommended minimum treatment period is a month. Then you can take a two-week break and repeat the monthly course again according to the previous scheme. The product is sold in convenient packaging - 4 compartments for capsules on a blister, just for daily use.

There is no information about the consumption of alcohol during treatment with dietary supplements, but everyone knows that the harmful effects of ethanol on the cells of organs and tissues can nullify any treatment. AndroDoz is not a drug, but before using it you should consult a specialist.

Despite the presence of instructions for using AndroDoz in the package, some patients skip the next dose of the drug. In this case, you should not “catch up” and take a double dosage, but continue to use the capsules as usual and at the recommended dose.

AndroDoz instructions for use

Release form Capsules. Composition 1 cap. contains arginine-alpha-keto-glucorate (AAKG), carnitine, coenzyme Q 10, carnosine, selenomethionine, licorice, puromex zinc extract, vitamin E, vitamin A. Auxiliary components: lactose.

Packaging 60 pcs per pack.

Pharmacological action The substances included in the AndroDoz dietary supplement have the following effect: Arginine, 1-amino-4-guanidinovaleric acid. This is one of the essential amino acids that can be converted into nitric oxide, which, in turn, serves as a regulator of the most important functions of the cardiovascular and immune systems, liver, and reproductive organs. Sperm proteins contain up to 80% of the total amount of arginine, and its deficiency can lead to pathozoospermia. Arginine stimulates the production of the hormone testosterone and, in combination with alpha-ketoglucorate, increases the content of nitric oxide, significantly affecting erectile function. Carnitine, a special amino acid with vitamin-like properties (B11 or T). Improves male reproductive function. For the normal functioning of the reproductive system, prostate secretions must contain carnitine in fairly high concentrations. The amino acid promotes sperm maturation. It has been proven that acid concentrations are significantly lower in infertile men compared to those with healthy reproductive capacity. Coenzyme Q10 (ubiquinone, coenzyme Q10). The structure of the substance is close to vitamins K, and is present in most human tissues. Has antioxidant properties, provides protection against free radicals. Coenzyme Q10 helps increase endurance and supplies the body with the energy necessary for physical activity. Preparations containing this substance can slow down the aging of cells, maintaining them at an energy level. In men with pathozoospermia of unknown origin, after the administration of coenzyme Q10, the number of motile sperm increases. Carnosine (ß-alanylhistidine). A dipeptide whose effect on the body is very diverse, as research in recent years has shown. The most important effects can be divided into two groups: firstly, carnosine works as a buffer for hydrogen ions and metals of variable activity, that is, it maintains their concentration at the desired physiological level. Secondly, the substance can have an antioxidant effect and stabilize cellular structures. Selenium. The trace element in the AndroDoz dietary supplement is included in an activated methylated form. It occupies a special place among the microelements necessary for the functioning of the body, participating in the life process from conception to old age. As modern research shows, selenium deficiency is found in most modern people, which leads to the development of various ailments. Selenium protects protein structures from endogenous oxidants, takes part in regulating the deception of vitamins E and A, reducing their breakdown. Most (up to 70%) selenium in the human body is found in amino acids and proteins, much less in lipids, and the rest is selenium in a free, inorganic state. Domestic and foreign scientific research proves that selenium deficiency must be replenished in order to avoid the development of severe functional disorders in the body. Licorice is a plant of the Glycyrrhizaglabra family of legumes (Fabaceae). In the rhizomes and roots of the plant there is a high concentration of substances such as triterpene saponin (containing glycyrrhizin up to 23%), flavonoids, polysaccharides (including up to 27% pectin and starch), and so on. Licorice is widely used in urological clinical practice, used to treat prostate adenoma, sexual dysfunction, prostatitis and chronic adrenal insufficiency, as well as to provide a tonic effect. Zinc, the AndroDoz dietary supplement contains an activated form. Aspartate, gluconate, picolinate and other zinc compounds are widely used in endocrinology and dermatology, in the fight against immunodeficiency conditions. Zinc has been found to be vital for male reproduction; with its deficiency, testosterone levels decrease and pathozoospermia develops. On the other hand, clinical studies have confirmed the beneficial effect of zinc on sperm maturation, including increasing the concentration, motility and number of normal morphological forms of sperm. Vitamins E and A, tocopherols. The antioxidant properties of these vitamins are well known. Thus, clinical tests have established that if a man takes vitamin E, the level of oxidative stress in the testicular tissue decreases, and sperm motility and their ability to penetrate the uterus increases. Vitamin A, like carotenoids close to it in structure, also play an important protective role, protecting cell membranes from oxidation. According to research, there is a positive correlation between the level of sperm motility and the level of vitamin A in the body, as well as between the concentration of sperm in men and a diet rich in carotenoids. In addition, vitamin A interacts with zinc: the substances mutually enhance antioxidant properties.

AndroDoz, indications for use Treatment of male subfertility, improvement of the quality and fertilizing ability of sperm, increases cryotolerance of sperm, indispensable before IVF ICSI procedures.

Contraindications Individual intolerance to the components of AndroDoz dietary supplement.

Method of administration and dosage: Adults (men) take 4 capsules per day with meals, duration of administration is 1 month, after a 2-week break, the dose can be repeated. It is recommended to consult a doctor before use.

Storage conditions: In a dry place, protected from light, at a temperature not exceeding 25 °C.

Shelf life: 2 years.