Aquadetrim: side effects, how to take

Contraindications

There are several contraindications to the use of pharmaceuticals:

Kidney failure
Hypercalcemia
Hypervitaminosis D
Sarcoidosis
Urolithiasis disease
Less than 1 month old
Kidney diseases
Urolithiasis disease
Hypersensitivity to the constituent drugs
Tuberculosis

The drug is prescribed with caution:

Bedridden patients
During pregnancy and breastfeeding
If a person uses cardiac glycosides
Children who were born with a small crown size

Side effects

With an excess of vitamin D, the following negative manifestations are observed:

Loss of appetite
Nausea
Constipation
Dry mouth
Polyuria
Sleep problems
Weight loss
Renal or vascular calcification
Increase in body temperature
Weakness
Polyuria
Mental disorders

If any of the signs of hypervitaminosis D appear, you should stop taking the medication. Try to reduce the intake of calcium in the body and start taking vitamins A, C, and B.

In some people, taking vitamin D3 leads to allergic reactions.

Note!

Description of the drug Aquadetrim vitamin D-3 solution aq. d/oral. approx. fl. 10ml on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.

Instructions for use of Aquadetrim

The instructions indicate that the dosage for each must be selected individually, taking into account the person’s diet.

Before use, the product must be dissolved in 1 spoon of water.

For preventive purposes, doctors prescribe 1 or 2 drops of the drug per day to children over 1 month old. Premature babies in difficult living conditions are recommended to take 3 drops per day.

In summer, it is advisable to reduce the dosage to 1 drop.

When treating rickets, up to 10 drops of vitamin are prescribed per day, the duration of therapy is determined by the doctor. In this case, the doctor must monitor blood counts and the patient’s condition. Treatment of rickets begins with 4 drops for 5 days; if a person tolerates them well, the dosage is increased to 6 drops. 10 drops of the medication are prescribed for very noticeable changes in bone tissue.

For rickets-like pathologies, 40-60 drops of the drug can be prescribed daily.

Aquadetrim (Vitamin D3) bottle 10ml

Indications

Prevention and treatment of vitamin D deficiency. Prevention and treatment of rickets, rickets-like diseases, hypocalcemic tetany, osteomalacia and metabolic-based bone diseases (such as hypoparathyroidism and pseudohypoparathyroidism). In the complex treatment of osteoporosis, including postmenopausal.

Directions for use and doses

Orally.
Dissolve Aquadetrim in 1 spoon of liquid. 1 drop contains about 500 IU of vitamin D3. Unless the doctor prescribes otherwise, the drug is used in the following dosages: Prophylactic doses:

full-term newborns from 4 weeks of life, up to 2-3 years with proper care and sufficient exposure to fresh air: 500-1000 ME (1 drop) per day;
premature babies, from 4 weeks of life, twins, infants in poor living conditions: 1000-1500 (2-3 drops) per day. In the summer, you can limit the dose to 500 IU (1 drop) per day.
pregnant women: a daily dose of 500 IU of vitamin D3 for the entire period of pregnancy, or taking 1000 IU / day, starting from the 28th week of pregnancy.
in the postmenopausal period 500-1000 IU (1-2 drops) per day.

Therapeutic doses:

for rickets: daily 2000 - 5000 IU (4-10 drops), depending on the severity of rickets (I, II or III) and the course of the disease, for 4-6 weeks, under careful monitoring of the clinical condition and the study of biochemical parameters ( calcium, phosphorus, alkaline phosphatase) blood and urine. You should start with 2000 IU for 3-5 days. Then, if well tolerated, the dose is increased to an individual therapeutic dose (most often 3000 IU). A dose of 5000 IU is prescribed only for pronounced bone changes. If necessary, after a one-week break, you can repeat the course of treatment. Treatment is carried out until a clear therapeutic effect is obtained, followed by a transition to a prophylactic dose of 500 - 1500 IU/day.
in the treatment of rickets-like diseases: 20,000-30,000 ME per day (40-60 drops), depending on age, body weight and severity of the disease, under the control of biochemical blood parameters and urine analysis. The course of treatment is 4-6 weeks. Treatment is carried out under the supervision of a doctor.
for complex treatment of postmenopausal osteoporosis: 500-1000 ME (1-2 drops) per day.

The dosage is usually prescribed based on the amount of vitamin D obtained from food.

special instructions

Avoid overdose. Individual provision of a specific need must take into account all possible sources of this vitamin. Too high doses of Aquadetrim used over a long period of time or shock doses can cause chronic hypervitaminosis D3. The determination of a child’s daily need for vitamin D and the method of its use should be determined by a doctor individually and each time subject to correction during periodic examinations, especially in the first months of life. Do not use high doses of calcium simultaneously with Aquadetrim. During treatment, periodic monitoring of the concentration of calcium and phosphate in the blood and urine is necessary.

Compound

1 ml of solution (30 drops) contains Colecalciferol (Vitamin D3) - 15,000 IU excipients: macrogol glyceryl ricinoleate, sucrose, sodium hydrogen phosphate dodecahydrate, citric acid monohydrate, anise flavor (or anise essence), gasoline alcohol, purified water.

Contraindications

Hypersensitivity to the components of the drug, especially to gasoline alcohol.
Hypervitaminosis D, increased concentration of calcium in the blood (hypercalcemia), increased excretion of calcium in the urine (hypercalciuria), urolithiasis (formation of calcium oxalate stones), sarcoidosis, acute and chronic diseases of the liver and kidneys, renal failure, active form of pulmonary tuberculosis. Children up to 4 weeks of age. With caution: state of immobilization, when taking thiazides, cardiac glycosides (especially digitalis glycosides); during pregnancy and breastfeeding. In infants with a predisposition to early overgrowth of fontanelles (when the size of the anterior crown is small from birth).

Use during pregnancy and breastfeeding

During pregnancy, Aquadetrim should not be used in high doses due to the possibility of a teratogenic effect in case of overdose. Aquadetrim should be prescribed with caution to women who are breastfeeding - the drug taken in high doses by the mother can cause overdose symptoms in the child. During pregnancy and breastfeeding, the dose of vitamin D3 should not exceed 600 IU per day

Side effects

Hypersensitivity to the components of the drug, hypervitaminosis D (symptoms of hypervitaminosis: loss of appetite, nausea, vomiting; headaches, muscle and joint pain; constipation; dry mouth; polyuria; weakness; mental disorders, including depression; weight loss; disorder sleep; increased temperature; protein, leukocytes, hyaline casts appear in the urine; increased calcium levels in the blood and its excretion in the urine; possible calcification of the kidneys, blood vessels, lungs). If signs of hypervitaminosis D appear, it is necessary to discontinue the drug, limit the intake of calcium, and prescribe vitamins A, C and B.

Overdose

Symptoms: loss of appetite, nausea, vomiting, constipation, anxiety, thirst, polyurades, diarrhea, intestinal colic.
Frequent symptoms are headache, muscle and joint pain, mental disorders, including depression, stupor, ataxia and progressive weight loss. Renal dysfunction develops with albinuria, erythrocyturia and polyuria, increased potassium loss, hyposthenuria, nocturia and increased blood pressure. In severe cases, clouding of the cornea may occur, less commonly swelling of the optic nerve papilla, inflammation of the iris, and even the development of cataracts. Kidney stones may form and calcification of soft tissues, including blood vessels, heart, lungs and skin, occurs. Cholestatic jaundice rarely develops.

Treatment: Stop using Aquadetrim. Contact your doctor. Take plenty of fluids. If necessary, hospitalization may be required.

Storage conditions

Store at temperatures from 5 C to 25 C. Protect from light. Keep out of the reach of children.

Best before date

3 years.

pharmachologic effect

Aquadetrim - Vitamin D3 - regulator of calcium-phosphorus metabolism. It is an active antirachitic factor. The most important function of vitamin D3 is to regulate calcium and phosphate metabolism, which promotes proper mineralization and skeletal growth.

Vitamin D3 is a natural form of vitamin D that is formed in humans in the skin under the influence of sunlight. Compared to vitamin D2, it is characterized by 25% higher activity. Colecalciferol plays a significant role in the absorption of calcium and phosphates from the intestine, in the transport of mineral salts and in the process of calcification of kosgei, and also regulates the excretion of calcium and phosphates by the kidneys. The concentration of calcium ions in the blood determines the maintenance of muscle tone of skeletal muscles, myocardial function, promotes nervous stimulation, and regulates the process of blood clotting. Vitamin D is necessary for the normal function of the parathyroid glands and is also involved in the functioning of the immune system, influencing the production of lymphokines.

Lack of vitamin D in food, impaired absorption, calcium deficiency, as well as insufficient exposure to sunlight, during the period of intensive growth of the child, leads to rickets, and in adults to osteomalacia; Pregnant women may experience symptoms of tetany, disruption of the processes of bone tissue formation in newborns. An increased need for vitamin D occurs in women during menopause, as they often develop osteoporosis due to hormonal imbalances.

Drug interactions

Antiepileptic drugs, rifampicin, cholestyramine reduce the reabsorption of vitamin D3. Use simultaneously with thiazide diuretics increases the risk of hypercalcemia. Simultaneous use with cardiac glycosides may enhance their toxic effect (increases the risk of heart rhythm disturbances).

How to take Aquadetrim for adults

Aquadetrim can be taken with or after meals.
The dosage of the drug directly depends on what goal you are pursuing.
To prevent vitamin D deficiency, adults only need to take 1 drop of the vitamin daily.
If malabsorption syndrome occurs, you must take 6 to 10 drops.
It is important to understand that both adults and children should take vitamin D for preventive purposes.
During pregnancy, you can also take Aquadetrim; it is better to check the dosage with your doctor. But usually at the beginning of pregnancy they drink 1 drop of Aquadetrim, and starting from the 7th month, the dosage is increased to 2 drops.

An overdose will have a negative impact on the intrauterine fetus.