Beneficial bacteria constantly live inside the vagina, which form the internal environment and provide local immunity. Under the influence of infectious processes, hormonal imbalances, as well as after childbirth or operations, the use of antibiotics, the microflora is disrupted. Balance can be restored in a few days or weeks. One of the effective remedies is Acylact suppositories.
Composition and description of the drug "Acilact"
"Acylact" is a drug that is available in the form of powder, lyophilisate, tablets and vaginal suppositories. The composition includes live bacteria - lactobacilli acidophilus and additional (auxiliary) components.
The product has a probiotic effect. It normalizes the vital activity of bacterial colonies that constantly live in the female genitalia, ensures normal metabolism of glycogen with the formation of the final product - lactic acid.
The drug also allows you to normalize the acidity level (pH) of the internal environment of the genital organs. The action of lactobacilli leads to a decrease in pH - the environment becomes acidic, which leads to the death of pathogenic bacteria. Thanks to this, local immunity increases, the body better resists infections.
Important!
Candles should be stored in the refrigerator at a temperature range of 2-10 degrees. Access for children is prohibited. The shelf life is 1 year - the drug cannot be used after this time.
Femilex candles: composition
Femilex is a vaginal suppository. They are elongated in shape, with rounded edges. The color of the suppositories is white, a yellowish tint is allowed. There may be a cavity in the form of an air rod inside each dose.
The action of the drug is based on lactic acid. 1 dose contains 100 mg of active substance. Macrogol acts as an additional component.
One cardboard package can contain 5 or 10 candles.
"Acilact" suppositories: indications for use
Vaginal suppositories are used as a primary or additional means of therapy to treat a number of pathologies:
- gynecological diseases that are accompanied by disturbances in the microflora of the female genitalia;
- vaginal dysbiosis;
- nonspecific colpitis;
- inflammatory pathologies of the genital organs in subacute and chronic forms;
- colpitis is atrophic and hormone-dependent.
The product is also used to prevent dysbacteriosis and complications of infectious processes during operations or childbirth.
ENZYME
Trade name: Acylact;
International nonproprietary name: Lactobacillus acidophilus;
Dosage form: vaginal suppositories.
Acylact, vaginal suppositories is a microbial mass of living, antagonistically active acidophilic lactobacilli of the Lactobacillus acidophilus 100ash, NK1, K3Sh24 strains, freeze-dried in a cultivation medium with the addition of a protective sucrose-gelatin-milk medium and formed into medical suppositories.
Composition: One suppository contains at least 107 live acidophilic lactobacilli (1 dose), excipients: solid petroleum paraffin, T-2 emulsifier, solid fat. Suppository weight - 1.3 g.
Description: Suppositories are yellowish-gray or light beige in color, torpedo-shaped. Inhomogeneity of color in the form of inclusions or marbling is allowed.
Biological and immunological properties: Live lactobacilli acidophilus have high antagonistic activity against pathogenic and opportunistic microbes, including staphylococci, enteropathogenic Escherichia coli, Proteus, which determines the normalizing effect of the drug in disorders of bacteriocenosis of the female genitalia. Lactobacilli metabilize glycogen in the vaginal epithelium to lactic acid, which maintains the vaginal pH at 3.8-4.02. A high concentration of lactic acid creates unfavorable conditions for the life of acid-sensitive pathogenic and opportunistic bacteria. By acidifying the genital mucosa, lactobacilli participate in the formation of an environmental barrier and ensure resistance of the genital mucosa to foreign microflora.
INDICATIONS FOR USE:
Treatment of adult patients with vaginal dysbiosis and nonspecific inflammatory processes of the vagina.
nonspecific colpitis (not associated with gonococcal, trichomonas, candidiasis and other specific infections). Prescribed as an independent remedy or after completing a course of antibacterial therapy;
vaginal dysbiosis, including bacterial vaginosis (gardnerellosis). Prescribed as an independent remedy or in complex therapy;
subacute and chronic stages of inflammatory processes in the female genital area. Prescribed after completion of a course of antibacterial therapy for the purpose of rehabilitation;
hormonally dependent senile and other colpitis. Prescribed as an independent remedy against the background of specific hormonal therapy;
preparation for planned gynecological operations in order to prevent postoperative complications;
prenatal preparation of pregnant women at risk for the development of inflammatory diseases for the purpose of prevention and treatment of vaginal dysbacteriosis;
as an adjuvant in the treatment of sexually transmitted diseases: gonorrhea, urogenital chlamydia, urogenital herpes, etc. The drug is used to restore normal microflora and colonization of the vagina with lactobacilli in combination and after specific antimicrobial, antiviral and immunomodulatory therapy. The combined use of suppositories and oral forms of acylact is recommended.
CONTRAINDICATIONS AND SIDE EFFECTS:
- It is not recommended for use for vulvovaginal candidiasis.
- No side effects were identified.
METHOD OF APPLICATION AND DOSAGE:
Before intravaginal administration, remove the packaging from the suppository.
Dysbacteriosis of the vagina:
- 1 suppository 2 times a day for 5-10 days.
Hydrogen cyanide vaginitis of hormonal nature:
- 1 suppository 2 times a day for 5-10 days.
In case of violation of the purity of vaginal secretions in pregnant women up to the III-IV degree:
- 1 suppository 1-2 times a day for 5-10 days or more, under the control of restoration of the purity of vaginal secretions to the I-II degree and the disappearance of clinical symptoms.
Prevention of purulent-septic complications during planned gynecological operations:
- 1 suppository 1-2 times a day for 10 days. If necessary, the course is repeated for 3-4 months with an interval of 10-20 days.
INTERACTIONS WITH OTHER MEDICINES:
The use of suppositories can be combined with the simultaneous administration of antibacterial, antiviral and immunomodulatory drugs. However, it is not recommended to combine it with simultaneous local administration of antibacterial drugs.
RELEASE FORM:
5 suppositories in a blister pack. 2 packages in a cardboard box with instructions for use.
CONDITIONS FOR DISCHARGE FROM PHARMACIES:
Dispensed without a doctor's prescription.
BEST BEFORE DATE:
1 year.
The drug is not suitable for use:
A drug whose packaging has been damaged.
The drug is not labeled.
A drug with altered physical properties (change in color, appearance of a rancid odor).
The drug has expired.
STORAGE AND TRANSPORTATION:
Store out of the reach of children at a temperature of 2 to 8°C
Transport at temperatures from 2 to 8°C
Contraindications and side effects
There are not many contraindications for use. The product should not be used if you have diagnosed vaginal candidiasis. In these cases, a separate course of treatment is first carried out, after which the doctor may prescribe Acylact suppositories to restore normal vaginal microflora.
Also, the drug is not used in the presence of individual intolerance to the active or auxiliary components. If allergic reactions occur, treatment is stopped. It is recommended to consult a doctor - you may need to change therapy.
No side effects have been reported to date. Suppositories are safe when used in certain dosages specified in the instructions. No cases of overdose have been identified either.
Instructions for medical use of the drug Femilex®
Trade name of the drug:
Femilex®
International nonproprietary or chemical name:
lactic acid
Dosage form:
vaginal suppositories
Compound:
One suppository contains: active ingredient: lactic acid – 100 mg; excipients: macrogol mixture: macrogol 1500 – (92–98)%, macrogol 400 – (8–2)%.
Description:
Suppositories are torpedo-shaped, white or white with a yellowish tint. Marbling and the presence of an air core and a funnel-shaped depression on the cut are allowed.
Pharmacotherapeutic group:
antiseptic
ATX code:
G01AD01
pharmachologic effect
Pharmacodynamics
Lactic acid is a natural waste product of lactic acid bacteria in the vagina and provides a pH of vaginal secretions in the range of 3.5-4.5. Suppositories with lactic acid help restore and maintain normal pH and vaginal flora, suppress the growth of acid-sensitive pathogenic and conditionally pathogenic flora. Lactic acid creates an acid reserve to correct the pH shift to the alkaline side observed during vaginal infections. Helps enhance the vagina's natural protection against genital infections.
Pharmacokinetics
There is no information on pharmacokinetics.
Indications for use
Normalization of disturbed microflora and vaginal pH, including bacterial vaginosis (as part of complex therapy).
Contraindications
Hypersensitivity to the components of the drug, vulvovaginal candidiasis, children (up to 18 years).
Use during pregnancy and breastfeeding
No special studies of the drug Femilex® have been conducted during pregnancy and breastfeeding. In animal studies, there was no evidence of toxic effects of lactic acid on the fetus. In clinical studies of lactic acid in various dosage forms for intravaginal administration, no safety problems were identified. Considering the fact that lactic acid is an intermediate product of mammalian metabolism and is normally found in the human body, including in amniotic fluid and breast milk, the use of Femilex® during pregnancy and breastfeeding is possible after assessing the potential benefits for the mother and risk to the fetus and breastfed infant. Before use, you should consult your doctor.
Directions for use and doses
Intravaginally. Before use, the suppository is released from the contour packaging. One vaginal suppository is inserted into the vagina (lying on your back with slightly bent legs) once a day. The course of treatment is 10 days. If there is no improvement after treatment or new symptoms appear, you should consult your doctor. Use the drug only according to the indications, method of administration and in the doses indicated in the instructions.
Side effect
Allergic reactions, itching, and in isolated cases, burning in the vagina, which disappear after discontinuation of the drug, are possible. If any of the side effects indicated in the instructions worsen or other side effects not listed in the instructions are noted, you should immediately consult a doctor.
Overdose
No cases of drug overdose have been reported.
Interaction with other drugs
No information available.
special instructions
If burning and itching occurs, it is recommended to conduct an examination to exclude a fungal infection of the vagina.
Impact on the ability to drive vehicles and machinery
Does not affect.
Release form
Vaginal suppositories 100 mg. 5 suppositories in a blister pack made of polyvinyl chloride film laminated with polyethylene. 1 or 2 blisters along with instructions for medical use of the medicinal product in a cardboard pack.
Storage conditions
At a temperature not higher than 25°C. Keep out of the reach of children.
Best before date
5 years. Do not use after expiration date.
Vacation conditions
Available without a prescription.
Manufacturer/organization accepting claims:
JSC "NIZHFARM", Russia 603950, Nizhny Novgorod, st. Salganskaya, 7 Tel. Fax E-mail:
Instructions for use of "Acilact" suppositories
Suppositories are used intravaginally, i.e. inserted directly into the vagina. The instructions are:
- Rinse the genitals thoroughly.
- Wash your hands with soap and dry.
- Remove the packaging from the suppository (only before administration).
- Lie on your back and insert the suppository as deeply as possible.
Take 1 or 2 suppositories per day, and the duration is 10 days. Then a break is taken for 10 or 20 days, after which the cycle is repeated if necessary. It is recommended to discuss the dosage and duration of therapy with your doctor.
Femilex candles: instructions
Treatment of vaginal candidiasis, vulvovaginitis and other inflammatory processes is carried out according to the following scheme: 1 suppository is administered intravaginally, mainly at night.
The dose is removed from the package, placed in a supine position with knees bent and injected as deeply as possible into the vagina. It is recommended to use suppositories immediately before bedtime, because after administration the thick consistency of the suppositories becomes liquid. If the body is in an upright position, the medicine will easily leak out, which is why the expected therapeutic effect will not be achieved.
During night sleep, the product will have the opportunity to be evenly distributed in the vaginal cavity and increase the acidity of the environment to natural values. The next morning, the liquid will flow out after the candle dissolves. Do not confuse it with discharge and look for pathological causes.
The normal vaginal fluid range is 3.5-4.5 units. Already from the first application the required value will be achieved. For mild urogenital infections, a 5-day course is sufficient. If a woman suffers from relapses of the disease, she will need to buy a package of Femilex containing 10 pieces and continue treatment for 10 days.
Femilex during pregnancy
Due to the fact that there has not been a sufficient number of studies on the use of the drug in pregnant women, it is impossible to say unequivocally about the safety of suppositories. Based only on scientific works devoted to the study of the effect of lactic acid on the fetus in animals, it can be stated that no pathologies have been recorded.
At the same time, medical science has proven that lactic acid is a natural metabolite that is normally present in the human body, including in amniotic fluid. Therefore, there is no prohibition on the use of Femilex for pregnant women. But before starting treatment, you need to consult a specialist and choose the required course.
Femilex supp vag 100 mg pack cont cell/pack card x10
Pharmacological action Lactic acid is a natural product of the life activity of lactic acid bacteria in the vagina, providing a pH of vaginal secretion in the range of 3.5-4.5. Suppositories with lactic acid help restore and maintain normal pH and vaginal flora, suppress the growth of acid-sensitive pathogenic and conditionally pathogenic flora.
Lactic acid creates an acid reserve to correct the pH shift to the alkaline side observed during vaginal infections. Helps enhance the vagina's natural protection against genital infections.
Pharmacokinetics No information is available on pharmacokinetics.
Indications for use of the drug FEMILEX® are normalization of disturbed microflora and vaginal pH, including bacterial vaginosis (as part of complex therapy).
Dosage regimen Intravaginal. Before use, the suppository is released from the contour packaging. One vaginal suppository is inserted into the vagina (lying on your back with slightly bent legs) once a day. The course of treatment is 10 days.
Side effects Possible allergic reactions, itching, and in isolated cases, burning in the vagina, which disappear after discontinuation of the drug.
Contraindications to the use of the drug FEMILEX®: hypersensitivity to the components of the drug, vulvovaginal candidiasis, pregnancy and breastfeeding, children under 18 years of age.
Use of the drug FEMILEX® during pregnancy and breastfeeding Use during pregnancy and breastfeeding is contraindicated, since clinical studies have not been conducted in pregnant women. There is no information about penetration into breast milk.
Use in children Contraindicated in children under 18 years of age.
Special instructions If burning and itching occurs, it is recommended to conduct an examination to exclude a fungal infection of the vagina.
Overdose No cases of drug overdose have been reported.
Drug interactions No information available.
Conditions for dispensing from pharmacies By prescription.
Storage conditions and periods At a temperature not exceeding 25°C. Keep out of the reach of children. Shelf life: 2 years.
Release form, composition and packaging
Vaginal suppositories are white or white with a yellowish tint, torpedo-shaped, marbling of the surface is allowed.
1 sup. lactic acid 100 mg
Excipients: base for suppositories - sufficient quantity to obtain a suppository weighing 3 g (macrogol 1500 (polyethylene oxide 1500) - 92-98%, macrogol 400 (polyethylene oxide 400) - 8-2%).
5 - contour cell packaging (1) - cardboard packs. 5 - contour cell packaging (2) - cardboard packs.
Clinical and pharmacological group: A drug that regulates the balance of vaginal microflora
Registration No.:
•sup. vaginal 100 mg: 5 or 10 - LP-001689, 05/03/12. Active.
