Pharmacodynamics and pharmacokinetics
Multicomponent product.
Acetylsalicylic acid has an antipyretic and anti-inflammatory effect, reduces pain, and also moderately suppresses platelet and thrombus formation processes, improves perfusion at the site of inflammation.
Paracetamol has an analgesic, antipyretic and weak anti-inflammatory effect, which is associated with its effect on the thermoregulation center and a weak ability to suppress the biosynthesis of prostaglandins.
Caffeine increases the excitability of the spinal cord, vasomotor and respiratory centers, dilates the kidneys, blood vessels of the muscles, brain, heart, and reduces platelet aggregation; reduces the feeling of fatigue, drowsiness , increases performance.
In this combination, it has almost no stimulating effect on the brain, but helps regulate cerebral vascular tone and accelerate perfusion.
What does Askofen help with?
The composition of this medicine is similar to Citramon, only different proportions are used. The drug helps relieve pain, inflammation, and it also normalizes the temperature if it is elevated. Due to the fact that it contains caffeine, the effect of which is described above, the excitability of the central nervous system increases, fatigue goes away to some extent, and the person becomes more active. Askofen increases blood pressure if it is low. It should be taken for hypotension in the amount of 2 tablets, but it does not help everyone, and its effect is short-lived (relates to increasing blood pressure). Continuous use of the drug is not recommended.
Contraindications
- Lesions of the digestive tract of an erosive-ulcerative nature.
- "Aspirin" asthma.
- Hypersensitivity.
- Bleeding from the digestive organs.
- Hemophilia.
- Hypoprothrombinemia.
- Vitamin deficiency K.
- Pregnancy or lactation .
- Severe coronary heart disease.
- Kidney failure.
- Lack of glucose-6-phosphate dehydrogenase.
- Severe arterial hypertension.
- Glaucoma.
- Sleep disorders.
- Portal hypertension.
- Surgical interventions with expected bleeding.
- Increased excitability.
- Hemorrhagic diathesis.
- Age up to 15 years.
It is recommended to take Coficil-Plus with caution if you have gout or liver disease.
Does pu-erh increase blood pressure?
Pu-erh is a dark variety of tea, but not black, as the manufacturing technology is different. Budget options for this tea are ready-made Pu-erh (Shu) and raw Pu-erh (Shen). At reduced pressure, the second of them is used. Thanks to it, the body’s tissues receive more nutrition, and digestion is normalized to some extent.
Shu Pu'er should not be drunk in large quantities. It lowers cholesterol in the blood, is used to prevent vascular and heart diseases, and removes harmful substances and toxins from the body. Pu-erh increases blood pressure, so if the norm is exceeded, short-term hypertension may occur. To avoid affecting blood pressure, drink it not so strong or in the amount of 1-2 cups per day. It is better to avoid consumption at night.
Side effects
Nausea, gastralgia, hepatotoxicity , vomiting, erosive-ulcerative lesions of the digestive system, tachycardia , allergic reactions , nephrotoxicity , increased blood pressure , bronchospasm.
dizziness , tinnitus, weakened platelet aggregation, hypocoagulation, deafness, headache , Reye's syndrome , hemorrhagic syndrome are possible .
Propolis - for blood pressure?
Propolis is produced by bees from resinous substances collected from plants. This is a useful substance that has antiviral, antibacterial, anti-inflammatory effects, etc. Propolis helps relieve fatigue and increase activity.
Researchers from Bulgaria wondered about the effect of propolis on human blood pressure. The experiment involved people with hypertension who were diagnosed with this disease 4-5 years ago. They were placed in a hospital, where they must remain without taking medications that affect blood pressure. Next, propolis (30% alcohol solution) was prescribed for treatment. It was given to patients 40 drops 3 times a day, an hour before meals. After the experiment, the patients experienced symptoms such as headaches, no more noise in their ears, no more heart problems, etc. In ¾ of the patients, the blood pressure returned to normal. But in one quarter of the subjects, blood pressure remained at approximately the same level as before the start of the tests. From this they conclude that propolis reduces blood pressure.
Instructions for use Coficil-Plus (Method and dosage)
Instructions for use Coficil-Plus prescribes taking the drug orally, during or after meals, 1 tablet every four hours; for pain, take 1-2 tablets; the usual daily dose is 3-4 tablets, the highest daily dose is 8 tablets. The duration of therapy should not exceed 7-10 days.
The medicine should not be taken for more than five days as an analgesic and for more than three days as an antipyretic. Other dosages and patterns of use are determined by the doctor.
Non-drug treatments for hypotension
It is possible to increase blood pressure without medications to some extent, and this measure is purely individual. It is important to walk in the fresh air more often, at least an hour a day, and for pregnant women - at least an hour in the morning/afternoon and an hour in the evening. Sports or physical activity stimulates blood circulation, and accordingly, blood pressure normalizes. Although it is known that professional athletes have slightly lower blood pressure levels than other people.
If you notice problems with blood pressure, it will be useful to take a contrast shower in the morning (alternate cold and hot water). This procedure has its own characteristics, which we will not describe here. To normalize blood pressure, proper nutrition is important. During fasting, the body begins to save resources, temperature and pressure decrease. Sleep should be at least 8 hours a day for teenagers and adults. You should also avoid overwork, both mental and physical equally. Alternate mental and physical activities.
Overdose
Signs of overdose: nausea, ringing in the ears, gastralgia, vomiting, dizziness, lethargy, collapse, drowsiness , bronchospasm , convulsions, difficulty breathing, anuria , respiratory acidosis , bleeding.
Treatment of overdose: monitoring pH balance and electrolyte balance; depending on the level of metabolism, the use of sodium citrate, sodium lactate or sodium bicarbonate is recommended.
Pentalgin - does it lower blood pressure?
This is a drug for pain, which contains naproxen, paracetamol, drotaverine, caffeine, pheniramine. If the pressure is normal or below normal, the values on the tonometer will not change when taking Pentalgin. Since the drug contains caffeine, the blood vessels may narrow, which means that the pressure will not increase by much. In severe hypertension, the drug is contraindicated.
Pentalgin increases blood pressure if taken in excess of the norm or for long courses. You can take no more than 4 tablets per day, and the duration of the course is a maximum of 5 days.
Interaction
Combined use with other anti-inflammatory non-steroidal drugs, Methotrexate increases the likelihood of developing undesirable effects.
Reduces the effectiveness of Spironolactone, Furosemide, antihypertensive and anti-gout drugs that promote the evacuation of uric acid.
Metoclopramide enhances the absorption of Paracetamol .
Salicylamide, barbiturates, Rifampicin, antiepileptic drugs and other inducers of microsomal oxidation enhance the synthesis of toxic derivatives of Paracetamol , which affect liver function.
The simultaneous use of Paracetamol and ethanol increases the risk of hepatotoxic effects.
Under the influence of Paracetamol, the half-life of Chloramphenicol is extended fivefold.
Caffeine enhances the absorption of ergotamine.
Does Ketorol increase blood pressure?
Ketorol relieves inflammation and pain. Refers to non-steroidal drugs. The active ingredient of this medicine is ketorolac. Ketorol is available in tablets and liquid for injection. When taking the medicine, a slight increase in blood pressure may occur. But this only happens if a person is prone to hypertension. Ketorol cannot be combined with drugs that lower blood pressure, as well as with diuretics, because taking Ketorol will reduce their effectiveness.
special instructions
With long-term use of the drug, monitoring of blood counts and liver condition is necessary.
Children are prohibited from being prescribed medications containing acetylsalicylic acid , since in case of infection they can increase the risk of Reye's syndrome ( encephalopathy , vomiting, hepatomegaly ).
Acetylsalicylic acid in small doses weakens the evacuation of uric acid.
Acetylsalicylic acid has a teratogenic effect.
Does creatine increase blood pressure?
Creatine is an amino acid that athletes take as a supplement. Creatine increases endurance and is used for more active muscle building. The feeling of fatigue when taking creatine becomes less, so workouts can be more intense, etc.
Creatine retains some fluid in the body, which is why it presumably increases blood pressure. But this only occurs in a small percentage of people. For others, urine output and blood pressure remain unchanged. To prevent blood pressure from increasing with constant use of creatine, it is better not to drink strong tea (including pu-erh) and coffee during this period.
Analogs
Level 4 ATC code matches:
Acetylsalicylic acid
Aspirin-S
Citropak
Aspirin
Citramon
Farmadol
Askofen-P
Cefekon N
Aquacitramon
Upsarin UPSA
Citrapack
Alca Prim
Thrombopol
Citrapar
Askofen-P, Aquacitramon, Acepar, Migrenol Extra, Acifein, Citramarin, Citramon Ultra, Citramon P, Citrapar, Excedrin.
Does Echinacea Increase Blood Pressure?
Echinacea is a natural herbal remedy. It is used mainly to relieve inflammation and strengthen the body's defenses. Also, medicines based on echinacea improve metabolic processes. If you use these medications for a long time or in large quantities, side effects may occur:
- excitability of the central nervous system
- irritability
- dizziness
- difficulty falling asleep
- increased blood pressure
Echinacea should not be prescribed to patients with collagenosis, blood diseases, autoimmune diseases, or to pregnant women. You can find out other contraindications from the instructions for a particular drug.
