Pimafucin cream: detailed instructions for use, what it helps with, analogues and reviews from women

Compound

The suppository contains natamycin as an active ingredient. Additional components include: cetyl alcohol , adipic acid , solid fat, sorbitan trioleate , polysorbate 80, sodium bicarbonate.
Pifamucin ointment. The main component is natamycin . Auxiliary components: propylene glycol, cetostearic alcohol, sodium lauryl sulfate, purified water, decyl letate, methyl parahydroxybenzoate, cetyl wax ether, propyl parahydroxybenzoate.

Pifamucin tablets. The active ingredient in the tablets is natamycin , auxiliary ingredients: kaolin, white beeswax, polyvinylpyrrolidone , titanium dioxide, sucrose, magnesium stearate, kaolin, methyl parahydroxybenzoate, gelatin, gum arabic, potato starch, calcium carbonate, lactose, triacetin.

Composition and release form

in bottles of 20 pcs.; 1 bottle in a box.

in blister-free packaging 3 pcs.; in a cardboard box 1 or 2 packages.

in tubes of 30 g, in a cardboard box 1 tube.

Pharmacodynamics and pharmacokinetics

The principle of action of the drug is based on the binding of sterols in the cell membrane, violating their integrity, which causes the death of the microorganism. The drug affects yeast-like fungi (especially Candida albicans), yeast , dermatophytes , pathogenic fungi .

Natamycin is active when used topically, has no systemic effect, and is not absorbed through mucous membranes or skin. The enteric coating of the tablets determines the effect of the drug in the intestines.

Manufacturer's instructions

The annotation states that the drug contains milk sugar and sucrose, which people with congenital diseases should pay attention to:

• with allergies to galactose, fructose;
• lactase deficiency;
• impaired absorption of glucose/galactose in the small intestine;
• combined deficiency of sucrase and isomaltase enzymes.

If the patient has at least one of the above pathologies, then he must warn the local doctor about the problem before starting therapeutic procedures. The specialist will assess the risks and search for a more suitable medicine that is similar in effect to the main one.

This dosage form of Pimafucin is not used in the treatment of infants due to the inability to swallow tablets normally. For children under one year of age, there are other forms and varieties of antifungal and antibacterial agents.

During therapy, the active components of the drug do not affect the rate of reactions. During therapy, it is allowed to drive vehicles and work with moving complex mechanisms.

There is no information about the possible interaction of alcohol with the medicine. The manufacturer does not recommend the consumption of alcoholic beverages during treatment procedures. During clinical studies, the interaction of the antibiotic with other medications was not recorded.

Indications for use

Pimafucin cream is prescribed for fungal infections of the nail plates, skin and mucous membranes, including vulvovaginitis , balanoposthitis , vulvitis , vaginitis , ringworm , otitis media caused by fungi or complicated by candidiasis, candidiasis of the nails and skin .

Pimafucin tablets are effective for fungal diseases of the external auditory canal, mucous membranes, and oral cavity. It is prescribed for intestinal candidiasis , after therapy with corticosteroids , antibiotics , cytostatics , vulvovaginitis , vulvitis , vaginitis , acute atrophic or pseudomembranous candidiasis with cachexia .

Pimafucin suppositories are prescribed for balanoposthitis , vulvovaginitis , vulvitis , vaginitis caused by Candida fungi.

What do Pimafucin suppositories help with?

Suppositories are prescribed for the treatment of vaginitis and vulvitis caused by fungal infections. The use of Pimafucin does not lead to a decrease in the sensitivity of pathogenic flora to the drug component. In medicine, there have been no cases of microorganism resistance to natamycin.

Pimafucin suppositories are a reliable medicine for candidiasis, which most often manifests itself as white copious discharge, burning and itching on the mucous membranes of the genital organs. To get rid of symptoms and completely cure candidiasis, it is enough to administer 1 suppository, preferably at night. This will allow the active substance to contact the affected mucosa for as long as possible, making the treatment more effective. Suppositories are a female dosage form.

Instructions for use of Pimafucin (Method and dosage)

Pimafucin suppositories, instructions for use. Used intravaginally. For vulvovaginitis , vulvitis and vaginitis , 1 suppository is administered for 3-6 days. It must be administered in the “lying down” position, as deeply as possible, before bedtime, once a day. If treatment of vaginitis does not help, then you should take tablets - 10-20 days, 1 tablet four times a day. For men, use cream during treatment. The duration of treatment is determined in each case individually. After the symptoms of the disease disappear, treatment should be continued for several more days.

Instructions for the cream. For external use. The ointment should be applied to the affected areas one to several times a day for balanoposthitis , vulvovaginitis and vulvitis . If symptoms persist, suppositories or tablets are prescribed. For dermatomycosis (including diaper rash in children and candidiasis of the nails and skin), the suspension should be applied to the nails and skin up to 4 times a day.

For mycosis of the external auditory canal, the affected area should be lubricated with cream up to four times a day, after cleaning the ear. After use, it is necessary to place a turunda made of cotton or wool into the ear canal. The duration of treatment is determined individually. After the symptoms completely disappear, it is necessary to continue treatment for several days.

Instructions for use of tablets. For intestinal candidiasis, are prescribed 1 tablet four times a day, children - 1 tablet twice a day. On average, the course of treatment lasts a week.

Description of the drug

Pimafucin cream is a white product with a yellowish tint with a thick consistency and no characteristic odor. It is intended for the treatment of pathologies caused by yeast-like fungi. These microorganisms belong to opportunistic microflora and do not show themselves for a long time. But with a sharp decrease in immunity, fungi rapidly become more active.

Clinical manifestations of infection include sticking in the corners of the mouth and cheesy discharge from the urethra or vagina. Red spots on the skin indicate a mycotic lesion. All diseases are dangerous, contagious, and require immediate medical intervention. Antifungal drugs are used in therapy, including Pimafucin ointment.

What is the topical application prescribed for:

• mycotic lesions of the skin and mucous membranes;
• fungal infection of the nail plates on the hands and feet;
• bacterial pathologies of the ear, complicated by an associated mycotic infection;
• vaginal candidiasis.

The cream works effectively after the first application to pathological lesions. It helps to quickly get rid of the symptoms of a fungal disease by destroying its pathogens.

When diagnosing an uncomplicated pathology, it is sufficient to use only the cream. When a recurrent disease is detected, other medications are included in the therapeutic regimen. Usually these are tablets of the same name and intravaginal suppositories.

Pimafucin helps well against vaginal candidiasis, but treatment is indicated for both sexual partners. Women are prescribed suppositories or cream, and men only cream.

Clinical and pharmacological group

The cream is an external agent from the clinical-pharmacological group of antimycotic drugs. The active ingredient is a polyene antifungal antibiotic, so Pimafucin can be classified as an antimicrobial agent.

pharmachologic effect

Low concentrations of natamycin have a fungistatic effect.
A polyene antibiotic from the macrolide group inhibits the growth and reproduction of pathogenic fungi. This property is often used for prophylactic purposes to prevent the spread of infection. Natamycin in high concentration exhibits powerful fungicidal activity. It prevents fungi from producing ergosterols, the structural elements of membranes. As a result, the integrity of the entire cell is disrupted, so it quickly collapses.

Pimafucin is a broad-spectrum antimycotic agent. It is active against the following fungal species:

• yeast-like fungi Candida - causative agents of oral candidiasis and thrush;
• dermatophytes that cause severe skin lesions.

Pimafucin is one of the few antimycotics that are used throughout treatment. The fact is that fungi are not capable of developing resistance to natamycin.

Release form and composition

The Pimafucin therapeutic line includes three of its dosage forms. This is a cream for application to the skin and mucous membranes, vaginal suppositories and tablets for oral administration. All drugs contain one active substance with pronounced antifungal activity - natamycin.

The Italian manufacturer packages the cream in a plastic or aluminum tube of 30 g. The secondary packaging for the drug is a yellow cardboard box with attached instructions for use.

In addition to natamycin, Pimafucin cream contains the following auxiliary components:

• macrogol;
• cetostearyl alcohol;
• sodium lauryl sulfate;
• distilled water;
• methylparaben;
• propylparaben;
• wax.

Additional ingredients ensure maximum absorption of the antibiotic into the mucous membranes and skin.

Many of them have weak antiseptic properties, which enhances the therapeutic effect of the drug. The components of the product form protective shells, preventing bacterial infection of tissues affected by inflammation.

Storage conditions and periods

The shelf life of the antimycotic drug is 24 months, after the seal of the tube is broken - 3-4 weeks. It should be stored at room temperature in a dark place out of reach of small children. Freezing Pimafucin cream is not allowed. If the consistency, color changes, or a rancid odor appears, the product is not suitable for treatment.

special instructions

Under the influence of body temperature, vaginal suppositories quickly dissolve, forming a foamy mass, due to which the active substance is distributed evenly. For recurrent or chronic infections, therapy can be supplemented with cream or tablets.

Cetyl alcohol, which is part of the suppositories, can cause a burning sensation in the genital area. Candle therapy should be interrupted during menstruation. During treatment with suppositories, sexual intercourse may not be excluded. However, both partners should be examined, and if a lesion is detected, Pimafucin cream for men should be used. Treatment with ointment for men occurs in the manner prescribed by the instructions. When having sexual intercourse during treatment, barrier contraceptives should be used.

It is possible to prescribe Pimafucin to newborns.

Side effect

Therapeutic manipulations can cause the appearance of non-standard responses of the body. Taking Pumafucin can provoke the appearance of:

• attacks of nausea;
• dyspeptic disorders with diarrhea.

Side effects occur on the first day of using the tablets and disappear spontaneously during treatment. If these symptoms or other reactions not described in the instructions occur, the patient should visit the attending physician and describe in detail the changes that have occurred in the general condition.

Pimafucin's analogs

Level 4 ATC code matches:
Colistin

Alpha Normix

Analogs of tablets: drugs Alpha Normix and Nystatin-Health .

Analogues in the form of suppositories: Nystatin , Livarol , Clotrimazole . The price of analog candles is from 37 to 320 rubles.

Pimafucin has a cheaper analogue - Nystatin , a domestically produced drug, similar in action.

Clotrimazole or Pimafucin - which is better?

Clotrimazole is available in the form of suppositories and cream. The course of treatment usually lasts about a week, the drug is well tolerated, which reduces the risk of side effects to a minimum. However, it may cause allergic reactions to any of its components. If the disease is detected in a woman, thrush ointment for men is used. According to experts, Pimafucin is more effective when used topically and it almost does not enter the systemic bloodstream. Therefore, it can also be used to treat pregnant women.

Which is better: Terzhinan or Pimafucin?

Terzhinan is produced in the form of vaginal tablets; it can be prescribed not only in the presence of the disease, but also for its prevention. The average duration of drug treatment is 10 days. It is also easily tolerated and can be used before childbirth.

What is more effective Pimafucin or Flucostat

The drug Flucostat is based on the active substance fluconazole, which is a fungicide, like natamycin Pimafucin. However, the difference between the drugs is significant in the mechanism of action. Flucostat is sold in capsule form for oral administration. Many may like the fact that just one capsule can relieve leucorrhoea and the discomfort associated with thrush, and taking the second capsule, as a rule, is a control.

In comparison with the six-day course of Pimafucin, this may seem like a plus, but not everyone can take advantage of this advantage. Once in the intestinal lumen, fluconazole is completely absorbed, and after a certain time it can be detected in all human biological fluids, including saliva. Therefore, its use during pregnancy and lactation, as well as in patients with renal and liver failure, is impossible.

Pimafucin during pregnancy and lactation

There are no contraindications for taking the drug for pregnant women or while breastfeeding. Tablets, creams and suppositories are used for thrush both in the early stages of pregnancy and in later stages. Most often, Pimafucin suppositories are prescribed during pregnancy, rather than other forms of this medicine. The drug is non-toxic and safe for the fetus both during the 1st trimester and 2nd trimester, as well as during lactation. However, to minimize the risk, it is better to take suppositories during lactation, or cream. Use of the drug is as indicated in the instructions.

In what cases can a doctor prescribe medication for a child?

The main range of use of the drug in children is thrush caused by pathogenic fungi of the genus Candida. These microorganisms constantly live in the human body and belong to opportunistic microflora. A child often becomes infected with them in the first days of life from his mother.

Fungi do not manifest themselves for a long time and do not have any adverse effects on the baby’s body. But with a sharp decrease in immunity or an unbalanced diet, Candida rapidly activates. Typically, fungi affect the skin and mucous membranes of the genital organs, causing redness and itching. Infants have many folds on their body, into which pathogenic microorganisms also penetrate.

Dermatologists prescribe Pimafucin when diagnosing the following symptoms:

• discharge of a cheesy mass from the urethra in boys, indicating the development of balanoposthitis;
• the appearance of thick whitish discharge in girls - the main sign of thrush, fungal vaginitis and vulvovaginitis.

These pathologies are always accompanied by burning, stinging and other uncomfortable sensations. The skin and mucous membranes of the genital organs look swollen, red and inflamed. Often pathological foci are localized in other parts of the epidermis. Doctors suspect a fungal skin infection when a small rash forms. If left untreated, blisters with liquid contents form on the child’s skin.

At what age is it allowed to take Pimafucin?

According to the instructions for use, Pimafucin ointment for children can be used from the first days of life. It does not contain aggressive chemical compounds that can harm the baby. Side effects are rare. As a rule, this happens when parents exceed dosages in the hope of speeding up recovery.

Treatment with cream always gives a quick positive result, so there is no need to violate the dosage regimen.

Redness and swelling of the skin often indicates the development of candidiasis. But using Pimafucin without a doctor’s prescription is strictly prohibited, and here’s why:

• clinical manifestations of fungal diseases are similar to the symptoms of bacterial infections;
• improper treatment will cause the pathology to progress and become chronic.

When diagnosing mild thrush, a dermatologist may include only antiseptics in the therapeutic regimen. Regular treatment of the skin with them and adherence to hygiene rules will allow you to do without antifungal agents. The Pimafucin therapeutic line also includes tablets and vaginal suppositories.

The tablet form is usually used in children from 3 years of age. The drug is enteric coated, so it cannot be crushed or dissolved in water. It is prescribed only if the child can swallow the whole tablet. Vaginal suppositories are rarely used in the treatment of children.

Reviews about Pimafucin

On the forums, the overwhelming majority of patients report a positive effect after using the medicine. However, there are cases when there is no improvement in the condition or it even worsens. There are also claims about the short-term effect of treatment for thrush and other diseases.

Pifamucin for thrush , according to patients, helps by quickly eliminating its symptoms. Moreover, the cream is effective for both women and men. Pimafucin tablets for thrush also help in the treatment and prevention of candidiasis.

Reviews about the tablets are most often good; patients write about the fast and effective action of the medicine and the complete absence of side effects. Reviews of Pimafucin suppositories for thrush report that they relieve itching faster than when taking tablets, as they act locally. There are no negative reviews about Pimafucin cream; it helps well with fungal diseases and is easily tolerated. Most often, the ointment is prescribed to men. Positive reviews during pregnancy note that the drug does not affect the development of the fetus and is very well tolerated, quickly eliminating the disease.

Reviews

Evgeniya, Kislovodsk

During pregnancy, she fell ill with bronchitis, and as a result, thrush developed. Before conception, I always used Pimafucin suppositories for insertion into the vagina. I asked the doctor if it was possible to use suppositories during pregnancy. The doctor recommended using a safer cream.

Valeria, Barnaul

As soon as I get a little cold, symptoms of thrush appear. Pimafucin cream helps a lot. Dry mucous membranes, pain and burning disappear after the first application of the drug. But I always use it for at least 5-7 days.

Pimafucin cream (review) from 250 rub.

Overall

4.4

• Efficiency
• Price
• Safety
• Availability

Pros

• Safety
• Efficiency
• Does not leave greasy stains

Cons

• Side effects
• Price
• Small volume

Pimafucin price, where to buy

The price of Pimafucin cream in Ukraine is 87 UAH, in particular in Kharkov the ointment costs about 81 UAH.

In Russia, the price of Pimafucin tablets is 360 rubles, in Belarus the cost of the medicine in tablets is 133.5 thousand rubles.

The price of Pimafucin suppositories for thrush is 270-380 rubles. In Odessa, candles No. 3 cost 123 UAH, candles No. 6 – 213 UAH.

You can find out how much the suppositories cost and buy other forms of the drug directly at the pharmacy.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Pimafucin vaginal suppositories.
  100 mg 3 pcs Temmler Italy S.r.L. RUB 257 order

Pharmacy Dialogue

• Pimafucin cream (tube 30g)Temmler

  RUB 493 order

• Pimafucin vaginal suppositories 100 mg No. 3Temmler

  RUB 257 order

• Pimafucin (tab. 100 mg No. 20) Yamanouchi

  RUB 684 order

• Pimafucin vaginal suppositories 100 mg No. 6 Temmler

  RUR 545 order

• Pimafucin (100 mg tablet No. 20)Astellas Pharma

  RUR 673 order

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Pharmacy24

• Pimafucin 100 mg No. 3 vaginal suppositories Temmler Italy S.r.l., Italy
  149 UAH.order
• Pimafucin 100 mg No. 6 suppositories Temmler Italy S.r.l., Italy

  287 UAH order

• Pimafucin 2% 30 g cream Temmler Italy S.r.l, Italy

  146 UAH order

• Pimafucin 100 mg N20 tablets Astellas Pharma Europe B.V., Netherlands

  431 UAH. order

PaniPharmacy

• Pimafucin suppository Pimafucin vaginal suppositories 100 mg No. 6 Italy, Temmler Italia

  296 UAH. order

• Pimafucin tablets Pimafucin film-coated tablets 100 mg No. 20 Netherlands, Astellas Pharma Europe

  489 UAH. order

• Pimafucin cream Pimafucin cream 2% 30g No. 1 Italy, Temmler Italia

  169 UAH order

• Pimafucin suppository Pimafucin vaginal suppositories 100 mg N3 Italy, Temmler Italia

  166 UAH order

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Standards for storage and sale

The drug is stored in dry, dark rooms at a temperature of up to 25 degrees. Tablets should be kept in a safe distance from children and pets. The medicine is valid for 4 years, after the expiration date written on the packaging, it is disposed of along with household waste.

You can buy Pimafucin at any of the available regular or online pharmacies. The average price for a medicine starts from 425 rubles, the final cost depends on the availability of discounts and promotions. Trading platforms deliver the drug to order.