A burning sensation, itching in the anal area and other unpleasant symptoms indicate the development of hemorrhoids. To treat it, as a rule, suppositories are used. Among the inexpensive but effective drugs is Anuzol. Many buyers note that the medicine gives results in the first days. At the same time, you can buy it at a price accessible to everyone.
Compound
One suppository includes active ingredients: 100 mg of xeroform , 20 mg of belladonna extract and 50 mg of zinc sulfate .
Additional ingredients: 11 mg polysorbate 80, 120 mg glycerol , 110 mg T2 emulsifier.
Solid fat is used as a base for suppositories, so that the weight of one suppository ranges from 2.09 to 2.31 grams.
Pharmacodynamics and pharmacokinetics
Anuzol suppositories, due to the effects of the active ingredients, are a complex-action drug aimed at the local treatment of hemorrhoids , anal fissures and other damage to the anorectal area .
Thanks to the dermatotropic and disinfectant properties of xeroform, the drug has a drying, antiseptic and astringent effect.
Zinc sulfate is also characterized by a drying effect in combination with a pronounced anti-inflammatory effect.
Belladonna (belladonna) affects the decrease in muscle tone of the gastrointestinal tract, which leads to increased sphincter tone , and its additional anticholinergic and antispasmodic effect helps prevent the stimulating effects of acetylcholine .
Pharmacodynamics
The product is used to treat hemorrhoids. Characterized by complex effects:
- antispasmodic (prevents spasms);
- antiseptic (disinfects);
- drying;
- anti-inflammatory;
- astringent.
Thanks to this, the drug is effective for the treatment of anal fissures, itching and other unpleasant consequences. Xeroform acts as an antiseptic and has an astringent and drying effect. It helps to cope with inflammatory processes due to disinfection.
Zinc sulfate also acts as a drying agent. It also has an anti-inflammatory effect. Belladonna extract (also called belladonna) enhances sphincter tone, blocks spasms, allows muscles to relax, and also contributes to the treatment of hemorrhoids.
Contraindications
suppositories for hemorrhoids should not be used:
- with hypersensitivity to any of the ingredients of the suppository;
- for heart failure during periods of exacerbation;
- with intestinal atony ;
- with myasthenia gravis ;
- with tachyarrhythmia ;
- for benign hyperplasia ;
- with closed-angle glaucoma ;
- during periods of breastfeeding and pregnancy .
Drug interactions and overdose
The drug can be taken with different drugs, but it should be borne in mind that the use of Anuzole can increase the effects of medications belonging to the following groups:
- antispasmodics;
- anticholinergics;
- sedatives;
- sleeping pills.
In case of overdose, symptoms such as:
- nausea;
- vomiting;
- overexcitement;
- convulsions;
- urinary retention;
- increased body temperature;
- increased sweating.
Side effects
- loose stool;
- dry mouth;
- allergic manifestations;
- burning sensation in the anus;
- constipation;
- dilated pupils;
- feeling of heartbeat ;
- paresis of accommodation;
- feeling dizzy ;
- headache;
- drowsiness;
- difficulty falling asleep and/or staying asleep.
Anuzol No. 10 suppositories
Trade name : Anuzol International nonproprietary name: No Dosage form: Rectal suppositories Composition: 1 suppository contains active substances: xeroform (bismuth tribromophenolate and bismuth oxide complex) 0.10 g, belladonna thick extract (belladonna leaf extract) 0.02 g, zinc sulfate heptahydrate 0.05 g, excipients: glycerol (distilled glycerin), purified water, distilled monoglycerides (MGD), solid fat (vitepsol (brands N 15, W 35), supposir (brands NA 15, NAS 50)). Description: Torpedo-shaped suppositories of greenish-yellow or greenish-yellow with a brownish tint or light brown color, with the smell of xeroform. A barely noticeable white coating may appear on the surface of the suppository. Pharmacotherapeutic group: Other drugs for the treatment of hemorrhoids and anal fissures for topical use. Other drugs and their combinations
Pharmacological properties: Pharmacokinetics Xeroform (bismuth tribromophenolate) is a poorly soluble compound in water, so the likelihood of its systemic exposure is extremely low. Belladonna alkaloids are absorbed in the gastrointestinal tract.
Pharmacodynamics Antihemorrhoidal combination drug. Anuzol has antispasmodic, anti-inflammatory, antiseptic, analgesic, local anti-inflammatory, astringent and drying effects. Xeroform (bismuth tribromophenolate) is an antiseptic, anti-inflammatory, astringent and drying agent. Belladonna extract – has an M-anticholinergic and antispasmodic effect, reduces muscle tone of the gastrointestinal tract (GIT). Zinc sulfate is an astringent and antiseptic. Glycerol is used to change the osmotic pressure in different tissues, reduce swelling, and increase osmoticity. Indications for use: - hemorrhoids - anal fissures. Directions for use and dosage : Rectally. 1 suppository 1-3 times a day after a cleansing enema or spontaneous bowel movement. The maximum daily dose of the drug is 7 suppositories. The duration of the course of treatment is 10-14 days. Side effects: - allergic reactions - burning in the anus - dry mouth - constipation, loose stools - palpitations - dilated pupils, transient visual disturbances (paresis of accommodation) - tinny pain, dizziness - sleep disturbance, drowsiness. In these cases, you should stop using the drug and consult a doctor. Contraindications: - hypersensitivity to the components of the drug - intestinal atony - heart failure in the stage of decompensation, tachyarrhythmia, myasthenia gravis - aperture-angle glaucoma - prostate adenoma - pregnancy and lactation. Drug interactions: Cases of interaction or incompatibility of the drug Anuzol, rectal suppositories, with other drugs have not been described. Special instructions: Children. Due to the fact that clinical studies of the drug Anuzol, rectal suppositories, have not been conducted in children, use in childhood (up to 18 years) is possible only after consultation with a doctor. Features of the effect of the drug on the ability to drive a vehicle or potentially dangerous mechanisms. During the treatment period, care must be taken when driving vehicles and engaging in other potentially dangerous activities that require increased concentration, speed of psychomotor reactions and good vision. Overdose: Cases of overdose of Anuzol have not been reported. Overdose is possible if the method of administration is not followed (the drug is administered rectally) and if the drug is used in a daily dose of more than 7 suppositories. Symptoms: nausea, vomiting, psychomotor agitation, convulsions, urinary retention, decreased sweating, hyperthermia. Treatment: symptomatic. Release form and packaging: 5 suppositories are placed in a contour cell packaging made of polyvinyl chloride film laminated with polyethylene. 2 contour packages together with instructions for medical use in the state and Russian languages are placed in a cardboard pack. Storage conditions: Store in a place protected from light at a temperature not exceeding 25 °C. Keep out of the reach of children! Shelf life: 3 years. Do not use the drug after the expiration date. Conditions for dispensing from pharmacies: Without a prescription
Anuzol suppositories, instructions for use
Following the instructions for Anuzol, before using suppositories, you should cleanse the intestines (naturally or with an enema), after which you need to remove the suppository from the package using scissors. The suppository is administered rectally ( into the rectum ). Depending on the severity of the painful condition, it is recommended to use from one to three suppositories per day. The maximum possible number of suppositories used in 24 hours is seven.
Analogs
Level 4 ATC code matches:
Betiol
Olestesin
Proctosedyl
Ultraproct
Relief
Posterisan Forte
Posterisan
Bezornil
Procto-Glyvenol
Glivenol
Proctosan
Hepazolon
- Betiol;
- Glivenol;
- Neo-Anuzol;
- Posterisan;
- Proctosan;
- Relief;
- Ultraproct , etc.
Reviews about Anuzole
Generally, reviews of Anuzol suppositories as a means of relieving hemorrhoids and anal fissures are positive. Patients note the rather rapid action of the drug and its high efficiency.
Among the negative assessments of this remedy, the most common are indications of an unpleasant odor, palpitations and some inhibition of reactions . Also, some patients report the return of symptoms of the disease after stopping the use of suppositories.
This suggests that if Anuzol can independently help eliminate anal fissures burning , damage to the anorectal area , irritation it cannot completely get rid of hemorrhoids This drug is used to alleviate or eliminate the symptoms of the disease and, unfortunately, cannot completely eliminate its cause.
In this regard, at the first signs of hemorrhoids, you should consult a competent specialist who will select complex therapy that is adequate for your condition or recommend other treatment methods.
Three steps away from trouble
Rectal suppositories Anuzol
The practically irreversible process of thinning of the venous walls of the anus is nothing more than one of the forms of development of varicose veins, which prevents the full outflow of venous blood from the rectum with the appearance of characteristic painful nodules and nodes in the anus.
Most often, the onset of the formation of hemorrhoids as a disease in women coincides with the period of bearing a child, when the entire load falls on the lower parts of the body.
Metamorphoses occurring in the female body contribute to its development, but it makes itself felt, in almost 90% of cases, only after the birth of a child. At the very beginning of the development of the disease, the symptoms are almost imperceptible. The disease shows practically no signs of itself, and, therefore, no one treats it.
The next step in the development of hemorrhoids is periodic pain in the anus, accompanied by burning and itching.
They are often accompanied by the release of small drops of scarlet blood. If you do not contact a proctologist at this moment, the disease will very quickly progress further, bringing suffering, severe pain and the risk of possible bleeding. All this can be avoided if you consult a doctor in time. Modern medicine has many means and manipulations to help the patient avoid the negative effects of such a very unpleasant disease as hemorrhoids.
Anuzol price, where to buy
If we compare the prices of suppositories for hemorrhoids in Russian pharmacies, then this medicine is the “golden mean” in terms of price-quality ratio.
Depending on the pharmacy chain, the price of Anuzol No. 10 suppositories varies between 55-70 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Neo-anuzole suppositories 10 pcs JSC Dalkhimfarm
80 rub. order - Anuzol Biosynthesis rectal suppositories 10 pcsBiosynthesis OJSC
67 RUR order
- Anuzol Nizhpharm rectal suppositories 10pcsAO "Nizhpharm"
98 RUR order
Pharmacy Dialogue
- Anuzol (soup rec. No. 10) Biosynthesis JSC
70 rub. order
- Neo-Anuzol (sup. No. 10) DHF OJSC
60 rub. order
- Anuzol (soup rec. No. 10) Nizhpharm JSC
83 RUR order
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Pharmacy24
- Anuzol N10 suppositories PAT Monpharm, Ukraine
21 UAH. order
PaniPharmacy
- Anusol suppository Supp. Anuzol No. 10 Ukraine, Monpharm JSC
22 UAH order
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special instructions
The possible penetration of belladonna alkaloids through the blood-brain barrier and possible interaction with drugs that affect the central nervous system should be taken into account. In therapeutic doses, belladonna alkaloids have a moderate stimulating effect on the central nervous system, in large doses - an stimulating effect, in toxic doses - agitation, hallucinations, followed by inhibition and coma. The simultaneous administration of the drug and other drugs with anticholinergic activity should be avoided, as the likelihood of side effects increases. Belladonna (belladonna) extract helps reduce the rate of absorption of concomitantly used drugs due to inhibition of the motor function of the gastrointestinal tract. Impact on the ability to drive vehicles and machinery
During the treatment period, you should refrain from driving vehicles and engaging in other potentially hazardous activities that require increased concentration, speed of psychomotor reactions and good vision.