Contraindications
Before taking Senade tablets, you should familiarize yourself with the contraindications for use. The drug should not be taken if:
- strangulated hernia;
- intestinal obstruction;
- spastic constipation ;
- abdominal pain of unknown origin;
- peritonitis;
- acute inflammatory diseases of the abdominal cavity;
- cystitis;
- disturbances of water-electrolyte metabolism;
- for uterine and gastrointestinal bleeding;
- if you have hypersensitivity to the components present in the tablets.
It is also correct to take tablets with caution in case of kidney and/or liver disease, after abdominal surgery, as well as during pregnancy or the lactation period.
Indications and prohibitions for admission
The summary advises taking Senade:
- during constipation associated with weak peristalsis and hypotension of the colon;
- for hemorrhoids;
- cracks in the anal area;
- proctitis.
The medicine is used when it is necessary to regulate stool or to facilitate the evacuation of stool.
Senade is contraindicated in patients:
- with strangulated hernia;
- spastic type constipation;
- painful sensations in the abdomen of unknown etiology;
- inflammatory pathologies of the peritoneal organs;
- bladder infections;
- deviations in electrolyte-water balance;
- bleeding in the gastrointestinal tract and uterus.
The medication is prohibited for patients with individual intolerance to the component composition. Senade is not prescribed to pregnant and lactating women, people with liver or kidney pathologies, or during the rehabilitation period after abdominal surgery.
Side effects
For the digestive system: flatulence and colicky abdominal pain are possible. In case of long-term use of the drug, nausea , diarrhea , vomiting , as well as melanin deposition in the intestinal mucosa are possible. This is especially true when the drug is used in high doses.
For the urinary system: urine discoloration, hematuria , and albuminuria .
For the cardiovascular system: there may be vascular collapse.
For metabolism: water-electrolyte metabolism may be impaired.
Dermatological reactions: Skin rash may develop.
Symptoms and treatment of overdose
Accidentally exceeding the recommended amount of Senade can provoke diarrhea, complicated by dehydration. First aid is to increase fluid intake to replenish losses of water and electrolytes. In difficult cases, the patient needs hospitalization and rehabilitation measures.
If signs of overdose appear (dyspeptic disorders, severe dryness of the oral mucosa, cephalgia), the patient should contact the local clinic. When visiting a therapist, he needs to describe in detail the problems that have arisen and receive a scheme for restoring water and electrolyte balance.
Instructions for Senada (Method and dosage)
The laxative is taken orally once a day before bedtime with a drink or water.
Instructions for use of Senade are divided into two categories:
- dosage for children over 12 years of age and adults – one tablet once a day. If there is no effect, then you can increase the dose of the medicine to 2-3 tablets at a time;
- dosage for children from 6 to 12 years old – take the drug once a day, half a tablet. If necessary, you can increase the dose to 1-2 tablets at a time.
While the dosage selection process is taking place, you need to take the same dose for several days, gradually increasing it by half a tablet. If the maximum dosage has been reached, but bowel movements do not occur within 3 days, you should consult a doctor.
Senade as a cure for constipation
Basically, a natural and non-addictive remedy, Senade is used for symptomatic, chronic and habitual constipation, which can be caused by intestinal hypotension or sluggish peristalsis. The drug also facilitates bowel movements and regulates stool in case of hemorrhoids, proctitis, anal fissures and in the postoperative period. For each of these diseases, the laxative Senade has the necessary effect:
- Sluggish intestinal motility occurs in people with a sedentary lifestyle, resulting in habitual constipation. The medicine for constipation Senade, due to its irritating properties, enhances the peristalsis of the large intestine and increases the contractile activity of smooth muscle elements.
- Constipation caused by hypotension is eliminated as a result of the fact that the intestines respond to the effects of the strong laxative Senade by increasing the strength, amplitude and duration of peristaltic movements. As a result, due to its active contractions, normal bowel movements occur.
- With hemorrhoids, bowel movements cause severe discomfort and pain, which can be reduced by the laxative Senade. The drug softens the intestinal contents and, as a result, it does not injure the hemorrhoids. The same thing happens with anal fissures.
- Proctitis is an inflammation of the rectal mucosa, in which defecation causes great difficulty. To soften hard stool, which additionally irritates the inflamed mucous membrane, and to regulate stool, use the herbal remedy for constipation Senade.
- Take Senade once a day, in the evening, with odorless and tasteless tablets with water. For adults, the dose of the drug is 1 tablet (if there is no therapeutic effect, it can be increased to 2-3 tablets). It is not recommended to use the laxative Senade for more than two weeks in a row.
Analogs
Level 4 ATX code matches:
Slabicap
Kafiol
Guttasil
Senadexin
Laxigal
Senna leaves
Herbion Laksana
Castor oil
Dulcolax
Bisacodyl
Regulax Picosulfate
Regulax
Weak
Mukofalk
Guttalax
The drug has the following analogues for the active substance:
- Glaxenna;
- Bekunis dragee;
- X Prep;
- Regulax;
- Herbion Laksana;
- Pursennyd;
- Senna;
- Tisasen;
- Senadexin;
- Ex Lax;
- Senalex.
Indications for use
Senade is a laxative that increases intestinal motility, so the indication for its use is atonic bowel movements in the following situations:
- Hypotonic (low tone) or atonic (lack of tone) constipation due to insufficient activity of the intestinal peristaltic muscles.
- Lack of urge to defecate, feeling of intestinal fullness;
- Absence of functional constipation caused by sedentary work, low physical activity, stress, climate change, poor nutrition.
- Regulation of stool for proctitis, hemorrhoids, paraprocytic inflammation, anal fissures.
- Excess weight to reduce its short course.
- How to prepare the intestines before ultrasound, x-ray and endoscopic examinations of the internal organs of the abdominal cavity.
Reviews on Senada
After analyzing multiple reviews of the pills on the Internet, we came to the conclusion that the drug acts quite mildly, but in case of an overdose, the stomach hurts very badly and the body quickly dehydrates, so you should approach the selection of your personal dose with caution. However, there is no clear indication for use; to find out how many tablets to take, you need to select the quantity individually.
Also, different people said differently about how long it takes for Senade to work. Most often it was said about 8-10 hours, but it also happened that the drug began to act after just a few hours. In any case, it is almost impossible to guess how many hours the drug takes to work, so it is recommended to refrain from urgent matters after taking it in order to avoid awkward situations.
Studying the reviews of doctors, we can come to the conclusion that another disadvantage of this laxative is addiction, which occurs quite quickly - within three months from the start of use. After this, the intestines refuse to work without this drug.
Some have tried using Senade tablets for weight loss . At the same time, they note how to take the drug for these purposes - half an hour before meals, before each meal. However, when taking Senade for weight loss, the reviews are not the most positive, which is associated with addiction to the drug, so it should be used for no more than two weeks.
Description
Flat, round tablets with beveled edges, brown to dark brown in color with inclusions. The word “CIPLA” is embossed on one side of the tablet and a break line on the other.
Pharmacotherapeutic group : laxative of plant origin. ATX code - [A06AB06].
Pharmacological properties Has a laxative effect that occurs after 8-10 hours. The laxative effect is due to the effect on the receptors of the large intestine, enhancing peristalsis.
Price at Senada
The price of constipation tablets depends on the number of laxative tablets in the package. The approximate price of 20 pieces is 20-25 rubles. And if you want to know how much a large package of 500 pieces costs, then you can buy it in different pharmacies from 531 to 663 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Senade tablets 13.5 mg 500 pcs Cipla
RUB 554 order
Pharmacy Dialogue
- Senade tablets 13.5 mg No. 500 Cipla Ltd.
RUR 544 order
- Senade tablets 13.5 mg No. 20Cipla Ltd.
25 rub. order
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Pharmacy24
- Senade 13.5 mg N500 tablets Cipla Ltd.,India/ at virobn.Mediteb Specialties Pvt.Ltd.,India
363 UAH.order - Senadex+ N12 tablets LLC Astrapharm, Ukraine
7 UAH order
- Senadex Plus No. 12 tablets LLC "Zdravofarm", Ukraine
8 UAH order
PaniPharmacy
- Senade tablets Senade tablets. 13.5 mg No. 500 India, Meditab Specialties
356 UAH. order
- Senadex-plus tab. No. 12
8 UAH order
show more
Dosage form, composition and packaging
The drug is available in tablet form.
Round brown tablets with ridges and beveled edges contain the active substances senosides A and B from Senna aquifolia leaf extract, 13.5 mg, and additional ingredients:
- starch - carbohydrate;
- lactose;
- cellulose;
- talc;
- magnesium stearate;
- sodium lauryl sulfate;
- cellulose gum;
- methyl parahydroxybenzoate.
Senade is contained in a cardboard box containing 20 tablets in one foil strip. One package may contain 40, 60 or 500 tablets.
Country of origin: India.
Pharmacological properties
The cleansing effect of Senade is due to its effect on the mechanoreceptors of the colon located in the mucus layer. As a result of their mechanical irritation, the impulse is transmitted to the smooth muscle elements of the colon wall, which leads to increased peristaltic activity.
The strength, amplitude and duration of bowel movements increase. The intestines are emptied as a result of muscle contractions. Senade does not affect the consistency of the stool, cleansing is unchanged, the stool is hard.
Keep in mind that senade does not have a diuretic effect, as many people think about using it for weight loss.
After taking Senade tablets, the effect occurs within 8 hours. It is at this time that senade is transported through the gastrointestinal tract, in the large intestine senade activates sensitive mechanoreceptors, which in turn causes stool to remain in the intestine, causing defecation.
Pharmacokinetics
Senade is practically not absorbed through the gastrointestinal mucosa; its bioavailability is 5%.
Having reached the lumen of the colon, Senade is hydrolyzed to free anthraquinones under the action of enzymes of beneficial intestinal microflora. The main part is excreted in feces and a small amount through the kidneys.
Interaction with other drugs and alcohol
When using Senade with antiarrhythmic drugs (verapamil, digoxin, strophanthin, Egilok, Concor, Betaloc ZOK, carvedilol, anaprilin), it is necessary to monitor electrocardiographic parameters due to the possibility of reducing the level of potassium in the blood and, as a result, increasing the effect of antiarrhythmic drugs.
People taking long-acting medications should be aware that this effect may be reduced when taken together with Senade.
During treatment with Senade, alcoholic beverages should be avoided due to increased dehydration during long-term treatment of constipation.
The absorption of tetracyclines in combination with Senade is delayed.
special instructions
Senade does not limit the ability to drive vehicles, therefore it is allowed for drivers and people whose activities require increased attention to operate devices while on the move. However, possible individual intolerance should be taken into account.
If you take Senade for more than fourteen days, you can expect side effects.
If, as a result of taking the maximum permissible daily dose of Senade, this applies to both adults and children, the laxative effect does not occur, stop taking Senade and discuss further tactics with your doctor, possibly due to other causes of constipation.
During treatment with Senade, your urine may turn yellow-brown.