Viagra 100 mg No. 1 table.

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Home Health from A to Z Useful information Viagra (Sildenafil)

Date of publication: 04/04/2016

until January 31

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How should you take sildenafil?

Follow your doctor's instructions. Usually a man takes one tablet an hour before possible sexual intercourse. You should not take more than 1 tablet per day. This medicine is available in tablets of 25, 50 and 100 mg. Most patients start with 50 mg.

Even if you take sildenafil, you still need physical and mental stimulation and desire to get an erection. If the first dose of Viagra does not help you, contact your doctor. Your doctor may change your dose.

Sildenafil causes a number of common side effects:

headache
blood flow to the skin of the face and upper torso and, as a result, redness and increased temperature of these parts of the body
stomach upset
runny nose
changes in vision (objects appear blue)

Headache

– the most common side effect. Changes in vision are the least common. Talk to your doctor if you experience any side effects that bother you.

Contraindications and side effects

The drug should not be taken by young people under 18 years of age, children and women.

Prohibited for use if:

The man was diagnosed with individual intolerance to the components.
There is a ban on sexual activity due to heart disease (for example, heart failure or angina).
Liver function is seriously impaired.
As a result of optic neuropathy, vision was lost in one eye.

Prescribe with caution when:

Various deformities of the male genital organ.
Pathologies with a risk of bleeding.
Having had a heart attack or stroke in the last 6 months.
Dangerous types of arrhythmia.
Extremely low (up to 90 per 50 mm Hg) or high (more than 170 per 100 mm Hg) blood pressure.
Aggravated ulcers of the stomach and duodenum.
Existing degenerative disease of the eye shell.

When using Viagra, you need to be prepared for unwanted effects. As a rule, they are mild, temporary, or may be completely absent. The risk of development increases with increasing dosage of the drug.

The tablets may cause:

Nausea and diarrhea.
Pain in the abdomen, joints or back.
Insomnia and increased muscle tone.
Skin rashes and conjunctivitis.
Infection of the respiratory tract or genitourinary system.
Prostate dysfunction.

To avoid negative manifestations, it is important to follow the recommendations for use and dosage regimen.

Can everyone take sildenafil?

No. You should not use this drug if you are taking any of the following nitro medications:

isosorbide mononitrate (Ismo, Monoket, Imdur)
isosorbide dinitrate (Isordil, Sorbitrate)
sublingual nitroglycerin tablets or sprays (Nitrostat, Nitrolingual spray)
transdermal nitroglycerin pastes (Minitran, Nitro-Dur, Transderm-Nitro)

If you take sildenafil and experience chest pain, be sure to tell your doctor that you are using it and when you last took it.

Information provided by the American Academy of Family Physicians

Make an appointment Do not self-medicate. Contact our specialists who will correctly diagnose and prescribe treatment.

Make an appointment

What happens if a healthy man takes Viagra?

Sildenafil-based drugs, including Viagra, are indicated for use by men who experience erectile dysfunction. If a person is absolutely healthy, there is no point in taking pills. Although the drug has undergone clinical trials, it is best not to take it unless necessary. If only because it has side effects. For example, it is not a fiction that you can go blind from Viagra, but it rarely happens. Manufacturers of tablets warn about this in contraindications. In particular, Viagra use can cause vision problems such as loss of clarity and increased sensitivity to light.

If a healthy person decides to try it, there is a reduction in the refractory period (breaks between two sexual acts) by about 10 minutes. This is confirmed by a study published in January 2000 in the journal Human Reproduction.

That is, men can try the pill if they are interested. But we must remember that if the recommended dose is exceeded, there is a risk of a heart attack or prolonged erection (about 4 hours). The latter threatens the development of gangrene of the genital organ, which can lead to its amputation.

What you need to know before taking Viagra

First of all, you should stop taking Viagra if you have an allergic reaction to it. It should also not be taken if you are taking medications to treat pulmonary hypertension (in particular, Adempas is an antihypertensive drug that stimulates the enzyme guanylate cyclase).

You should also not use Viagra if you are taking nitrate medications (eg, nitroglycerin, isosorbide dinitrate) to treat heart pain, since the mechanism of action of the latter is also associated with the release of NO factor. As a result of this combined interaction, vasodilation may increase and this will lead to a sharp drop in blood pressure with possible loss of consciousness.

Before using Viagra, you should see your doctor to take your medical history to make sure you don't have conditions such as:

problems with the cardiovascular system (arrhythmia, arterial hypo- or hypertension, coronary heart disease);
problems with blood circulation;
retinitis pigmentosa (hereditary eye disease);
visual impairment;
blood diseases (for example, anemia, leukemia);
pulmonary veno-occlusive disease (complications of pulmonary hypertension, which affects small pulmonary veins);
liver and/or kidney diseases;
physical deformation of the penis (for example, Peyronie's disease).

It is also especially important to consult your doctor before starting this medication if you are pregnant or planning to become pregnant, or if you are breastfeeding a baby.

Viagra is approved for use from 18 years of age.

What is Viagra?

Viagra is a drug that is used to treat erectile dysfunction (impotence) in men.
It relaxes the muscles in the walls of blood vessels and increases blood flow to the penis. Viagra is a powerful, selective (selective) inhibitor of cycloguanosine monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5).

The pharmacological effect of this therapeutic action works by releasing nitric oxide (NO) in the corpus cavernosum through sexual stimulation. As a result of this, blood flow to the penis increases and its smooth muscle fibers relax.

Consequences of Viagra overdose

In case of an overdose of Viagra, various symptoms may be observed that are characteristic of this drug and are associated with its mechanism of action. As a result of such an overdose, the following consequences may occur:

collapse (acute disruption of the blood supply to vital organs);
deafness;
retinal damage or blindness;
damage to the penis due to prolonged erection;
heart attack (myocardial infarction).

This is why it is very important to always consult a healthcare professional before taking Viagra. You must always follow all doctor's instructions and read the instructions for the drug.

Compound

can
contain sildenafil In addition to sildenafil, the drug contains: microcrystalline cellulose, calcium hydrophosphate, crosscarmellose sodium, magnesium stearate.

Opadry blue and transparent are used to make the film coating tablet.

The composition of Viagra does not differ depending on the concentration of the active substance.

Viagra analogs

Level 4 ATX code matches:
Tornetis

Olmax Strong

Taxier

Dynamico

Revatio

Caverject

Levitra

Cialis

Tentex Forte

Rileys

Sildenafil

Yohimbine hydrochloride

Zidena

Papazole

Drugs similar to Viagra in their mechanism of action

Analogs of Viagra tablets are Afalase , Cialis , Verona , Zidena , Rileys , Impaza , Yohimbine Spiegel , Caverject , Yohimbine hydrochloride , Levitra , Sirbida .

Generics of Viagra

Viasan LF , Viagra gel , Women's Viagra , Capsules for men "Favorite" (Chinese natural Viagra) , Vizarsin , Dynamico , Maxigra , Vigrande , Silafil , Sildenafil (Vertex, Sandoz) , Tornetis , Erexesil , Vizarsin Ku-tab , Olmax Strong .

As a substitute for Viagra for men, drugs that are produced from plants and various parts of animals (for example, tortoise shell, deer antlers, Tibetan yak testicles, etc.) can be used: Boss Royal Viagra , Vuka-Vuka , Impaza , Sealex , Yohimbe forte , Biagra , Yarsagumba and other drugs.

Since the market is represented by a fairly large number of drugs to improve erection in men, the questions quite naturally arise: “What is better - Cialis or Viagra?”, “What to replace the drug with?”, “What to choose - Viagra or Dynamico ?”.

no clear answer which is better - Viagra or Levitra , Viagra or Cialis , Viagra or Dynamico .

Dynamico is a synonym for the drug, that is, it is based on the same active ingredient as Viagra. The only differences between both products are the manufacturer and the price ( Dynamiko is somewhat cheaper than its structural counterpart).

Comparing Viagra with Levitra or Cialis is not entirely correct, since the drugs have different active ingredients and, therefore, different mechanisms of action. Cialis is taken approximately 10 minutes before sexual activity, Levitra - 20 minutes, Viagra - half an hour to an hour.

At the same time, the duration of action of the drugs is also different: for Viagra it is 4 hours, for Levitra - from 4 to 10 hours, for Cialis - up to 36 hours ( Cialis 40 mg is valid for up to 72 hours).

The effect of using Levitra and Cialis does not depend on food intake (or the amount eaten), in addition, Levitra is compatible with alcohol, and alcohol does not have a significant effect of Cialis As for Viagra, this drug is best taken on an empty stomach.

Often the price of analogues is lower than the price of the original drug. So, as a more affordable Russian analogue, you can buy Sildenafil .

What you need to know about Viagra

Before taking Viagra, you should see your doctor to take a complete history and evaluate your medical condition to make sure this drug is appropriate for your specific case.

Sources

Viagra / Drugs.com (English)

Viagra / State register of medicinal products (ukr.)

Medmarket Pharmacy24 provides comprehensive and reliable information on issues of medicine, health and well-being, however, diagnosis and choice of treatment methods can only be made by your attending physician! Self-medication may be unsafe for your health. Medmarket Apteka24 is not responsible for possible negative consequences resulting from the use by users of apteka24.ua of the information posted on the site.

Viagra price

How much does Viagra cost in Ukrainian pharmacies?

In Ukraine, the price of Viagra 50 mg tablets No. 1 is on average 375 UAH, the cost of 100 mg tablets No. 1 is about 350 UAH.

You can buy 50 mg tablets No. 4 at a pharmacy for 700-750 UAH, the price of 100 mg tablets No. 4 in pharmacies in large cities (for example, in Odessa or Kiev) is from 1050 UAH.

Viagra price for men in Russian pharmacies

Tablets for men 50 mg No. 1 in Russian pharmacies cost an average of 730 rubles, 100 mg No. 1 - from 870 rubles. Viagra tablets 50 mg No. 4 cost from 2.6 thousand rubles, 100 mg No. 4 - from 3.2 thousand rubles.

Where to buy Viagra online with delivery?

Numerous online pharmacies offer inexpensive and often home delivery of the drug, which ship goods to all major cities of Russia (including Omsk, Krasnodar, Murmansk, Volgograd, Novosibirsk, St. Petersburg, etc.) .

In online stores, the assortment is represented not only by the original drug, but also by its more affordable generics. Through them you can order and buy Generic Viagra, Viagra Soft, the Russian powerful drug Russian Super Viagra, as well as the medicine for women “Female Viagra” and many other products.

The cost of generics for men is usually approximately half the cost of the original (depending on the manufacturer); you can buy female Viagra in Moscow for a price starting from 800 rubles, in Kiev - from 120 UAH.

Viagra for free - what is it?

In many cities, advertisements began to appear (including electronic advertisements on forums) indicating “Viagra for free.” The question naturally arises - what is it?

So, most likely, the person who called the number specified in the ad will be asked to pick up the pills at the address given by the seller, place an order online, or order delivery of the goods by mail.

Under such conditions, it is impossible to be completely sure of your purchase and whether the drug will turn out to be a counterfeit, and the transaction will not be a common scam.

People who want to purchase a truly high-quality product at an affordable price and do not want to take risks can place an order at the online pharmacy https://zakaz-viagra.ru/.

Some buyers may suspect a fake, because the price of generics Viagra, Levitra and Cialis on the website is significantly lower than the price of original drugs. Thus, the price of Viagra in Russia is about 3200-4000 rubles for a pack of 4 tablets, in Ukraine - from 1 thousand UAH, in In Kazakhstan, tablets can be purchased for an average of 12,450 tenge. Generics cost at least half as much.

This is due to the fact that their manufacturers do not spend money on developing the product and conducting clinical trials of its use, but produce tablets according to an already existing recipe. At the same time, however, without having the right to sell them under a proprietary name.

When ordering through an online pharmacy, you can specify delivery conditions (delivery by mail, courier or pickup), as well as the possibility of purchasing a product in bulk.

Online pharmacies in RussiaRussia
Online pharmacies in UkraineUkraine
Online pharmacies in KazakhstanKazakhstan

ZdravCity

Viagra tablets p.p.o.
100 mg 2 pcs. Fareva Amboise/Pfizer Inc. RUB 1,736 order
Viagra tablets p.p.o. 50 mg 4 pcs. Pfizer PGM/Fareva Amboise
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Viagra tablets p.p.o. 25 mg 1 piece Fareva Amboise/Pfizer Inc.
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Viagra tablets p.p.o. 100 mg 1 piece Fareva Amboise/Pfizer Inc.
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Viagra tablets p.p.o. 50 mg 2 pcs. Fareva Amboise/Pfizer Inc.
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Pharmacy Dialogue

Viagra tablets 100 mg No. 2Pfizer
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Viagra tablets 50mg №1Pfizer
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Viagra tablet 25mg №1Pfizer
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Viagra tablets 50mg No. 4Pfizer
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Pharmacy24

Viagra 100mg N1 tablets Fareva Amboise, France
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Viagra 50 mg No. 4 tablets Pfizer P.J.E., France
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Viagra 50 mg No. 1 tablets Pfizer P.G.E., France
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PaniPharmacy

Viagra ODT tablet. p/o 50 mg No. 2
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Viagra tablets Viagra coated tablets 100 mg No. 1 France, Fareva Amboise
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Viagra tablets Viagra coated tablets 100 mg No. 4 France, Fareva Amboise
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Viagra tablets Viagra film-coated tablets 50 mg No. 4 France, Fareva Amboise
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Interaction

Sildenafil is metabolized in the liver , mainly under the influence of isoenzymes and partly under the influence of CYP2C9, therefore inhibitors of these isoenzymes reduce, and their inducers, accordingly, increase the clearance of sildenafil .

Thus, 0.8 grams of cimetidine , which is a nonspecific inhibitor of CYP3A4, in combination with 0.05 grams of sildenafil provokes an increase in the plasma concentration of the latter by 56%.

When taking 0.1 grams of sildenafil in combination with erythromycin , which is a specific inhibitor of CYP3A4 (in the case when erythromycin is taken twice a day, 0.5 grams for 5 days), after a constant concentration of erythromycin in the blood is achieved, The AUC of sildenafil increases by 182%.

Simultaneous single administration of 0.1 grams of sildenafil with 1.2 grams of sanquinavir , which is an inhibitor of CYP3A4 and HIV protease , with a frequency of use of the latter three times a day: against the background of achieving a constant plasma concentration of sanquinavir the AUC of sildenafil increases by 210%, and Cmax - by 140%. However, sildenafil does not change the pharmacokinetics of sanquinavir .

Ketoconazole and itraconazole , which are more potent inhibitors of the CYP3A4 isoenzyme, may have a stronger effect on the pharmacokinetic parameters of sildenafil .

With the simultaneous use of 0.1 gram of sildenafil (once) and ritonavir (0.5 gram twice a day), which is a potent inhibitor of cytochrome P450 isoenzymes and an HIV protease inhibitor, after achieving a constant plasma concentration of ritonavir the AUC of sildenafil increases 11 times (by 1000%), and Cmax - 4 times (by 300%).

After 24 hours, the plasma concentration of sildenafil is 200 ng/ml, while after a single use of sildenafil this figure is 5 ng/ml.

Patients who take sildenafil in the recommended dosages and additionally receive potent CYP3A4 inhibitors

Sildenafil metabolism pathway and potentiates the hypotensive effect of nitrates (both when used for acute indications and during long-term treatment with these drugs). In this regard, taking sildenafil with nitric oxide donors or nitrates .

A single dose of antacid drugs ( aluminum hydroxide or magnesium hydroxide ) does not affect the bioavailability of the drug.

symptomatic hypotension may develop during the simultaneous use of sildenafil and α-blockers .

No significant interaction of the drug with warfarin (0.04 grams) and tolbutamide (0.25 grams) has been established. Also, the interaction of sildenafil at a dose of 0.1 gram with amlodipine when using these drugs in patients with arterial hypertension .

In addition, sildenafil :

at a dose of 0.1 grams does not change the pharmacokinetics of HIV protease inhibitors at their constant concentration in the blood;
at a dose of 0.05 grams when taken simultaneously with 0.15 grams of acetylsalicylic acid does not provoke an additional increase in the duration of bleeding ;
at a dose of 0.05 grams in healthy volunteers does not increase the hypotensive effect of ethanol with a maximum level of the latter in the blood of about 80 mg/dl;
does not provoke the occurrence of additional side effects when used simultaneously with antihypertensive drugs .

Viagra and alcohol

Viagra and alcohol - compatible or not? There is no categorical prohibition on taking these products in combination; from a chemical point of view, they do not interact with each other.

However, if sildenafil enters the stomach with alcohol, its absorption and therefore its rate of action are slowed down. In addition, when the drug is used simultaneously with alcoholic beverages, the load on the body as a whole and in particular on the heart muscle (which should be taken into account by people suffering from hypertension or heart disease ).

Thus, despite the fact that Viagra and alcohol are not mutually exclusive drugs, they should be combined as rarely as possible and in a minimal dose.

Scientists have concluded (and reviews of men who have taken Viagra confirm this) that in order to feel normal when using the drug in combination with alcohol, you should drink no more than 100 grams of vodka, 700 grams of beer or 450 grams of wine.

Symptoms of Viagra overdose

When taking Viagra in the above prescribed dosages prescribed by a doctor or in a dose exceeding the daily dose, symptoms of an overdose of this medicine may be observed:

chest pain, which can radiate (give) to other parts of the body;
dyspnea;
painful erection that does not go away for more than 4 hours;
tinnitus;
interruptions in heart rhythm;
orthostatic hypotension (a sharp drop in blood pressure);
visual impairment.

If you observe such symptoms, you must stop subsequent use of Viagra and seek help from a medical specialist.