Cynarix - instructions for use, reviews

Cinarix for liver diseases

Cynarix is ​​a classic hepatoprotector.
Its use in cases of liver dysfunction can improve its functioning, cleanse and protect against toxic effects, and stimulate the restoration of liver tissue. It is recommended to use this remedy for indigestion, alcohol intoxication, and consumption of fried and spicy foods. For liver diseases, including viral hepatitis, cirrhosis, a treatment course using Cynarix tablets may take 4 to 6 months. It all depends on the diagnosis and stage of the disease. The drug can also be used as a prophylactic agent.

Detailed instructions for admission

The article presents detailed instructions for use, which spell out important points regarding storage conditions, indications, possible analogues, composition, pharmacology, price range, conditions of use during pregnancy/breastfeeding, contraindications, overdose, combination with other drugs, release form. All this data should be carefully studied so that no negative consequences arise in the future.

What is the pharmacology of the drug?

According to the instructions for use, Cynarix is ​​a dietary supplement that helps maintain the functional state of the liver, as well as the entire gastrointestinal tract.
The instructions say that the drug promotes the production of bile, thereby preventing its stagnation. It follows that this remedy has a complex effect on the body and helps increase the secretion of enzymes. The substances contained in the composition minimize lipid levels, which further leads to a decrease in cholesterol in the blood. The substances have a hepatoprotective effect on liver cells, thereby intensifying the neutralizing activity of the organ.

The half-life is approximately 11 minutes. Based on many reviews, one hour after taking the drug, the production of bile acid is noted, the duration of which is no more than three hours.

In what cases is admission permitted?

In what cases is it permissible to take Cynarix? This remedy must be taken if you have diseases such as:

• Chronic form of hepatitis;
• Intoxication of the body, which occurs in a chronic form;
• Cholecystitis (chronic);
• Cholestasis.

In addition, the drug can be prescribed after cholecystectomy. Sometimes the remedy can be prescribed for any digestive disorders, especially if a person eats a lot of fatty and heavy foods.

How to take the product correctly?

Adults, as well as children over 12 years of age, are prescribed Cynarix tablets in a dosage of one or two tablets twice a day; for children from six to twelve years of age, the dosage of the drug is one tablet, which must be taken twice a day.
The dosage of the solution to be taken during meals is no more than two teaspoons.

The total duration of treatment is several weeks, however, it can be adjusted by the doctor based on the severity of the disease.

Compound

This product is available in the form of a solution and tablets intended for oral administration.

Based on the instructions, the tablets contain the active substance - artichoke extract, as well as auxiliary components - cellactose, calcium citrate, calcium carbonate, magnesium stearate, silicon dioxide, sucrose, talc, collidon, green sikovit, methylcellulose, calcium carbonate, glycerin, wax, sikovit yellow.

The solution contains an active substance - artichoke extract. The product is available in bottles with a volume of 50, 100, 250 ml.

Did you know that the most common disease of the 21st century is liver disease? Find out more about liver disease:

Combination with other means

No drug combination with other drugs was noted.

Doctors advise consulting with a doctor before starting treatment. This must be done in order to eliminate the possibility of negative reactions.

Price for the drug

The price of this drug can vary significantly. In addition to this factor, factors such as:

• Individual pharmacy markup;
• The costs incurred by the company when transporting goods.

In addition, it is worth understanding that the article indicates the approximate price range in which the medicine is located. If you need to find out the exact cost, then you should contact your nearest pharmacy.

Russia

In Russia, the price of medicine ranges from 310 to 450 rubles.

Ukraine

In this country, this drug can be found at a price of 115 hryvnia.

Video: Artichoke. Useful properties and contraindications.

Indications for use of Cynarix

A dietary supplement in the form of tablets is recommended for patients with various disorders of the functioning of the biliary tract, in particular with functional dyskinesia, chronic cholecystitis, hepatitis and chronic intoxication with hepatotoxic substances.

According to reviews, Cynarix in the form of an oral solution is effective for cholestasis (insufficient bile secretion), postcholecystectomy syndrome (painful manifestations after removal of the gallbladder), and digestive disorders in people who regularly eat fatty and hard-to-digest foods. Similar to the tablet form, the solution is prescribed for biliary dyskinesia and dyspepsia.

With regular use of the drug, abdominal pain is reduced, constipation, nausea, bloating and flatulence stop.

special instructions

Cynarix is ​​not recommended for patients with diabetes mellitus due to the sucrose content in the supplement.

The oral solution is not prescribed to patients with epilepsy, alcoholics and children under 12 years of age, since the product contains alcohol.

Dietary supplements in the form of tablets can be prescribed during pregnancy and breastfeeding, since the drug does not have a negative, including teratogenic, effect on the child’s body.

Cynarix does not affect a person's ability to drive vehicles or operate dangerous machinery, but it should be borne in mind that the oral solution contains alcohol (1.35 g of alcohol per teaspoon).

The dietary supplement does not cause drowsiness.

Special instructions for the use of Cynarix

Oral solution: given the alcohol content in the drug, it should not be prescribed to children under 12 years of age, alcoholics and patients with epilepsy. Use with caution in patients with diabetes (contains sucrose). Pregnancy and lactation: Tablets : the use of tablets does not have a teratogenic or other negative effect during pregnancy and lactation. Oral solution : the drug in the form of an extract contains alcohol (34%). One teaspoon contains 1.35 g of alcohol, so it is not recommended to prescribe the drug in extract form during these periods. Impact on the ability to drive vehicles and work with potentially dangerous mechanisms. Does not affect. The use of the drug does not cause drowsiness. When using an oral solution , it should be taken into account that the drug contains alcohol.

Instructions for use

Each package of Cinarix contains 2 or 5 blisters of 12 tablets each. The cardboard package contains detailed instructions for using Cynarix, which are useful to read before starting treatment.

Composition of tablets

The active ingredient of the drug Cynarix is ​​artichoke leaf extract. It is supplemented with auxiliary components, and a separate set of substances is present in the shell (coating), which are responsible for the sweetish taste and greenish color of the tablet.

Artichoke leaf extract is quite effective because it contains the following components:

• chlorogenic acid, which increases bile secretion;
• luteonin (bioflavonoid), which inhibits cholesterol biosynthesis;
• cinaropicrin (sesquiterpene lactones), which activate the production of gastric juice.

After using Cynarix tablets, the choleretic effect occurs after half an hour.

Classification of choleretic drugs

Indications

Cynarix is ​​used in the following cases:

1. Treatment of pain and bloating in the epigastric region, especially with functional disorders of the biliary tract.
2. Auxiliary therapy for disorders of digestion and absorption of fats.
3. Along with other drugs in the general course of treatment of a complex of symptoms characterized by a violation of one or more liver functions.

The use of this dietary supplement is avoided in case of obstruction of the ducts that excrete bile or urine, in case of accumulation of a large amount of purulent contents in the cavity of the gallbladder, or in case of cholelithiasis.

Cynarix is ​​contraindicated in case of intolerance to the main or auxiliary components, as well as allergies to other plants of the Asteraceae family.

How to use?

A hepatologist or gastroenterologist will explain how to take Cynarix in a specific clinical case. The specialist also determines the duration of treatment.

In all cases, the tablet is taken orally immediately before meals or with food. Take Cynarix with a glass of clean water.

Doses

According to the instructions for use, Cinarix tablets are used by adults and children over 12 years of age, 1-2 tablets (400-800 mg of extract) 3 times a day. The duration of the therapeutic course is on average 2-3 weeks.

Special instructions for treatment

During treatment with Cynarix supplement, consider the following:

The dietary supplement contains lactose. Patients with lactose intolerance and lactase deficiency should pay attention to this. The product contains sucrose, so diabetics should take this into account if they are prescribed this supplement. Take with caution in the presence of concomitant diseases leading to biliary artesia or in case of serious liver pathologies. If positive dynamics are not observed or during therapy the patient experiences diarrhea and abdominal pain, then stop treatment and be sure to consult a doctor about this. If no positive dynamics are observed or the patient experiences diarrhea and abdominal pain during therapy, then stop treatment and be sure to consult a doctor about this.

If positive dynamics are not observed or during therapy the patient experiences diarrhea and abdominal pain, then stop treatment and be sure to consult a doctor about this.

If you experience abdominal pain, consult a doctor

While using Cynarix, it is recommended to refrain from drinking alcohol.

Use of the drug Cinarix

Tablets: orally for adults and children over 12 years of age, 1–2 tablets 3 times a day during or after meals; children aged 6 to 11 years (who can swallow tablets) - 1 tablet 2 times a day. The course of treatment depends on the nature and severity of the disease and is determined by the doctor individually. Oral solution: adults and children over 12 years old, 1–2 teaspoons per day before meals. The duration of the course depends on the course and severity of the disease and is determined by the doctor individually, on average - 2 weeks.

Description and instructions for the drug Cynarix

Cynarix is ​​not a drug, but a biologically active food supplement that has choleretic properties. This product contains artichoke extract. This natural raw material contains various substances that stimulate the production of bile, gastric juice, and a decrease in the concentration of fats in human blood. Approximately half an hour after using Cynarix, bile production increases and remains at this level for another three hours. However, you need to understand that the treatment of pathologies of the bile formation and bile excretion system, as well as the digestive system in general, cannot be carried out with the help of supplements. Also, if you decide to use Cynarix, you need to consult your doctor.

Cynarix is ​​used for:

• Cholecystitis, hepatitis (in chronic form);
• Dyskinesia (impaired motor function) of the biliary tract;
• Poisoning with substances toxic to liver tissue;
• Dyspepsia (functional);
• Stagnation of bile;
• Abuse of fatty foods;

This supplement has two forms of release - tablets and oral solution. The tablets are taken during or after meals, and the solution is taken immediately before meals. The instructions for the drug Cinarix indicate that the duration of its course should be determined by the doctor depending on the patient’s condition. Average standard single dosages are one to two spoons of solution or one to three tablets.

Cynarix is ​​contraindicated for:

• Obstruction of the biliary tract, including empyema (accumulation of pus) of the gallbladder;
• Intolerance to this supplement;
• Acute liver failure, acute hepatitis;

- the solution is contraindicated in -

Pregnancy, lactation and children under twelve years of age (due to alcohol content).

Side effects of Cynarix

Long-term use of this supplement may cause diarrhea (functional, associated with increased bile production). If the patient's health is affected by an allergic reaction, you should stop taking Cynarix.

Reviews about this drug

There are few reviews about this product on the Internet. Among the obvious advantages are the absence of side effects, as well as the high effectiveness of the product. In addition, this drug has a large number of analogues, which makes it easy to choose another drug if this is not suitable.

All patients consider the disadvantages of this drug to be that this drug is still a dietary supplement, and therefore its effectiveness has not been scientifically proven. In addition, some people do not like the high cost of the drug, because... they think it's too high.

Your opinion is important to us, so please leave your review about this drug.

Pharmacological properties of Cynarix

Artichoke extract has a complex effect on the human body. Cynarix is ​​indicated for use as a means of supporting the functional state of the liver, biliary tract and gastrointestinal tract.

The medication, preventing stagnation of bile in the biliary tract, gently stimulates its production and increases the secretion of pancreatic enzymes. Cynarix also enhances intestinal motor function.

Artichoke extract contains flavonoids, caffeylquinic acids and sesquiterpene lactones. These components reduce lipid content, reducing cholesterol levels in the blood. Sesquiterpene lactones increase bile secretion. Caffeylquinic acids have a hepatoprotective effect on liver cells.

A relevant increase in bile acid production occurs 1 hour after administration of Cynarix and persists for 3 hours. The serum half-life of artichoke is approximately 11 minutes.

Pharmacological properties of the drug Cynarix

Standardized artichoke extract gently stimulates bile production over a long period, preventing stagnation of bile in the biliary tract, and enhances the secretion of pancreatic enzymes. The main ingredients of artichoke extract are caffeylquinic acids, flavonoids and sesquiterpene lactones. Caffeylquinic acids increase bile secretion. The antihyperlipidemic effect is associated with methionine, which affects cholesterol biosynthesis. Sesquiterpene lactones stimulate gastric secretion. Caffeylquinic acids have a hepatoprotective effect. The half-life of artichoke components from blood serum is 11 minutes. 1 hour after administration of artichoke extract, a relevant increase in bile acid production is noted, which persists for up to 3 hours.

Side effects

This drug is well tolerated, because... practically does not cause side effects. However, in some reviews, people note that this dietary supplement can cause a negative reaction, which is usually associated with the appearance of an allergic reaction, such as diarrhea.

The drug in the form of tablets when taken orally does not cause a negative reaction in pregnant women and newborns. In addition, you also need to take into account that the solution consists of 34-35% alcohol.

Overdose

There have been no reports of overdoses to date.

However, doctors still do not exclude the possibility of these conditions occurring. That is why, if you suddenly begin to notice any symptoms when taking the drug in large quantities that were not there before, you should immediately stop taking it and seek medical advice. help.

Contraindications

The drug is contraindicated for use in conditions such as:

• Disturbances in the functioning of the liver, which occur in severe form;
• Empyema of the gallbladder;
• Acute form of hepatitis;
• High sensitivity to individual components of the product.

Considering that the product contains a large amount of alcohol, it should not be taken by children under 12 years of age, as well as by people suffering from epilepsy. Considering that the product contains sucrose, this drug is not recommended for use by people who have been diagnosed with diabetes.

Taking the drug during pregnancy

This product is safe and therefore can be taken during pregnancy

However, doctors still advise caution when taking it.

You should also be careful when breastfeeding. If your baby becomes capricious during use, you should stop taking the medication.

If during the rest the child’s condition has stabilized, this means that taking the drug should be postponed or breastfeeding should be stopped.

What analogues exist for this product?

This product has a huge number of analogues. Among such means are Glutargin, Bioherba, Gepazin, Ursoliv, Artibel, Tishok, Holegon, Odeston, Parazol, Hepel N, Choludexan, Kamnelom, Flamin, Flavia, Ursosan, Ursodez, Opistorcid, Artizhel and others.

It is worth considering that only a qualified doctor, but not the patient himself, can select a similar remedy. This is due to the fact that self-treatment can significantly worsen the patient’s situation.

Compound

1 film-coated tablet contains:

active ingredient: dry aqueous artichoke leaf extract (Exatractum Cynarae e folium aquosum siccum) (80%), standardized for caffeoylquinic acid content to at least 3%, listed for chlorogenic acid content - 68.75 mg (dry artichoke leaf extract (Cynara scolymus L ) (4-6: 1) (extractant: water) - 55 mg

in artichoke extract: maltodextrin, colloidal silicon dioxide

general: colloidal silicon dioxide, celactose 80, copolyvidone, crospovidone, talc, magnesium stearate

shell: sucrose, talc, titanium dioxide (E 171), acacia (gum arabic), methylcellulose, calcium carbonate, glycerin 85%, indigo (E 132), quinoline yellow (E 104), methacrylate copolymer (type B), montaglycol wax.

Analogs

Galstena

Galstena is a relatively cheap substitute for Cynarix. The homeopathic remedy is available in the form of oral drops and tablets. The average cost of packaging is 450-500 rubles. The manufacturer of the hepatoprotector is the Austrian company Richard Bittner AG.

The drops and tablets contain naturopathic components that have hepatoprotective, immunomodulatory, choleretic and anti-inflammatory effects. The active ingredients of Galstena are milk thistle, celandine, medicinal dandelion, phosphorus, sodium sulfate.

1. Helps fight inflammatory processes in the liver and gall bladder.
2. Helps reduce the lithogenicity of bile, as a result of which, with regular use of the hepatoprotector, gallstone disease can be avoided.
3. Normalizes lipid metabolism. Active components reduce the level of bad cholesterol in the blood, preventing the formation of cholesterol plaques in blood vessels.
4. Relieves spasms in the gallbladder and bile ducts. Also, the active ingredients normalize the passage and synthesis of bile, and also reduce its saturation with lipids.
5. Successfully fights fibrosis and cirrhosis of the liver.
6. Reduces the severity of intrahepatic cholestasis and cytolysis syndrome.
7. Eliminates symptoms of dyspepsia.

Indications for the use of a homeopathic remedy are hepatosis, hepatitis, cirrhosis, fatty liver, atherosclerosis, non-calculous cholecystitis, biliary dyskinesia, liver failure, chronic pancreatitis. You can take Galstena for preventive purposes.

It is advisable to take the tablets before meals. They need to be dissolved. It is enough to consume 1-2 tablets per day. Drops should also be consumed before meals. It is optimal to drink 5-10 drops 2 times a day. The duration of use of Galstena is determined by the attending physician on an individual basis.

Contraindications for use are alcohol dependence, hypersensitivity to the components of the drug, childhood

The hepatoprotector is prescribed with caution to pregnant and lactating women

Karsil Forte

Karsil Forte is also an excellent analogue of Cynarix. This medication is available exclusively in the form of capsules for oral administration. The hepatoprotector is produced by the Bulgarian company Sopharma. The price of one package starts from 370 rubles.

The active ingredient is milk thistle fruit extract. The plant contains a mixture of flavonolignan isomers. Karsil Forte has a choleretic and hepatoprotective effect, and also has a positive effect on lipid metabolism

• Normalization of liver functionality. Karsil Forte successfully fights fibrosis and any degenerative changes in the liver.
• Stabilization of bile synthesis and passage. Also, after taking Karsil Forte, the lithogenicity of bile decreases, which helps prevent the formation of cholesterol stones in the gall bladder.
• Antispasmodic. The active component of the medicine relieves spasms in the intestines, gall bladder and bile ducts.
• Boosting immunity.
• Antioxidant action. Karsil Forte binds free radicals, thereby neutralizing their negative effects on hepatocytes.
• Improving microcirculation processes.
• Stimulation of the synthesis of structural proteins and phospholipids in hepatocytes.

Indications for the use of the drug are toxic liver damage, hepatitis, cirrhosis, liver steatosis, bile stagnation, bile duct dyskinesia, non-calculous cholecystitis, liver intoxication. It can be taken for preventive purposes.

It is recommended to take 1 capsule 3 times a day. Take the medicine with water. The average duration of treatment is 3 months, sometimes longer. For prevention purposes, it is enough to drink 1 capsule 2 times a day for 1-2 months.

1. Children's age (up to 12 years).
2. Hypersensitivity to the components of the drug.
3. Pregnancy.
4. Lactation.
5. Lactase deficiency, galactosemia.
6. Ovarian/prostate/breast cancer, uterine fibroids, benign prostatic hyperplasia.

When using Carsil Forte capsules, diarrhea, nausea, vestibular disorders, and allergic reactions are possible. Side effects are eliminated on their own immediately after stopping the medication.

Pharmacological properties

The main components that determine the effectiveness of artichoke sativum leaf extract are biologically active substances such as caffeylquinnic acids, flavonoids (for example, luteolin) and sequiterpene lactones. Caffeylquinni acids increase the level of bile secretion and determine the main mechanism of therapeutic action for dyspeptic disorders. The antihyperlipidemic effect is due to the presence of luteolin, which causes a significant inhibition of cholesterol biosynthesis. Bitter sesquiterpene lactones (eg, cinaropicrin) stimulate gastric acid secretion.

The choleretic effect develops in less than 30 minutes after using artichoke leaf extract. The absorption mechanisms for pharmacologically active caffeylquinic acids, such as chlorogenic acid, caffeic acid (its metabolite) and luteolin (a flavonoid), are unknown. The site of absorption is considered to be the upper parts of the digestive tract and colon, which can be concluded based on the increase in the concentration of caffeic acid in the blood plasma and T max values ​​of 6-7 hours. 33% and 100%, respectively, of oral administration of chlorogenic and caffeic acid are absorbed in the small intestine.

Metabolism and excretion

Chlorogenic acid is hydrolyzed in the stomach by breaking down into caffeic and quinic acids. Caffeic acid is primarily eliminated by glomerular filtration.

Cynarix for gallbladder diseases

According to medical observations, about 15% of the adult population suffers from diseases of the gallbladder and bile ducts. The most common pathology is gallstone disease, in which stones of different sizes form in the gallbladder or ducts. If the formations are small in size, the doctor prescribes conservative treatment, which includes taking medications that destroy stones.

The use of the drug Cynarix does not destroy stones, but eliminates stagnation of bile, reduces the level of cholesterol and lipoproteins, and stimulates the secretion of bile. Thanks to these properties of the drug, the functioning of the gallbladder improves and the risk of developing stones in this organ or its ducts is reduced.