Strepsils intensive 24 pcs. honey-lemon lozenges
pharmachologic effect
Non-steroidal anti-inflammatory drug.
Composition and release form Strepsils intensive 24 pcs. honey-lemon lozenges
Active ingredient - flurbiprofen 8.75 mg; auxiliary components: macrogol 300 5.47 mg, potassium hydroxide 2.19 mg, lemon flavor (502904 A) 3.6 mg, levomenthol 2 mg, honey 50.4 mg, liquid sucrose 1407 mg, dextrose 1069 mg.
Description of the dosage form
Round tablets of translucent caramel mass from light yellow to light brown, with the image of the letter S on both sides of the tablet. The presence of air bubbles in the caramel mass and slight unevenness of the edges are allowed. A white coating may appear.
Directions for use and doses
The tablets must be dissolved in the mouth until completely dissolved. When resorption, the tablet should be moved throughout the oral cavity to avoid damage to the mucous membrane at the site of resorption. It is recommended that adults and children over 12 years of age take one tablet as needed. Do not take more than five tablets in 24 hours. You should not take the tablets for more than 3 days.
Pharmacodynamics
The mechanism of action of flurbiprofen is associated with inhibition of the enzymes cyclooxygenase 1 and cyclooxygenase 2 with subsequent inhibition of the synthesis of prostaglandins - pain mediators. Has anti-inflammatory and analgesic effects. The drug does not have an antimicrobial effect. The effect of the drug begins 30 minutes after the tablet begins to dissolve in the oral cavity and lasts for 2-3 hours.
Pharmacokinetics
Absorption is high. Communication with blood plasma proteins is more than 99%. The maximum concentration in plasma (Cmax) is achieved after 30-40 minutes. It is mainly metabolized through hydroxylation and excreted by the kidneys. The half-life (T1/2) is 3-6 hours.
Indications for use Strepsils intensive 24 pcs. honey-lemon lozenges
As a symptomatic remedy to relieve sore throat in infectious and inflammatory diseases of the oral cavity and pharynx.
Contraindications
Hypersensitivity to any of the components of the drug; gastric ulcer (exacerbation); bronchial asthma and rhinitis while taking acetylsalicylic acid or other non-steroidal anti-inflammatory drugs; children's age (up to 12 years); deficiency of glucose-6-phosphate dehydrogenase, pregnancy, lactation.
Use with caution in: hyperbilirubinemia (including Gilbert, Dubin-Joison and Rotor syndrome), chronic circulatory failure, edema, arterial hypertension, hemophilia, hypocoagulation, gastric or duodenal ulcer (in remission, in history), liver and/or kidney failure, decreased blood clotting, inhibition of bone marrow hematopoiesis, hearing loss, pathology of the vestibular apparatus. When prescribed to elderly people, use of the drug is possible only after consultation with the attending physician.
Application of Strepsils intensive 24 pcs. lozenges honey-lemon during pregnancy and breastfeeding
Hypersensitivity, children's age (up to 6 years).
special instructions
Patients with diabetes should note that the tablet contains about 2.5 g of sugar.
If a sore throat is combined with a significant increase in body temperature, taking the drug can only be recommended by a doctor.
If it is necessary to determine 17-ketosteroids, the drug should be discontinued 48 hours before the study. If a high temperature persists, a headache, or other undesirable effects occur, you should consult a doctor.
Do not exceed the dose indicated in the instructions.
Overdose
Symptoms of an overdose of flurbiprofen can manifest themselves as: when taking 1 g - drowsiness, more than 1.5 g - agitation, 2.5-4 g - nausea, headache, dizziness, epigastric pain, diplopia, miosis, hypotonicity, more than 4 g - depression of consciousness up to to coma. In case of overdose, the drug should be stopped, treatment: symptomatic.
Side effects Strepsils intensive 24 pcs. honey-lemon lozenges
Adverse reactions related to the use of Strepfen are mainly associated with distortion of taste perception and elements of paresthesia (burning, tingling or tingling). Ulceration of the oral mucosa is possible. Undesirable side effects characteristic of drugs from the NSAID group can be observed when taking the drug orally at a dose of 50-100 mg 2-3 times a day (12-30 Strepfen tablets per day).
From the gastrointestinal tract: dyspepsia (nausea, vomiting, heartburn, diarrhea), NSAIDs - gastropathies, abdominal pain; liver dysfunction; with long-term use in large doses - ulceration of the mucous membrane of the gastrointestinal tract, bleeding (gastrointestinal, gingival, hemorrhoidal).
From the cardiovascular system: increased blood pressure, tachycardia, heart failure.
From the hematopoietic organs: rarely - anemia (iron deficiency, hemolytic, aplastic), agranulocytosis, leukopenia, thrombocytopenia.
From the nervous system: headache, dizziness, drowsiness or insomnia, asthenia, depression, amnesia, tremor, agitation, rarely - ataxia, paresthesia, impaired consciousness.
From the urinary system: tubulointerstitial nephritis, edema syndrome, impaired renal function.
Allergic reactions: skin rash, itching, urticaria, bronchospasm, photosensitivity, Quincke's edema, anaphylactic shock.
Other: hearing loss, tinnitus, increased sweating.
Drug interactions
Inducers of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites. Reduces the effectiveness of uricosuric drugs, enhances the effect of anticoagulants (increases the risk of bleeding), antiplatelet agents, fibrinolytics, side effects of mineral and glucocorticosteroids, estrogens; reduces the effectiveness of antihypertensive and diuretics; enhances the hypoglycemic effect of sulfonylurea derivatives. Increases the concentration of lithium and methotrexate in the blood.
Strepsils
Strepsils is an antiseptic combination drug for topical use in otolaryngological and dental practice for the treatment of infectious and inflammatory diseases of the mucous membrane of the oral cavity and pharynx. Has an antibacterial effect. Shows activity against a wide range of microorganisms, including gram-positive and gram-negative. It also has an antifungal (fungicidal) effect. Strepsils is developed on the basis of two pharmacologically active substances: amylmetacresol and dichlorobenzyl alcohol. Amylmetacresol “leaks” into the protein structure of bacteria, having a destructive effect on them. Dichlorobenzyl alcohol, in turn, eliminates microorganisms by dehydrating their shells. In addition, Strepsils contains natural additives as excipients (anise, eucalyptus and lemon oil, honey, peppermint oil, menthol), which complement and enhance the therapeutic effect of the active ingredients. The above features of the drug allow it to be used with high efficiency in patients intolerant to antibiotics.
As is known, the cold factor forces our body to “turn on” protective mechanisms: vasodilation, increased permeability of vascular walls, release of histamine into the bloodstream, irritation of respiratory tract receptors. As a result, characteristic symptoms begin to appear: difficulty breathing through the nose, excessive secretion of mucus from the nasal cavity, coughing, sneezing, fever, headache. However, the most important symptom of a cold is a sore throat. It is this that most often forces people to seek medical help, since it causes obvious discomfort, incapacitates work, and complicates communication.
When an acute respiratory disease occurs, there is almost always a lack of time to accurately identify its causative agent. In this regard, as a rule, the patient will be prescribed antibiotics. However, as mentioned above, antibiotic therapy is by no means always justified, especially if it is used as part of self-medication. Systemic side effects and antibiotic resistance are not the entire list of negative factors associated with the uncontrolled use of antibiotics. The optimal choice in such cases may be strepsils. Its regular “clients” are traditional pathogens of acute respiratory infections: Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pyogenes. As laboratory studies have shown, the pharmacological effect of strepsils developed faster compared to other similar over-the-counter drugs. Strepsils can be used independently without medical prescription, not only for adults, but also for children over the age of 5 years. According to general recommendations, the drug should be taken one tablet every 2-3 hours. The maximum number of tablets taken per day should not exceed 8. If the symptoms of acute respiratory infections do not subside after 3-4 days of drug therapy, it is imperative to visit a doctor. Strepsils combines well with various antipyretic and analgesic drugs. The high effectiveness and safety of the drug allows it to be considered the drug of choice in the treatment of diseases such as pharyngitis, glossitis, stomatitis (including aphthous), and gingivitis.
STREPSILS (tablets)
Now, knowing about the composition, I would not risk my immunity like that.
Having successfully recovered naturally, I completely forgot about the Strepsils lollipop tablets for a year; I discovered them yesterday in Vologda, when I had an annoying cough that I had been carrying on my feet since the time when the heating in the apartment had not yet been turned on. Yesterday the cough moved somewhere lower into the lungs, I couldn’t even sleep from the hysterical shaking of my entire insides.
Long after midnight I found Strepsils candies and ate 2 of them at once. It seemed to become a little easier, I fell asleep unnoticed. The next morning the cough appeared again, the pain shook the chest and stomach with cramps. I took another pill and felt a little better, and even went to work. The vacation is over, I didn’t go on sick leave, I can’t lose my salary - after all the summer travel, my wallet was completely empty.
I conclude that Strepsils lozenges still help with coughs a little quickly. But read on!
This is what the packaging of Strepsils plus lollipops looks like, or Strepsils Express, in our market it is called “Express” - as I understand it. And in Europe, these same lollipops are called Strepsils + Plus, like we have a similar spray, I barely understood the classification (Plus is not a spray at all, as in Russia), maybe it will be useful for someone when choosing a medicine abroad.
My packaging was in Greek, I didn’t even try to read the ingredients, but today I went to the Strepsils website in Russian and was surprised by the ingredients. It turned out that in Strepsils everything is not so harmless. Lidocaine! I remembered something from a visit to the dentist's office. After all, this is the same painkiller that I was injected with during tooth extraction. Freezing!
I must say that lidocaine is also indicated on the packaging; before it had never even occurred to me to read the composition of the lollipops.
The package contains 3 plates of 8 nuclear lollipops each.
These are seemingly harmless candies.
It is written that Strepsils fights bacteria and fungi. Maybe. I don’t presume to say that my symptoms just didn’t disappear, I just managed to fall asleep without a strong spasmodic cough. This is a plus, but the disease has not disappeared anywhere, so I won’t give it five stars, but nevertheless I will recommend it, since the lollipops still helped me. It also helped me as a decongestant.
There is also Strepsils Intensive. As I understand it, it is a little weaker than Strepsils Plus - Express. In any case, it is without lidocaine, but with flurbiprofen, and also only for adults. But Strepsils “Soothing action” and Strepsils “Children’s” are also available for children from 5 years of age. But will it have any effect? The active ingredients in it are the same as in Plus: dichlorobenzyl alcohol, amylmetacresol, of course, except for lidocaine.
But in general, I would not recommend, while recommending Strepsils now in my critical situation, any medications in general. Why do you need this without great need? The immunity that the body produces itself is more important, I think so. But if it’s completely unbearable, you still need to take something so that breathing doesn’t stop.
Its varieties
- Classic (original)
- With added vitamin C
- With added menthol and eucalyptus
- With the addition of lemon and mint
- With the addition of lemon and honey
- With a warming effect
It should also be noted that there are two complete dosage forms - lozenges and in the form of a spray. All medicines have a pleasant taste. There are certain varieties provided specifically for children.
