Prohibited during pregnancy
Prohibited during breastfeeding
Has restrictions for children
Has restrictions for older people
Has limitations for kidney problems
To treat bacterial infections, special drugs – antibiotics – are used. The antibacterial agent Suprax from the cephalosporin class is especially popular. It is produced in Jordan. The antibiotic Suprax is quite an expensive product, but in pharmacies you can find its analogues, which are much cheaper. They may have the same composition or have similar effects on the body.
Packaging of the drug Suprax
The medicine contains the active ingredient cefixime, a semi-synthetic antibiotic of the 3rd generation. It has a bactericidal effect against some gram-positive (streptococci) and gram-negative (for example, salmonella, proteus) pathogenic microorganisms. But most strains of staphylococcus are resistant to it.
The drug is used to treat infectious diseases that are caused by the activity of bacteria sensitive to the action of cefixime. It is often prescribed for infections of the ear, nose, throat, respiratory and urinary tract, and genitourinary system. It is forbidden to take the medication if the patient is intolerant to penicillin and cephalosporins.
Pharmacodynamics and pharmacokinetics
The antibiotic Suprax Solutab is semi-synthetic. Easily and quickly absorbed into the gastrointestinal tract. Antibiotics of this series inhibit the activity of cell membranes of harmful bacteria by inhibiting the synthesis of peptidoglycan. Active against gram-positive and gram-negative bacteria.
This group of antibiotics, when released into the blood plasma, binds to proteins (albumin). It is practically not metabolized in the organs and is excreted in the urine almost unchanged.
The price of the antibiotic is high, but this is fully justified by its effectiveness.
Suprax or Amoxiclav - which is better for pneumonia
Manufacturer: SANDOS, Slovenia
Release form: powder for suspension, tablets, dispersible tablets
Active ingredient: amoxicillin + clavulanic acid
Amoxiclav is an analogue of Supraxa tablets, which can be prescribed to children from 0 years of age in the form of a suspension. The product belongs to antibiotics and prescription drugs. It has a wide spectrum of action and antibacterial activity.
The active ingredients are quickly absorbed after oral administration. The degree of absorption is not affected by food intake. The product can be used during pregnancy and breastfeeding, but only as prescribed by a doctor.
The antibiotic Amoxiclav has the following indications:
- infections of the upper and lower respiratory tract, ENT organs;
- pathologies of the urinary and biliary tract, in gynecology, dermatology, which were caused by bacteria;
- infectious damage to bone and connective tissue;
- bacterial pathologies in dentistry.
For pneumonia, you can use both Suprax and its analogue Amoxiclav. This is explained by the fact that both drugs are highly effective in combating bacteria that cause inflammation of the respiratory tract.
Indications for use
According to the instructions, the drug is intended to treat inflammation caused by various infections, i.e. bacteria sensitive to the action of cefixime :
- respiratory tract infections: sinusitis , acute pharyngitis , agranulocytic tonsillitis , acute bronchitis , chronic pharyngitis , tonsillitis and bronchitis ;
- otitis media;
- urinary tract infections;
- shigellosis;
- uncomplicated gonorrhea (cervix, urethra).
Suprax or Azithromycin - which is better for pneumonia
Manufacturer: PHARMSTANDARD+, Russia
Release form: tablets, capsules
Active ingredient: azithromycin
Azithromycin is an inexpensive analogue of Suprax Solutaba, which is an antibiotic of the macrolide group. The drug is active against gram-positive bacteria. It is recommended to take according to the instructions to eliminate side effects from the body. The drug is quickly absorbed from the gastrointestinal tract. Should not be combined with food. It is excreted unchanged along with bile and urine.
A cheap analogue of Suprax 400 mg is prescribed to patients with the following pathologies and disorders:
- bronchitis, pneumonia;
- infections of the skin, soft tissues;
- otitis media, sinusitis, pharyngitis, tonsillitis;
- genitourinary system infections;
- borreliosis.
Side effects
According to the annotation:
- allergies: skin itching , urticaria - rarely, drug fever - very rarely;
- headache, tinnitus, dizziness;
- thrombocytopenia , bleeding, agranulocytosis - very rare;
- abdominal pain, indigestion, constipation , nausea, vomiting - often;
- impaired renal function, nephritis - rare.
Before use, you should consult your doctor.
Instructions for use of Suprax (Method and dosage)
How to take - before or after meals? Eating doesn't matter.
How to take the medicine? For adults and children weighing more than 50 kg, the daily dose is 400 mg of the drug in 1-2 doses. If the weight is from 25 to 50 kg - 200 mg per day at a time. The tablet is swallowed with plenty of water or a suspension is prepared (see instructions for use of the suspension). You can prepare sweet syrup for children.
The duration of treatment is prescribed by the doctor and depends on the severity of the type of infection, on average one or two weeks.
- for gonorrhea – 1 day;
- for mild forms of genitourinary infection – from 3 to 7 days;
- for angina - a course of 7-14 days is prescribed (for angina in children, the daily dose is reduced);
How to prepare Suprax suspension and how to dilute it correctly
Dissolve one tablet in a small amount of water and shake well. The suspension should be diluted in a glass or enamel container. Let the mixture stand for 5 minutes until the granules are completely dissolved. Shake before use.
Composition and release form
Capsules - 1 capsule:
- cefixime - 200/400 mg;
- excipients: colloidal silicon dioxide; magnesium stearate; carboxymethylcellulose; azorubine;
- capsule shell composition: titanium dioxide; dyes - D&C yellow 10, FD&C yellow 6, indigo carmine, FD&C blue; gelatin.
In a blister pack 6 pcs.; in a cardboard pack 1 package.
Granules for the preparation of suspension for oral administration - 5 ml:
- cefixime - 100 mg;
- excipients: sodium benzoate; sucrose; yellow resin; strawberry flavoring.
In dark glass bottles of 60 ml; in a cardboard pack 1 bottle complete with a dosing spoon.
Interaction
- blockers of tubular secretion (various diuretics, Allopurinol ) have the ability to delay the excretion of cefixime by the kidneys;
- when using the drug together with Carbamazepine , the level of concentration of the latter in the blood plasma may increase;
- significantly reduces the prothrombin index, enhances the effect of indirect anticoagulants;
- It is not recommended to take the drug simultaneously with antacids containing magnesium or aluminum hydroxide, because Absorption through the gastrointestinal tract will slow down.
Analogues of Suprax Solutab
Level 4 ATC code matches:
Cephosin
Lendatsin
Medakson
Loprax
Ceftriaxone
Cefixime
Lorakson
Sulperazon
Cefoperazone
Rocephin
Tsedex
Fortum
Ceftazidime
Cefotaxime
Cefix
Ceforal Solutab
Pantsef
Claforan
Cefodox
For an analogue of Suprax, the instructions for use must indicate that this is a third-generation cephalosporin drug and have cefixime as the main active ingredient. Often the price of analogues is slightly lower.
Common analogues of the antibiotic Suprax are:
- Suprax
- Cefixime
- Ixim Lupine
- Cemidexor
- Cefix
- Pantsef
The best analogue option for children is Ceforal Solutab.
Which is better: Pancef or Suprax?
The active ingredient in both antibiotics is the same. There is an opinion that allergies to Pancef are less common and its side effects are not so pronounced.
Suprax or Sumamed - which is better and stronger for pneumonia
Manufacturer: TEVA, Croatia
Release form: tablets, capsules, powder for suspension
Active ingredient: azithromycin
Sumamed is a cheap analogue of Suprax for children, which is prescribed from 6 years of age. The drug is a bacteriostatic antibiotic of the macrolide-azalide group. It has a wide spectrum of action, slows down the growth and reproduction of bacteria. The product has a detrimental effect on gram-positive, gram-negative, anaerobic, intracellular and other microorganisms.
The analogue of Suprax 400 mg Sumamed has the following indications:
- upper and lower respiratory tract infections;
- pathologies of ENT organs;
- infection process of the skin, soft tissues;
- pathologies of the genitourinary system;
- disorders in the gastrointestinal tract caused by Helicobacter pylori.
This drug is best used for pneumonia, as it is effective against pathogenic microorganisms that provoke this pathology.
Suprax for children
The dosage for children (weighing from 25 to 50 kg) is 200 mg per day, at a time. For pneumonia and bronchitis in children, the course of treatment is 7-14 days. The antibiotic can be simply swallowed with enough water or a suspension can be prepared. How to dilute Suprax Solutab is described above.
Reviews of Suprax for children
Reviews of the suspension for children are mostly positive, the drug is well tolerated, and adverse reactions from the gastrointestinal tract rarely occur.
Contraindications
The antibiotic has a number of contraindications, including:
- individual intolerance or hypersensitivity to the components of the drug;
- chronic renal failure;
- a history of severe allergic reactions to drugs from the group of cephalosporins and penicillins;
- lactation period;
- pseudomembranous colitis;
- children under 12 years of age (for capsules);
- children up to 6 months (for suspension);
- with caution: old age.
Reviews
Generally, doctors' reviews of the antibiotic are good. A high-quality and effective drug, well absorbed by patients.
Positive reviews of Suprax Solutab for cystitis . Recovery occurs quickly, side effects are rare.
If used frequently for the treatment of ENT diseases, the drug should not be used. However, the medicine has good reviews for sinusitis . It is convenient that you can prepare a suspension for children (or use 400 mg capsules).
Suprax during pregnancy and breastfeeding
Taking Suprax during pregnancy is prescribed only if there is a threat to the life of the mother. Moreover, this is possible only in the second and third trimesters. In the first trimester, taking Suprax can cause abnormalities or congenital deformities in the fetus.
Suprax during pregnancy
Suprax is contraindicated during lactation. If the drug is still prescribed, it is necessary to transfer the child to artificial feeding.
Price, where to buy
How much does the medicine cost? The price of tablets depends on the dosage form of the drug. On average, the cost of 7 dispersible tablets of 400 mg is about 800 rubles.
The price of Suprax for children (it is better to buy a ready-made suspension) is about 600 rubles per 30 ml.
The price of Suprax Solutab in Ukraine is about 250 hryvnia for 400 mg tablets, 7 pieces.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
Pharmacy Dialogue
- Suprax Solutab (dispersant tablet 400 mg No. 7) Menarini Manufachuring Logistics
RUB 1,041 order
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Pharmacy24
- Suprax Solutab 400 mg No. 10 tablets Menarini Menuf.Logist., Italy
330 UAH.order - Suprax Solutab 400 mg No. 7 effervescent tablets Menarini Menuf.Logist., Italy
215 UAH order
PaniPharmacy
- Suprax tablets Suprax solutab tablets. dispers. 400 mg No. 7 Italy, Menarirni Manufacturing
242 UAH order
- Suprax tablets Suprax solutab tablets. disp. 400 mg No. 10 Italy, Menarirni Manufacturing
349 UAH order
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Additional information about the drug
So, cephalosporins are antibiotics that are characterized by a wide spectrum of action; they are highly bactericidal and immune to beta-lactamases (bacterial enzymes that destroy the antibiotic, causing its action to become ineffective). In general, in some ways, cephalosporins are more effective than penicillins. And Suprax is based on third generation cephalosporins. And this is the first such antibiotic that can be taken orally. Suprax is based on cefixime. Cefixime affects the cell wall of the pathogen, inhibiting its formation.
Suprax inhibits the vital activity of streptococci, Haemophilus influenzae, Escherichia coli, Proteus, Salmonella, Citrobacter and gonococci. However, Suprax is powerless against Pseudomonas aeruginosa, most staphylococci, enterobacters and listeria. As for taking the drug, food does not affect its bioavailability in any way. Yes, it prolongs the period of reaching the maximum content in the blood and that’s all. Another good thing about Suprax is that you need to take it once a day. This is due to the half-life of the drug from the body. It takes a long time to come out. About 50% of the drug is excreted in the urine. And this is great because it is effective in treating urinary tract infections. However, it is better not to take it with diuretics, as the withdrawal of the drug is slowed down. In general, Suprax penetrates well to the site of infection. The main foci of infection with which Suprax interacts are the middle ear cavity, paranasal sinuses, tonsils, lungs, and bile ducts. If we rely on patient reviews about taking Suprax, they note a slight suppression of intestinal microflora. You can find Suprax in two dosage forms that are aimed at different age groups: 400 mg capsules for adult patients and granules for the preparation of a strawberry-flavored suspension 100 mg / 5 ml - 60 ml for children.
