TOP 13 cheap and effective analogues of the drug Creon for adults and children

Has restrictions during pregnancy

Allowed during breastfeeding

Allowed for children

Allowed for older people

Has limitations for liver problems

Has limitations for kidney problems

Creon is a drug that includes enzyme substances and is used to correct food digestion processes. The active substance is pancreatin. It consists of three groups of enzymes:

  • protease;
  • lipase;
  • amylase.

The main task of these substances is to catalyze the processes of digestion of proteins, fats and carbohydrates. There are several forms of this drug (drug), the main difference between them is the dosage of the active substance. In pharmacies you can purchase Creon 10,000, 25,000 and 40,000 units, as well as analogues of each of the forms given below. There is also a children's form of the drug Kreonchik for 5000 units. The drug is completely safe and can be used for all categories of patients.


Creon's action

The drug may be prescribed in the following cases:

  • chronic pancreatitis;
  • neoplasms of the pancreas;
  • surgical interventions on the gastrointestinal tract;
  • cholestasis;
  • biliary obstruction;
  • cystic fibrosis;
  • Shwachman-Diamond pathology;
  • malfunctions of the gastrointestinal tract of various ethologies;
  • cirrhotic processes;
  • duodenostasis and gastrostasis;
  • pathologies of the small intestine;
  • rehabilitation therapy after infectious lesions of the gastrointestinal tract;
  • normalization of pancreatic enzyme activity in elderly people;
  • obstructive processes in the bile ducts;
  • disorders of the intestinal microflora in newborns.

Pharmacodynamics

This enzyme preparation, as Wikipedia indicates, is intended to improve digestive processes. The pancreatic enzymes included in its composition promote the breakdown of proteins, fats and carbohydrates, leading to complete absorption in the small intestine. The main substance pancreatin is also the INN of the drug.

According to the abstract, the capsule shell easily dissolves in the stomach, resulting in the release of many mini-microspheres. Thus, mini-microspheres are mixed with intestinal contents, improving the distribution of enzymes within the intestine.

Inexpensive substitutes

The Russian market is sufficiently supplied with various representatives of the group of drugs that improve digestion. In order to figure out which one is suitable in your case, we suggest that you familiarize yourself in more detail with Creon analogues, which are cheaper.

Pancreatin

The drug belongs to the group of enzyme preparations that help normalize digestive processes. The tablets are based on pancreatin. Its action is aimed at catalyzing the processes of digestion of the main groups of nutrients. Subsequently, this helps to improve the absorption of these nutrients from the lumen of the small intestine.


The main active ingredient of the drug

Pancreatin is used in the following situations:

  • insufficiency of the excretory capacity of the pancreas;
  • chronic inflammatory processes localized in the gastrointestinal tract, accompanied by the development of dystrophic processes;
  • removal or irradiation of the digestive organs listed above;
  • as a component of combination therapy for flatulence and diarrhea;
  • failures in diet in patients who do not have pathologies in the functions of the digestive organs;
  • chewing disorder;
  • prolonged immobility and sedentary lifestyle.

The main contraindications are acute pancreatitis or relapse of chronic pancreatitis, individual intolerance to any components of the drug. The main difference between Pancreatin and Creon is that the latter has special protection for the active substance, which prevents its destruction in the stomach. Therefore, the components of the drug reach the lumen of the small intestine without loss of effectiveness.

Pancreazim

The drug is a representative of the pharmacological group of enzymatic agents that improve digestive processes. It contains pancreatin as the main component, and the auxiliary components are aerosil, crospovidone, magnesium stearate and others. They break down the molecular bonds of protein, fat and carbohydrate compounds, which facilitates their absorption in the small intestine.


Secretory function of the pancreas

Pancreazym is used for disorders of the secretory function of the pancreas, overeating. It is also used to combat the consequences of operations on the gastrointestinal tract and after treatment with chemotherapy. It is recommended to use the medication before or during meals. Side effects may include:

  • rash;
  • hyperuricosuria;
  • increase in uric acid content in blood plasma.

The medication is not recommended for use in case of inflammatory processes in the pancreas and in the presence of an allergy to its individual components. The effectiveness of Pancreazym is lower than that of Creon, since this drug is produced in the form of tablets that release enzymes more slowly than mini-microspheres.

Solizim

The medicine belongs to the category of enzyme-containing products that help normalize digestive processes. The main active ingredient in the composition is lipase. The enzyme substance is obtained from an extract of a special mushroom culture. Lipase helps hydrolyze fat particles in the intestines, which facilitates their further absorption and digestion. Solizim is used for:

  • hepatitis;
  • chronic pancreatitis;
  • enteritis;
  • gastritis;
  • enterocolitis;
  • going through the recovery period after operations on the gastrointestinal tract.


Action and indications for use of Solizym

The drug must be taken during or after a meal. No contraindications or side effects were identified during the drug study. The only thing you need to beware of is the appearance of increased individual sensitivity to individual components. Unlike Solyzyme, Creon is a drug containing three enzymes that can break down proteins and carbohydrates in addition to fats.

Somilaza

Included in a subgroup of medications containing enzymes, the action of which is aimed at improving digestion processes. Somilase has two main components - lipase and amylase, which catalyze the breakdown of fats and polysaccharides. It is used for disorders of the excretory function of the pancreas, in which the lipolytic and amylalytic ability of the organ suffers.


Pancreatic enzymes

The drug is also effective for other disorders of the digestive processes associated with inflammatory changes in the gastrointestinal tract. Somylase can also be used in cases of significant eating disorders and overeating. There were no side effects or contraindications other than individual intolerance to individual components of the drug. Unlike Creon, this medicine is not able to cope with impaired protein digestion.

Gastenorm Forte

The enzyme preparation includes pancreatin. It can relieve problems associated with the digestion and absorption of fatty, protein and carbohydrate foods. These conditions include:

  • inflammatory processes in different parts of the gastrointestinal tract;
  • disorder of exocrine activity of the pancreas;
  • physical inactivity;
  • binge eating;
  • problems with chewing food.


Indications for use of Gastenorm

To achieve the best therapeutic effect, the medicine is taken simultaneously with food. Among the side effects of the drug, the following were found:

  • development of an allergic reaction;
  • dyspeptic disorders;
  • hyperuricosuria;
  • hyperuricemia.

Gastenorm Forte is prohibited for use in cases of pancreatitis and intestinal obstruction. The drug has a similar effect to Creon, but the pancreatin contained in it has low activity.

Penzital

Refers to medicines that contain enzymes and promote food digestion. Its intake helps relieve the pancreas, prevents incomplete breakdown of nutrients, improves gastrointestinal function and eliminates excess gas formation. The drug must be taken before or immediately after a meal.


Release form of the drug

Contraindications include exacerbation of pancreatitis and hyperreactivity reactions to any component of the medication. Side effects may include stool disturbance, nausea, irritation of the oral mucosa and perianal area. There is also a risk of hyperuricemia and hyperuricosuria. It differs from Creon only in the release form: Penzital is sold in the form of tablets for oral use, and not in the form of mini-microspheres.

Mezim Forte

The medicine belongs to the pharmacological class of drugs containing biological catalysts. The active substance is pancreatin with low enzymatic activity. It prevents the development of pancreatic enzyme deficiency and has a pancreatoprotective effect.


Therapeutic effects of Mezim Forte

Used to prevent deficiency of pancreatic lipase, amylase and protease. Helps normalize digestive processes in the gastrointestinal tract, disturbed due to overeating and physical inactivity. Used enterally during or after meals. From the group of undesirable manifestations the following may develop:

  • allergic processes;
  • bowel disorders (various degrees of constipation or diarrhea);
  • nausea;
  • pain in the epigastric region;
  • increased levels of uric acid in urine or blood.

Unlike Creon, Mezim Forte contains low-active pancreatin in its structure. As a result, its therapeutic effect is less.

Indications for use of Creon

The main indications for use are:

  • carrying out replacement treatment for insufficient exocrine pancreatic function accompanying the following diseases: cystic fibrosis , chronic pancreatitis , pancreatectomy , pancreatic cancer , obstruction of the gastrointestinal tract due to neoplasms, Shwachman-Diamond syndrome , as well as in elderly patients;
  • symptomatic treatment of digestive disorders with: partial gastrectomy , total gastrectomy , biliary obstruction , liver cirrhosis , cholestatic hepatitis , terminal pathologies and excessive bacterial growth in the small intestine.

Contraindications of the drug

The medicine should not be used in the following cases:

  • for acute gastrointestinal diseases;
  • with high sensitivity of the stomach;
  • during individual intolerance.

Can pregnant women use the product? This is a fairly common question. However, the answer is negative due to the lack of reliable information.

Experts conducted studies only on animals, so it is difficult to say what effect the components of the medication will have on the fetus. Therefore, it can be used only when absolutely necessary.

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Creon capsules, instructions for use (Method and dosage)

Instructions for use Creon 10000 recommends prescribing them to small patients. In general, this drug of any quantity of units is taken orally. The dosage is selected individually and depends on age, severity of the disease and type of diet. It is usually recommended to take part of the medicine before meals, and the rest with food.

At the beginning of treatment, tablets are prescribed in a dosage of 10,000–25,000 units. When it is necessary to reduce steatorrhea and maintain optimal patient condition, the dose may be increased. In medical practice, patients can receive an average of 20,000–50,000 units of EP lipase.

During the treatment of cystic fibrosis, the dosage is determined depending on the weight. For example, when treating small patients under 4 years of age, 1000 lipase units per kg of weight are prescribed, and over 4 years of age, 500 lipase units per kg of weight with each meal. For many patients, the daily dosage should not exceed 10,000 units per 1 kg of weight.

Instructions for use Creon 25000 recommends taking it in the treatment of other conditions that may be accompanied by exocrine pancreatic insufficiency. In this case, the dose is set taking into account the individual characteristics of the patient, for example, how much digestion is impaired, how much fat is contained in the food, and so on.

Instructions for use of Creon for children contain a detailed description of how to give it to children with difficulty swallowing. To use this drug for children, the capsules must be carefully opened. The internal contents are mixed with liquid or food that does not require chewing. It must be remembered that such mixtures cannot be stored, so take them immediately after they are prepared. It is forbidden to crush or chew mini-microspheres and add them to acidic foods - this can destroy their shell, which protects them from the effects of gastric juice.

Instructions for use Creon 40000 recommends taking this drug for adult patients. Its dosage also depends on the severity of the disease and the personal characteristics of the patient. The duration of use must be determined by the attending physician.

Use of the medication

The medicine is available in the form of capsules, which must be taken orally with a large volume of water.

Typically, experts recommend taking two capsules at a time.

One of them before meals, and the second during meals. If the patient has difficulty swallowing, carefully open the capsule and dilute its contents in liquid, then mix well and drink.

The exact dosage and duration of therapy are prescribed exclusively by the doctor, after the diagnosis has been established.

special instructions

There have been cases when patients treated for cystic fibrosis received pancreatin in high dosages, which caused colitis , strictures of the cecum and ileum.

For this reason, it is necessary to monitor the dose, especially when Creon 40000 is prescribed. It is also necessary to monitor the appearance of any symptoms and changes that occur in the abdominal cavity. In addition, you should immediately find out how to take Creon to 10,000 adult patients and not exceed its dosage.

Pangrol or Creon: which is better?

Pangrol is considered one of the highest quality analogues. And all thanks to the similar composition and amount of active ingredients. Typically the drug is prescribed for the following diagnoses:

  • treatment of chronic pancreatitis;
  • cystic fibrosis;
  • pancreatic cancer.

Often, specialists prescribe the drug after surgical interventions for speedy rehabilitation. Pangrol helps to efficiently digest heavy foods and fights intestinal infections.

The release form is in the form of capsules, which guarantees high-quality absorption and delivery of the necessary components to the source of the problem.

Contraindications:

  • acute pancreatitis;
  • individual intolerance;
  • allergy to components.

Adverse reactions may occur, including diarrhea, vomiting, and rash.

Manufacturers of high-quality analogues are Italy and Germany, so the drug cannot be called cheap. Its price in many pharmacies across the country reaches 260 rubles.

Thus, both components have the same properties. The only difference is that the effect of Pangrol occurs after 45 minutes, when its analogue only needs 30 minutes.

Creon for children

An enzyme preparation is prescribed to children when they need to improve digestion. The recommended daily dosage of Creon 10,000 for children is divided into several parts and taken with each meal.

When prescribing it, parents need to immediately find out from the doctor how to take Creon for children, since the dose is prescribed taking into account the baby’s weight.

It should be noted that reviews for the child are very ambiguous. Some mothers report the effectiveness of the capsules, but there are also reviews about the uselessness of this medicine.

Creon for babies

When this drug is prescribed to children, many parents immediately have questions: what is Creon and what is it taken for? It is known that the gastrointestinal tract of newborns develops over a certain period of time. Therefore, even small deviations in the diet for infants can cause problems.

Also, mothers begin to worry about how to give capsule medicine to their infant? In fact, the pediatrician explains all this in detail and describes the instructions for the drug. It should be noted that Creon 10000 is usually prescribed for newborns, indicating the dosage, regimen and duration of therapy.

Reasons to prescribe capsules for newborns are:

  • constant colic;
  • constipation or diarrhea with particles of undigested food;
  • bloating.

By the way, reviews from parents show that the question of how to give this medicine to a baby is not a problem at all. Many mothers are confused by the effect of the drug, since its effectiveness is not always evident.

Creon or Mezim: which is better?

The main active substance of Mezim is pancreatin; in addition, the medicine contains lipases, macrogol, amylases and proteases.

However, the concentration of all components here is small, so for the treatment of serious diseases the doctor prescribes Creon.

The drug is produced in Germany, where the secretion of the pig's pancreas is used to create it. The medicine is available in the form of tablets, each of which is coated.

Mezim has an enzyme-containing agent. However, due to the release in tablets, they slightly lose their effectiveness. The reason for this is early solubility in gastric juice, which does not allow the components to reach their target in full. The same cannot be said about Creon, which is available in capsules.

Mezim should not be used for the following ailments:

  • with acute inflammation of the pancreas;
  • with exacerbation of pancreatitis;
  • individual intolerance.

In terms of contraindications, both drugs are identical. When talking about efficiency, it is impossible to clearly appoint a leader.

Experts recommend using Mezim for mild forms of complications. Moreover, it has a significantly lower cost. In all other situations, preference should be given to a stronger drug.

Analogues of Creon

Level 4 ATC code matches:
Digestin

Pancitrate

Mezim

Festal

Pankreoflat

Pancreazim

Enterosan

Panzinorm Forte

Panzinorm

Micrasim

Enzistal P

Pancreatin


Penzital

Pangrol

Hermital

Abomin

The main analogues of Creon 10000 and other units:

  • Panzinorm
  • Micrasim
  • Penzital
  • Pangrol
  • Mezim
  • Pancreazim
  • Gastenorm
  • Enzistal
  • PanziCam
  • Pancreatin

However, this does not mean that each of them is an equivalent substitute.

It should be noted that the price of analogues can be very different and cannot incline towards the purchase of one or another medicine. The question of what can replace treatment should be clarified with a doctor. Especially when the medicine is selected for children under one year of age.

Creon or Pancreatin - which is better?

Despite many similarities, each of these drugs has significant differences. But if you know what the difference is, then you can make the right choice when buying a medicine.

If we compare how Creon differs from Pancreatin , then the first is the form of release. Pancreatin is available in tablets. The second difference is the concentration of the active substance, which in Pancreatin is presented in arbitrary content.

The effect of drugs is also different - Pancreatin already acts in the stomach and therefore does not fully perform its function, which is why it is considered less effective. Although its cost is much lower.

Thus, based on these data, each patient will be able to decide which drug to choose.

Hermital or Creon - which is better?

The compositions of these drugs are quite similar, but Ermital is less effective due to the type of active ingredient. Creon mini microgranules easily mix with the contents of the stomach, significantly improving physiological digestion, while other products have a somewhat delayed effect.

Which is better: Creon or Micrasim?

These products are almost identical in everything, but they differ in the dosages of their components.

For example, Micrasim contains 320 mg of pancreatin. In addition, it is a domestically produced medicine and is cheaper.

Therefore, when prescribing this drug, it is important to take into account the high content of the enzyme, since such a difference is noticeable and can lead to complications in the digestive tract.

Creon or Panzinorm - which is better?

Another absolute analogue is Panzinorm . It is produced by the KRKA brand from Slovenia. This medicine is also used in the treatment of enzyme deficiency.

It is believed that each of them has the same effectiveness, and which drug is suitable for treatment, you need to choose yourself, but still on the recommendation of a doctor.

Average prices in Russia for the drug and its analogues

In order to understand the average cost of the drug and its analogues, we suggest that you familiarize yourself with the following list of drugs presented in the table. Before using any of the listed drugs, you should consult your doctor.

Trade name of the drugPrice
1Creon290 rub.
2Mezim-Forte73 rub.
3Micrasim244 rub.
4Pancreazim50 rub.
5Pancreatin45 rub.
6Penzital60 rub.

The difference in cost is based on the dosage form of the active substance. Cheaper analogues of Creon are presented in the form of tablets, therefore they contain enzymes in powder form, which can be pressed. This supply reduces the cost of production and reduces the cost of the final product.

In Creon, enzymes are mini-microspheres, which are subsequently placed in a capsule. This production method is more expensive, but this drug is more effective in use than its analogues. This is due to the fact that minimicrospheres with enzymes are released from the shell faster, and the concentration of the main substance reaches its maximum in much less time.

Reviews about Creon

This drug is quite popular and is discussed on various forums. Reviews about Creon 10000 are especially common, which is prescribed to young children suffering from digestive disorders. Although many mothers do not understand what Creon tablets are for, they try to treat their baby with it.

It is interesting that reviews of Creon 10000 for infants are markedly ambiguous - while some mothers report that the treatment helped them quickly get rid of problems, others call it the most useless medicine. However, it does not cause harm to the child.

Patients are also actively discussing Creon 25000, which is prescribed to patients with digestive system disorders. Numerous reviews of Creon 25000 on forums are also very mixed. While some take it for complex disorders of the digestive system, most take it in cases where problems arise with digesting “heavy” food. One way or another, this allows you to improve the condition of insufficiency of exocrine pancreatic function and other disorders.

By the way, there are reports that some adult patients refuse to use this drug due to the fact that it is produced from pork pancreas. In rare cases, you can find stories about the undesirable effects of this drug, in the form of heaviness and discomfort in the stomach, pain in the gall bladder.

Undoubtedly, patients for whom this drug brought the desired effect and helped reduce the manifestations of severe diseases of the digestive system are not going to stop taking it. An important point of the therapeutic course is to follow a diet with healthy foods and nutrition in normal amounts. With this approach, you can maintain your own health and prevent the development of complications.

Medicines for ulcers and gastritis

Therapy for these diseases should be prescribed by a doctor, taking into account the existing symptoms. These pathologies are interrelated, so the drugs for their treatment are similar. Most often, their action is aimed at neutralizing H. Pylori. Tablets prescribed for abdominal pain can be divided into 4 categories.

Antibiotics

Gastroenterologists carefully select antibiotic treatment. It is necessary to compare the risks of side effects and the beneficial effect. Most often, a two-week course of antibiotic therapy is the only way to eradicate H. Pylori.

CLARITHROMYCIN TAB. P/P/O 250MG No. 14
AMOXICILLIN CAPS. 250MG No. 16
AMOXICILLIN CAPS. 500MG No. 16
AMOXICILLIN TAB. 500MG No. 20
METRONIDAZOLE TAB. 250MG No. 40

Proton pump inhibitors

The action of these medications is aimed at blocking the release of bile acid, which accelerates the healing of ulcers.

Do not forget that using inhibitors in large dosages for severe stomach pain is too risky. Leukopenia, nervous disorders, and myalgia are highly likely to develop.

OMEZ DSR CAPS. MODIF. HIGH 30MG+20MG No. 30
OMEZ CAPS. 20MG No. 30
OMEZ CAPS. K/R 10MG No. 10
OMEZ CAPS. K/R 40MG No. 28
OMEPRAZOLE CAPS. 20MG No. 30
EZOMEPRAZOLE TAB. K/R P/O 20MG No. 28
EZOMEPRAZOLE-SZ CAPS. K/R 40MG No. 28
OMEVEL CAPS. K/R 20MG No. 30

H-2 histamine receptor blockers

Their action is aimed at reducing acid production in the stomach. Under the influence of drugs, acid is formed in minimal quantities, which does not allow the ulcer to grow.

RANITIDINE TAB. P/P/O 150MG No. 30

Antacids

They neutralize stomach acid, reducing pain. But experts emphasize that antacids quickly eliminate pain without getting rid of its cause. That is, these drugs do not promote healing of ulcers. In addition, they are often produced in the form of suspensions, which can cause nausea, vomiting, and constipation.

PHOSPHALUGEL GEL FOR ORAL TAKEN 16G No. 20
ALMAGEL A SUSP. D/ORAL 10ML No. 10
ALMAGEL A SUSP. FOR ORAL USE 170ML COMPLETE WITH MEASURING SPOON
MAALOX SUSP. D/ORAL 15ML No. 30
MAALOX SUSP. D/ORAL 15ML No.6
MAALOX SUSP. D/ORAL 250ML
MAALOX TAB. CHEW. №10 B/SUGAR
MAALOX TAB. CHEW. No. 20
GASTAL TAB. D/RASSAS. No. 12
GASTAL TAB. D/RASSAS. No. 12 MINT
GASTAL TAB. D/RASSAS. No. 30
GASTAL TAB. D/RASSAS. No. 60
RENNIE TAB. CHEW. 680MG+80MG No. 12 ORANGE
RENNIE TAB. CHEW. 680MG+80MG No. 24 ORANGE
RENNIE TAB. CHEW. 680MG+80MG №24 MENTHOL
RENNIE TAB. CHEW. 680MG+80MG No. 48 ORANGE
RENNIE TAB. CHEW. B/SAKH. 680MG+80MG No. 12 MINT
RENNIE TAB. CHEW. B/SAKH. 680MG+80MG No. 48 MINT
GAVISCON DOUBLE ACTION SUSP. FOR ORAL USE 10ML No. 12 MINT
GAVISCON FORTE SUSP. D/ORAL 10ML No. 12 D/PREGNANT. MINT

Creon price, where to buy

The price of Creon depends on the number of units and the number in the package.

You can buy Creon 10000 tablets in Moscow at a cost of about 300 rubles for 20 pcs. This is the medicine chosen for children.

The price of Creon capsules is 25,000 for 20 pieces. is approximately 600 rubles.

Creon price 40,000 for 50 pcs. starts from 1400 rubles.

The price of Creon 10000 in Ukraine is about 100 UAH.

  • Online pharmacies in RussiaRussia
  • Online pharmacies in UkraineUkraine
  • Online pharmacies in KazakhstanKazakhstan

ZdravCity

  • Creon 25000 caps.
    ksh/sol. 25000 units 50pcs JSC Veropharm 1292 RUR order
  • Creon 10000 caps. ksh/sol 150 mg 20 pcs Abbott Laboratories GmbH

    RUB 284 order

  • Creon 25000 caps. ksh/sol 300 mg 20 pcs Abbott GmbH

    601 rub. order

  • Creon Micro included with measure spoon porridge granules/sol. 5000IU 20gAbbott GmbH

    RUB 1,399 order

  • Creon 10000 caps. ksh/sol. 10000 units 50pcs JSC Veropharm

    RUR 643 order

Pharmacy Dialogue

  • Creon capsules 10000 units No. 20Abbot Laboratories

    RUB 334 order

  • Creon capsules 25000 units No. 50Abbot Laboratories

    RUB 1,362 order

  • Creon capsules 40000 units No. 50Abbot Laboratories

    RUB 1,447 order

  • Creon (caps. 25000 units No. 20)Abbot Laboratories

    RUB 613 order

  • Creon capsules 10000 units No. 50Abbot Laboratories

    RUR 706 order

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Pharmacy24

  • Creon 10000 150 mg N20 capsules Abbott Laboratories GmbH, Nimetchina
    102 UAH.order
  • Creon 25000 300 mg N20 capsules Abbott, Germany

    271 UAH order

  • Creon 25000 300 mg N100 capsules Abbott Laboratories GmbH, Nimecchina

    1269 UAH. order

PaniPharmacy

  • Creon 25,000 capsule Creon 25,000 capsules. 300 mg blister. No. 20 Germany, Abbott Lab.

    279 UAH. order

  • Creon 10,000 capsule Creon 10,000 capsules. 150 mg No. 20 Germany, Abbott Lab.

    102 UAH order

  • Creon 10,000 capsule Creon 10,000 capsules. 150 mg blister. No. 20 Germany, Abbott Lab.

    116 UAH order

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