Relief is a series of expensive drugs designed to treat hemorrhoids and eliminate its symptoms: pain, bleeding, itching. Despite their advantages, widely advertised suppositories and ointments are not affordable for everyone. Cheap analogues of Relief will save the situation. Let's take a closer look at them, how they differ and what their advantages are.
Suppositories for the treatment of hemorrhoids
Relief is a series of antihemorrhoidal medications, including 4 types of suppositories and ointments:
- Relief;
- Relief Ultra;
- Relief Pro;
- Relief Advance.
The cost of the medicine is 320-500 rubles. depending on the specific name and dosage form.
How to eliminate constipation and get rid of the need to use the drug Relief for hemorrhoids.
Relief or Relief Advance, -Ultra, -Pro - which is better?
The difference between the drugs of the Relief brand lies in the set of active ingredients; accordingly, they differ in the effect they have. They are united by a common area of application - hemorrhoids and injuries in the anus.
Comparative characteristics of the composition, pharmacological action and scope of application are described in the table:
A drug | Active ingredients | Therapeutic effect | Indications for use |
Relief, suppositories and ointment | Phenylephrine hydrochloride | Vasoconstrictor, reducing swelling and itching. | Hemorrhoids, anal fissures and itching. |
Relief Advance, suppositories and ointment | Benzocaine | Site anesthetic. | Hemorrhoids, anal itching. |
Relief Ultra, candles | Zinc sulfate monohydrate + Hydrocortisone acetate | Healing, anti-inflammatory, vasoconstrictor, antiallergic. | Hemorrhoids, anal fissures and itching, proctitis, eczema and dermatitis of the anal area. |
Relief Pro, candles and cream | Fluocortolone pivalate + Lidocaine hydrochloride | Anti-inflammatory, vasoconstrictor, antiallergic and local anesthetic | Hemorrhoids, proctitis, eczema in the anal area. |
Forms of release, structural analogues, prices
The medicine (hereinafter referred to as the drug) is available in the form of ointments and suppositories. At the same time, anal suppositories are a group of medications widely used in the field of proctology when diagnosing injuries or inflammatory processes in the lower rectum:
- Relief Ultra - used in severe stages, when hemorrhoids are accompanied by an increase in body temperature. It is not recommended to use for a long time.
- Relief Pro. Promotes tissue restoration. Effective in the first and second stages of the disease. The product can be used for a long time.
- Relief Advance. Prescribed for chronic hemorrhoids. Relieves pain syndrome.
Indications for the use of various forms of Relief
These medications are structural analogues of the original drug. They are based on the same substance and have a similar mechanism of action.
Relief is popular due to its effectiveness and high quality. However, modern companies produce no less high-quality drugs, the price of which is much lower. To choose an effective substitute, you must consult your doctor.
See also:
Instructions for use and analogues of the drug Bezornil
Relief's analogues
You can replace Relief suppositories with any local medications for hemorrhoids. There are many analogues cheaper than Relief, differing in composition and manufacturer, but used for hemorrhoids and similar diseases.
A list of such analogues is presented in the table
Analogue | Active substance | Average price, rub. | Country of origin |
Relief, suppositories and ointment | Phenylephrine hydrochloride | 350 | Italy/Greece |
Relief Advance, suppositories and ointment | Benzocaine | 450 | Italy/Greece |
Relief Ultra, candles | Zinc sulfate + Hydrocortisone acetate | 500 | Italy |
Relief Pro, candles and cream | Fluocortolone pivalate + Lidocaine hydrochloride | 400 | Italy |
Procto-Glyvenol, suppositories and cream | Tribenoside + Lidocaine | 400 | Ireland/Switzerland |
Natalsid | Sodium alginate | 400 | Russia |
Proctosan, suppositories | Bufexamac + Bismuth subgallate + Lidocaine hydrochloride | 350 | Germany |
Posterizan, suppositories and ointment | Microbial cells of Escherichia coli killed by phenol | 400 | Germany |
Hepatrombin G, suppositories and ointment | Heparin sodium + Prednisolone + Lauromacrogol 600 | 200 | Serbia |
Nigepan, candles | Heparin sodium + Benzocaine | 190 | Russia |
Anuzol | Belladonna extract + bismuth compounds + Zinc sulfate | 80 | Russia |
Heparin ointment | Sodium heparin + Benzocaine + Benzyl nicotinate | 60 | Russia |
Proctosedyl, ointment and rectal capsules | Benzocaine + Butamben + Hydrocortisone + Framycetin + Esculoside | 220 | India |
Aurobin, ointment | Prednisolone capronate + Lidocaine hydrochloride + Dexpanthenol | 350 | Hungary |
Bezornil, ointment | Zinc carbonate + Artificial musk and bezoar + pearl and amber | 450 | China |
Anestezol, suppositories | Benzocaine + Bismuth subgallate + Racementol + Zinc oxide | 80 | Russia |
Methyluracil, suppositories and ointment | Dioxomethyltetrahydropyrimidine | 100 | Russia |
Hepazolon | Heparin + Prednisolone + Lidocaine | 350 | Russia |
Detralex | Diosmin + Hesperidin | 650 | France |
Nigepan
Manufacturer: NIZHFARM, Russia
Release form: rectal suppositories
Active ingredient: Heparin sodium + Benzocaine
Domestic Nigepan suppositories are available only by prescription, and are an analogue of Relief for hemorrhoids, since they are used as an anticoagulant, anti-inflammatory and local anesthetic.
Anuzol
Manufacturer: NizhFarm, Biosintez, Russia
Release form: rectal suppositories
Active ingredient: Belladonna leaf extract + Bismuth tribromophenolate and Bismuth oxide complex + Zinc sulfate
Anuzol is closer in composition to Relief Ultra; the analogue has a drying and astringent effect, but instead of a glucocorticoid, it contains belladonna extract, which has an antispasmodic effect. This analogue can be used alternately with Relief or drugs with a different mechanism, for example, sea buckthorn suppositories.
Proctosedyl
Manufacturer: Sanofi, India
Release form: ointment, rectal capsules
Active ingredient: Benzocaine + Butamben + Hydrocortisone + Framycetin + Esculoside
Proctosedyl is a cheaper analogue of Relief suppositories for hemorrhoids, but at the same time it has a wider composition, due to which it has an anti-inflammatory, local anesthetic, antipruritic and antibacterial effect at the same time. Used for hemorrhoids and itching in the anus.
Heparin ointment
Manufacturer: NIZHFARM, Green Dubrava, Altaivitamins, Russia
Release form: ointment for external use
Active ingredient: Sodium Heparin + Benzocaine + Benzylnicotinate
Heparin ointment is effective for thrombophlebitis, and for injuries and hematomas, and can be used as an ointment for hemorrhoids.
As an analogue of Relief, it has an antithrombotic and local anesthetic effect, relieves swelling and inflammation at the sites of application.
Bezornil
Manufacturer: Mainlong, China
Release form: ointment for rectal and external use
Active ingredient: zinc carbonate + artificial musk and bezoar + pearls and amber
A Chinese analogue that has an original composition of natural and artificial minerals, which together has an antiseptic, decongestant, hemostatic, astringent and analgesic effect.
Used for anal itching and anal fissures.
Aurobin
Manufacturer: Gedeon Richter, Hungary
Release form: ointment for external and rectal use
Active ingredient: Prednisolone capronate + Lidocaine hydrochloride + Dexpanthenol
The Aurobin analog has an anti-inflammatory, anti-edematous and antipruritic effect, thanks to the main component Prednisolone.
Dexpanthenol has a healing effect, Lidocaine is a local anesthetic.
The main indication for the use of this ointment is anal itching.
Anestezol
Manufacturer: NizhFarm, Russia
Release form: rectal suppositories
Active ingredient: Benzocaine + Bismuth subgallate + Racementol + Zinc oxide
Anestezol is an inexpensive analogue of Relief suppositories for hemorrhoids; it contains an optimal complex of active ingredients, thanks to which it is used for external hemorrhoids and other inflammatory diseases of the rectum.
Methyluracil
Manufacturer: NizhFarm, Biokhimik, Dalkhimfarm, Russia
Release form: ointment for external use and rectal suppositories
Active ingredient: Dioxomethyltetrahydropyrimidine
Synonyms: Meturacol, Stizamet
Methyluracil has a regenerative effect and is used as a healing agent for diseases accompanied by damage to both the skin and mucous membranes, and internal organs.
Methyluracil can be used as an analogue of Relief Pro or Ultra ointment, as an antihemorrhoidal agent.
Hepazolon
Manufacturer: Altfarm, Russia
Release form: rectal suppositories
Active ingredient: Heparin + Prednisolone + Lidocaine
Gepazolon is an analogue of Relief Pro suppositories, since its composition is closest to this drug; in addition, it also contains heparin, which prevents blood coagulation in hemorrhoids and has an anti-inflammatory and decongestant effect.
Detralex
Manufacturer: Servier Laboratories, France
Release form: film-coated tablets
Active ingredient: Diosmin + Hesperidin
Synonyms: Detravenol, Stimulven
Detralex has a venotonic and vascular-strengthening effect, reduces capillary permeability, reduces the distensibility of veins and venous stagnation.
The Detralex analogue is taken orally. It is good to use it with any Relief substitutes, not as an analogue, but as a complex therapy. The drug is also used for other diseases accompanied by venous insufficiency, for example, varicose veins.
Detralex is especially effective for acute attacks of hemorrhoids.
Advantages of Relief drugs over similar antihemorrhoidal drugs
When trying to find generics of drugs, we found out that the German chemical and pharmaceutical corporation Bayer is rapidly developing subsidiaries around the world. Therefore, Canada, Italy and other countries are indicated on the Relief packaging. CJSC Bayer operates in Russia.
Since 2008, Bayer Health Care has purchased core assets for the production of over-the-counter drugs from the American company Sagmel from Chicago. As part of them, the rights to release the Relief series were transferred to Germany. Therefore, all products in the series can be considered generics (the possibility of production under the previous brand is lost).
Was the deal worth the economic gain? The drugs still do not have complete substitutes; in terms of medicinal properties and form, they differ from other drugs by the power of shark oil with valuable natural components.
The natural product has been used for medicinal and cosmetic purposes since the time of Hippocrates. Pronounced properties to counteract inflammation and infection (antiseptic + enhancer of local immunity), accelerate tissue restoration, wound healing of erosions, rectal fissures. The fat contains essential amino acids for tissue nutrition, a complex of vitamins and microelements, squalene, antioxidants, omega 3, and immunostimulants. Chemicals have been added to various forms of the series to enhance effectiveness. Let's consider the advantages, impact on indications for use and cost of the funds.
Relief (ointment) - in addition to shark liver fat, contains phenylephrine - a substance that constricts blood vessels, has antipruritic properties, relieves swelling during inflammation, stops bleeding, activates local immunity, and causes blood flow from hemorrhoids. Suitable for long-term use in stages I–II of hemorrhoids, for prevention. Not contraindicated during pregnancy and after childbirth.
Relief (suppositories) - work better for internal hemorrhoids. Properties are similar to ointment. Effective in chronic form. Relieves weeping and discharge from the anus. Contraindications are: thyrotoxicosis, increased sodium levels in the blood, impaired intracardiac conduction, granulocytopenia. Prices range from 623 to 762 rubles per package.
Relief Advance (in the form of ointments, suppositories) is prescribed if the clinical course of the disease is dominated by pain. The shark oil base contains benzocaine. Contraindicated in pregnancy, in the treatment of children under 12 years of age, in case of hypersensitivity, suspected acute thrombosis. Due to the effect on hematopoiesis, the leukocyte count is always checked before use. Reduces the number of granulocytes. The ointment costs 435 rubles, suppositories - 498.
Relief Pro (in the form of a cream, suppositories) - the chemical substances in the composition include fluocortolone and lidocaine. Both components inhibit the process of exudation, accumulation of neutrophils, proliferation of granulations and infiltration. The main purpose is to relieve bleeding when nodes are damaged. Inflammation, pain, burning sensation and itching are also suppressed. The action begins 20–30 minutes after administration. Contraindications concern: pregnancy in the first trimester, hypersensitivity to components, infection. Women after the 14th week of pregnancy and during lactation are prescribed with caution.
The cream has a softer consistency than suppositories, is quickly absorbed, and is sold with an applicator for insertion into the anus. Use for more than a month can cause the appearance of stretch marks, telangiectasia, and areas of atrophy on the skin around the anus.
The price of the cream is 335 rubles, the candles are 386 rubles.
Relief Ultra (suppositories, ointment, cream) - the anti-inflammatory effect is enhanced by zinc sulfate and hydrocortisone (a steroid hormonal substance). Prescribed for intense signs of inflammation with fever. Usually recommended in short courses. At initial manifestations and between courses, Relief is indicated. In addition to pregnancy, the instructions indicate contraindications: any infection (especially fungal, tuberculosis), diabetes, neoplasms, thrombosis, allergies. Not recommended if you have a tendency to hypertension or problems with difficulty urinating. Cream in a 10 g tube costs 278–293 rubles, 10 candles - 564 rubles, ointment - 443 rubles.
From the description given, we can conclude that drugs from the Relief series are best used on the recommendation of a doctor. Not everyone is suitable for long courses. Contraindications should be taken into account. An important distinguishing feature is the relative high cost.
Natalsid or Relief – which is better?
Manufacturer: NizhFarm, Russia
Release form: rectal suppositories
Active ingredient: Sodium alginate
Analogue Natalsid contains a natural polysaccharide, which is obtained from seaweed. Has a hemostatic, anti-inflammatory and healing effect. Used for hemorrhoids accompanied by bleeding.
The advantage of this analogue of Relief suppositories is the possibility of its use during pregnancy. Reviews from doctors indicate the high effectiveness of the drug.
Substitutes in the form of candles
Also available to customers is a large selection of Relief substitutes, which are available in the form of rectal suppositories. Their cost is lower than the original, and the method of application and mechanism of influence are similar.
The list of effective substitutes includes:
- Natalsid;
- Anestezol;
- Sea buckthorn candles;
- Hemorrhoids;
- Methyluracil.
The selection of a substitute is carried out with the permission and under the supervision of a doctor.
Anestezol
A medicine from the group of local anesthetics is developed on the basis of menthol, zinc oxide, bismuth subgallate and benzocaine. It has pronounced analgesic, antiseptic, astringent and drying properties. In the organic field, the medication is used to eliminate the symptoms of various pathologies of the anus. Eliminates signs of inflammation, alleviates the course of diseases that lead to damage to the mucous membrane.
The list of indications for use includes:
- Mild form of internal hemorrhoids.
- External hemorrhoids.
- Thrombosis of hemorrhoids.
- Microcracks of the anus.
Mechanism of action of Anestezin
Anestezol can be used as an independent agent or as part of complex therapy.
It is not recommended to use suppositories for the treatment of children under 12 years of age, pregnant women, or during lactation. Contraindications also include hypersensitivity to the main components.
The most common side effects include itching and burning at the site of contact between the suppository and the colon. In some cases, the medicine may cause diarrhea.
Before administering the drug, you should have a bowel movement. If the patient cannot do this on his own, it is necessary to give an enema. Immediately before administration, you should wash your hands thoroughly. The manufacturer's instructions indicate that one or two candles can be used per day.
The duration of treatment depends on the severity of the pathology and is determined by the attending physician. With long-term use, it is important to periodically check the general blood picture because there is a risk of developing methemoglobinemia.
Compared to Relief, the analogue has a wider range of effects, as it is developed on several substances. In addition, these candles are much cheaper.
Natalsid
Another effective substitute for Relief is a representative of the medicinal group of hemostatics for topical use - Natalsid. The main component is sodium alginate. The drug exhibits anti-inflammatory, hemostatic, and reparative effects. Promotes wound healing and stops bleeding. Restores damaged tissue areas.
The active component of the drug is a natural polysaccharide found in sea brown algae. Characterized by hemostatic and reparative properties.
Conditions for which the medicine is prescribed:
- Chronic hemorrhoids, which may be accompanied by bleeding.
- Chronic anal fissures.
- Inflammation in the postoperative period.
- Proctosigmoiditis.
The drug is intended for local use.
This product is one of the safest. Contraindications include hypersensitivity to components and childhood. Prescribed for the treatment of patients over 14 years of age.
According to the instructions, the suppository should be administered after an enema or spontaneous bowel cleansing. It can be slightly moistened with water beforehand. Recommended dose – 1 suppository 1-2 times a day. This dosage is suitable for adults and adolescents. The duration of the therapeutic course should not exceed two weeks.
If used incorrectly or allergic to the components, negative reactions may occur in the form of skin rash, burning, itching, peeling.
Natalsid exhibits a pronounced hemostatic effect. During contact with bleeding tissues, it helps stop bleeding. The original remedy helps to narrow blood vessels and increase the tone of vascular tissue. Medicines are based on different substances.
Hemorrhoids
The drug, intended for the treatment of hemorrhoids, contains extracts of chamomile, belladonna, rhizomes of erect cinquefoil, gorse, horse chestnut, and millennial. The combined drug has bactericidal, astringent, antispasmodic and anti-inflammatory characteristics. In the presence of cracks, inflammatory changes are eliminated.
Composition of the drug
The medication is used for symptomatic treatment of internal or external hemorrhoids, itching, pain or anal fissures. The medicine is also effective for chronic proctitis and inflammatory processes. Often LP is prescribed after sigmoidoscopy to prevent the development of complications.
Despite the fact that the medicine was developed using raw materials of plant origin, experts identify a number of conditions in which its use is prohibited. The list of contraindications includes:
- individual intolerance to extracts;
- formations in the colon;
- glaucoma;
- granulocytopenia;
- thyrotoxicosis;
- renal failure;
- urinary system disorders;
- acute bleeding;
- diseases of the cardiovascular system.
During pregnancy, drugs can cause abortion or premature birth.
Benefits of Hemorol
Use with increased caution is allowed in old age, with Down syndrome, cerebral palsy, traumatic brain injury, liver failure, prostate hypertrophy.
Negative reactions include: dizziness, tachycardia, pain in the head, increased intraocular pressure, constipation, a feeling of dry mouth, arterial hypertension.
The initial daily dose for mild pathology is 1 suppository. If a severe form is diagnosed, the dose should be increased to 2-3 suppositories per day. It is not recommended to use the medication for longer than 7 days, as there is a risk of addiction. Suppositories are introduced after complete bowel movement.
Unlike the original, the analogue consists of components of plant origin.
Sea buckthorn candles
Sea buckthorn candles are classified as reparants and regenerants. The main substance in rectal suppositories is sea buckthorn oil. It accelerates the healing of microcracks and restores the affected mucous membrane. It has anti-inflammatory, membrane-stabilizing and antioxidant properties.
The need to use this drug is determined by a qualified specialist. The list of indications for use includes:
- Cracks and ulcers of the colon.
- Proctitis.
- Haemorrhoids.
- Sphincteritis.
- Painful sensations during bowel movements.
- Atrophic, radiation and catarrhal lesions.
Suppositories are not used in the treatment of patients with hypersensitivity to sea buckthorn oil. Since suppositories are inserted into the anus, the presence of diarrhea may prevent the drug from being absorbed by the intestinal walls, so it is not advisable to carry out the procedure in this condition.
Among the negative effects, the most common are skin rashes, disturbances in the gastrointestinal tract, and itching in the anus.
The dosage is determined by the attending physician after a full examination and review of the test results. The standard instructions recommend administering one suppository per day for 10-14 days. If necessary, the course of treatment can be repeated.
Relief and substitute consist of different components. They have approximately the same degree of effectiveness.
Methyluracil
Methyluracil is a tissue stimulant that helps normalize trophism and tissue regeneration, intended for local use. The mechanism of action is determined by methyluracil. This substance is an immunostimulant, under the influence of which the process of cell regeneration is accelerated, the exchange of nucleic acids is normalized, and the body’s resistance to oxygen starvation and blood loss increases.
The need to use the drug arises when:
- Erosive and ulcerative colitis.
- Colpitis.
- Proctosigmoiditis.
- Sigmoiditis.
- Anal microcracks.
- Nonspecific vulvitis.
- Recovery in the postoperative period.
Features of Methyluracil
It is prohibited to use the drug in patients with hypersensitivity to its components, excessive development of granulation tissue, chronic or acute leukemia, malignant tumors in the bone marrow, hemoblastosis.
The medication rarely causes side effects. In some cases, itching and allergic reactions may occur.
In proctology, medicine is prescribed for exacerbation of pathologies. According to the instructions, the suppositories are inserted directly into the rectum, previously cleared of feces. 3-4 administrations of one suppository are allowed per day. The maximum permissible daily dose is 8 suppositories.
In pediatrics, children over 3 years of age may be prescribed 0.5 suppositories per 24 hours.
Methyluracil consists of other components and is effective in the acute form of the disease.
See also:
Instructions for use of the drug Gepazolon and its analogues
Relief or Proctosan - which is better?
Manufacturer: STADA, Germany
Release form: ointment and rectal suppositories
Active ingredient: Bufexamac + Bismuth subgallate + Lidocaine hydrochloride
The analogue in the form of Proctosan suppositories and ointments is closer in composition to Relief Ultra; they have an astringent, wound-healing, drying, local anti-inflammatory and anesthetic effect.
This analogue is used for hemorrhoids, fissures, ulcers of the anus and rectum to relieve inflammation and itching.
Relief or Posterisan – which is better?
Manufacturer: Dr.
Kade, Germany Release form: ointment and rectal suppositories
Active ingredient: Microbial cells of Escherichia coli killed by phenol
Posterizan can replace Relief suppositories as an anti-inflammatory and antipruritic, but you can also combine these two drugs, thanks to the special composition of the analogue - inactivated bacteria and their metabolic products.
The drug improves immunity, normalizes capillary permeability and regenerates damage.