Theraflex is a combination medication that is produced in capsules with the active ingredients - glucosamine hydrochloride and sodium chondroitin. The drug is in a high price segment, so many patients prefer to take a medication course with analogues that cost less than Teraflex.
Teraflex is prescribed as part of the combined treatment of pathologies of the musculoskeletal system that occur due to dystrophic or degenerative changes in joints and connective tissue. The drug is used in the treatment of the following pathologies:
- osteoarthritis and osteochondrosis of different parts of the spine;
- changes in the spine and joints of degenerative origin;
- injury to the bone apparatus (the medication accelerates the process of bone healing and callus growth).
Do not use Teraflex for:
- kidney dysfunction and organ failure;
- allergies to the composition of the combined product;
- the age of the child is under 15 years;
- pregnancy and pregnancy.
Teraflex is prescribed with restrictions for:
- diabetes mellitus;
- bronchial type asthma;
- the body's predisposition to bleeding.
Teraflex should be taken in the first 21 days of therapy three times a day, without attachment to food, 1 capsule. From the 22-23rd day of treatment, the dosage is reduced to 2 capsules per day, divided into 2 administration procedures. The average therapeutic course lasts 90-180 days or longer.
Side effects:
- abdominal pain, constipation;
- flatulence, diarrhea and vomiting;
- headache and dizziness;
- sleep rhythm disturbance;
- peripheral edema;
- skin allergy reactions - skin rash and itching.
pharmachologic effect
Stimulates cartilage restoration and reduces inflammation.
- Chondroitin sulfate is a substance involved in the formation of healthy cartilage tissue. At the same time, the viscosity of the synovial fluid is maintained, and enzymes that destroy cartilage are inhibited. In osteoarthritis, it reduces the manifestations of the disease and helps reduce the dose of non-steroidal anti-inflammatory drugs.
- Glucosamine sulfate improves the synthesis of substances that are the main components of cartilage, joint membranes and synovial fluid.
- Ibuprofen provides an anti-inflammatory effect, reduces pain, and has an antipyretic effect due to the blockade of cyclooxygenase-1 and cyclooxygenase-2 .
Glucosamine and chondroitin increase the analgesic effect of ibuprofen .
Reviews on the choice of Teraflex analogues
Reviews about Teraflex and analogues are positive and their high effectiveness is noted by both specialists and patients:
- Butenko S.N., orthopedist: “Very often patients come to us with severe arthrosis, especially coxoarthrosis and osteoarthrosis. For treatment as part of complex therapy, I always prescribe Theraflex, which helps to quickly block the progress of organ destruction and helps tissue regeneration. Among the analogues, I would like to mention Chondroguard, Artru, Artiflex and Chondroitin. These drugs are cheaper than Teraflex, but show the same effectiveness.”
- Yuri, 57 years old: “I have been taking Teraflex for coxoarthrosis for 3 years in courses of 3-6 months. The destruction of the joint has been stopped. Teraflex has minimal toxicity and I do not experience any side effects. The price may be higher."
Teraflex is one of the best medications for the treatment of joints of degenerative and dystrophic origin. The disadvantage of the drug is its high cost. Only a doctor can select the necessary cheaper analogue, which is no less effective than Teraflex.
Pharmacodynamics and pharmacokinetics
The bioavailability of glucosamine is about 25%, with the highest concentration of the substance found in joint cartilage, liver and kidneys, the highest concentration found in liver, kidneys and joint cartilage. Almost 30% of the incoming substance remains in the muscles and bones for quite a long time. The half-life is about 3 days, excreted in the urine.
The bioavailability of chondroitin sulfate after absorption from the gastrointestinal tract is approximately 13%. The maximum concentration occurs after 4 hours in the blood, and in the intra-articular fluid - within 5 hours. A large amount is found in synovial fluid. It is excreted from the body in urine.
After oral administration of ibuprofen, its maximum concentration occurs within 1 hour. Capable of binding to plasma proteins by 99% and penetrating into the intra-articular fluid. Metabolized in the liver, excreted by the kidneys. The half-life is about 3 hours.
Popular Russian-made substitutes
Russian Teraflex substitutes are much cheaper than the original product, but relieve pain in joints, bones and muscles with the same effectiveness as Teraflex.
Menovazin
The Russian medication Menovazin based on menthol, procaine and benzocaine is an antipruritic medication with a selective and cooling effect. The use of the drug causes reflex changes in skin receptors, affects the surface of the epidermis and deep inside the arterial membranes, producing an anesthetic effect.
Menovazine is prescribed for:
- neuralgia of various etiologies;
- myalgia and arthralgia;
- dermatoses, which are accompanied by severe itching.
Menovazin is not used in therapy in these situations:
- allergy to a medication;
- impaired skin integrity;
- patients under 12 years of age.
Menovazin should be prescribed with caution to women who are breastfeeding and during pregnancy.
Menovazin is applied locally to the site of the pathology 2-3 times a day and rubbed with light massage movements. This drug is intended for topical use, applied to the surface of the skin with the exception of places where the integrity of the skin is compromised. To achieve an analgesic effect, it should be applied 2-3 times a day. The drug can be used in monotherapy, as well as in combination treatment. Menovazine rarely shows side symptoms, but sometimes patients complained of the following signs of negative effects:
- skin allergies in the form of hives, redness and rash;
- irritation and swelling at the site of application of the medicine.
Chondroxide
Most often, Chondroxide is used in the treatment of osteochondrosis of the spine, as well as joints of peripheral organs. You need to apply the gel or ointment 2-3 times a day for 14-90 days. The duration of the treatment course is prescribed by the doctor.
Tablets are used in the treatment of degenerative pathologies of the spine, as well as small and large joints.
Prescribed with great caution during pregnancy and lactation. It is recommended to suspend lactation at the time of therapy.
The tablets are intended to be taken orally, without being tied to meals. Dosage – 500 mg (1 tablet) twice a day. Duration of taking tablets is up to 6 months.
If Chondroxide is taken in therapeutic dosages, then there are no negative effects at all.
Elbona
Elbona is a chondroprotector with anti-inflammatory properties and analgesic effect based on glucosamine sodium chloride sulfate. Elbona is prescribed for joints with the following diseases:
- osteoarthritis and spondyloarthrosis;
- osteoarthritis and coxoarthrosis.
It is prohibited to prescribe for:
- personal drug intolerance;
- cardiac pathologies and phenylketonuria;
- history of seizures;
- severe pathologies of the kidneys and liver;
- GW and pregnancy.
Elbona therapy can be carried out with restrictions in the following cases:
- hypotension and myocardial failure;
- asthma of bronchial etiology;
- diabetes mellitus
The solution is administered intramuscularly (intravenous administration is prohibited). To prepare the solution, mix 2 components A + B. 3 times a week you need to administer 3 ml. Therapy can last 1-1.5 months.
Among the adverse reactions to Elbona are:
- nausea, diarrhea, bloating and vomiting;
- headache, tongue numbness and dizziness;
- disorientation and hallucinations;
- tremor of the limbs;
- arrhythmia;
- anaphylactic shock.
Contraindications
- ulcerative lesions of the gastrointestinal tract ( gastric ulcer , Crohn's disease , ulcerative colitis);
- gastrointestinal bleeding;
- intracranial hemorrhages;
- bleeding disorders;
- aspirin asthma;
- hemorrhagic diathesis;
- children under 12 years of age;
- individual intolerance to the constituent components of the drug;
- pregnancy and breastfeeding;
- hypersensitivity to aspirin and NSAIDs.
Prescribed cautiously for arterial hypertension, heart failure, severe damage to kidney and liver function, gastrointestinal diseases, hyperbilirubinemia, nephrotic syndrome, blood diseases, diabetes mellitus , bronchial asthma , and in elderly patients.
In case of intolerance to seafood products, the likelihood of developing an allergy to the drug increases.
Popular substitutes in ointment/cream form
Among the Teraflex analogues there are also medications that are produced in the dosage form of an ointment/cream for application to the skin in the affected area. The therapeutic effect of these analogues is similar to Teraflex.
Artiflex
The drug contains the following active ingredients: glucosamine hydrochloride, ibuprofen and allantoin. Artiflex has the following properties on the body:
- analgesic and antioxidant;
- chondroprotective and membrane stabilizing;
- antiphlogistic and antiexudative.
Artiflex cream is prescribed for the treatment of the following diseases:
- arthropathy and osteochondrosis of the back;
- osteoarthritis and diseases of the articular system, which are accompanied by swelling.
For kidney pathologies, the drug is prescribed with great caution and under the supervision of a doctor. Do not use Artiflex in the following situations:
- allergy to the composition of the cream;
- dermatoses and weeping eczema;
- asthma;
- up to 12 years;
- trophic open wounds;
- lactation and pregnancy.
The cream is applied twice or thrice a day locally to the areas of the disease. It is necessary to rub the cream into the skin for 2-3 minutes. Therapy can last 2-3 weeks.
The body's reactions to the use of cream in therapy:
- the digestive organs react with the following symptoms - severe nausea ending with vomiting, constipation, flatulence and diarrhea, epigastric and abdominal pain;
- skin allergies - hives, redness and itching at the site of application of the medicine;
- Signs of a negative effect of the drug in the genitourinary organs may appear - urinary retention.
Vipratox
Vipratox is a medication for topical use and has an analgesic and anti-inflammatory effect on the human bone, joint and muscle systems. The medicine nourishes tissues affected by trophic disease. Included:
- viper venom extract;
- synthetic analogue of camphor;
- fir emulsion;
- salicylic acid;
- sodium chloride.
The ointment is used to treat pathologies of bone and muscle tissue, which are accompanied by severe pain:
- rheumatism and sciatica;
- neuralgia and myalgia;
- lumbago and arthralgia;
- radiculitis and osteochondrosis.
Do not use ointment for the following reasons:
- hypersensitivity;
- pregnancy (1st and 3rd trimester);
- age up to 12 years;
- lactation.
Vipraktox is used only for application to the skin - apply 5-10 ml of cream to the site of inflammation and slowly rub in. The procedure should be carried out 2-3 times a day. It is important to avoid getting the cream on mucous membranes and open wounds. For children over 12 years of age, the dosage should be halved and not used more than 2 times a day, in order to avoid the development of allergies. The duration of application is determined personally by the doctor, based on the pathology and the degree of its progression.
Side symptoms are observed infrequently, only 2-3% of patients report skin irritation and itching at the sites of application. Also, at the site where the cream gets on the epidermis, a rash and redness may appear.
Chondroitin ointment
Chondroitin ointment is a medication based on chondroitin sulfate that relieves inflammation and also has a chondroprotective effect. The ointment is prescribed for patients with joint and muscle pain, as well as for degenerative damage to the bones of the spine - osteoporosis, arthrosis and osteochondrosis of the spine.
Do not prescribe ointment if the patient:
- hypersensitivity to the constituent agents;
- age under 12 years;
- acute form of inflammation at the site of application.
The ointment is prescribed with caution to women during pregnancy, patients with thrombophlebitis and a predisposition to subcutaneous bleeding.
The area where the ointment is applied must be thoroughly rinsed with warm water and dried. Apply the ointment in a thin layer (on average 1-3 cm) and slowly rub into the area of inflammation. Carry out the procedure for applying the ointment every 8 hours, and after removing severe symptoms - after 12 hours. The average duration of a medication course is up to 3 weeks.
Chondroitin ointment, when used in therapeutic dosages, does not cause side symptoms, only sometimes the patient may feel a burning sensation after application.
Diclofenac
Diclofenac is manufactured in various forms with the main ingredient diclofenac sodium. Diclofenac ointment or gel is used to treat the following pathologies:
- degenerative changes in bone and muscle tissue;
- inflammatory processes in the musculoskeletal system;
- painful symptoms of rheumatic and non-rheumatic etiology;
- joint pain and pain in muscle fibers;
- post-traumatic inflammatory processes and pain after a dislocation, sprain or bruise;
- arthritis and spondyloarthritis;
- bursitis and tendovaginitis;
- osteochondrosis and osteoarthrosis;
- sciatica and lumbago.
Diclofenac is not used if you are allergic to its composition, as well as in children under 6 years of age and if the integrity of the skin is compromised - wounds, burns.
You should take the ointment with caution in the 1st and 2nd trimesters of pregnancy (it is strictly prohibited in the 3rd trimester), during the lactation period and in case of kidney dysfunction.
For children twice a day, and for adults 3-4 procedures per day - apply a thin layer of ointment to the source of pain. A single dosage should be within 2 mg. The minimum course of therapy is 2 weeks, after which you need to consult a doctor.
Side effects:
- formation of eczema and papules on the body;
- dermatitis, peeling and vesicles;
- skin redness and swelling;
- rash, bronchospasms and urticaria.
Side effects
Nausea, diarrhea , abdominal pain, flatulence, constipation and allergic reactions may occur. If the drug is discontinued, the side effects disappear.
Most adverse reactions occur to ibuprofen , which is part of the drug.
- Digestive system: dry mouth, stomatitis, abdominal pain, heartburn, nausea and vomiting, flatulence, constipation and diarrhea, pancreatitis and hepatitis.
- Respiratory system: bronchospasm and shortness of breath.
- CNS: dizziness, headache, irritability, insomnia, drowsiness, depression, hallucinations and confusion.
- Sense organs: hearing changes (noise or ringing in the ears, hearing loss), dry eyes, double vision, swelling of the eyelids and conjunctiva.
- Heart and blood vessels: rapid heartbeat, increased blood pressure, heart failure.
- Urinary system: nephrotic syndrome , cystitis , nephritis , acute renal failure.
- Hematopoietic system: thrombocytopenia , anemia , leukopenia , thrombocytopenic purpura, increased duration of bleeding.
- Allergic reactions: erythematous rash , skin itching, urticaria, anaphylactic shock , Quincke's edema , bronchospasm, exudative erythema multiforme, Lyell's syndrome, allergic rhinitis, eosinophilia.
The cheapest similar products for joints
Pharmaceutical companies in Russia, Ukraine and Belarus present on the market cheap analogs of Theraflex for joints that are not inferior to it in effectiveness.
Protecon
Protekon is a non-steroidal drug with inflammatory properties and antirheumatic effects. Developed on the basis of glucosamine sulfate and chondroitin sulfate. Prescribed for the following diseases:
- osteochondrosis and osteoarthrosis;
- arthrosis of intervertebral discs;
- osteoporosis and periodontopathy;
- injuries and bone fractures;
- postoperative therapy.
The medicine is not used in treatment for the following reasons:
- allergy to medication;
- thrombophlebitis and bleeding susceptibility;
- kidney failure;
- diabetes;
- childhood;
- pregnancy.
During lactation, you can be treated with Protekon only after transferring the child to artificial feeding.
Tablets must be taken, regardless of the time of meal, according to the following scheme:
- at the initial stage of treatment for 3 weeks - 1 tablet three times a day;
- from 4 weeks – the dosage is reduced to 2 times a day, also 1 tablet.
Duration of therapy is 2-3 months. The frequency of courses per year is 2-3 courses.
Adverse reactions:
- skin allergies;
- disturbance in the digestive tract;
- disturbance of peripheral blood flow and functioning of the visual organ.
Chondroitin
The combined medicine Chondroitin is manufactured in the form of gelatin capsules for oral use based on chondroitin sulfate. Medications are prescribed for the following diseases:
- osteoarthritis;
- osteochondrosis;
- arthropathy and bone fractures;
- spondylosis.
The use of Chondrotin in therapy reduces the need for analgesic medications.
It is prohibited to prescribe the Teraflex analogue:
- children under 15 years of age;
- if you are allergic to components in the medicine;
- with kidney pathologies and phenylketonuria;
- patients prone to bleeding;
- during pregnancy and lactation.
You need to take capsules half an hour before meals, 1 capsule twice a day, orally, half an hour before meals. Usually take 1 capsule twice a day. In the fourth week of treatment, the dosage is reduced to 1 capsule once a day. Therapy lasts 2-6 months.
During the course of medication, it is prohibited to take alcohol and sugar. Negative effects occur rarely, but sometimes manifest themselves with the following symptoms:
- digestive disorders - gastralgia, nausea and vomiting, diarrhea or constipation;
- allergic manifestations on the skin - hives, itching and redness;
- swelling.
Interaction
Ethanol , tricyclic antidepressants , rifampicin , barbiturates when taken together increase the risk of liver damage.
Teraflex Advance is able to reduce the effect of antihypertensive drugs (ACE inhibitors and calcium channel blockers), furosemide , hydrochlorothiazide and uricosuric drugs.
The drug enhances the effects of antiplatelet agents , anticoagulants and fibrinolytics , thereby increasing the risk of bleeding.
Potentiates the side effects of drugs that have an ulcerogenic effect - NSAIDs, ethanol, estrogens, corticosteroids.
Antacids reduce the absorption of ibuprofen .
Teraflex Advance increases the effect of insulin and other hypoglycemic drugs, increases the concentration of cardiac glycosides, methotrexate and lithium-containing drugs in the blood.
The analgesic effect of the drug may be increased by caffeine .
Ibuprofen reduces the anti-inflammatory and antiplatelet effect of aspirin.
Cefoperazone , cefamandole , valproic acid , plicamycin , cefotetan increase the risk of developing hypoprothrombinemia.
Combined use with myelotoxic drugs increases the toxic effect on the blood system.
Taking with gold preparations and cyclosporine increases nephrotoxicity and hepatotoxicity .
Glucosamine can reduce the effect of doxorubicin , hypoglycemic drugs, teniposide , chloramphenicol , semisynthetic penicillins and increase the absorption of tetracyclines.
Chondrogard
Chondroguard belongs to the pharmacological group of chondroprotectors. The drug has a regenerating, chondrostimulating effect. Available in the form of a solution for intramuscular administration. The active component of the drug is chondroitin sulfate. Chondroguard is prescribed in the presence of symptoms of degenerative-dystrophic diseases of the spine and joints, as well as during the recovery period after fractures. The drug helps accelerate the formation of callus. The dosage, frequency of administration and duration of treatment are selected individually. On average, therapy takes about 1 month. The cost of 1 package of Chondrogard is 700-1000 rubles. depending on the volume of ampoules and their quantity. For the full course you will need 3 packs. This allows us to consider the drug not the most budget-friendly among chondroprotectors.
Teraflex Advance price, where to buy
The price of Teraflex Advance is from 406 rubles. for 30 capsules up to 1464 rub. for 120 capsules. In Ukraine, the average cost of the drug is about 373 UAH. for 120 capsules.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Teraflex Advance capsules 120 pcs. Contract Pharmacal Corporation
RUB 2,811 order
Pharmacy Dialogue
- Teraflex Advance (caps. No. 60)Contract
790 rub. order
- Teraflex Advance capsules No. 120Contract
RUR 2,691 order
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Pharmacy24
- Teraflex Advance No. 60 capsules Contract Pharmacal Corporation, USA
253 UAH. order - Teraflex Advance No. 120 capsules Contract Pharmacal Corporation, USA
425 UAH. order
PaniPharmacy
- Teraflex Advance capsule Teraflex Advance capsules No. 120, Contract Pharmacal Corporation
464 UAH order
- Teraflex Advance capsule Teraflex Advance capsules No. 60, Contract Pharmacal Corporation
251 UAH order
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Prices for the drug and main analogues?
Teraflex analogues are in different price categories, and their cost directly depends on the country of manufacture. Foreign generics can cost even more than Teraflex, while Russian medications are several times cheaper.
Name of similar products | Release form | Quantity in 1 package (pieces, grams) | Price |
Teraflex | capsules | 60 120 | 1368-1861 2620-2700 |
Protecon | pills | 60 | 1283-1300 |
Chondroitin | gelatin capsules | 60 | 1279-1300 |
Artiflex | cream | 40 100 | 270-300 560-600 |
Vipraktox | cream | 40 | 250-270 |
Chondroitin ointment | 25 | 296-300 | |
Diclofenac | ointment | 50 | 387-420 |
Artra | pills | 30 | 1189-1280 |
Artron | complex | 60 | 1558-1630 |
Rumalaya | pills | 60 | 110-180 |
Arthrofoon | pills | 100 | 324-400 |
Osteoarthisi Active Plus | pills | 30 | 790-800 |
Revalgin | capsules | 20 | 110-137 |
Nimesil | capsules | 20 | 675-700 |
Chondrolone | solution | 10 | 944-1000 |
Sustagard | solution | 10 | 769-800 |
Arthrox | solution | 10 | 1080-1100 |
Menovazin | solution | 40 ml | 19-78 |
Chondroxide | ointment | 30 g | 318-400 |
Elbona | solution | 6 | 1254-1280 |
Don
Dona is a chondroprotector used for the treatment of degenerative diseases of the musculoskeletal system. The active substance of the drug is glucosamine. Available in the form of powder, tablets and solution for injection. Dona activates the restoration of cartilage and bone tissue, stimulates the natural production of hyaluronic acid, increases joint mobility, and reduces the severity of pain. The course of taking the drug is 1.5-2 months. The disadvantage of the drug can be considered its cost. The price is 1200-1400 rubles depending on the region of residence.
Mucosat
Mucosat is a chondroprotector used to treat diseases of the musculoskeletal system. Available in the form of an injection solution. The active ingredient of the drug is chondroitin sulfate. Mucosat normalizes metabolic processes in hyaline tissue and activates regeneration in articular cartilage. The drug has an analgesic and anti-inflammatory effect. Prescribed for therapeutic and prophylactic purposes. At the beginning of treatment, 1 ml per day is administered. If well tolerated, the dosage is increased to 2 ml. The course of treatment consists of 30 injections. Despite the wide range of indications and positive effects, there are reviews about the lack of effectiveness of Mucosat.
If there are indications for prescribing medications, it is recommended to consult a doctor. Only a specialist will be able to determine the severity of the disease and select the appropriate treatment.
Ukrainian analogues
When choosing substitutes, you can pay attention to Ukrainian products. Among them, there are available options that can be used by the patient.
Let's consider the most popular of them, which a specialist can prescribe.
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- Protekon . Its cost on average is from 400 rubles. It contains glucosamine, which restores pathologies of the musculoskeletal system. It should not be used by people with thrombophlebitis, as well as during lactation and pregnancy.
- Artiflex . This is a profitable substitute for the reason that its price starts from 140 rubles. Helps start the regeneration of destroyed cartilage tissue. Contraindicated for kidney problems, diabetes and pregnancy.
These products are quite cheap, but you need to consult a doctor about their effectiveness. If a person wants to get the most effective drugs, then it is better for him to pay attention to foreign drugs.
- The drug is prescribed to patients with osteoarthritis of the spine and peripheral joints of varying severity;
- Cheaper analogues of Movalis: review and comparison of more affordable drugs;
- - cheap analogues of Xarelto.