TOP 12 analogues of the drug Triderm: list of inexpensive ointments and creams

Compound

Top 5. Betaderm

Rating (2021): 4.51

• Characteristics

  Average price: 205 rub. (15 g)

• Manufacturer: Jelfa (Poland)
• Active ingredient: Betamethasone + Gentamicin
• Dispensed from pharmacies: without a prescription

Betaderm is a partial analogue of Triderm based on two active ingredients betamethasone and gentamicin. The Polish-made product is affordable, sold without a prescription, and helps with many skin diseases, but only if there is no fungal infection. Recommendations for use are standard - twice a day. The ointment is not recommended for children under 2 years of age. There are still relatively few reviews about Betaderm; it is prescribed much less frequently than the more popular Triderm or its full analogue, Russian-made Akriderm GK.

Advantages and disadvantages

• Affordable price
• Partial analogue of Triderm
• Sold without a prescription

• Contains no antifungal component

Pharmacodynamics

Combined preparation for external use.

Triderm® ointment and cream combine the anti-inflammatory, antipruritic, antiallergic and antiexudative effect of the GCS betamethasone dipropionate with the antifungal activity of clotrimazole and the broad antibacterial effect of gentamicin sulfate.

Clotrimazole has an antifungal effect by disrupting the synthesis of ergosterol, which is an integral part of the cell membrane of fungi. Active against Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, Candida albicans, Malassezia furfur (Pityrosporum orbiculare).

Gentamicin sulfate, a broad-spectrum antibiotic from the aminoglycoside group, is bactericidal and provides highly effective local treatment of primary and secondary bacterial skin infections. Active against gram-negative microorganisms: Pseudomonas aeruginosa, Enterobacter aerogenes, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae; gram-positive microorganisms: Staphylococcus aureus (coagulase-positive, coagulase-negative and some strains producing penicillinase).

Top 3. Celestoderm-B with garamycin

Rating (2021): 4.58

The highest dosage of betamethasone, Celestoderm-B with garamicin, contains slightly more than two times more betamethasone, which is why it is sold in pharmacies only by prescription.

• Characteristics

  Average price: 432 rub. (15 g)

• Manufacturer: Schering-Plough (Belgium)
• Active ingredient: Betamethasone + Gentamicin
• Dispensed from pharmacies: by prescription

Celestoderm-B with garamicin is a drug with a combined composition, which is a partial analogue of Triderm. It contains two active ingredients - betamethasone and gentamicin, but does not contain the antifungal component clotrimazole. In many cases, an antibiotic and a glucocorticosteroid, which is more than 2 times more abundant here, are quite sufficient to treat many skin diseases. The list of indications for use is similar, but does not contain diseases of fungal origin. Ointments are produced by one brand, but Celestoderm-B with garamycin is cheaper. It is worth considering that this drug is sold in pharmacies only with a prescription, although it is not required to purchase most of the other products presented in the rating.

Advantages and disadvantages

• More affordable price
• Suitable for children from 6 months
• Contains 2 times more hormonal component

• Sold by prescription
• Contains no clotrimazole

Indications for Triderm®

Dermatoses complicated by infections caused by pathogens sensitive to the drug, or when such infections are suspected, including:

simple and allergic dermatitis;

atopic dermatitis (including diffuse neurodermatitis);

limited neurodermatitis;

eczema;

dermatomycosis (dermatophytosis, candidiasis, lichen versicolor), especially when localized in the groin area and large folds of the skin;

simple chronic lichen (limited neurodermatitis).

Top 5. Candide-B

Rating (2021): 4.43

• Characteristics

  Average price: 550 rub. (15g)

• Manufacturer: Glenmark Pharmaceuticals Ltd. (India)
• Active ingredient: Beclomethasone + Clotrimazole
• Dispensed from pharmacies: without a prescription

Candide-B is a cream based on the antifungal component clotrimazole and the hormonal beclomethasone. To be completely similar in action to Triderm, the only thing missing in the composition is an antibiotic. Candide-B is prescribed for dermatoses of predominantly fungal origin, which is why its list of indications is relatively small. But in its field, the remedy works perfectly, relieving conditions within a couple of days and helping to achieve a complete cure in 5-7 days. The price range of the drug is average, at the level of many analogues. The cream receives mostly good reviews. Most people who try it do not encounter side effects and other unpleasant consequences when taking it.

Advantages and disadvantages

• Combined composition
• Highly effective in the treatment of dermatoses of fungal origin
• Improvements on the second day

• Average, but not the most affordable price range

Side effects

Very rarely, when using the drug Triderm®, the following are observed: burning sensation, erythema, exudation, pigmentation disorders and itching.

Caused by local corticosteroids (especially when using occlusive dressings): burning sensation, itching, dry skin, folliculitis, hypertrichosis, acne, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin maceration, development of secondary infection, skin atrophy, stretch marks, prickly heat.

Caused by clotrimazole: erythema, tingling sensation, blistering, peeling, local swelling, itching, urticaria, skin irritation.

Caused by gentamicin: transient skin irritation (erythema, itching), usually not requiring discontinuation of treatment.

Top 4. Pimafukort

Rating (2021): 4.48

The most discussed We found 361 reviews about Pimafukort, which allows us to call it the most discussed among all the drugs participating in the rating.

A complete analogue of Triderm in action, Pimafukort is completely different in the composition of the active components from Triderm, but has the same effect, since it contains an antibiotic, a hormone and an antifungal agent.

• Characteristics

  Average price: 640 rub. (15 g)

• Manufacturer: Temmler (Italy)
• Active ingredient: Natamycin + Neomycin + Hydrocorzizone
• Dispensed from pharmacies: without a prescription

Pimafucort is available in both ointment and cream formats. The drug is in many ways similar to Triderm, as it also contains an antibiotic, hormone and antifungal component. The indications for use of the products are almost identical, but Pimafucort has fewer contraindications. Another advantage is that it is allowed for children from one year old, since the hormonal component included in its composition is less dangerous. You can buy the product in pharmacies without a prescription, but its cost can hardly be called affordable. There are a lot of reviews about the medicine, and it receives high ratings. Many doctors speak positively about the medicine and prescribe it to children even in the first year of life.

Advantages and disadvantages

• Three components included
• The action is as similar as possible to Triderm
• High marks from doctors and ordinary people

• Cost is above average

Overdose

Symptoms: with long-term use of local corticosteroids in high doses, suppression of adrenal function with the development of secondary adrenal insufficiency and symptoms of hypercortisolism, including Cushing's syndrome, is possible. An overdose of clotrimazole when applied topically does not lead to the appearance of any symptoms. With a single overdose of gentamicin, the appearance of any symptoms is also not expected. Long-term treatment with gentamicin in high doses can lead to the growth of insensitive flora.

Treatment: symptomatic. Acute symptoms of hypercortisolism are usually reversible. If necessary, electrolyte imbalance is corrected. In case of chronic GCS toxicity, gradual withdrawal of GCS is recommended.

Top 1. Akriderm GK

Rating (2021): 4.74

The most popular complete analogue of Triderm Akriderm GK is a complete analogue of Triderm ointment in composition and the most popular in terms of the number of prescriptions and the number of reviews - there are already 275 of them.

• Characteristics

  Average price: 460 rub. (15 g)

• Manufacturer: AKRIKHIN (Russia)
• Active ingredient: Betamethasone + Gentamicin + Clotrimazole
• Dispensed from pharmacies: without a prescription

Akriderm GK is a complete analogue of Triderm. Russian-made cream contains the same combination of active ingredients, but costs a third less, which is why it is in high demand. If you buy Akriderm GK in a package of not 15, but 30 grams, the benefits will be even greater. Providing simultaneously anti-inflammatory, antifungal and antibacterial effects, the drug helps to quickly solve the problem of dermatitis of various origins. Side effects are possible, but rare; the drug is indicated for children from 2 years of age. The ointment receives good reviews, although many still consider its cost high. There are also complaints about the quality of the tube. Positive changes are noticeable after just a few uses.

Advantages and disadvantages

• Analog of Triderm made in Russia
• There are packages of 15 and 30 grams
• Available in cream and ointment format
• The cost is a third cheaper

• The tube sometimes leaks

See also:

• 20 best creams and ointments for allergies

to the beginning of the rating

special instructions

Cannot be used in ophthalmic practice.

Prolonged topical use of antibiotics can sometimes lead to the growth of resistant microflora. In this case, as well as if irritation, sensitization or superinfection develops while using the drug Triderm®, treatment should be interrupted and appropriate therapy should be prescribed. Cross-allergic reactions with aminoglycoside antibiotics have been observed.

Any side effects that occur with the use of systemic corticosteroids, including suppression of the function of the adrenal cortex, can also be observed with local use of corticosteroids, especially in children.

Systemic absorption of GCS or gentamicin when applied topically will be higher if treatment is carried out over large surfaces of the body or when using occlusive dressings. Avoid applying gentamicin to open wounds or broken skin. Appropriate precautions should be taken in such cases, especially when treating children.

It is recommended to discontinue the drug after long-term use gradually.

Use in pediatrics

Children from 2 years of age are prescribed only according to strict indications and under medical supervision, because Systemic side effects associated with betamethasone may develop. When using the drug Triderm®, like many other topical corticosteroids on large surfaces and/or with an occlusive dressing, the function of the hypothalamic-pituitary-adrenal system may be suppressed, a decrease in the excretion of growth hormone, as well as an increase in ICP may be observed.

Impact on the ability to drive vehicles and operate machinery. No effect of Triderm® on the ability to drive vehicles or operate machinery has been identified.

Top 2. Candiderm

Rating (2021): 4.62

Minimal differences from Triderm Candiderm ointment differs from Triderm in one component. Beclomethasone, which is included in the composition, is also a glucocorticosteroid, so the differences between these drugs are minimal.

• Characteristics

  Average price: 540 rub. (15 g)

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• Manufacturer: Glenmark (India)
• Active ingredient: Beclomethasone + Gentamicin + Clotrimazole
• Dispensed from pharmacies: without a prescription

Candiderm can safely be classified as an analogue of Triderm, because the products have an almost identical composition. The difference between them is only in one component - Triderm contains the glucocorticosteroid betamethasone, and Candiderm also includes beclomethasone, which belongs to this category. Another difference is the lower dosage of the hormonal component, which makes the product, on the one hand, safer, and on the other, slightly less effective. Indications for use are identical, as are recommendations for use twice a day. The drug is approved for children only from 7 years of age. There are relatively few reviews about Candiderm ointment, but the medicine receives very high ratings in them. The cost of the product is only slightly cheaper than Triderm, but this difference is significant for many buyers.

Advantages and disadvantages

• Almost complete analogue of Triderm
• High efficiency
• No negative reviews

• Children are only allowed from 7 years old
• High price

See also:

• 10 best remedies for itchy skin

Clotrimazole or Triderm

Clotrimazole is a domestic antifungal drug, also produced by foreign manufacturers. It is part of Triderm and complements the properties of other components (hormone and antibiotic).

For fungal skin infections, therapy with Clotrimazole alone is possible. In case of mixed nature of dermatoses, monotherapy is ineffective, Triderm is better.

Cost of medicines

Prices for analogues of the drug Triderm depend on the generic manufacturer and on the country in which the analogues were produced. The cost of imported substitutes is in the same price segment as Triderm, and Russian analogues are much cheaper in price than the original drug.

Top 3. Hyoxysone

Rating (2021): 4.68

Best price Gioxyzon is the most affordable drug among Triderm analogues participating in the rating and the winner in the “Best Price” nomination.

• Characteristics

  Average price: 80 rub. (10 g)

• Manufacturer: Nizhpharm (Russia)
• Active ingredient: Hydrocortisone + Oxytetracycline
• Dispensed from pharmacies: by prescription

Gioksizon is an inexpensive but high-quality ointment made in Russia, which is somewhat similar in action to Triderm. It contains two components - the antibiotic oxytetracycline and the glucocorticosteroid hydrocortisone. The list of indications is largely similar to Triderm, but it does not include dermatoses of fungal origin. Judging by the number of positive reviews, Gioksizon is quite popular, including due to its affordable cost. Good opinions about him come from both doctors and ordinary people. The product is sold only by prescription and this is perhaps its only drawback. Another disadvantage is the ban on use in children under 12 years of age.

Advantages and disadvantages

• Low cost
• Two components included
• Lots of positive reviews

• Sold by prescription
• Prohibited for children under 12 years of age