What is Dimexide used for?
The drug is prescribed for problems with the functioning of the musculoskeletal system. In addition, in case of subcutaneous damage to soft tissues, Dimexide actively relieves the inflammatory process. The ability of the drug to enhance the effect of other drugs is often used by doctors in antibacterial therapy. Direct indications for prescribing Dimexide are:
- bursitis;
- arthrosis;
- arthritis;
- radiculitis;
- gout;
- osteochondrosis;
- pain syndrome due to intervertebral hernia;
- scleroderma;
- skin ulcers;
- swelling accompanied by pain;
- synovitis
In addition to the above problems, Dimexide is also used in other areas, including cosmetology.
Dimexide 99% 100ml concentrate for preparing a solution for external use
pharmachologic effect
Anti-inflammatory agent for topical use.
Composition and release form Dimexide 99% 100ml concentrate for preparing a solution for external use
Concentrate:
- Active ingredient: dimethyl sulfoxide (dimexide) - 50 ml or 100 ml.
50 ml and 100 ml in orange glass bottles. The bottle along with instructions for use is placed in a cardboard pack.
Description of the dosage form
Colorless transparent liquid or colorless crystals, odorless or with a weak characteristic odor. Hygroscopic.
Directions for use and doses
Externally.
Dimethyl sulfoxide is produced in the form of a concentrate, from which, before use, an aqueous solution of the required concentration is prepared for application or irrigation (rinsing).
Moisten gauze pads in an aqueous solution of the required concentration and apply to the affected areas for 20-30 minutes. A plastic film and cotton or linen cloth are placed on top of the napkin. The recommended period for using applications is 10-15 days.
For the treatment of erysipelas and trophic ulcers - in the form of a 30-50% aqueous solution 2-3 times a day.
For eczema and streptoderma - compresses with a 40-90% aqueous solution.
For local anesthesia for pain syndromes - 25-50% aqueous solution in the form of compresses 2-3 times a day.
For facial skin and other highly sensitive areas, 10-20-30% aqueous solutions are used.
For children 12-18 years old, 20-30% aqueous solutions of dimethyl sulfoxide are used.
In skin plastic surgery, dressings with a 10-20% aqueous solution are used on transplanted skin auto- and homografts immediately after operations and in the subsequent days of the postoperative period until stable engraftment of the graft. A 5% solution of dimethyl sulfoxide in Ringer's solution is used as a preservative medium for storing skin homografts.
Purulent-necrotic and inflammatory foci and cavities are washed with less concentrated solutions (1-4%).
Preparation of an aqueous solution of dimethyl sulfoxide:
- Dimethyl sulfoxide content 10% - Number of parts of dimethyl sulfoxide / Number of parts of water 1/9;
- Dimethyl sulfoxide content 20% - Number of parts of dimethyl sulfoxide / Number of parts of water 1/4;
- Dimethyl sulfoxide content 25% - Number of parts of dimethyl sulfoxide / Number of parts of water 1/3;
- Dimethyl sulfoxide content 30% - Number of parts of dimethyl sulfoxide / Number of parts of water 3/7;
- Dimethyl sulfoxide content 40% - Number of parts of dimethyl sulfoxide / Number of parts of water 2/3;
- Dimethyl sulfoxide content 50% - Number of parts of dimethyl sulfoxide / Number of parts of water 1/1;
- Dimethyl sulfoxide content 90% - Number of parts of dimethyl sulfoxide / Number of parts of water 9/1.
Pharmacodynamics
Anti-inflammatory drug for external use, inactivates hydroxyl radicals, improves the course of metabolic processes in the site of inflammation. It also has local anesthetic, analgesic and antimicrobial effects; has moderate fibrinolytic activity.
Penetrates through the skin, mucous membranes, the membrane of microbial cells (increases their sensitivity to antibiotics) and other biological membranes, increases their permeability to drugs.
Pharmacokinetics
When dimethyl sulfoxide solution is applied to the skin, it is detected in the blood after 5 minutes. reaching maximum concentration after 4-6 hours, maintaining an almost unchanged level for 1.5-3 days. Dimethyl sulfoxide is excreted in urine and feces, both unchanged and in the form of dimethyl sulfone.
Indications for use Dimexide 99% 100ml concentrate for preparing a solution for external use
As part of complex therapy: diseases of the musculoskeletal system - rheumatoid arthritis, ankylosing spondylitis (Bekhterov's disease), deforming osteoarthritis (in the presence of damage to periarticular tissues), reactive synovitis, limited scleroderma, erythema nodosum, discoid lupus erythematosus, mycoses of the feet, keloid scars, thrombophlebitis, alopecia, eczema, streptoderma. erysipelas, bruises, sprains, traumatic infiltrates, purulent wounds, burns, radiculitis, trophic ulcers, acne, furunculosis. In skin plastic surgery - for preserving skin homografts.
Contraindications
Hypersensitivity to dimethyl sulfoxide, severe liver and/or renal failure, angina pectoris, severe atherosclerosis, glaucoma, cataracts, stroke, coma, myocardial infarction, pregnancy, breastfeeding, children under 12 years of age.
Application of Dimexide 99% 100ml concentrate for the preparation of a solution for external use during pregnancy and lactation
The use of the drug during pregnancy and breastfeeding is contraindicated.
special instructions
Some patients smell garlic in the air they breathe.
Before using the drug, it is necessary to test for tolerance to it. To do this, an aqueous solution of dimethyl sulfoxide of the required concentration is applied to the skin using a cotton swab soaked in it; the appearance of hyperemia and severe itching indicates hypersensitivity.
When stored at a temperature of 18 °C and below, crystallization of dimethyl sulfoxide occurs, which does not affect the quality of the drug. To melt the crystals, carefully heat the bottle in a water bath (water temperature no higher than 60 °C).
Impact on the ability to drive vehicles and operate machinery
Use of the drug in accordance with the instructions does not affect the ability to drive vehicles or operate moving mechanisms.
Overdose
Increased dose-dependent side effects are possible. In these cases, you should stop using dimethyl sulfoxide and rinse the damaged area. In case of accidental poisoning through the gastrointestinal tract, it is necessary to quickly rinse the stomach, remembering that dimethyl sulfoxide is quickly absorbed.
Treatment: symptomatic.
Side effects Dimexide 99% 100ml concentrate for preparing a solution for external use
Allergic reactions, contact dermatitis, erythematous rashes, dry skin, mild burning, itchy dermatitis, rarely - bronchospasm.
If side effects not described in the instructions occur, you should stop taking the drug and inform your doctor.
Drug interactions
Increases absorption and enhances the effect of ethanol (alcohol inhibits the elimination of the drug), insulin (with long-term use of the drug, the content of glucose in the blood plasma is monitored) and other drugs. Compatible with heparin, antibacterial agents, non-steroidal anti-inflammatory drugs. Increases the sensitivity of microorganisms to aminoglycoside and beta-lactam antibiotics; chloramphenicol, rifampicin, griseofulvin. Sensitizes the body to drugs for general anesthesia.
How to dilute Dimexide for hair
As a result of the fact that Dimexide was seen as a kind of catalyst for some local drugs, which quickly penetrated the cellular barrier deep into the tissues, Dimexide began to be used as part of cosmetic masks.
In particular, by mixing a teaspoon of the substance concentrate with essential oils, lemon juice, aloe extract and honey, you get an effective hair mask. Its regular use relieves hair from brittleness, gives rich shine and restores natural growth. And if you mix a teaspoon of Dimexide with ground red pepper and apply it to the scalp, holding for 15 minutes, you can wake up dormant bulbs, resulting in thicker curls.
How to dilute Dimexide for boils
Inflammation of the skin glands, which develop into boils, is often accompanied by a local increase in temperature and tension on the skin surface. In order to relieve pain and reduce tissue tension due to growing inflammation, dilute Dimexide in warm water in the proportion of 1 ml of concentrate per 10 ml of clean water. Cotton pads are soaked in the resulting solution and applied to the boils. It is important not to rub, rub, or knead an unruptured boil. Safe use is considered to be simply applying a moistened swab to the inflamed area.
Popular questions about Dimexide
How to dilute Dimexide?
The dilution proportion of Dimexide is related to the sensitivity of the skin. To prepare a concentrated solution, 50% is diluted 1:1, part Dimexide, part water. If you need a less concentrated solution, take fewer parts of Dimexide and more water.
How long to keep a compress with Dimexide?
A compress with Dimexide is applied for 20-30 minutes 2-3 times a day.
Where can you buy Dimexide?
Dimexide can be purchased on the official website of Pharmacy 911. We sell high-quality drugs.
How to dilute Dimexide for heel spurs
The situation with inflammation of the heel, called a heel spur, can be resolved not only through surgery. In some situations, a conservative method using Dimexide may help. It is important to begin treatment at the first signs of inflammation in order to prevent the disease from entering an irreversible phase when the help of a surgeon is required. For spurs, use a concentration of Dimexide diluted in water in a one to one ratio. Taking 20 ml of the drug you need to add 20 ml of water.
For severe pain, novocaine 2% is added to the solution in a volume equal to the amount of Dimexide and water. A cloth is moistened in the resulting liquid and placed on the sore spot. The compress is covered with polyethylene and a wool sock is put on.
Methods of application
To obtain a solution, Dimexide is diluted with water. To do this, take the required number of parts of Dimexide and the number of parts of water, depending on what concentration is needed:
| Concentration | How many parts of Dimexide | How many parts of water |
| 10% | 1 | 9 |
| 20% | 1 | 4 |
| 25% | 1 | 3 |
| 30% | 3 | 7 |
| 40% | 2 | 3 |
| 50% | 1 | 1 |
| 90% | 9 | 1 |
Dimexide for sinusitis
Sinusitis is an inflammation of the maxillary sinuses, accompanied by an accumulation of mucus pressing on the nasal cartilage from the inside. The disease may be accompanied by redness of the skin over the sinuses, as well as an increase in temperature, which is localized in the area of the inflammatory process. Dimexide will help relieve swelling of the mucous membranes and reduce inflammation in the nasal passages. It is mixed with saline solution in a ratio of 1:3.
You can also add aloe juice or vasoconstrictor nasal drops, for example, naphthyzine or phenylephrine. After moistening cotton swabs in the resulting solution, they are inserted into each nasal passage and kept in this position for up to 20 minutes. This treatment can be repeated for up to 7 days in a row.
Adverse reactions
The use of Dimexide, like any other drug, can lead to unpleasant side reactions. Among them:
- redness of skin areas;
- burning in the area of application;
- allergic reactions, manifested by nasal congestion, drainage from the eyes, bronchospasm and rhinitis;
- skin pigmentation;
- nausea;
- muscle weakness;
- dizziness;
At the first signs of illness as a result of using Dimexide, you should definitely stop therapy and discuss what happened with your doctor.
Note!
The description of the drug Dimexide on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
