Duspatalin 200 mg 30 pcs. extended release capsules

The article was prepared by a specialist for informational purposes only. We urge you not to self-medicate. When the first symptoms appear, consult a doctor.

Duspatalin is a myotropic antispasmodic that helps eliminate spasm of intestinal smooth muscles. In this case, the natural contractions of the intestinal wall will not be disrupted. Therefore, the drug can be taken without fear that the process of moving feces through the intestines will stop. The medicine is aimed exclusively at eliminating painful sensations.

The therapeutic effect of Duspatalin allows it to be used to relieve intestinal colic, irritable bowel syndrome, biliary colic, and pain in the stomach, regardless of their etiology. The drug is prescribed for functional disorders of the digestive system.

general characteristics

Duspatalin is produced in Holland. You can purchase the drug in the form of tablets of 135 g and capsules of 200 mg. The capsule form contains a larger amount of the main active ingredient compared to tablets. Due to this, you can achieve a long-lasting effect from taking the drug. Therefore, on the packaging of capsules there is the word “retard”, which means “slow down” in English.

The capsules are covered with a dense gelatin-based shell; each capsule contains white granules. Markings on capsules: “245”, “S”, “7”. You can purchase packages containing 10, 20, 30, 50, 60 and 90 capsules.

The tablets are round in shape and white in color. They can be purchased in the same quantities as capsules, and also in packs of 15, 40, 100 and 120 pieces.

Regardless of the release form, the main active ingredient remains the same - mebeverine. However, the auxiliary components in capsules and tablets are different. Their comparative characteristics are presented in the table.

Duspatalin or Niaspam

Niaspam is a good analogue, the active ingredient of which is mebeverine. This is a high-quality myotropic antispasmodic.

The drug is available in capsules that contain the same amount of active ingredient as in Duspatalin. Due to the fact that the substance dissolves gradually, the effect is achieved for a long time.

When comparing the two medications in detail (Duspatalin or Niaspam), it is worth highlighting three main differences:

1. Manufacturers. Duspatalin is produced by one trusted Dutch company in France, and its analogue is an Indian drug.
2. Minor differences in composition. Of course, studying the instructions, you will notice that their excipients are different. However, the end result in achieving the desired effect is the same. In 75% of patients experienced a significant improvement in their condition.
3. Price. Niaspam is 30% cheaper.

Both drugs are well tolerated and cause minimal side effects.

Effect of taking

Taking Duspatalin allows you to relieve spasm from the smooth muscles of the digestive organs. This occurs by eliminating tension, which provokes pain. Since the intestines contain the most smooth muscles, the drug has the most pronounced effect on it. Elimination of hypertonicity occurs without affecting the peristalsis of the organ. Therefore, feces pass through the intestines without any slowdown. That is, Duspatalin has a targeted effect on the smooth muscles of the intestine, eliminating pain. At the same time, the sphincter of Oddi relaxes, which normalizes the flow of bile and provides an analgesic effect for biliary colic.

If the activity of intestinal smooth muscles is increased, then taking Duspatalin will bring it back to normal. However, the peristalsis of the organ will not be completely stopped, that is, its reflex hypotension will not occur.

After passing the drug through the organs of the digestive system, it enters the intestines, from where it is transported through the bloodstream to the liver. There, certain biochemical reactions are triggered, and the medicinal substance breaks down into metabolites. In this form, it is excreted from the body in urine. The main active substance is not released from the capsule as quickly as from tablets, so the therapeutic effect is extended for 16 hours. Moreover, for this it will be enough to take the drug once.

When should Duspatalin be used?

Indications for taking the drug:

• Spasm-type pain localized in the epigastric region.
• Intestinal and biliary colic.
• Irritable bowel syndrome.
• Disturbances in the functioning of the gallbladder.
• Underwent surgery for resection of the gallbladder.
• Spasms of the smooth muscles of the digestive system against the background of pathologies of other organs (pain due to pancreatitis or cholecystitis).
• Pain caused by a functional disorder of the digestive system.
• Pain, discomfort and spasm in the intestines of a different etiology.

Instructions for use

Duspatalin in tablet form

The drug is not crushed before oral administration, washed down with plain water. You should take the medicine 30 minutes before meals.

It is permissible to take three tablets per day: in the morning, at lunchtime and in the evening. You should stop taking the drug after you feel better, that is, as soon as the pain stops.

The drug should not be discontinued abruptly. You must adhere to the following scheme:

• The first 7 days of withdrawal: take the drug 1 tablet in the morning and at lunch, and drink 1/2 tablet in the evening.
• From days 7 to 14, drink a whole tablet in the morning and evening.
• From days 14 to 21, take a whole tablet in the morning, and 1/2 of the drug in the evening.
• From days 21 to 28, take the drug 1 tablet in the morning.

According to this scheme, leading domestic clinicians who treat diseases of the digestive system suggest discontinuing the drug.

Depending on the specific case, the withdrawal regimen may be reviewed by the treating doctor. So, if after reducing the dose of the drug, the patient feels well, then it is possible to reduce the withdrawal regimen to 14 days. If the patient feels unsatisfactory when the dose is reduced by 1 tablet, then it should be reduced by 1/2 tablet. The patient's well-being should be monitored for at least 2 days.

Most experts recommend reducing the dosage by 1/2 tablet. If there is a need for faster withdrawal of the drug, then after 2 days you can again reduce the dosage by 1/2 tablet. Provided that the patient’s well-being does not deteriorate, this regimen should be continued until the end of the week (counting from the first day of dose reduction). If the patient begins to feel worse, then they switch to the classic scheme of stopping the drug. If the trend is positive, you can continue. That is, at the beginning of each subsequent week you will need to reduce the dose by 1/2 tablet, and after 2 days by another 1/2 tablet.

Abrupt withdrawal of the drug is unacceptable.

Duspatalin capsules

Do not chew the capsules, swallow them whole with plain water. The drug is taken 20 minutes before meals, 2 times a day.

The course of treatment is determined by the complete disappearance of pain and spasms. After this, you can begin to gradually reduce the dosage of the drug. Just like tablets, capsules should not be abandoned abruptly. The dosage should be reduced gradually. Drug withdrawal regimen:

1. For the first 7-14 days, you need to take 1 capsule in the morning.
2. After 7-14 days, you must stop taking the medicine.

To decide how long before you should stop taking the capsules - 7 or 14 days in advance, you need to take a two-day break after taking 1 capsule per day for a week. If during this time your health does not worsen, then you can completely refuse further treatment. Provided that the patient begins to feel worse, the course of therapy is extended for another 7 days, continuing to take 1 capsule in the morning. Then the drug is abandoned altogether.

Overdose

If a person takes too large a dose of the drug, this will lead to increased nervous excitability. To neutralize the effect of the drug, you should rinse your stomach and take activated charcoal orally. In the future, the patient is indicated for symptomatic treatment.

Concomitant use with other drugs

Duspatalin can be taken simultaneously with other medications.

It should be noted that Duspatalin can cause dizziness, so during the therapeutic course it is highly advisable to abandon activities that require increased concentration.

Side effects of Duspatalin and overdose

The drug can be considered safe, but in practice there have been cases when its use provoked the occurrence of side symptoms:

• allergy;
• constipation;
• nausea;
• lowering blood pressure;
• vomit;
• Analytical shock is a rare occurrence.

If suspicious signs appear, you should stop using the drug and consult a specialist for treatment adjustments. If you use a large amount of the drug, an overdose may occur. It is characterized by the following symptoms:

• disruption of the central nervous system;
• disruptions in the functioning of the conduction of the heart muscle;
• development of liver failure;
• development of vascular collapse or severe decrease in pressure;
• dizziness.

An overdose can provoke dangerous consequences, so you should definitely call an ambulance.

Specialists will rinse the stomach and provide restorative therapy. Due to a possible decrease in blood pressure, patients should refrain from driving and work that requires special attention during treatment.

Duspatalin cannot be called an affordable drug. The price for one pack reaches an average of about 450 rubles.

Treatment of children with Duspatalin

Duspatalin is contraindicated for those under 12 years of age.

If the child is already 12 years old, the doctor may prescribe him Duspatalin to eliminate spasms and pain in the intestines and other organs of the digestive system.

Doctors recommend taking the drug for children with the following disorders:

• Heaviness and pain in the abdomen.
• Intestinal colic.
• Abdominal pain due to overeating.
• Abdominal pain caused by nervous tension.
• Irritable bowel syndrome in a child.
• Pain due to dietary errors. So, if a teenager suffers from abdominal pain due to a functional digestive disorder (the child ate a lot of baked goods, fast food or drank a lot of carbonated water), then he should immediately take a Duspatalin capsule. Another capsule is taken in the evening. The next day, treatment can be stopped, provided that your health has stabilized. If the child continues to feel unwell, the drug can be continued. When treatment is delayed for more than 7 days, the drug will need to be discontinued gradually, according to the scheme recommended for an adult.

So, only a doctor can prescribe courses of Duspatalin to a child. As a rule, this treatment regimen is rarely practiced. It is indicated for disturbances in the outflow of bile. Until the child's condition stabilizes, he will need to take two capsules of the drug per day. The withdrawal of the drug lasts for 10 days, during which time the child receives 1 capsule per day. Then they stop taking the medicine altogether.

Sparex or Duspatalin: which is better?

Sparex is a high-quality analogue of Duspatalin. Its active ingredient is mebeverine, but in addition it is equipped with a number of auxiliary components.

Available in the form of capsules containing mebeverine. Each pack contains 10 or 15 tablets.

Used for treatment:

• intestinal colic;
• spasms of the gastrointestinal tract;
• stomach upset.

Contraindications:

• high sensitivity;
• children under 12 years of age;
• pregnancy.

Due to its high quality, the drug is almost as good as Duspatalin. A pack of Sparex will cost three times less - this is the main advantage that the end consumer likes.

Taking Duspatalin during pregnancy

Antispasmodics are prescribed during pregnancy with increased uterine tone. For this purpose, women are prescribed No-shpa. However, when a spasm passes to the smooth muscles of the intestines, it is better to use Duspatalin. With uterine hypertonicity, this drug will be ineffective.

Duspatalin should also be used during pregnancy if spasm of the sphincter of Oddi is observed. This leads to impaired bile flow and abdominal pain.

Studies have been conducted regarding the effects of Duspatalin on the fetus. During the experiments, it was possible to establish that the drug does not have a negative effect on the child in the womb. Therefore, if a doctor recommends taking a drug during pregnancy, then the benefits of its use outweigh all possible risks. Self-prescription of Duspatalin is unacceptable; consultation with a specialist is mandatory.

During pregnancy, you can only take capsules; tablets are strictly contraindicated during this period. You should not combine Duspatalin with other antispasmodics, for example, Papaverine or No-shpa.

The dose for pregnant women per day is 2 capsules. One of them is taken in the morning, and the second in the evening. The course of treatment continues until there is a noticeable improvement in well-being. The drug is discontinued gradually; for this purpose, drink 1 capsule per day for 14 days. After 14 days, the drug is completely stopped.

Duspatalin is often prescribed to women who, even before conceiving a child, suffered from spasms of the sphincter of Oddi. Often this condition accompanies chronic inflammation of the pancreas or occurs after surgery for resection of the gallbladder.

If a woman experiences a spasm of the smooth muscles of the intestine due to emotional stress, or as a result of errors in the diet, then you can take the medicine once. The cancellation scheme is not practiced in this case.

Cheap analogues of Duspatalin: list

Russian analogues of Duspatalin also exist. The tablets contain the important ingredient mebeverine hydrochloride. It is he, being an antispasmodic, that has the desired effect.

However, there are chemical compounds that are similar in mechanism. For example, pinaverium bromide or hymecromone. Thanks to this, you can easily find more affordable products at a lower price in any pharmacy.

The question of what to replace Duspatalin is often asked in pharmacies after hearing the price of the drug. More often, a pharmacist or attending physician may suggest the following analogues:

• No-shpa;
• Dicetel;
• Sparex;
• Odeston;
• Mebeverine;
• Dibazol;
• Trimedat;
• Drotaverine.

It is difficult to say how effective each of them is. To do this, some of them should be considered in more detail.

A list of Russian analogues of Duspatalin is here.

Taking Duspatalin for pancreatitis

Duspatalin is an effective means of eliminating pain due to pancreatitis. This process is always accompanied by a violation of the outflow of pancreatic juice and spasm of the sphincter of Oddi. This problem can be solved by taking Duspatalin.

Due to inflammation of the pancreas, the excretory ducts become spasmodic, and juice is released in large quantities. As a result, the iron begins to digest itself with its own enzymes. To prevent this situation, it is necessary to expand the excretory ducts, relieving the spasm from them. It is Duspatalin that copes with this problem better than other antispasmodics.

The drug is prescribed for minor exacerbation of pancreatitis, which improves the patient’s well-being. For treatment, capsules are used, taking 1 capsule twice a day (morning and evening).

Treatment should continue until the patient's condition has stabilized. Then the drug is gradually withdrawn.

Duspatalin can also be used to prevent exacerbation of inflammation of the pancreas, provided that the disease is chronic. To do this, take 1 capsule 2 times a day for 14 days, and then take one capsule a day for another 7 days. In the future, the use of the drug is completely abandoned.

Side effects of the drug

Side effects when taking the drug occur extremely rarely. A study was conducted involving 8 antispasmodics that are used to treat irritable bowel syndrome. During the experiment, it was possible to establish that Duspatalin, of all drugs, produces fewer side effects.

However, some patients may experience the following problems:

• Dizziness;
• Skin rashes;
• Quincke's edema and facial swelling;
• Allergy in the form of exanthema;
• Skin itching;
• Headache;
• Diarrhea or constipation;
• Nausea.

Duspatalin: contraindications

Being a drug, Duspatalin has a number of contraindications. Tablets should not be used in the following cases:

• individual intolerance;
• pregnancy;
• lactation period;
• children under 18 years of age.

In all other cases, specialists calmly prescribe the medicine.

• Longidaza is sold at a high price, so people often look for cheaper analogues;
• Creon - cheaper analogues (list), which drug is better;
• – cheap analogues of Lamisil.

Analogs

Russian pharmaceutical companies produce analogues and synonyms of the drug Duspatalin. Synonymous drugs contain mebeverine, while analogues have different components, but a similar therapeutic effect.

Drugs synonymous with Duspatalin:

• Niaspam in capsules.
• Sparex in capsules.
• Mebeverine in tablet form.

Duspatalin analogues:

• Trigan in the form of tablets and in the form of injections for intramuscular administration.
• Trimedat tablets.
• Spascuprel in tablets.
• Dibazol tablets.
• Buscopan tablets.
• Bendazole tablets.
• Dicetel in tablets.
• No-spa in tablets.
• Drotaverine tablets.
• Papaverine tablets.

Inexpensive analogues of Duspatalin

Duspatalin analog drugs for the treatment of irritable bowel syndrome at a lower price: Sparex, Trigan and Niaspam.

If we consider inexpensive antispasmodics, then these include: Drotaverine, No-shpa, Papaverine, Dicetel.

Release form, composition

Based on its appearance, the medicine is available in capsules that can have a long-lasting effect.

They are covered with a special gelatinous white shell with markings applied to it. Usually one pack contains 10 or 15 pills in blisters. Carton packaging and instructions are required.

The desired effect is achieved thanks to the active ingredient, which is mebeverine hydrochloride.

Therefore, Duspatalin is often called Meverin. One capsule contains approximately 200 mg of this substance. Consider duspatalin substitutes.

Reviews

Patients who received Duspatalin leave more positive reviews about it. They indicate that the drug allows you to quickly cope with intestinal and stomach colic, eliminate functional digestive disorders, and abdominal pain after overeating.

Patients with irritable bowel syndrome note that Duspatalin makes it possible to get rid of pain, regulate bowel movements, and reduce bloating. Patients receiving antibacterial treatment often suffer from dysbiosis, which causes severe abdominal pain. Duspatalin copes well with this problem. The pain begins to subside within half an hour after the first dose of the drug. Moreover, the capsules have a prolonged action.

Duspatalin has positive reviews from patients suffering from inflammation of the pancreas and gallbladder. The drug quickly relieves spasm, which leads to normalization of the patient's condition. Even with exacerbation of pancreatitis and cholecystitis, pain can be completely managed within 2-3 days. Patients with chronic pathologies take Duspatalin for preventive purposes and note its high effectiveness in preventing the development of relapses.

Negative reviews about Duspatalin are extremely rare. They boil down to the fact that the drug did not eliminate pain during exacerbation of inflammation of the pancreas or gall bladder. However, you should not expect a lightning-fast solution to the problem, since pain relief should take 2-3 days, not several hours. Therefore, such reviews can be considered not entirely justified.

Some people become disillusioned with the drug and take it inappropriately. Patients often indicate that Duspatalin did not help cope with gastritis or stomach ulcers. But this medicine is not intended to treat these diseases. Duspatalin is an antispasmodic and its main effect is to reduce pain.

Reviews from experts

Practicing gynecologists note that Duspatalin allows you to get rid of intestinal colic in pregnant women, regardless of the nature of their occurrence.

Therapists and gastroenterologists indicate that Duspatalin can be successfully used in the treatment of irritable bowel syndrome, pancreatitis, cholecystitis, as well as to get rid of negative symptoms that arise from functional digestive disorders.

Doctors indicate that Duspatalin cannot be used as a monocomponent for pancreatitis. The drug should be part of a complex therapy regimen. Otherwise, it will not be possible to achieve recovery.

What to choose: Duspatalin or Trimedat?

Trimedat and Duspatalin have a similar therapeutic effect, since both of these drugs relieve muscle spasm. The difference is that Trimedat has a wider spectrum of action compared to Duspatalin, so it is used to treat severe pathologies of the digestive system. If the patient has chronic pancreatitis or cholecystitis, or an exacerbation of the disease occurs, then Duspatalin can be taken.

In any case, the doctor must prescribe this or that drug, based on the individual characteristics of the patient’s body. Trimedat is more suitable for some patients, and Duspatalin for others.

What to choose: Duspatalin or Dicetel?

Dicetel has a less pronounced effect compared to Duspatalin. The drug will not completely relieve spasm from the ducts of the pancreas and gallbladder, which occurs against the background of inflammation of these organs. In addition, taking Dicetel is associated with a greater risk of developing allergic reactions than taking Duspatalin.

However, if a person has a digestive disorder caused by an irrational approach to nutrition, Dicetel can be used. In this case, the drug will cope well with the task of pain relief.