Buy Calcium D3 chewable tablets orange No. 100 Implovit in pharmacies

Buy Calcium D3 chewable tablets orange No. 100 Implovit in pharmacies

Release form:

Chewable tablets weighing 1700.0 mg ±10%.

Compound:

calcium carbonate, sucrose, talc (anti-caking agent), calcium salt of stearic acid (anti-caking agent), potato starch, natural orange flavor (aromatics, vegetable oil (rapeseed) or aromatics, maltodextrin, gum arabic, rosemary extract (antioxidant) , or aromatics, maltodextrin, gum arabic, antioxidant ascorbyl palmitate + tocopherol), cholecalciferol (vitamin D3).

The daily dose contains:

1 - according to MP 2.3.1.2432-08 “Norms of physiological needs for energy and nutrients for various groups of the population of the Russian Federation”; 2 - according to TR CU 022/2011 “Food products regarding their labeling” (Appendix 2); * - does not exceed the upper permissible level of consumption according to the “Unified Sanitary-Epidemiological and Hygienic Requirements for Goods Subject to Sanitary-Epidemiological Surveillance (Control)” (Chapter II, Section 1, Appendix 5).

Application area:

as a biologically active food supplement - an additional source of calcium and vitamin D3.

Recommendations for use:

chewing immediately after eating

- children 3 to 7 years old, 1 tablet 1 time per day; - children over 7 years old, 1 tablet 2 times a day; - adults: 1-2 tablets 2 times a day.

Duration of admission:

1 month. If necessary, the reception can be repeated.

Contraindications:

individual intolerance to product components, pregnancy, breastfeeding, carbohydrate metabolism disorders (including diabetes). It is recommended to consult a doctor before use. Before use by children, it is necessary to consult with a pediatrician; children under 14 years of age should take it by agreement and under the supervision of a pediatrician.

Calcium (Ca)

- a common macronutrient in the human body, which is the main building material of bones (99% of calcium is contained in bones), teeth, and an important component of hair and nails. Calcium also ensures the normal functioning of the body as a whole.

At different periods of life, the need for calcium may be different. For example, in adolescence, consuming a sufficient amount of this element is very important due to the intensive growth of the skeleton; for example, with a lack of calcium, children begin to lag in growth.

During menopause and postmenopause, calcium helps prevent fractures, this is especially important for those who are not receiving hormone replacement therapy.

As a result of decreased bone density, joint pain may occur, and in older people, due to increased bone fragility, the risk of fractures increases. As calcium deficiency increases, bone mineralization decreases, which can lead to a pathological decrease in bone density, its rarefaction with loss of natural strength.

In the human body, a lack of calcium can manifest itself in the form of deterioration in the condition of teeth, hair and nails, as well as increased fatigue, general weakness and a decrease in usual ability to work. At the same time, muscle spasms, nervousness, and irritability may occur.

The Key Role of Vitamin D3

, which is part of “Calcium D3”, is to maintain calcium-phosphorus balance in the blood. Vitamin D3 is important for the normal absorption of calcium in the intestines, as well as for ensuring the strength of teeth and bones.

Keep

in a place protected from direct sunlight and out of reach of children, at a temperature not exceeding 25 °C.

Best before date:

3 years.

Calcium D3 Meligen caps. 570 mg No. 100 with vitamins

Calcium - takes part in the formation of bone tissue, mineralization of teeth, blood clotting processes, muscle contractions, and is necessary to maintain stable activity of the cardiovascular and nervous systems.

Colecalciferol (vitamin D3) regulates the exchange of calcium and phosphorus in the body, enhances the absorption of calcium in the intestine, reduces resorption and increases bone density.

Vitamin C – is involved in collagen synthesis and redox processes, regulates carbohydrate metabolism, blood clotting, synthesis of steroid hormones, ensures tissue regeneration, and increases the body’s resistance to infections. It gives a particularly pronounced effect in combination with other vitamins.

Vitamin A – improves immunity, promotes normal metabolism, regulates the functions of cellular and subcellular membranes, plays an important role in the formation of bones and teeth, is necessary for the growth of new cells, improves vision, ensures the preservation of fertility, slows down the aging process, rejuvenates the skin, keeping it elastic , elastic and smooth.

Vitamin E - has a pronounced antioxidant and immunostimulating effect, improves circulation and ensures normal blood clotting, promotes the healing of skin damage, maintains the health of nerves and muscles, relieves leg cramps, strengthens capillary walls, prevents anemia, and is good for women's health.

Vitamin B1 (thiamine) has a calming effect on the nervous system, promotes wound healing, actively participating in cellular metabolism, and has analgesic properties.

Vitamin B2 (riboflavin) intensifies metabolic processes in the body, participating in the metabolism of proteins, fats and carbohydrates, and is necessary for the formation of red blood cells and antibodies, for respiration and cell growth. It facilitates the absorption of oxygen by the cells of the skin, nails and hair, improves the condition of the organs of vision, reduces eye fatigue and plays a major role in the prevention of cataracts; has a positive effect on the mucous membranes of the digestive tract, minimizing the negative effects of toxins on the respiratory tract.

Vitamin B5 (calcium pantothenate) is necessary for the metabolism of fats, carbohydrates, amino acids, the synthesis of vital fatty acids, cholesterol, histamine, acetylcholine, and hemoglobin.

Vitamin B6 (pyridoxine) plays an important role in metabolism, is necessary for the normal functioning of the central and peripheral nervous system, reduces cholesterol and lipid levels in the blood, improves myocardial contractility, promotes the conversion of folic acid into its active form, and improves lipid metabolism.

Vitamin B7 (biotin) stabilizes blood sugar, helps absorb protein, participates in the breakdown of fatty acids and fat burning; it can be called a beauty vitamin for skin, hair and nails.

Vitamin B9 (folic acid) is involved in the synthesis of amino acids, nucleic acids, purines and pyrimidines, and in choline metabolism. During pregnancy, it protects the body from the effects of teratogenic factors.

Vitamin B12 (cyanocobalamin) has a pronounced lipotropic effect, prevents fatty infiltration of the liver, increases oxygen consumption by cells during acute and chronic hypoxia.

Vitamin PP (nicotinamide) regulates redox processes in the body.

Calcium is the building material of your body

In order to function fully, the body needs vitamins and minerals. They, directly or indirectly, regulate many of the biochemical processes occurring in it. Calcium performs many functions and is part of the tissues of our body.

Why is calcium so important?

• are “bricks” for the construction of bones and teeth;
• is part of nails, hair, soft tissues, blood plasma; • an important component of the blood coagulation system (if there is a shortage of it, it is difficult to stop bleeding); • ensures muscle contraction (including heart muscle!); • participates in the transmission of nerve impulses; • affects the activity of hormones; • affects the permeability of cell membranes to potassium and sodium. With a balanced diet, we meet the necessary calcium requirement with food. But if it is insufficiently supplied from food, calcium deficiency can develop, which leads to serious disruptions in the functioning of the body.

How do you know if calcium deficiency is developing?

Since this mineral is involved in many processes, symptoms of its deficiency can be varied: • increased fatigue, constant general weakness, sleep disturbances;
• brittle dull hair, flaking nails; • pain and cramps in the muscles of the arms and legs, soreness around the joints; • bleeding gums, frequent nosebleeds; the appearance of bruises on the skin; • increased sensitivity of teeth to cold and hot, quickly appearing and developing caries; • immunity decreases (frequent colds appear, which are more severe and take longer to treat); • with severe calcium deficiency, bone mineralization decreases, children begin to grow slower, adults develop characteristic joint pain, and osteoporosis occurs. Osteoporosis

(translated as “porous bone”) is a skeletal disease accompanied by a decrease in mineral density and a change in the quality of bone tissue, which leads to an increase in bone fragility and the risk of fractures. Osteoporosis is one of the most common skeletal diseases in women over 50 years of age. Osteoporosis goes unnoticed for many years; its first manifestation may be a crack or fracture of the bone. The main measure in the fight against osteoporosis is prevention. It is very important to lead an active lifestyle, give up smoking, excessive coffee, alcohol, and unbalanced diets. It should also be remembered that a lack of calcium during growth leads to a decrease in peak bone mass, which can cause fractures in the future. It is known that for good absorption of calcium in the intestines and its fixation in bone tissue, a sufficient amount of vitamin D3 is necessary. Optimal intake of calcium and vitamin D3 is an important part of the prevention of osteoporosis, which should be carried out throughout life, with special attention should be paid to it in adolescents and the elderly.

What should you do if you have a calcium deficiency?

• Nutrition correction: it is necessary to increase the consumption of foods such as hard cheeses, kefir, milk, cottage cheese, yoghurts, since the main source of calcium is dairy products.
There is also a lot of it in pumpkin, sesame, basil, fish, and beans. • Reduce tea and coffee consumption as they reduce calcium absorption. • Additionally use vitamin D3 and magnesium, as they significantly improve the absorption and absorption of calcium. • Take medications containing calcium and vitamin D3. If there is insufficient calcium intake from food (for example, with intolerance to dairy products, malnutrition) or an increased need for it (in children and adolescents, during pregnancy, breastfeeding), it is additionally recommended to take calcium supplements based on the daily requirement - 1000-1500 mg. Taking care of your health, the pharmaceutical company "Minskinterkaps" (Republic of Belarus) produces vitamin and mineral complexes "Calcium-D3-MIK"

and
“Calcium-D3-MIK-forte”
whose active ingredients are calcium carbonate and vitamin D3. An important advantage of the drugs is their convenient capsule form, which allows for precise dosing of the drug. Pharmaceutical raw materials for the production of these medicines are purchased from the European Union.

"Calcium-D3-MIK" and "Calcium-D3-MIK forte" are indicated for:

• states of calcium and vitamin D3 deficiency in the body associated with an unbalanced diet;
• increased body need for calcium and vitamin D3 during pregnancy and breastfeeding, as well as in children over 12 years of age during the period of intensive growth; • for the prevention of osteoporosis and its complications (bone fractures), as an addition to any specific therapy for osteoporosis. The dosage regimen for children under 12 years of age is determined by the doctor. Medicines "Calcium-D3-MIK-forte"

and
“Calcium-D3-MIC”
increase bone tissue density and promote bone mineralization. The recommended dosage regimen is 2-3 capsules 2 times a day. When used to replenish calcium and vitamin D3 deficiency, the average duration of treatment is at least 4-6 weeks. The number of repeat courses during the year is determined individually.

It is especially important to take Calcium-D3-MIC

and
Calcium-D3-MIC-forte
for postmenopausal women, because they are very vulnerable to calcium deficiency: due to a deficiency of sex hormones, their bone loss accelerates. These drugs are also used as an addition to the complex treatment of osteoporosis. In addition, calcium is necessary for the mineralization of teeth, the regulation of nerve conduction and muscle contraction.

th, and vitamin D3 stimulates the development of the immune system, the functional activity of the cardiovascular system and the gastrointestinal tract. When used for prevention and in complex therapy of osteoporosis, the duration of treatment is determined by the doctor individually.

Taking medications Calcium-D3-MIC

and
Calcium-D3-MIC forte
helps you provide your body with calcium and vitamin D3 in sufficient quantities, improve your health, maintain the strength of your skeleton, prevent fractures due to fragile bones and lead an active life in the future.

Has contraindications and side effects. Before using the medicine, read the instructions. Be healthy!

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Calcium-D3-MIK

Pharmacodynamics

Calcium-D3-MIC is a combination drug that regulates the metabolism of calcium and phosphorus.

Calcium is a vital mineral element necessary to maintain the balance of electrolytes in the body and the adequate functioning of regulatory mechanisms. Calcium carbonate is involved in the formation of bone tissue, is necessary for the mineralization of teeth, regulation of nerve conduction, muscle contractions, maintaining stable cardiac activity and is a component of the blood coagulation system. Calcium (in ionized form and in the form of complexes) plays a key role in cell division and differentiation, conduction of nerve impulses and in the contraction-relaxation cycle (together with tropin) of smooth and striated muscles, transmembrane ion reactions involving selective calcium channels, activity neuroselective organs, the production and effects of a number of hormones, enzymes and other protein, as well as non-protein biologically active substances. The participation of calcium in such diverse processes is explained by its universal function as a secondary messenger (transmitter) that transmits and implements a biological signal in various types of cells.

Vitamin D3 stimulates the absorption of calcium and phosphorus in the intestines, the reabsorption of calcium and phosphorus in the kidneys, the transport of calcium through membranes and cells, the development of the immune system, cell proliferation and differentiation, the synthesis of lipids and a number of hormones, the functional activity of the cardiovascular system and gastrointestinal tract , reduces the level of parathyroid hormone in the blood. It is necessary for the normal functioning of the parathyroid glands and takes part in the synthesis of ATP.

Vitamin D3 and its active metabolites have a multifaceted effect on bone tissue: they increase the absorption of calcium in the intestine, stimulating the synthesis of calcium-binding proteins; increase calcium reabsorption in the renal tubules; activate bone remodeling processes by increasing the synthesis of collagen I and matrix proteins, by activating the synthesis of osteoblasts; improve bone quality by influencing osteoclast activity; regulate the secretion of parathyroid hormone by two mechanisms: directly suppressing the proliferation of parathyroid cells and through increasing the level of calcium in the blood; stimulate the differentiation of cells - precursors of bone and cartilage tissue; have a positive effect on neuromuscular conduction through the regulation of calcium channels and protein kinase A activity.

The use of a combination drug containing calcium and vitamin D3 is justified, since vitamin D3 increases the absorption of calcium in the intestine and the combined use of calcium and vitamin D3 prevents an increase in the production of parathyroid hormone (PTH), which is a stimulator of increased bone resorption (leaching of calcium from the bones).

Thus, Calcium-D3-MIC regulates the exchange of calcium and phosphates, reduces resorption and increases bone density, compensates for the lack of calcium and vitamin D3 in the body, enhances the absorption of calcium in the intestines and the reabsorption of phosphates in the kidneys, and promotes bone mineralization.

Pharmacokinetics

Calcium. Calcium absorption occurs in the duodenum, jejunum and colon. This process is carried out with the participation of two mechanisms: active absorption and passive diffusion, with the participation of which less than 10% of the element supplied with food is absorbed. The main regulator of active absorption is the vitamin D metabolite, calcitriol, which stimulates the biosynthesis of calcium-binding proteins in intestinal enterocytes. After being absorbed into the systemic circulation, calcium is distributed among organs and systems and primarily enters bone tissue.

Under physiological conditions, the excretion of calcium from the body (except for the part excreted in feces that is not absorbed in the intestine) is approximately 250–300 mg per day, which includes 140–180 mg that has not undergone reabsorption in the kidneys and enters the urine, as well as 80–100 mg, excreted into the intestines with bile and pancreatic secretions.

Calcium absorption increases during pregnancy and lactation.

Penetrates the placental barrier and is excreted in breast milk.

Cholecalciferol. Absorption of cholecalciferol occurs in the small intestine in the presence of bile. Usually 50-70% of the taken dose of the vitamin is absorbed. Incomplete absorption is observed with obstructive jaundice and severe steatorrhea.

The maximum concentration is reached after 8-18 hours. From the bloodstream, about 70% of vitamin D3 is absorbed by the liver, where it is metabolized. The resulting metabolite (25-hydroxycholecalciferol) is transported to the kidneys, where the formation of biologically active compounds occurs, among which 1,25-dihydroxycholecalciferol (1,25 (OH)2 D3) and 24,25-dihydroxycholecalciferol (24, 25 (OH)2D3).

The metabolism of cholecalciferol is disrupted in chronic renal failure, with the prescription of protein synthesis inhibitors (actinomycin, glucocorticoids), with long-term use of phenobarbital and diphenine.

Vitamin D3 has cumulative properties. It accumulates in the liver in non-parenchymal cells, from where it is transported to hepatocytes, where it is metabolized.

Penetrates the placental barrier and is excreted in breast milk.

T1/2 from blood plasma is up to several days and may be longer in case of impaired renal function.

In elderly patients, renal function may decrease, which should be taken into account when dosing the drug.

In patients with chronic liver failure, hypocalcemia may be a consequence of a decrease in the synthesis in the liver of 25-hydroxy-cholecalciferol as a substrate for the formation of 1,25-dihydroxy-cholecalciferol in the kidneys, that is, a vitamin D hormone that increases the intestinal absorption of ionized calcium.

Chronic renal failure is accompanied by a decrease in the synthesis of vitamin D hormone, which in some patients causes hypocalcemia. In patients with nephrotic syndrome, urinary loss of 25-hydroxycholecalciferol leads to hypocalcemia. Hypocalcemia due to loss of 25-hydroxycholecalciferol can be caused by a blockade of its physiological circulation between the intestinal lumen and the liver, due to a decrease in intestinal absorption.