Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Vitamins Kvadevit normalize metabolism in the body. The dose of each component is close to the physiological norm.
- Vitamin A is necessary for the construction of epithelial cells, ensures the function of the skin and mucous membranes, and the organ of vision. Supports the synthesis of immunoglobulins.
- Vitamin E is a physiological antioxidant that protects cell membranes from damage, prevents hemolysis, stimulates the synthesis of many proteins, and has a positive effect on the function of the gonads and nervous tissue.
- Vitamin B1 is involved in carbohydrate metabolism and is necessary for the functioning of the nervous system.
- Vitamin B6 is involved in protein metabolism, without it the synthesis of neurotransmitters is not possible.
- Vitamin B2 is involved in cellular respiration and redox reactions.
- Vitamin B12 is a growth factor, is involved in the synthesis of amino acids, and is necessary for the processes of red blood cell maturation, hematopoiesis in general, and for the metabolism of folic acid.
- Folic acid is involved in the synthesis of amino acids and choline metabolism. It is necessary for the normal course of erythropoiesis and, together with vitamin B12, stimulates it.
- Rutoside is an antioxidant. Reduces capillary fragility, inhibits the effect of hyaluronidase. Promotes the accumulation of ascorbic acid in tissues.
- Nicotinamide takes part in tissue respiration, lipid and carbohydrate metabolism. It is part of the glucose tolerance factor.
- Vitamin C is necessary for the growth of bones, cartilage, skin, capillary endothelium, for the formation of hemoglobin and the maturation of red blood cells. Necessary for the functioning of the nervous system.
- Glutamic acid is a material for the synthesis of amino acids in the body. Improves protein and carbohydrate metabolism, energy supply to the brain. The presence of glutamic acid improves nervous activity and motor activity. Promotes the release of ammonia from the body.
- Methionine is an essential amino acid necessary for growth and the processes of detoxification of xenobiotics, activation of hormones, enzymes and proteins. Prevents fatty liver degeneration.
- Phytin is an organic phosphorus compound. Stimulates hematopoiesis, affects bone growth and helps improve the function of the nervous system.
- Calcium pantothenate is necessary for the synthesis of ATP and antibodies, the absorption of potassium and vitamin E. Participates in the processes of epithelial regeneration.
- Potassium is involved in electrolyte metabolism and nerve impulse transmission. Activates muscle work, including the heart muscle, regulates vascular tone.
- Copper is involved in anabolic processes, iron metabolism and the formation of red blood cells. Strengthens the walls of blood vessels.
Pharmacokinetics
Not studied.
Side effects
In recommended doses, the drug is well tolerated and rarely causes side effects, which are usually associated with individual intolerance to one of the components of the drug.
From the immune system: in persons with hypersensitivity, allergic reactions are possible, including anaphylactic shock, angioedema, hyperthermia; bronchospasm in persons with hypersensitivity to vitamins A, C, group B.
From the skin and subcutaneous tissue: rash, urticaria, itching, redness of the skin.
From the digestive tract: dyspeptic disorders, nausea, vomiting, diarrhea, epigastric pain, belching, constipation, possibly increased secretion of gastric juice.
From the nervous system: headache, dizziness, increased excitability, drowsiness.
Others: urine may turn yellow, hyperhidrosis, blurred vision.
With long-term use of the drug in high doses, irritation of the mucous membrane of the digestive tract, arrhythmias, paresthesia, hyperuricemia, transient increase in the activity of AST, LDH, alkaline phosphatase, decreased glucose tolerance, hyperglycemia, impaired renal function, dryness and cracks on the palms and soles, hair loss are possible. , seborrheic rashes.
Analogs
Level 4 ATC code matches: Optix
Antioxycaps
Multi-Tabs Immuno Kids
Multi-Tabs Immuno Plus
Multi-Tabs Active
Coenzyme Q10
Doppelhertz Energotonic
Complement for women 45 Plus
Vitamax
Revalid
Gerimaks
Biovital
Vitrum Lift-Skin Q10
Vitrum Vision
Vitrum Beauty
There is no vitamin complex that completely replicates the composition of Kvadevit. You can name an analogue of Kvadevit in action - Complivit , as well as Alvitil , Revit , Pangexavit .
special instructions
When using the drug, it is necessary to observe the dose and duration of the course.
If there is no therapeutic effect or adverse reactions occur, you should consult your doctor for advice regarding further use of the drug.
Urine may turn yellow, which is a safe symptom and is explained by the presence of riboflavin in the drug.
The drug is prescribed with caution for severe liver damage, gastric and duodenal ulcers, patients with nephritis, chronic pancreatitis, cholelithiasis, cardiac decompensation, coronary artery disease, diabetes mellitus, patients with neoplasms (except for cases accompanied by megaloblastic anemia), urolithiasis.
When using Kvadevit, like other multivitamin preparations, you need a complete protein diet that promotes better absorption and metabolism of vitamins, especially water-soluble ones.
Kvadevit is not recommended to be prescribed together with other vitamins and preparations containing microelements, due to a possible overdose of the latter.
Use during pregnancy and lactation. During pregnancy and breastfeeding, the drug is taken only on the recommendation of a doctor.
The dose of vitamin A should not exceed 5000 IU for pregnant women and women planning pregnancy.
Retinol should not be taken in high doses (over 10,000 IU) during breastfeeding due to the risk of developing hypervitaminosis A in infants.
Children. This dosage form is not intended for use in children under 14 years of age.
The ability to influence reaction speed when driving vehicles or working with other mechanisms. There is no data on the effect of the drug on the ability to drive a car or operate complex machinery.
Reviews about Kvadevit
This vitamin complex is designed primarily for elderly people. It has a lipid-lowering effect: it reduces the atherogenic index and reduces cholesterol in patients with coronary artery disease . It is also used to prevent aging. Consumers note an acceptable price compared to imported drugs. Some people are not satisfied with the frequency of administration - three times a day, since they can forget about taking it.
Many people, including middle-aged people, take these vitamins to prevent diseases and speak positively about them.
“For the second winter in a row, I’ve been taking Kvadevit for preventive purposes—I’ve never gotten sick.”
“This is not the first time I’ve taken Kvadevit and I notice that there is an incredible increase in strength.”
“I noticed that after taking these vitamins my nails stopped peeling.”
However, vitamin complexes with a limited content of minerals ( Kvadevit Revit , Undevit ) have recently been losing popularity, as consumers have a tendency to purchase drugs with the maximum possible number of useful components - a full range of minerals and trace elements.
Indications
The drug is indicated as a preventive and therapeutic agent:
- with mental and physical stress;
- with hypovitaminosis, the body’s increased need for vitamins and microelements due to an unbalanced diet, adherence to a special diet, gastrointestinal disorders;
- during the recovery period after serious illnesses, operations, injuries and stressful situations;
- to increase the overall resistance of the body and prevent infectious diseases during epidemics (such as, for example, influenza);
- to stimulate the healing of wounds and burns;
- in order to reduce toxicity and reduce the severity of side effects during antibiotic therapy, during and after chemotherapy;
- in the complex treatment of atherosclerosis, cerebrovascular accidents and cardiovascular failure.
Kvadevita price, where to buy
At the moment, it is not possible to buy Kvadevit in Moscow pharmacies. If you are interested in domestic vitamin preparations that are affordable, then in the pharmacy chain you can buy Revit 100 tablets for 34-65 rubles. and Undevit 50 tablets for 45-66 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
LuxPharma* special offer
- Kvadevit tab.
N60 1800 rub. order
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Pharmacy24
- Kvadevit No. 30 tablets PAT "Kiev Vitamin Plant", Kiev, Ukraine
74 UAH. order - Kvadevit N60 tablets PAT "Kiev Vitamin Plant", Kiev, Ukraine
134 UAH order
Application
The drug is taken orally after meals.
For preventive purposes, Kvadevit is prescribed to adults and children over 14 years of age, 1 tablet per day, for elderly people - 1 tablet 2 times a day. The duration of the preventive course is 1–2 months.
For therapeutic purposes, use 1 tablet 3 times a day. The course of treatment is 3–4 weeks. Repeated courses are carried out after a 3-month break.
During pregnancy and breastfeeding, the drug is used exclusively as prescribed by a doctor. In the first trimester - no more than 1 tablet per day, in the second and third trimester - no more than 2 tablets per day. During breastfeeding, take 1 tablet per day for preventive purposes, and 1 tablet 2 times a day for therapeutic purposes.
Composition for 1 tablet
- taurine - 200 mg
- L-tyrosine – 100 mg
- L-carnitine – 50 mg
- nicotinamide (B3) – 20 mg
- vitamin E – 15 mg
- zinc - 15 mg
- vitamin B6 - 5.4 mg
- calcium D-pantothenate (B5) – 5 mg
- vitamin B2 - 4.8 mg
- vitamin B1 - 3.9 mg
- copper - 1000 mcg
- vitamin A - 750 mcg
- folic acid (B9) - 400 mcg
- iodine - 150 mcg
- selenium - 70 mcg
- chromium - 50 mcg
- biotin (B7) – 30 mcg
- vitamin B12 - 3 mcg
Note!
Description of the drug Kvadevit table. p/o No. 60 on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
Interactions
The drug is not recommended to be taken simultaneously with other multivitamins, since an overdose of the latter in the body is possible.
Vitamins A and E mutually enhance the effect and are synergists. Retinol reduces the severity of the anti-inflammatory effect of glucocorticoids. It should not be taken simultaneously with nitrites and cholestyramine, as they interfere with the absorption of retinol.
Vitamin A should not be given with retinoids as the combination is toxic.
Preparations containing iron inhibit the effect of vitamin E. Vitamin E cannot be used together with preparations of iron, silver, products that have an alkaline environment (sodium bicarbonate, trisamine, etc.), indirect anticoagulants (dicoumarin, neodicoumarin, etc.). ). Alpha-tocopherol acetate enhances the effect of steroidal and non-steroidal anti-inflammatory drugs (sodium diclofenac, ibuprofen, prednisolone, etc.).
Vitamin C enhances the effect of sulfonamides (risk of crystalluria), penicillin, increases iron absorption, reduces the effectiveness of heparin and indirect anticoagulants. The absorption of vitamin C is reduced when used simultaneously with oral contraceptives.
Vitamin B6 weakens the effect of levodopa, prevents or reduces the severity of toxic manifestations that are noted when using isoniazid and other anti-tuberculosis drugs.
Thiamine, influencing polarization processes in neuromuscular synapses, can weaken the curare-like effect.
PAS, cimetidine, calcium supplements, alcohol reduce the absorption of vitamin B12.
Folic acid reduces plasma concentrations of phenytoin; with other antiepileptic drugs, a mutual decrease in clinical effectiveness is possible.
Riboflavin is incompatible with streptomycin and reduces the effectiveness of antibacterial drugs (oxytetracycline, doxycycline, erythromycin, tetracycline and lincomycin).
Tricyclic antidepressants, imipramine and amitriptyline inhibit the metabolism of riboflavin, especially in cardiac tissue.
