Motrin belongs to the group of non-steroidal medications that exhibit a pronounced anti-inflammatory effect. It also has an antipyretic and anesthetic effect. Like all NSAIDs, this drug acts on the body’s tissue hormones – prostaglandins. Motrin slows down the synthesis of these compounds, preventing the development of an inflammatory response and pain. The medication is prescribed to eliminate pain of any nature.
Indications for use
According to the instructions, Motrin is used mainly to relieve mild or moderate pain that occurs with the following pathologies:
- symptomatic treatment of tendovaginitis, bursitis and other diseases of the musculoskeletal system;
- inflammatory processes and pain after surgery in gynecology, traumatology, surgery and orthopedics;
- migraine, dental and menstrual pain, adnexitis;
- myalgia and neuralgia;
- increased temperature during influenza and ARVI;
- pain syndrome due to traumatic injuries of the limbs (bruise, sprain).
The medication is used comprehensively as part of the treatment of infectious pathologies of the ENT organs to eliminate pain in otitis media, rhinitis, tonsillitis, and pharyngitis. The medicine reduces symptomatic manifestations without affecting the course of the underlying disease.
Midodrin (Midodrin) description and instructions for use of the drug.
Drug name:
Midodrin
Name of the drug: Midodrin
Indications for use: Midodrine is used for various types of hypotension (low blood pressure): for orthostatic hypotension (a drop in blood pressure when moving from a horizontal to a vertical position) caused by a violation of the tone of the sympathetic nervous system, for idiopathic (of unclear origin) orthostatic hypotension, secondary hypotension associated with infectious diseases, injuries, and the use of medications.
Pharmacological action: In terms of chemical structure and pharmacological properties, midodrine is close to adrenaline-like sympathomimetic substances. It has a vasoconstrictor and pressor (increasing blood pressure) effect. Like norepinephrine and mesatone, it stimulates mainly alpha-adrenergic receptors, with little effect on beta-adrenergic receptors; does not have a significant effect on heart rate, contractility of the myocardium (heart muscle), or on the muscles of the bronchi. The vasoconstrictor effect develops more slowly and more evenly than with the use of norepinephrine and mesatone.
Midodrin (Midodrine) instructions for use and dosage: Midodrine is used orally and intravenously. Orally, 1 tablet containing 2.5 mg is usually prescribed 2 (less often 3) times every day or 7 drops of a 1% solution 2 times every day. When a clinical effect is achieved and for long-term therapy, 1/2 tablet (1.25 mg) is prescribed 2 times every day or 3 drops of a 1% solution 2 times every day. In some cases, 2 tablets (5 mg) are initially prescribed 2 times every day. If necessary, the contents of one ampoule (5 mg) are administered intravenously 2 times every day.
Mulimen description and instructions for use of the drug.
Midodrin contraindications: The drug is contraindicated in hypertension (high blood pressure), pheochromocytoma (adrenal tumors), spastic and obliterating diseases of peripheral vessels (diseases of blood vessels with narrowing of their lumen due to spasm or atherosclerotic deposits), thyrotoxicosis (thyroid disease), adenoma (benign tumor) of the prostate gland, angle-closure glaucoma (increased intraocular pressure). Caution should be exercised when treating patients with heart failure and arrhythmia, impaired renal function. Midodrine should not be prescribed during pregnancy.
Midodrin side effects: Treatment with midodrine must be carried out under the control of blood pressure and other hemodynamic parameters. If the dose is exceeded or individual hypersensitivity is possible, a hypertensive reaction (a rise in blood pressure above normal), bradycardia (rare pulse), increased sweating, pilomotor reaction (“goose bumps”), and disturbances (delayed or increased frequency) of urination are possible.
Release form: Tablets containing 0.0025 g (2.5 mg) of midodrine in a pack of 20 or 50 pieces; 1% solution in bottles of 10; 20 or 25 ml; 0.25% solution in ampoules of 2 ml (5 mg per ampoule) in a pack of 5 ampoules.
Requip - instructions, composition, dosage, side effects of use
Synonyms: Gutron, Alfamin, Hypertane, Midamin, etc.
Storage conditions: List B. Protected from light.
Additionally: Mezaton is also included in the products Coldrex, Rhinopront, phenylephrine + tramazolin, Coldex Teva, Coldex powders.
Attention! To use the drug "Midodrin (Midodrin)" you should obtain a detailed and complete consultation with your doctor. The instructions are provided solely for familiarization with “ Midodrin (Midodrin) ”.
How to use Motrin: dose and duration of therapy
This remedy is prescribed for both adults and children (from 12 years of age). The tablets must be swallowed without chewing, and then washed down with the required amount of water. The drug can be taken directly during meals.
The smallest dose of Motrin for pain relief is 2 tablets per day (500 mg). If necessary, the doctor can increase the dosage to 1000-2000 mg, which corresponds to 4-8 tablets per day. The average dose of the medicine is 500-1000 mg (2-4 tablets) per day.
For migraines, it is recommended to drink this medication in an amount of 500 mg 2 times a day. Therapy is stopped if the drug is ineffective and the frequency of pain attacks persists for 4-6 weeks.
To eliminate gynecological or menstrual pain, at the beginning of treatment, 1 tablet is prescribed 2 times a day. But if pain persists, the dosage is increased by taking 1 lozenge 3-4 times a day.
Elimination of pain due to pathologies of the musculoskeletal system requires the use of 1-2 tablets twice a day. As an antipyretic, this medication is used in the amount of 2-3 lozenges per day. The duration of therapy without consulting a specialist should not exceed 5 days.
Gutron 2.5 mg suspension. 30 ml (Midodrine)
Manufacturer: Lusofarmaco (Nicomed Austria GmbH)
Group affiliation: Alpha adrenergic agonist
Description of the active substance (INN): Midodrine
Dosage form: tablets, drops
Indications: Orthostatic hypotension (with reactions such as sympathicotonia and asympathicotonia), idiopathic orthostatic hypotension, secondary orthostatic hypotension, arterial hypotension (against the background of psychoactive drugs, during convalescence after surgery and childbirth), secondary hypotension in infectious diseases, arterial hypotension during weather changes , urinary incontinence (involuntary urination due to bladder sphincter dysfunction).
Contraindications: Hypersensitivity, arterial hypertension, pheochromocytoma, occlusive arterial diseases, spasm of peripheral arteries, closed-angle glaucoma, prostatic hyperplasia (with urinary retention), mechanical obstruction of the urinary tract, thyrotoxicosis. Caution. CHF, arrhythmias, renal and/or liver failure, pregnancy, lactation (prescription is possible only under strict indications).
Side effects: From the cardiovascular system: increased blood pressure, incl. in the “lying down” position, facial hyperemia, bradycardia. From the urinary system: disturbance of urination (frequency or retention). From the nervous system: headache, dizziness, insomnia, drowsiness, asthenia, paresthesia. From the digestive system: heartburn, dry mouth, nausea, dyspeptic disorders, flatulence. From the skin: increased sweating, pilomotor reaction (“goose bumps”), itching, chills. Overdose. Symptoms: bradycardia, increased blood pressure, chills, goose bumps, urinary retention. Treatment: induction of vomiting, gastric lavage, atropine in therapeutic doses, phentolamine.
Directions for use and doses: Doses depend on the severity of clinical manifestations and are selected individually. Orally, usually prescribed 2.5 mg 2 times a day (1 tablet or 7 drops of a 1% solution 2 times a day), if necessary, the dose can be gradually increased at intervals of 1 week to 5 mg 2 times a day. If the desired clinical results are achieved and long-term treatment is necessary, the dose can be reduced to 1.25 mg 1-2 times a day (3 drops of a 1% solution 1 time a day). IV - 5 mg 2 times a day. The use of a daily dose exceeding 30 mg is not recommended. In pediatric practice, it is prescribed taking into account body weight.
Special instructions: With long-term use, it is necessary to monitor renal function. Prohibited for use in athletes (related to doping).
Interaction: The effect is enhanced by adrenergic and sympathomimetics, ethanol; weakened by sympatholytics. Cardiac glycosides increase bradycardia and increase the risk of developing AV block and arrhythmia.
THE INSTRUCTIONS ARE NOT A PUBLIC OFFER. IT IS FOR INFORMATIONAL CHARACTER.
Side effects
Motrin: reviews from patients about this product are positive in most situations. Undesirable effects after taking this medicine are rare. Basically, these are reversible disorders that go away over time. The most common adverse reactions include:
- dyspepsia (nausea, increased gas formation, abdominal pain, stomatitis, diarrhea);
- vision problems;
- skin allergies, manifested by rashes and itching;
- dyspnea;
- noise in ears;
- dizziness, migraine, drowsiness;
- increased heart rate;
- swelling;
- excessive sweating and thirst.
Motrin can provoke the development of stomach, gastrointestinal bleeding, and peptic ulcers in patients. Therefore, it should be used with caution, especially for older people.
Contraindications
The drug is not allowed to be used if the patient has bronchial asthma, recurrent polyposis of the paranasal sinuses or nose, or with increased individual sensitivity to naproxen, acetylsalicylic acid and other NSAID drugs. The use of the medication during coronary artery bypass surgery is also unacceptable.
Treatment with Motrin is prohibited in patients with erosive lesions or gastric and duodenal ulcers in the acute stage. Its use is not recommended in the presence of renal failure, cerebral and other bleeding, hyperkalienemia, and suppression of hematopoietic function.
The drug is prohibited for use in pregnant women and during lactation, as well as in children under 12 years of age.
Using minimal doses of the drug in a minimal amount of time will help reduce the risk of adverse reactions from the digestive tract. For children 12-16 years old, tablets are prescribed with caution and under the strict supervision of a doctor.
Special information
Do not exceed the permissible dosage of the drug specified in the instructions. Motrin is prescribed with caution to people suffering from pathologies of the kidneys and liver (for example, with renal and liver failure). If after using it the fever and pain are not eliminated, you should definitely consult a specialist.
You should not take this medicine on your own in combination with other painkillers and anti-inflammatory medications (unless prescribed by your doctor). Before surgery and laboratory analysis to determine 17-corticosteroids, Motrin should be discontinued for 48 hours.
Elderly patients are prescribed the lowest effective doses of the drug. The medication affects fertility and should not be used by women who are planning to become pregnant in the near future.
Midodrine
Name: Midodrine Pharmacological action: In terms of chemical structure and pharmacological properties, midodrine is close to adrenaline-like sympathomimetic substances. It has a vasoconstrictor and pressor (increasing blood pressure) effect. Like norepinephrine and mesatone, it stimulates mainly alpha-adrenergic receptors, with little effect on beta-adrenergic receptors; does not have a significant effect on heart rate, contractility of the myocardium (heart muscle), as well as on the bronchial muscles. The vasoconstrictor effect develops more slowly and more evenly than with the use of norepinephrine and mesatone.
Indications for use: Midodrine is used for various types of hypotension (low blood pressure): for orthostatic hypotension (a drop in blood pressure when moving from a horizontal to a vertical position) caused by a violation of the tone of the sympathetic nervous system, for idiopathic (of unclear origin) orthostatic hypotension, secondary hypotension associated with infectious diseases, injuries, and the use of medications.
Directions for use: Midodrine is administered orally and intravenously. Orally, 1 tablet containing 2.5 mg is usually prescribed 2 (less often 3) times a day or 7 drops of a 1% solution 2 times a day. When a clinical effect is achieved and for long-term therapy, 2 tablets (1.25 mg) are prescribed 2 times a day or 3 drops of a \% solution 2 times a day. In some cases, 2 tablets (5 mg each) are first prescribed 2 times a day. If necessary, the contents of 1 ampoule (5 mg) are administered intravenously 2 times a day.
Side effects: Treatment with midodrine must be carried out under the control of blood pressure and other hemodynamic parameters. If the dose is exceeded or individual hypersensitivity is possible, a hypertensive reaction (a rise in blood pressure above normal), bradycardia (rare pulse), increased sweating, pilomotor reaction (“goose bumps”), and disturbances (delayed or increased frequency) of urination are possible.
Contraindications: The drug is contraindicated in hypertension (high blood pressure), pheochromocytoma (adrenal tumors), spastic and obliterating diseases of peripheral vessels (diseases of blood vessels with narrowing of their lumen due to spasm or atherosclerotic deposits), thyrotoxicosis (thyroid disease), adenoma (benign tumor) prostate gland, angle-closure glaucoma (increased intraocular pressure). Caution should be exercised when treating patients with heart failure and arrhythmia, impaired renal function. Midodrine should not be prescribed during pregnancy.
Release form: Tablets containing 0.0025 g (2.5 mg) of midodrine, in a package of 20 or 50 pieces; 1% solution in bottles of 10; 20 or 25 ml; 0.25% solution in ampoules of 2 ml (5 mg per ampoule) in a package of 5 ampoules.
Storage conditions: List B. Protected from light.
Synonyms: Gutron, Alfamin, Hypertane, Midamin.
Attention! The description of the drug " Midodrine " on this page is a simplified and expanded version of the official instructions for use. Before purchasing or using the drug, you should consult your doctor and read the instructions approved by the manufacturer. Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
