Teraflex Hondrocream forte cream 50g Nizhpharm/Russia

Effect on the body

Tissue repair stimulator.

Pharmacokinetics

Glucosamine

Absorption. The bioavailability of glucosamine when taken orally is 25% (the “first pass” effect through the liver).

Metabolism. After absorption of an oral dose, radiolabeled glucosamine is initially detected in the plasma and later penetrates into tissues. The highest concentrations are found in the liver, kidneys and articular cartilage. About 30% of the dose taken persists for a long time in the tissues of bones and muscles.

Elimination. It is excreted primarily by the kidneys unchanged; partly through the intestines. The half-life of the drug is 68 hours.

Chondroitin sulfate

Absorption. When chondroitin sulfate is taken orally in a single dose of 0.8 g (or 2 times a day 0.4 g), the plasma concentration increases over 24 hours. The absolute bioavailability is 12%.

Metabolism. Metabolized by desulfurization.

Elimination. Excreted by the kidneys. Half-life 310 min.

TERAFFLEX chondroCREAM FORTE reviews

TERAFLEX chondrocream forte is a remedy for osteoarthritis.

The longer you live, the more surprised you are at our gullibility and naivety. This love for fairy tales and the eternal expectation of a miracle has probably remained with us since childhood. The main thing is that sometimes we ourselves understand that we are being deceived, and yet we “buy it.” One of the greats said that absolutely anything can be suggested to a person. And the unforgettable Ostap Bender spoke out directly: “More cynicism, people like it.”

Yesterday I saw an advertisement for Teraflex cream on TV and couldn’t resist writing a review. The cream itself was developed by the German company Bayer, but it is produced in Russia by Nizhpharm. The advertisement talks very emotionally and colorfully about this miraculous drug, and after they showed an old man who could not straighten up, but after a single use of the cream started dancing, I just wanted to jump up from the couch and run to the pharmacy after him.

When I started laughing, my wife even got offended at me, saying that it means it’s helping since it’s advertised. This is our naivety. Without any embarrassment, they tell you that the active substances of the drug penetrate deep into the tissues and not only relieve inflammation and stiffness, but also restore cartilage. Here's how. RESTORING!

And many people don’t think that a person is not a scalapendra; he cannot restore or grow anything again. In addition, our skin protects us from the penetration of any nasty things into the tissues. And no active cream additives can reach the joint. And if this were not so, then our skin would absorb, like a sponge, all the infection, all the aggressive substances that we sometimes encounter.

Any cream, be it Teraflex, Dolgit, Capsicam, Finalgon or another, has only a local warming and mild analgesic effect. Nothing else. But at the same time, they are not cheap. The same Teraflex in different pharmacies costs from 450 to 550 rubles. It's not a penny for you.

It is clear that when a person has something in pain, and the joint pain is very severe, he clings to any straw. But you still need to turn on your head. No one is immune from osteochondrosis, arthrosis, arthritis, rheumatism and other ailments. Not at any age. Therefore, it is advisable to monitor your health before problems begin. But this is true, by the way. Most of us don't.

I had glenohumeral periarthritis about a year and a half ago. The pain is hellish, you can’t sleep at night because you can’t rest your arm without it hurting. It was impossible to lift it above the shoulder. And most importantly, I don’t know why this suddenly happened. It seems like I’m not too old yet, and I go to the gym all the time. And here - on you.

No matter what I tried, nothing helped. He even did the vaunted blockades from a series of injections. It's all useless. I surfed the Internet, found fellow sufferers, and one of them said that he was cured by Bubnovsky’s system.

I found several videos of how Bubnovsky worked on one patient’s shoulder through pain. The video, I must say, is not for the faint of heart, because the arm needs to be moved up to its full amplitude, and the pain is hellish, people were just screaming.

But nevertheless, I started trying this method. It was something. He stretched his hand up and rolled on it on the floor. Tears flowed from pain. But each time the amplitude became greater, and the pain subsided. The process is long. I studied for two months. And yet he achieved his goal. Although painful sensations are still felt, the arm can already rotate freely. Many thanks to Bubnovsky.

By the way, I found an interview with him where he says that no creams or injections will help you. Movement is needed, albeit through pain, but so that blood flows to the joints. This is the only way to get rid of these problems. Joint diseases are the scourge of modern man. We move very little, sit for hours in the office at the computer, no physical activity. And the body must work, be in motion.

Every day I tell myself: “That’s it, tomorrow I’ll start living differently. Exercise in the morning, walk in the afternoon, gym in the afternoon.” But tomorrow comes, current affairs must be resolved, new problems arise and the promise to oneself to start a new life is postponed until the day after tomorrow. And so on.

By the way, I told my colleagues how to get rid of joint problems, and it also helped some. Although we tried different creams before.

The only external drug that once helped me against radiculitis was a penny turpentine ointment. It warms up no worse than Finalgon and soothes pain.

So, saving drowning people is the work of the drowning people themselves.

Clinical pharmacology

Stimulates the regeneration of cartilage tissue. Glucosamine and chondroitin sulfate take part in the synthesis of connective tissue, helping to prevent cartilage destruction and stimulate tissue regeneration. Administration of exogenous glucosamine enhances the production of cartilage matrix and provides nonspecific protection against chemical damage to cartilage. Another possible effect of glucosamine is the protection of damaged cartilage from metabolic destruction caused by nonsteroidal anti-inflammatory drugs (NSAIDs) and glucocorticosteroids (GCs), as well as its own moderate anti-inflammatory effect.

Chondroitin sulfate serves as an additional substrate for the formation of a healthy cartilage matrix. Stimulates the formation of hyaluronon, the synthesis of proteoglycans and type II collagen, and also protects hyaluronon from enzymatic breakdown (by suppressing the activity of hyaluronidase); maintains the viscosity of synovial fluid, stimulates cartilage repair mechanisms and inhibits the activity of those enzymes that break down cartilage (elastase, hyaluronidase). In the treatment of osteoarthritis, it relieves the symptoms of the disease and reduces the need for NSAIDs.

Compound

Release form and dosage

Teraflex is available in gelatin-coated capsules. Each capsule contains crystals in the form of a white powder, sometimes with small inclusions of other shades. The drug goes on sale packaged in bottles made of dense polyethylene. The bottle can contain from 30 to 200 capsules.

Typically take one capsule three times a day, regardless of meals. After a 3-week period, the dose is reduced to two capsules per day. Capsules should be taken with a sufficient amount of water. The duration of the course is determined by the doctor, most often it ranges from three months to six months.

Pharmacodynamics

The drug Theraflex® Chondrocream Forte has a combined effect: it slows down the progression of osteoarthrosis and osteochondrosis, has an analgesic effect, helps to increase the range of motion of the joints (in the area where the cream is applied), has an anti-inflammatory effect, and reduces swelling of the joints. Thanks to the optimal combination of cream components, there is a mutual enhancement of their analgesic and anti-inflammatory effects.

Chondroitin sulfate

- high molecular weight mucopolysaccharide, which is a natural component of cartilage tissue. Chondroitin sulfate improves phosphorus-calcium metabolism in cartilage tissue, inhibits enzymes that cause damage to cartilage tissue, inhibits the processes of degeneration (destruction) of cartilage tissue, stimulates the synthesis of glycosaminoglycans, promotes the regeneration (restoration) of cartilaginous surfaces of joints, accelerates their repair processes, and prevents the collapse of connective tissue . This leads to decreased pain and increased mobility of the affected joints.

Meloxicam

- NSAIDs - have anti-inflammatory, analgesic effects. Meloxicam selectively inhibits COX-2, disrupts the metabolism of arachidonic acid, and reduces the amount of PGs (mediators of pain and inflammation) at the site of inflammation. Meloxicam is a chondroneutral drug, does not have a negative effect on cartilage tissue, and does not affect the synthesis of proteoglycan by chondrocytes of articular cartilage.

special instructions

The drug should be applied only to intact skin, avoiding contact with open wounds. The drug should not come into contact with the eyes and mucous membranes.

You should consult your doctor before combining Theraflex® Hondrocream Forte with other NSAIDs, as well as if you need to use the drug for more than 2 weeks.

Influence on the ability to drive vehicles and operate machinery.

The drug does not cause sedation, psychomotor impairment and does not affect the patient’s ability to engage in potentially hazardous activities that require increased attention and speed of mental and motor reactions.

Contraindications

Before you start taking it, it is important to familiarize yourself with the contraindications, which include:

• pregnancy and breastfeeding;

• serious problems with the liver and kidneys;

• bronchial asthma, nasal polyposis, diseases of the paranasal sinuses;

• hemophilia, hyperkalemia and hemorrhagic diathesis.

It is also necessary to take into account individual intolerance to the components of the drug. Persons with heart failure, arterial hypertension, gastritis, enteritis and other diseases can use Teraflex only after consulting a specialist and additional research. It is worth remembering that the drug should not be taken by persons under 15 years of age. Theraflex Advance is contraindicated under 18 years of age.

Special Recommendations

The use of Theraflex may have side effects. If the patient feels that the condition has not improved after using this drug, the drug should be discontinued. After discontinuation of the drug, the side effects disappear.

Theraflex and chronic diseases

Diabetics should take Theraflex with caution. If your doctor has given you permission to use Theraflex, you should always keep your glucose levels under close monitoring. Patients with heart failure, bronchial asthma and kidney problems should be wary of taking this drug and, at the first sign of edema, stop taking it and consult a specialist for discontinuation.

Teraflex and alcohol

Ethyl alcohol increases blood flow in the kidneys, so the active substance will be excreted at an accelerated pace, without having time to have a therapeutic effect.

It is strongly recommended to refrain from drinking alcohol during treatment with the drug. People who have ulcers and erosions in the digestive tract should be especially attentive to this warning.