Vinpocetine forte Canon

Indications and contraindications for Vinpocetine therapy

The instructions contain the following recommendations for the use of the drug:

• chronic, acute circulatory failure in the brain;
• encephalopathy arising from trauma;
• vascular damage to the brain with memory impairment, cephalalgia, dizziness;
• VSD during menopause;
• decreased hearing acuity of toxic, vascular etiology;
• non-inflammatory diseases of the inner ear, etc.

Vinpocetine is contraindicated in patients:

• after acute hemorrhagic stroke;
• with ischemic heart disease, arrhythmia;
• intolerance to the component composition;
• underage.

During therapeutic procedures, Vinpocetine in some cases provokes adverse reactions. The main symptoms are presented:

• increased heart rate, unstable blood pressure;
• changes in ECG, hot flashes;
• extraordinary contractions of the heart muscle;
• attacks of cephalgia with dizziness, insomnia;
• heartburn, nausea, dry oral mucosa;
• allergies with redness, obsessive itching, dermatological rash.

Side effects of the drug are determined by the active work of the sweat glands and a state of general weakness. The occurrence of unusual symptoms requires visiting a doctor and changing the drug.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

A drug that enhances cerebral blood circulation and metabolism. Suppresses the activity of phosphodiesterase , causing the accumulation of cAMP in tissues. Demonstrates a vasodilating effect mainly on the blood vessels of the brain, which is due to the antispasmodic myotropic effect. Systemic blood pressure decreases slightly.

Stimulates blood supply to brain tissue, weakens platelet aggregation, regulates the rheological properties of blood. Improves the resistance to hypoxia of brain cells, stimulating the transfer of oxygen to tissues by reducing the tropism of red blood cells to it, activating the metabolism and absorption of glucose. Increases the concentration of catecholamines in brain cells.

Pharmacokinetics

When taken orally, it is quickly absorbed from the intestines. The highest concentration in the blood is reached after about 1 hour. The half-life reaches 5 hours.

Methods of therapy and dosage from the instructions for Vinpocetine

Tablets for oral administration are prescribed at 5-10 mg, up to 3 times a day. The therapeutic regimen depends on the type of current disease and the severity of the clinical picture.

In an injection solution, the drug is administered intravenously, the maximum single dose does not exceed 20 mg. Injections are used in acute conditions; if therapy in the first days did not cause unusual reactions in the body, then the initial volume is increased for 3-4 days to 1 mg per kilogram of weight. The duration of treatment is 2 weeks.

Accidental increase in the dosage recommended by the instructions provokes the appearance of side effects in the form of allergies, heart rhythm disturbances, sleep problems, headaches and dizziness. To suppress clinical manifestations, the patient's stomach is washed and one of the available sorbents is given: Smecta, activated carbon (1 tablet for every 10 kg of weight). Subsequently, symptomatic therapy is carried out.

Compound

Depending on the manufacturer, 1 Vinpocetine tablet may contain 5 or 10 mg of the active ingredient Vinpocetine .
Additional substances: potato starch, colloidal silicon dioxide, lactose, magnesium stearate. 1 ml of concentrated solution for infusion contains 5 mg of vinpocetine . Additional substances: hydrochloric acid, propylene glycol, sodium disulfite, sorbitol, disodium edetate, sodium sulfite, citric acid, water.

Interaction

No interaction was detected when used simultaneously with Clopamide , β-blockers, Hydrochlorothiazide , Glibenclamide , Acenocoumarol , Digoxin , imipramine .

In some cases, combined use with methyldopa , from which the drug sometimes causes a hypotensive effect. This treatment requires regular monitoring of blood pressure.

There is no data confirming drug interactions with centrally acting drugs, antiarrhythmics and anticoagulants, so caution is recommended during such simultaneous use.

The drug increases the risk of hemorrhagic complications during simultaneous heparin therapy.

Vinpocetine price, where to buy

The price of Vinpocetine tablets in Russia is 50 - 100 rubles depending on the manufacturer, and the price of Vinpocetine Forte 10 mg No. 30 is about 90 rubles.

The average price of such tablets in Ukraine in the above release form is about 30 hryvnia.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Vinpocetine tablets 5 mg 50 pcs. Izvarino Pharma LLC
  98 rub. order
• Vinpocetine Welfarm tablets 10 mg 30 pcs Welfarm LLC

  148 RUR order

• Vinpocetine concentrate for preparation. solution d/inf 5 mg/ml amp. 2ml No. 10Ozon LLC

  RUB 202 order

• Vinpocetine-AKOS tablets 5mg 50 pcs. JSC Sintez

  83 RUR order

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• Vinpocetine tablets 5 mg 50 pcs. Pharmproekt JSC

  53 RUR order

Pharmacy Dialogue

• Vinpocetine Forte-AKOS (tab. 10 mg No. 30) Sintez (Kurgan) OJSC

  93 RUR order

• Vinpocetine-OBL (5 mg tablet No. 50) Obolenskoe pharmaceutical company.

  101 rub. order

• Vinpocetine (5 mg tablet No. 50)Gedeon-Richter

  112 rub. order

• Vinpocetine (5 mg tablet No. 50) Pharmproject CJSC

  56 RUR order

• Vinpocetine tablets 5mg No. 50Update PFK JSC

  93 RUR order

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Pharmacy24

• Vinpocetine-Darnitsa 0.5% 2 ml No. 10 solution for infusion PrAT" Pharmaceutical company "Darnitsa", Ukraine
  26 UAH. order
• Vinpocetine 5 mg No. 30 tablets TOV Astrapharm, Ukraine

  30 UAH order

• Vinpocetine-Darnitsa N30 tablets PrAT” Pharmaceutical company “Darnitsa”, Ukraine

  27 UAH order

• Vinpocetine 0.005 g No. 30 tablets PrAT "Lekhim-Kharkiv", Kharkiv, Ukraine

  26 UAH order

PaniPharmacy

• Vinpocetine infusion Vinpocetine solution d/in. 0.5% amp. 2ml No. 10 Ukraine, Darnitsa ChAO

  35 UAH order

• VINPOCETINE ampoule Vinpocetine solution d/in. 0.5% amp. 2ml No. 5 Ukraine, OZ GNTsLS LLC

  14 UAH order

• Vinpocetine tablets Vinpocetine tablets. 5mg No. 30 Ukraine, Astrapharm LLC

  30 UAH order

• Vinpocetine tablets Vinpocetine tablets. 5mg No. 30 Ukraine, OZ GNTsLS LLC

  24 UAH order

• VINPOCETINE ampoule Vinpocetine-LH solution d/in. 5mg/ml 2ml No. 10 Ukraine, Lekhim-Kharkov JSC

  33 UAH order

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special instructions

The drug should be used orally with caution in cases of angina , arrhythmia , unstable blood pressure and reduced vascular tone.

In acute cases, parenteral medication is used until the patient’s condition improves, then switched to oral administration. For chronic disorders, the drug is also taken orally.

In case of cerebral hemorrhagic stroke, intravenous administration of the drug is permitted only after the acute effects have subsided.

Side effects

Side effects are the same for Vinpocetine and other drugs with a similar composition.

• Reactions from the blood circulation: increased heart rate, instability of blood pressure, ECG changes, extrasystole , hot flashes .
• Reactions from nervous activity: dizziness, insomnia , headache .
• Digestive reactions: nausea, dry mouth, heartburn .
• Other reactions: weakness, allergic reactions, increased sweating.

Vinpocetine analogs

Level 4 ATX code matches:
Bravinton

Acefen

Carnicetine

Pyracesin

Nooclerin

Semax

Piracetam

Olatropil

Fezam

Cerebrocurin

Cavinton Forte

Calcium hopantenate

Glutamic acid

Cephabol

Olanzapine

Cerebrolysate

Pramistar

Sidnocarb

Vinpotropil

Glycine Ozone

Analogues of Vinpocetine:

• Cavintazole
• Bravinton
• Vicebrol
• Cavinton
• Neurovin
• Oxopotin