Ascoril
Release form
Pills. White, round, flat tablets with a bevel and a one-sided score.
Compound
Active ingredients : bromhexine hydrochloride (8 mg); guaifenesin (100 mg); salbutamol sulfate (equivalent to salbutamol, 2 mg).
Excipients : calcium hydrogen phosphate; corn starch; methyl parahydroxybenzoate (methylparaben); propyl parahydroxybenzoate (propylparaben); purified talc; colloidal silicon dioxide; magnesium stearate.
Pharmacological group
A drug with mucolytic, expectorant and bronchodilator effects, a combined expectorant
Action
Mucolytic, expectorant, bronchodilator.
Bromhexine is a mucolytic agent that has an expectorant effect. Increases the serous component of bronchial secretions; activates the cilia of the ciliated epithelium, reduces the viscosity of sputum, increases its volume and improves discharge.
Bromhexine - description of the substance
Guaifenesin is a mucolytic agent that reduces the surface tension of the structures of the bronchopulmonary apparatus; stimulates secretory cells of the bronchial mucosa that produce neutral polysaccharides, depolymerizes acidic mucopolysaccharides, reduces the viscosity of sputum, activates the ciliary apparatus of the bronchi, facilitates the removal of sputum and promotes the transition of an unproductive cough to a productive one.
Salbutamol is a bronchodilator that stimulates beta2-adrenergic receptors of the bronchi, blood vessels and myometrium. Prevents or eliminates bronchospasm, reduces resistance in the respiratory tract, increases the vital capacity of the lungs. Causes expansion of the coronary arteries, does not reduce blood pressure.
Indications
As part of combination therapy for acute and chronic bronchopulmonary diseases, accompanied by the formation of a difficult to separate viscous secretion:
- bronchial asthma;
- tracheobronchitis;
- obstructive bronchitis;
- pneumonia;
- emphysema;
- whooping cough;
- pneumoconiosis;
- pulmonary tuberculosis.
Contraindications and restrictions
- Hypersensitivity to the components of the drug;
- tachyarrhythmia, myocarditis;
- heart defects;
- decompensated diabetes mellitus;
- thyrotoxicosis;
- glaucoma;
- liver or kidney failure;
- peptic ulcer of the stomach and duodenum in the acute stage;
- stomach bleeding;
- arterial hypertension;
- pregnancy;
- lactation period;
- children under 6 years of age.
with caution to patients with diabetes mellitus, gastric and duodenal ulcers in remission.
during pregnancy . If treatment with the drug is necessary during lactation, breastfeeding should be discontinued.
Application and dosage
Inside, 3 times a day.
- Adults and children over 12 years old - 1 tablet each;
- children from 6 to 12 years old - 1/2 or 1 tablet;
- Children under 6 years of age are recommended to use Ascoril Expectorant syrup.
Side effect
From the immune system: rarely - hypersensitivity reactions; frequency unknown - anaphylactic reactions, including anaphylactic shock, angioedema and itching.
From the side of the central nervous system: rarely - headache, dizziness, increased nervous excitability, sleep disturbance, drowsiness, tremor, convulsions.
From the cardiovascular system: rarely - rapid heartbeat, collapse.
From the respiratory system, chest and mediastinal organs: rarely - bronchospasm.
From the gastrointestinal tract: rarely - nausea, vomiting, diarrhea, exacerbation of gastric and duodenal ulcers.
From the kidneys and urinary system: rarely - urine may turn pink.
From the skin and subcutaneous tissues: rarely - rash, urticaria; frequency unknown - severe skin adverse reactions (including erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis and acute generalized exanthematous pustulosis associated with the use of ambroxol (ambroxol is a metabolite of bromhexine).
Overdose
Symptoms: increased side effects. Treatment: symptomatic therapy.
special instructions
There have been reports of severe skin reactions such as erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis and acute generalized exanthematous pustulosis associated with the use of ambroxol. Since ambroxol is a metabolite of bromhexine, the risk of anaphylactic and severe skin reactions may also be considered for bromhexine.
If symptoms of a progressive skin reaction occur (sometimes associated with damage to the mucous membranes of the mouth, throat, nose, eyes, genitals), you should immediately stop using the drug Ascoril and consult a doctor.
Guaifenesin turns urine pink.
Drug interactions
- It is not recommended to take alkaline drinks at the same time as the drug.
- Other beta2-adrenergic agonists and theophylline enhance the effect of salbutamol and increase the likelihood of side effects.
- Ascoril is not prescribed simultaneously with drugs containing codeine and other antitussives, because this makes it difficult to clear liquefied sputum.
- Bromhexine, which is part of the drug Ascoril, promotes the penetration of antibiotics (erythromycin, cephalexin, oxytetracycline) into the lung tissue.
- It is not recommended to use Ascoril simultaneously with non-selective beta-adrenergic blockers, such as propranolol.
- Salbutamol, which is part of the drug Ascoril, is not recommended for patients receiving MAO inhibitors.
- Diuretics and corticosteroids enhance the hypokalemic effect of salbutamol.
Storage
Store out of the reach of children at room temperature no higher than 25°C. Shelf life: 2 years.
Production
Glenmark Pharmaceuticals Ltd (India)
Package
10 pieces. in cellular contour packaging. 1, 2 or 5 packages in a cardboard box.
Recipe
Available without a prescription.
Compound
Syrup composition: 10 ml of syrup contains 100 mg of guaifenesin , 4 mg of bromhexine hydrochloride , 2 mg of salbutamol sulfate , 1 mg of menthol .
Excipients:
- purified water;
- sucrose;
- sunset yellow dye;
- black currant flavor;
- pineapple flavor;
- glycerol;
- sorbitol;
- sodium benzoate;
- propylene glycol;
- citric acid monohydrate.
Composition of the medicine in tablets : one tablet contains 100 mg of guaifenesin , 8 mg of bromhexine hydrochloride , 2 mg of salbutamol sulfate .
One tablet also contains the following excipients:
- purified talc;
- corn starch;
- methyl parahydroxybenzoate;
- colloidal silicon dioxide;
- propyl parahydroxybenzoate;
- Magnesium stearate.
Askoril price, where to buy
The price varies depending on the country, and more specifically, the city.
The cost of the drug in Russia starts from 180 rubles.
The price of Ascoril syrup in Ukraine ranges from 130 to 230 UAH. In Kharkov, this medicine can be bought for 140 UAH. You can find out exactly how much the syrup costs at your nearest pharmacy.
The price of Ascoril tablets is approximately 117 – 280 UAH, depending on the pack. In Odessa, Ascoril tablets can be purchased for approximately 120 to 230 UAH.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Ascoril tablets 20 pcs. Glenmark Pharmaceuticals LTD RUB
375 order - Ascoril Expectorant syrup 200mlGlenmark Pharmaceuticals LTD
RUR 494 order
- Ascoril Expectorant syrup 100mlGlenmark Pharmaceuticals LTD
RUB 356 order
- Ascoril tablets 50 pcs. Glenmark Pharmaceuticals LTD
RUR 927 order
- Ascoril tablets 10 pcs. Glenmark Pharmaceuticals LTD
RUB 261 order
Pharmacy Dialogue
- Ascoril (tab. No. 20)Glenmark Pharm
RUB 376 order
- Ascoril (tab. No. 50)Glenmark Pharm
903 rub. order
- Ascoril (tab. No. 10)Glenmark Pharm
RUB 242 order
- Ascoril (tab. No. 20)Glenmark Pharm
RUR 414 order
- Ascoril expectorant (syrup 200ml)Glenmark Pharm
480 rub. order
show more
Pharmacy24
- Ascoril No. 50 tablets Glenmark Pharmaceuticals Ltd., India
257 UAH.order - Ascoril expectorant 100 ml syrup Glenmark Pharmaceuticals Ltd, India
131 UAH order
- Ascoril No. 20 tablets Glenmark Pharmaceuticals Ltd., India
106 UAH order
- Ascoril Expectorant 200 ml syrup Glenmark Pharmaceuticals Ltd, India
198 UAH order
PaniPharmacy
- Ascoril liquid Ascoril expectorant syrup 100ml India, Glenmark
142 UAH order
- Ascoril tablets Ascoril tablets No. 50 India, Glenmark
279 UAH. order
- Ascoril liquid Ascoril expectorant syrup 200ml India, Glenmark
228 UAH order
- Ascoril tablets Ascoril tablets No. 20 India, Glenmark
117 UAH. order
show more
Ascoril for children
Many parents ask the question: “For what cough do they give this or that medicine?” As for Ascoril, doctors prescribe it for dry coughs in order to speed up the treatment process.
Also, many people are concerned about whether to take medicine before or after meals. It can be taken regardless of meals.
In general, many recommend giving both tablets and Ascoril syrup to children; reviews of this drug are very positive. Many parents praise this medicine in comparison with other analogues.
Instructions for use for children are as follows:
Ascoril cough syrup:
- up to 6 years, 5 ml 3 times a day;
- from 6 to 12 years – 5-10 ml per day;
- from 12 years old – 10 ml 3 times a day.
Cough tablets:
Children under 6 years of age are not recommended to take this medicine.
- from 6 to 12 years – ½ tablet 3 times a day;
- from 12 years old – 1 tablet 3 times a day.
Reviews for Ascoril
In general, doctors' reviews of Ascoril tablets are positive, but some experts are skeptical about it because of the manufacturer. Reviews about the syrup are no different.
Patients say that the drug helps quickly and without complaints. Many people recommend giving this particular syrup to children; reviews of the tablets among patients are the same. The medicine also attracts patients because of its affordable price.
However, some patients complain of severe side effects ( tremor , dizziness , rapid heartbeat , increased blood pressure).
