Hepilor solution and spray: instructions for use, price and reviews

Compound

Active ingredients: hexetidine , chlorobutanol and choline salicylate .
100 ml of solution contains hexetidine - 0.1 g, choline salicylate - 0.5 g, chlorobutanol hemihydrate - 0.25 g, as well as auxiliary components: ethanol, eucalyptol, sodium saccharin, polysorbate 20, lemon and anise oil, propionic acid, menthol, clean water.

50 ml of spray contains hexetidine - 0.05 g, choline salicylate - 0.25 g, chlorobutanol hemihydrate - 0.125 g, as well as auxiliary components.

Pharmacodynamics and pharmacokinetics

The therapeutic effect is achieved by the complex effect of three active substances at once.

Hexetidine has fungicidal and antimicrobial effects. Affects gram-positive cocci, gram-negative flora, aerobes (bacteriostatic effect) and anaerobes (pronounced bactericidal effect). The chemical structure of hexetidine is close to thiamine, which is required for the growth and development of microorganisms. The death of bacteria is achieved through the replacement of thiamine at a competitive level.

Chlorobutanol has an analgesic effect. The anesthetic is widely used in otorhinolaryngology (nasal drops, rinses) and dental practice (in the form of solution application and spray irrigation).

Choline salicylate has analgesic and anti-inflammatory effects and is actively used in the treatment of oral diseases.

The active components of the drug are retained on the mucous walls, providing gradual release and a long-lasting therapeutic effect.

special instructions

When using the drug, do not swallow and avoid contact with eyes; use caution in patients with liver disease, since the drug contains ethanol.

The drug should be used with caution in patients with epilepsy. The drug may lower the epileptic threshold and cause seizures in children. Use with caution in patients with allergic reactions.

There is a risk of laryngospasm in children due to the presence of levomenthol.

Long-term use is not recommended as it may alter the natural microbial balance of the mouth and throat, where there is a risk of bacterial or fungal spread.

If general clinical signs of a bacterial infection appear, general antibacterial therapy should be provided.

If symptoms persist for more than 5 days and/or body temperature increases, if inflammation increases, drug therapy should be discontinued and treatment tactics should be reconsidered.

Use during pregnancy or breastfeeding. There are no data from human studies on the possibility of hexetidine crossing the placenta and excretion into breast milk, therefore the drug should not be used during pregnancy or breastfeeding.

Children. Use the drug in children over 6 years of age.

The ability to influence reaction speed when driving vehicles or working with other mechanisms. The drug contains ethanol. Drivers are not recommended to drive a vehicle for 30 minutes after using the drug.

Indications for use

Hepilor spray is prescribed for sore throat , pharyngitis , canker sores , gingivitis , stomatitis , tonsillitis (acute and chronic forms), and laryngitis .

The medication is effectively used in the treatment of diseases of the oropharynx of infectious origin.

Instructions for use of Hepilor recommend the drug for hygienic care of the oral cavity after dental procedures.

Side effects

From the immune system: hypersensitivity reactions, including urticaria, angioedema, laryngospasm, bronchospasm;

from the nervous system: ageusia, dysgeusia, change in taste sensations within 48 hours (the sensation of “sweet” can change twice to the sensation of “bitter”).

from the respiratory system, chest and mediastinal organs: cough, shortness of breath, sore throat;

from the digestive system: dry mouth, dysphagia, enlarged salivary glands, pain when swallowing. If the drug is accidentally ingested, gastrointestinal disorders may occur, primarily nausea and vomiting;

on the part of the skin and subcutaneous tissue: allergic contact dermatitis, skin reactions (rashes);

general disorders and condition of the application site: local reactions - reversible change in the color of teeth and tongue; sensitivity of the mucous membrane, namely burning, numbness; irritation (pain, feeling of heat, itching) of the tongue and/or oral mucosa; decreased sensitivity; paresthesia of the mucous membrane; inflammation; bubbles; the occurrence of ulcers on the mucous membrane, swelling at the site of contact, dryness of the mucous membrane of the nose/throat.

If any adverse reactions occur, you should stop using the drug and be sure to consult a doctor.

Instructions for Hepilor (Method and dosage)

The duration of therapy with Hepilor is determined by the attending physician. The medication is used only locally. Avoid getting the solution into your eyes. It is recommended to refrain from drinking and eating for 30 minutes after applying the drug.

Spray Hepilor, instructions for use

The spray is used 4-6 times a day (1 spray per session). The duration of treatment is no more than 5 days.

Solution

Hepilor solution is diluted in warm water: 2 teaspoons (10 ml) per 50 ml of water. Every day you need to do 2-4 rinses. Duration of therapy – 5 days.

The spray and solution should not be swallowed. If body temperature rises and there is no positive dynamics within 5 days, it is recommended to reconsider the treatment regimen (identify the pathogen, clarify the diagnosis).

Hepilor spray 20ml No. 1

Name

Hepilor spray for oral mucosa in bottle. 20ml per pack. No. 1

Description

a clear or slightly opalescent liquid with a specific aromatic odor and alcohol-anise taste, located in a bottle with a pump valve equipped with a sprayer. The drug is removed from the bottle through a sprayer in the form of an aerosol stream.

Main active ingredient

hexetidine, choline salicylate, chlorobutanol hemihydrate

Release form

Spray for the oral mucosa

Dosage

20ml

Pharmacological properties

Pharmacodynamics

The effect of the drug Hepilor is due to the combination of three active components included in its composition - hexetidine, choline salicylate and chlorobutanol. Hexetidine is an antiseptic with bactericidal and bacteriostatic effects, active against pathogenic microorganisms of the oral cavity, such as Streptococcus, Candida albicans, Bacteroides sp., Klebsiella aerobacter, Staphylococcus sp. The antimicrobial activity of hexetidine is based on the oxidation of glucose in the absence of phosphorylation. Choline salicylate is an anti-inflammatory agent. Chlorobutanol belongs to the group of analgesics, but also has anti-inflammatory effects. Chlorobutanol, like choline salicylate, prolongs the effect of hexetidine. This interaction of active substances helps to suppress the growth of pathogenic microorganisms in the oral cavity for a long time: 6 hours after using the drug, suppression of the growth of pathogenic microorganisms is observed in 70%.

Pharmacokinetics

The active substances are fixed on the oral mucosa, from where they are gradually released without having a systemic effect on the patient’s body.

Indications for use

Symptomatic treatment of infectious and inflammatory diseases of the mouth and throat.

Directions for use and doses

Used locally for irrigation of the oral cavity. 1 spray 4–6 times a day (each spray releases approximately 0.5 ml). This medicine is intended for symptomatic treatment and cannot be used for a long time. Special Populations There are no dosing recommendations for elderly patients or patients with impaired renal function. Patients with impaired liver function Use with caution in patients with liver disease, since the drug contains ethanol. Children Hepilor spray should not be used in children under 12 years of age.

Precautionary measures

When using the drug, do not swallow and avoid contact with eyes; use caution in patients with liver disease, since the drug contains ethanol. The drug should be used with caution in patients with epilepsy. The drug may reduce the epileptic threshold and cause seizures in children. Use with caution in patients with a predisposition to allergic reactions, especially in patients allergic to salicylic acid. There is a risk of laryngospasm in children due to the presence of levomenthol. Long-term use is not recommended as it may alter the natural microbial balance of the mouth and throat, where there is a risk of bacterial or fungal spread. If general clinical signs of a bacterial infection appear, general antibacterial therapy should be provided. If symptoms persist for more than 5 days and/or body temperature increases, treatment should be stopped and treatment tactics reconsidered if inflammation increases. Use during pregnancy or lactation: There are no studies in humans on the possibility of hexetidine crossing the placenta and excretion into breast milk, therefore the drug should not be used during pregnancy or lactation. The ability to influence the reaction rate when driving vehicles or operating other mechanisms: The drug contains ethanol. Drivers are not recommended to drive for 30 minutes after using the drug.

Interaction with other drugs

Do not use together with drugs containing antiseptics (there may be interaction with other antiseptic drugs). Hexetidine can be inactivated by alkaline solutions.

Contraindications

Children under 12 years of age, as the drug contains alcohol (danger of swallowing). Hypersensitivity to salicylates (aspirin and its derivatives) or any of the components of Hepilor. Atrophic pharyngitis. Bronchial asthma or any other respiratory diseases associated with hypersensitivity.

Compound

active ingredients: hexetidine, choline salicylate, chlorobutanol hemihydrate; 1 ml of spray contains hexetidine - 1 mg, choline salicylate 80% - 5 mg, chlorobutanol hemihydrate - 2.5 mg; excipients: ethanol (96%), sodium saccharin, polysorbate 20, propionic acid, citric oil, anise oil, menthol (levomenthol), eucalyptol, purified water. Spray for the oral mucosa

Overdose

If a sufficient amount of Hepilor oral spray is absorbed, alcohol intoxication may occur due to the ethyl alcohol content. The concentration of hexetidine contained in Hepilor, oral spray, is not toxic if the drug is used as directed. The occurrence of acute alcohol intoxication is extremely unlikely. If a child swallows a significant dose of the drug, alcohol intoxication may occur due to the ethyl alcohol content. There are no cases of excessive use of hexetidine, which led to hypersensitivity reactions. Treatment: symptomatic. If a child swallows the contents of the bottle, consult a doctor immediately. It is necessary to consider the possibility of performing gastric lavage within 2 hours after ingestion and direct efforts to eliminate signs of alcohol intoxication.

Side effect

From the immune system: hypersensitivity reactions, including urticaria, angioedema, laryngospasm, bronchospasm. From the nervous system: ageusia, dysgeusia, change in taste sensations within 48 hours (the sensation of “sweet” can change twice to the sensation of “bitter”). From the respiratory system, chest and mediastinal organs: cough, shortness of breath. From the digestive system: dry mouth, dysphagia, enlarged salivary glands, pain when swallowing. If the drug is accidentally ingested, gastrointestinal disorders may occur, primarily nausea and vomiting. From the skin and subcutaneous tissue: allergic contact dermatitis, skin reactions (rash). General disorders and disorders at the injection site: local reactions - reversible change in the color of teeth and tongue; sensitivity of the mucous membrane, namely burning, numbness; irritation (pain, feeling of heat, itching) of the tongue and/or oral mucosa; decreased sensitivity; paresthesia of the mucous membrane; inflammation; bubbles; the appearance of ulcers on the mucous membrane, a sore throat; swelling at the site of contact, dryness of the mucous membrane of the nose/throat.

Storage conditions

Store out of the reach of children at a temperature not exceeding 25 °C. Do not freeze.

Buy Hepilor spray 20ml No. 1 in the pharmacy

Price for Hepilor spray 20ml No. 1

Instructions for use for Hepilor spray 20ml No. 1

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Note!

Description of the drug Hepilor spray for mouth. floor. fl. 50ml on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.

Hepilor price, where to buy

The price of Hepilor spray is 275 rubles. The solution costs about 240 rubles.

Online pharmacies in RussiaRussia
Online pharmacies in UkraineUkraine
Online pharmacies in KazakhstanKazakhstan

LuxPharma* special offer

Hepilor oral spray 50ml
RUB 1,290 order

Pharmacy24

Hepilor 20 ml spray PAT "Farmak", Ukraine
60 UAH. order
Hepilor 100 ml solution PAT "Farmak", Ukraine
69 UAH order
Hepilor 50 ml spray PAT "Farmak", Ukraine
77 UAH order

PaniPharmacy

Hepilor liquid Hepilor spray for half mouth 50ml Ukraine, Farmak OJSC
90 UAH order
Hepilor liquid Hepilor solution for rinsing. mouths cavities fl. 100ml Ukraine, Farmak OJSC
74 UAH order
Hepilor liquid Hepilor spray for half mouth 20ml Ukraine, Farmak OJSC
72 UAH order

Overdose

If a sufficient amount of Hepilor oral solution or spray is absorbed, alcohol intoxication may occur due to the ethyl alcohol content.

The concentration of hexetidine contained in Hepilor oral solution or spray is not toxic if the drug is used as directed.

The occurrence of acute alcohol intoxication is extremely unlikely. If a child swallows a significant dose of the drug, alcohol intoxication may occur due to the ethyl alcohol content.

There are no cases of excessive use of hexetidine, which led to hypersensitivity reactions.

Treatment: symptomatic. If a child swallows the contents of the bottle, consult a doctor immediately. It is necessary to consider the possibility of performing gastric lavage within 2 hours after ingestion and take measures to eliminate signs of alcohol intoxication.