Sodium tetraborate
Registration number: LP-000641
Trade name: Sodium tetraborate.
Chemical name: Sodium tetraborate decahydrate.
Dosage form: Solution for local and external use.
Composition: Active substance:
- Sodium tetraborate decahydrate - 20.0 g
Excipients:
- Glycerol (glycerin) - 72.8 g
- Purified water - 7.2 g
Description: Colorless transparent or slightly opalescent viscous liquid.
Pharmacotherapeutic group: Antiseptic.
ATX code: D08AD
Pharmacological action: Has bacteriostatic activity. Removes the mycelium of the fungus from the mucous membranes, disrupts the process of attachment of the fungus to the mucous membranes and, due to this, inhibits its reproduction (it is not an antifungal drug, because it does not have a fungicidal or fungistatic effect).
Pharmacokinetics: Systemic absorption for local and external use is low; absorbed in the gastrointestinal tract with partial swallowing (by lubricating the mucous membrane of the oral cavity, pharynx), and can be absorbed through damaged skin. Deposited in bone tissue and liver. It is excreted unchanged by the kidneys and through the intestines within one week.
Indications for use: Candidiasis of the oral mucosa, pharynx, upper respiratory tract, external genitalia. Diaper rash, bedsores.
Contraindications:
Hypersensitivity to the drug; violation of the integrity of the skin (during skin treatment). Pregnancy, lactation period.
Directions for use and dosage: Locally and externally. Candidiasis of the mucous membrane of the oral cavity, pharynx, upper respiratory tract: lubricate the affected areas of the mucous membrane 2 - 3 times a day. The course of treatment is 3 - 7 days. The frequency of use and duration of treatment in children must be agreed with a doctor. Vaginal candidiasis (thrush): before using the drug, it is necessary to douche with boiled water or infusion of chamomile flowers. Then moisten a cotton swab in a sodium tetraborate solution and insert it into the vagina for 20 - 30 minutes. For minor discharge and itching, the drug is used once a day (at night), and for heavy discharge, 2 times a day (morning and night). The course of treatment is 5 - 7 days. Diaper rash, bedsores: lubricate the affected areas of the skin 2 - 3 times a day. The duration of treatment depends on the degree and area of the lesion.
Side effect: Hyperemia and burning sensation at the site of application or administration of the drug.
Overdose: Cases of overdose have not been registered to date.
Interaction with other drugs: Not known.
Special instructions: When monotherapy for vaginal candidiasis, in order to increase efficiency, it is necessary that treatment procedures be carried out by medical personnel many times; otherwise, the mycelium of the fungus may linger in the crypts of the vaginal mucosa, which will lead to relapse of the disease.
Release form: Solution for local and external use 20%. 30 g in orange glass bottles. Each bottle, along with instructions for use, is placed in a cardboard box. It is allowed to place bottles with an equal number of instructions for use in a group package.
Storage conditions: In a place protected from light at a temperature not exceeding 25 ° C. Keep out of the reach of children.
Shelf life: 3 years. Do not use after the expiration date.
Conditions for dispensing from pharmacies: Without a prescription.
Sodium Tetraborate in glycerin solution for external and local use 20% fl 30g
Compound
active substance: Sodium tetraborate decahydrate - 20 g Excipient: Glycerin (glycerol) - 80 g
Pharmacokinetics
Systemic absorption for local and external use is low; absorbed in the gastrointestinal tract with partial swallowing (by lubricating the mucous membrane of the oral cavity, pharynx), and can be absorbed through damaged skin. Deposited in bone tissue and liver. It is excreted unchanged by the kidneys and through the intestines within one week.
Indications for use
Candidiasis lesions of the mucous membrane of the oral cavity, pharynx, genital organs; diaper rash, bedsores. If necessary, please consult your doctor before using the medicine.
Contraindications
Hypersensitivity to the components of the drug, pregnancy, lactation, childhood. Violation of the integrity of the mucous membrane and skin.
Directions for use and doses
Locally and externally. Age category of patients: adults. Externally - to lubricate the skin 2-3 times a day. Locally - to lubricate the oral mucosa. Lubricate the affected areas of the oral mucosa 2-3 times a day. The course of treatment is 3-7 days. When treating vaginal candidiasis (thrush), before using the drug, it is necessary to douche with boiled water or chamomile solution, after which a tampon soaked in the drug is inserted into the vagina for 20-30 minutes. The frequency of use and course of treatment depend on the severity of the disease. For minor discharge and itching, the drug is used once a day, preferably at night, and for heavy discharge, the drug is used 2 times a day (morning and evening) for 5-7 days. If there is no improvement after treatment or new symptoms appear, you should consult your doctor. Use the drug only according to the method of use and in the doses indicated in the instructions. If necessary, please consult your doctor before using the medicine.
Storage conditions
In a place protected from light, at a temperature not exceeding 30 °C. Keep out of the reach of children.
Best before date
3 years. Do not use after the expiration date stated on the packaging.
special instructions
The condition for effectiveness in monotherapy of vaginal candidiasis is the need for medical procedures to be carried out by medical personnel and multiple treatments; otherwise, fungal cells may linger in the vaginal crypts and lead to relapse. Read the instructions carefully before you start using the drug. Save the instructions, you may need them again. If you have any questions, consult your doctor. The medicine you are using is intended for you personally and should not be given to others as it may cause harm to them even if they have the same symptoms as you.
Description
Colorless, viscous liquid.
Conditions for dispensing from pharmacies
On prescription
Dosage form
solution for local and external use
Use in children
Contraindicated.
Manufacturer and organization accepting consumer complaints
IVANOVSKAYA Pharmaceutical Factory, JSC
Pharmacodynamics
Antiseptic. Has bacteriostatic activity. Effective against candidiasis. Removes the mycelium of the fungus from the mucous membranes, disrupts the process of attachment of the fungus to the mucous membranes and inhibits its reproduction (it is not an antifungal drug, because it does not have a fungicidal or fungistatic effect).
Side effects
Allergic reactions; hyperemia, burning sensation at the site of application of the drug. If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.
Use during pregnancy and breastfeeding
The use of the drug during pregnancy and lactation is contraindicated.
Interaction
No information available.
Overdose
Symptoms after accidental ingestion (lethal dose for adults - 10-20 g, toxic concentration in the blood - 40 mg/l, lethal - 50 mg/l): abdominal pain, vomiting, loss of appetite, diarrhea, dehydration, weakness, confusion consciousness, dermatitis, menstrual irregularities, anemia, twitching of the muscles of the face and limbs, alopecia, dysfunction of the heart, liver and kidneys. Treatment: gastric lavage, forced diuresis, in case of severe poisoning - hemodialysis, IM - riboflavin mononucleotide 10 mg/day, correction of water-electrolyte balance and acidosis: IV infusion of sodium bicarbonate solution, plasma-substituting solutions, sodium chloride and dextrose solution . For abdominal pain - subcutaneous injection of 1 ml of 0.1% atropine solution, 1 ml of 0.2% platyphylline solution, 1 ml of 1% promedol solution, intravenous dextrose-procaine mixture (50 ml of 2% procaine solution and 500 ml of 5% dextrose solution). Maintaining the functions of the cardiovascular system. There is no information about the symptoms of overdose with local and external use of the drug.
Impact on the ability to drive vehicles and operate machinery
No information available.
Contraindications for use
Contraindications to the use of the solution include:
- Pregnancy and breastfeeding period;
- Age up to 10 years (in exceptional cases, treatment of stomatitis in children is carried out under the supervision of a doctor);
- Hypersensitivity to one of the components of the drug;
- Violation of the integrity of the skin or mucous membranes.
The solution should not be taken orally. Partial ingestion is acceptable when treating the oral cavity during the treatment of stomatitis.
Before the first use, you must make sure that there is no allergic reaction to the drug. To do this, a small amount of sodium tetraborate must be applied to the area of skin or mucous membrane that is to be treated. If no discomfort appears within 2 hours, the solution can be used for treatment.
Borax mineral: history, composition, description and varieties
Borax is the sodium salt of boric acid. Its empirical formula is Na₂B₄O₇. The substance has a crystalline structure. It was first widely used in Central Asia, where it acquired the name “tankal”. But sodium tetraborate owes its modern name to the Persians, who nicknamed it “burah,” which meant “a mixture of flux and water.” The ancient Egyptians widely used borax during mummification. In medieval Europe, borax was used to clean metal surfaces: dishes and other household items.
By adding borax to the cat litter, it is possible to reduce the intensity of the odor emanating from it several times Source Decorobot.ru
Precautionary measures
- Instruct personnel about the risks associated with the product, the precautions to be taken and the measures to be taken in the event of an accident.
- Don't eat or drink in the workplace.
- Limit the amount of products in workshops (shops) to the minimum requirements.
- Avoid dust accumulation. Keep premises and work areas immaculately clean.
- Avoid breathing dust or aerosols.
- Provide general ventilation of the premises.
- Avoid contact of the product with skin and eyes. Provide personnel with protective clothing, gloves and safety glasses. These items must be kept in good condition and cleaned after each use.
- It is prohibited to work with tanks containing disodium tetraborate without following safety precautions.
- In case of accidental leakage or spillage, remove the product using a commercial vacuum cleaner. If the spill is large, evacuate personnel.
- Store waste in specially designed containers. Dispose of waste in accordance with approved regulations.
- Avoid exposure of disodium tetraborate to people with chronic respiratory conditions or skin conditions of exposed parts.
