The best way to treat nits and lice is to use shampoos. This method is effective, easy to use, and in most cases has a high degree of safety compared to other means. Shampoos are especially good for young patients, since they are less likely than lotions and emulsions to lead to the development of an allergic reaction and do not cause skin irritation. Pedilin shampoo can be used from the age of two. The drug has only one contraindication - hypersensitivity to any substance in the composition. So, a description of the product for the treatment of pediculosis, instructions for using Pedilin shampoo and composition - information in the review.
Pharmacodynamics and pharmacokinetics
The main active ingredient is malathion . Pedilin belongs to the group of insecticides of organophosphorus origin and has an anti-pediculosis effect .
The drug easily penetrates the chitinous cover, reaches high concentrations in the insect’s body, and irreversibly inhibits the enzyme cholinesterase , forming a covalent bond with it. Lice and nits die as a result of self-poisoning with acetylcholine .
Pedilin 100 ml shampoo.
Approved by the Order of the Chairman of the Pharmaceutical Control Committee of the Ministry of Health of the Republic of Kazakhstan dated "_05_"_09______ 2008_ No. 211__ Instructions for the medical use of the drug PEDILIN Trade name Pedilin International nonproprietary name Permethrin Dosage form Shampoo 100 ml Composition 100 g of shampoo contains the active substance - permethrin 1 g, excipients: imidomerea, citric acid, alkyl sulfate ether, sodium lauryl sulfate, diethanolamidic acid cocoate, propylene glycol, chamomile fragrance, purified water. Description Thick pearl-white liquid with a strong odor Pharmacotherapeutic group Preparations for the destruction of ectoparasites. Pyrethrins. ATC code P03AC04 Pharmacological properties Permethrin belongs to the group of pyrethroid insecticides - analogues of the natural insecticide pyrethrin, found in the flower extract of some types of tansy. Permethrin quickly penetrates the nervous system of insects and is a nerve and contact poison that is very effective against lice. In addition to lice, it also destroys nits. Permethrin acts directly on the membranes of nerve cells in insects. The mechanism of action is to inhibit the repolarization process by blocking sodium channels in the membrane of the nerve cell, which regulates the polarization of the membrane, resulting in paralysis and death of the insect. Indications for use - treatment and prevention of pediculosis Method of administration and dosage Moisten the scalp or scalp of the human body (in the presence of pubic lice) generously with water and intensively lather with pediculicidal shampoo until a stable foam is formed. 10 minutes after applying the product, rinse it off with running water from the treated parts of the body, then wash them as usual. Rinse your scalp with a 4.5% aqueous solution of table vinegar (dilute 9% table vinegar with water in a 1:1 ratio), comb with a fine comb to remove dead insects. The consumption rate of pediculicidal shampoo is 10–30 ml, depending on the degree of insect infestation, hair length and thickness. The treatment must be repeated after 7–10 days, but no more than twice a month. Side effects Rarely: allergic rash, irritation Contraindications - hypersensitivity to the components of the drug - children under 5 years of age - pregnancy and lactation Drug interactions Not known Special instructions Before treating hair, to avoid getting shampoo on the mucous membranes of the eyes and nasopharynx, you should tie it around head (below the hair) a cotton scarf rolled into a rope. If the product accidentally gets into your eyes, rinse them thoroughly with a stream of warm water. If you use contact lenses, they should be removed before using pediculicidal shampoo. Effect of the drug on the ability to drive a vehicle or operate potentially dangerous machinery: No effect Overdose Symptoms: when applied topically, overdose is not possible. Treatment: If swallowed, do not induce vomiting. Treatment is symptomatic. Release form and packaging 100 ml of shampoo in a plastic bottle. 1 bottle in a cardboard box along with instructions for use. Storage conditions Store in a place protected from light, at a temperature not exceeding +25°C. Keep out of the reach of children! Shelf life: 2 years Do not use after the expiration date indicated on the package. Conditions for dispensing from pharmacies Without a prescription Manufacturer KRKA, d.d. Novo mesto, Slovenia
Overdose
With prolonged inhalation of the drug, prolonged skin contact, excitation of m-cholinergic receptors, n-cholinergic receptors is noted, overdose symptoms are recorded: cyanosis , weakness in the limbs, incontinence , intestinal colic , vomiting, nausea, respiratory disorders, convulsions, muscle twitching, instability of blood pressure, tachycardia or bradycardia, hyperhidrosis , hypersalivation , lacrimation, visual disturbances.
After prolonged contact of Pedilin shampoo with the skin, it is recommended to thoroughly wash with soap and water, take diazepam , atropine in order to reduce feelings of anxiety and reduce muscle twitching.
When ingested, gastric lavage and qualified medical care are recommended.
Contraindications
Pedilin medicated shampoo should not be used if the adult or child has a history of hypersensitivity to the composition or excipients. During pregnancy and lactation, extremely careful use is recommended. It is advisable to consult a medical specialist. You cannot wash your hair with shampoo for a child under two years old.
Analogues of Pedilin
Level 4 ATX code matches: Medifox
Veda 2
Hygia
Permethrin ointment
Spregal
Couple Plus
Nittifor
Analogs are: Nittifor , Permethrin , Permethrin ointment , Hygia .
Other information, analogues
The use of shampoo is permissible for children who have reached the age of five. It is strictly prohibited to use the drug to treat two-year-old children. Do not use the medicine during pregnancy and lactation.
The drug will not be effective if it has expired. It is impossible to completely get rid of parasites if personal hygiene is not observed (for example, if you repeatedly use an untreated comb or comb).
Aerosol Spregal is a good analogue of Pedilin
The drug is available in pharmacies without a prescription. Prices vary depending on regions. It is known that the drug is currently in short supply. Therefore, there are many analogues. These include Spregal aerosol, its approximate price is 800-1000 rubles per 152 g, as well as Pediculen Ultra spray - from 400 to 550 rubles per 150 ml, 200 mg shampoo 600-650 rubles.
Analogues of the drug
“Pedilin” has many analogues, which have both similar and different compositions. It is important to remember that a patient who chooses a drug to treat head lice should first seek advice from a specialist. Only a doctor can prescribe the right drug and its correct dosage, based on the individual characteristics of the patient and the course of the disease. The most common products that help fight parasites include Medifox, cherry water, Hygia, Nittifor and Nix.
Indications for use
The instructions for Pedilin state that the drug for combating parasites is not toxic to animals and people, but is destructive to the mite that causes scabies and to lice. During the use of the drug, when direct contact of parasites with the drug is observed, their nervous system is disrupted, which leads to death. “Pedilin” can be called a gentle product that does not cause irritation to the skin, although it remains on the hair for a long time. This helps ensure that re-infection is unlikely. Doctors recommend using the drug for patients who are faced with head lice and scabies.
Pedilin shampoo against lice and ticks should not be used by pregnant or lactating women or children under two years of age.
special instructions
There are a number of nuances regarding the use of Pedilin, which are important for every patient to adhere to:
- Do not allow the drug to get into the mucous membranes of the body, including the eyes, nasal passages and external genitalia. In cases where Pedilin does end up in the mucous membrane, it is important to rinse the area with clean water.
- After the procedures, treat the comb, towel and bed linen with a disinfectant in order to prevent relapse of the disease.
- Treat hygiene items and bedding of other family members who do not suffer from head lice, but are in close contact with the patient.
Side effects
"Pedilin" of any dosage form may have side effects such as itching and burning of the skin, as well as allergic reactions. In situations where the patient resorts to using the drug for a long time, side effects may develop due to increased dosage. Overdose has the following symptoms:
- low or high blood pressure;
- lacrimation;
- visual impairment;
- increased excitability;
- limb spasms;
- pain in the intestines;
- nausea;
- gagging;
- prostration.
Instructions for use and dosage of Pedilin
Shampoo "Pedilin"
Before using Pedilin shampoo, you will need to slightly wet your hair, since the drug must be applied to damp hair. You will need about 15 milliliters of product, which must be carefully distributed over the roots and length of the hair. Then the patient needs to massage the scalp for about 7 minutes. As soon as these manipulations are completed, wash off the Pedilin with non-hot water using regular shampoo, and then comb out the dead parasites using a special comb.
Emulsion "Pedilin"
The emulsion should be applied to the hair using a special cotton wool sponge, gently rubbing the product into the hair roots. The patient will need about 50 ml of Pedilin, but the exact dosage depends on the hair type of the individual. After applying the drug, the head is wrapped with a bandage and held for approximately 5-7 minutes. After this, the product is washed out with water and shampoo and the dead parasites are combed out with a comb.
Additional instructions
In case of significant lice infestation, it is advisable to carry out complex hair treatment with Pedilin emulsion and shampoo.
In cases where the patient has too many lice, doctors recommend using “Pedilin” as a combination of both emulsion and shampoo. To do this, a person with lice needs to cover their hair with the required amount of product and wrap their head with a bandage. Afterwards, the product should be washed off using not ordinary shampoo, but using Pedilin. It is important to carry out manipulations as follows: wash your hair 2 times with Pedilin shampoo and leave it for about 5 minutes. Then the shampoo should be rinsed off and dead parasites should be combed out from wet hair.
After all parasites have been removed from the hair, it is important to thoroughly rinse and disinfect the comb used for manipulation. In addition, towels and bed linen need to be changed. Experts recommend using the drug not only for a patient who is infected with head lice, but also for all family members living in the same living space.
