ZVEZDOCHKA ENT 0.3% 15ml spray for topical use

Zvezdochka ENT 0.3% 15ml spray for topical use

pharmachologic effect

Benzidamine is a non-steroidal anti-inflammatory drug that belongs to the indazoles group. The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis.

Composition and release form Zvezdochka ENT 0.3% 15ml spray for topical use

Solution - 15 ml:

Active substance: benzydamine hydrochloride;
Excipients: glycerol - 1.5 g, ethanol - 3 g, sodium saccharinate - 15 mg, mint flavor - 15 mg, water - up to 15 ml.

Transparent colorless solution with the smell of mint in a bottle - 15 ml.

Description of the dosage form

Spray for topical use in the form of a clear, colorless liquid, with a characteristic mint odor.

Directions for use and doses

Adults: 2-4 injections of Zvezdochka ENT 2-6 times a day. The duration of treatment with Zvezdochka ENT should not exceed 7 days. If after the recommended period of treatment there is no improvement or new symptoms appear, you should consult your doctor.

Pharmacokinetics

When applied topically, the drug is well absorbed through the mucous membranes and penetrates into inflamed tissues; it is found in the blood plasma in quantities insufficient to obtain systemic effects.

Excretion of the drug occurs mainly by the kidneys, in the form of inactive metabolites or conjugation products.

Indications for use Zvezdochka ENT 0.3% 15ml spray for topical use

Symptomatic treatment of pain syndrome of inflammatory diseases of the oral cavity and ENT organs (of various etiologies);
gingivitis, glossitis, stomatitis (including after radiation and chemotherapy);
pharyngitis, laryngitis, tonsillitis;
candidiasis of the oral mucosa (as part of combination therapy);
calculous inflammation of the salivary glands;
after surgical interventions and injuries (tonsillectomy, jaw fractures)
after treatment and tooth extraction;
periodontal disease;
for infectious and inflammatory diseases requiring systemic treatment - as part of combination therapy.

Contraindications

Hypersensitivity to benzydamine.

The drug should be used with caution in patients with a history of bronchial asthma due to the possibility of developing bronchospasm in them while using the drug.

Effect on the body

It has an anti-inflammatory and local analgesic effect, and has an antiseptic effect against a wide range of microorganisms.

Application Zvezdochka ENT 0.3% 15ml spray for topical use during pregnancy and breastfeeding

It is not recommended for use as a mouth rinse in children under 12 years of age.

Use with caution during pregnancy and lactation.

special instructions

Contains low levels of ethanol. Containing ethanol - less than 100 mg per single dose of Zvezdochka ENT.

Ulcerative lesions of the mucous membrane of the oropharynx may indicate the presence of a more serious pathology.

If symptoms persist for more than 3 days, you should consult your doctor.

The use of the drug is not recommended in patients with hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs.

Side effects Zvezdochka ENT 0.3% 15ml spray for topical use

Local reactions: rarely - dryness, burning in the mouth; frequency unknown - feeling of numbness in the mouth.

Allergic reactions to the components of Asterisk ENT: uncommon - photosensitivity; rarely - hypersensitivity reactions, skin rash, itching; very rarely - angioedema, laryngospasm; frequency unknown - anaphylactic reactions.

Drug interactions

Interaction studies with Zvezdochka ENT spray have not been conducted.

Asterisk ENT spray for local approx 0.15% 30 ml x1

Dosage form Transparent, colorless liquid with a characteristic mint odor. Composition Active ingredient: benzydamine hydrochloride - 45 mg, Excipients: glycerol - 3.0 g, ethanol - 6.0 g, sodium saccharinate - 30 mg, mint flavor - 30 mg, water - up to 30 ml. Pharmacological action Benzydamine is a non-steroidal anti-inflammatory drug that belongs to the group of indazoles. It has an anti-inflammatory and local analgesic effect, and has an antiseptic effect against a wide range of microorganisms. The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis. Benzidamine has an antibacterial and specific antimicrobial effect due to rapid penetration through the membranes of microorganisms with subsequent damage to cellular structures, disruption of metabolic processes and cell lysosomes. Has antifungal effect against Candida albicans. Causes structural modifications of the cell wall of fungi and their metabolic chains, thus preventing their reproduction, which was the basis for the use of benzydamine for inflammatory processes in the oral cavity, including infectious etiology. Pharmacokinetics: When applied topically, the drug is well absorbed through the mucous membranes and penetrates into inflamed tissues; it is found in the blood plasma in quantities insufficient to obtain systemic effects. Excretion of the drug occurs mainly by the kidneys, in the form of inactive metabolites or conjugation products. Side effects Classification of the frequency of side effects of the World Health Organization (WHO): very often - greater than or equal to 1/10, often - from greater than or equal to 1/100 to <1/10, infrequently - from greater than or equal to 1/1000 to <.1/100, rare - greater than or equal to 1/10000 to <.1/1000, very rare - <.1/10000, frequency unknown - cannot be estimated from available data. Local reactions: rarely - dryness, burning in the mouth, frequency unknown - numbness in the mouth. Allergic reactions: infrequently - photosensitivity, rarely - hypersensitivity reactions, skin rash, itching, very rarely - angioedema, laryngospasm, frequency unknown - anaphylactic reactions. If any of the side effects indicated in the instructions get worse, or other side effects not listed in the instructions are noted, you should immediately inform your doctor. Features of sale Available without a prescription Special conditions When using the drug, the development of hypersensitivity reactions is possible. In this case, it is recommended to stop treatment and consult a doctor to prescribe appropriate therapy. Ulcerative lesions of the mucous membrane of the oropharynx may indicate the presence of a more serious pathology. If symptoms persist for more than 3 days, you should consult your doctor. The use of the drug is not recommended in patients with hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs. The drug should be used with caution in patients with a history of bronchial asthma due to the possibility of developing bronchospasm in them while using the drug. The drug Zvezdochka ENT contains a low level of ethanol. Containing ethanol less than 100 mg per single dose. Effect of the drug on the ability to drive vehicles and other mechanisms: Taking the drug does not affect driving vehicles or servicing machines and mechanisms that require concentration. Indications When using the drug, hypersensitivity reactions may develop. In this case, it is recommended to stop treatment and consult a doctor to prescribe appropriate therapy. Ulcerative lesions of the mucous membrane of the oropharynx may indicate the presence of a more serious pathology. If symptoms persist for more than 3 days, you should consult your doctor. The use of the drug is not recommended in patients with hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs. The drug should be used with caution in patients with a history of bronchial asthma due to the possibility of developing bronchospasm in them while using the drug. The drug Zvezdochka ENT contains a low level of ethanol. Containing ethanol less than 100 mg per single dose. Effect of the drug on the ability to drive vehicles and other mechanisms: Taking the drug does not affect driving vehicles or servicing machines and mechanisms that require concentration. Contraindications Hypersensitivity to benzydamine or other components of the drug, children under 3 years of age (for topical spray 0.15%) or children under 18 years of age (for topical spray 0.30%). With caution: Hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs, bronchial asthma (including a history). Pregnancy and lactation: The use of the drug during pregnancy and lactation (breastfeeding) is not recommended due to insufficient clinical data. Drug interactions No interaction studies have been conducted with other drugs.

Source: https://apteka.ru/catalog/zvezdochka-lor-0-15-30ml-flak-sprey-d-mest-prim-_59dba4cb5ace7/ © Apteka.RU Dosage form Transparent, colorless liquid with a characteristic mint odor. Composition Active ingredient: benzydamine hydrochloride - 45 mg, Auxiliary components: glycerol - 3.0 g, ethanol - 6.0 g, sodium saccharinate - 30 mg, mint flavor - 30 mg, water - up to 30 ml. Pharmacological action Benzydamine is a non-steroidal anti-inflammatory drug that belongs to the group of indazoles. It has an anti-inflammatory and local analgesic effect, and has an antiseptic effect against a wide range of microorganisms. The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis. Benzidamine has an antibacterial and specific antimicrobial effect due to rapid penetration through the membranes of microorganisms with subsequent damage to cellular structures, disruption of metabolic processes and cell lysosomes. Has antifungal effect against Candida albicans. Causes structural modifications of the cell wall of fungi and their metabolic chains, thus preventing their reproduction, which was the basis for the use of benzydamine for inflammatory processes in the oral cavity, including infectious etiology. Pharmacokinetics: When applied topically, the drug is well absorbed through the mucous membranes and penetrates into inflamed tissues; it is found in the blood plasma in quantities insufficient to obtain systemic effects. Excretion of the drug occurs mainly by the kidneys, in the form of inactive metabolites or conjugation products. Side effects Classification of the frequency of side effects of the World Health Organization (WHO): very often - greater than or equal to 1/10, often - from greater than or equal to 1/100 to <1/10, infrequently - from greater than or equal to 1/1000 to <.1/100, rare - greater than or equal to 1/10000 to <.1/1000, very rare - <.1/10000, frequency unknown - cannot be estimated from available data. Local reactions: rarely - dryness, burning in the mouth, frequency unknown - feeling of numbness in the mouth. Allergic reactions: infrequently - photosensitivity, rarely - hypersensitivity reactions, skin rash, itching, very rarely - angioedema, laryngospasm, frequency unknown - anaphylactic reactions. If any of the side effects indicated in the instructions get worse, or other side effects not listed in the instructions are noted, you should immediately inform your doctor. Features of sale Available without a prescription Special conditions When using the drug, the development of hypersensitivity reactions is possible. In this case, it is recommended to stop treatment and consult a doctor to prescribe appropriate therapy. Ulcerative lesions of the mucous membrane of the oropharynx may indicate the presence of a more serious pathology. If symptoms persist for more than 3 days, you should consult your doctor. The use of the drug is not recommended in patients with hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs. The drug should be used with caution in patients with a history of bronchial asthma due to the possibility of developing bronchospasm in them while using the drug. The drug Zvezdochka ENT contains a low level of ethanol. Containing ethanol less than 100 mg per single dose. Effect of the drug on the ability to drive vehicles and other mechanisms: Taking the drug does not affect driving vehicles or servicing machines and mechanisms that require concentration. Indications When using the drug, hypersensitivity reactions may develop. In this case, it is recommended to stop treatment and consult a doctor to prescribe appropriate therapy. Ulcerative lesions of the mucous membrane of the oropharynx may indicate the presence of a more serious pathology. If symptoms persist for more than 3 days, you should consult your doctor. The use of the drug is not recommended in patients with hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs. The drug should be used with caution in patients with a history of bronchial asthma due to the possibility of developing bronchospasm in them while using the drug. The drug Zvezdochka ENT contains a low level of ethanol. Containing ethanol less than 100 mg per single dose. Effect of the drug on the ability to drive vehicles and other mechanisms: Taking the drug does not affect driving vehicles or servicing machines and mechanisms that require concentration. Contraindications Hypersensitivity to benzydamine or other components of the drug, children under 3 years of age (for topical spray 0.15%) or children under 18 years of age (for topical spray 0.30%). With caution: Hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs, bronchial asthma (including a history). Pregnancy and lactation: The use of the drug during pregnancy and lactation (breastfeeding) is not recommended due to insufficient clinical data. Drug interactions No interaction studies have been conducted with other drugs.

Source: https://apteka.ru/catalog/zvezdochka-lor-0-15-30ml-flak-sprey-d-mest-prim-_59dba4cb5ace7/ © Apteka.RU Zvezdochka ENT spray for local approx 0.15% 30 ml x1 , Indications for use: Symptomatic treatment of pain syndrome of inflammatory diseases of the oral cavity and ENT organs (of various etiologies):

- gingivitis, glossitis, stomatitis (including after radiation and chemotherapy),

- pharyngitis, laryngitis, tonsillitis,

— candidiasis of the oral mucosa (as part of combination therapy),

- calculous inflammation of the salivary glands,

— after surgical interventions and injuries (tonsillectomy, jaw fractures)

- after treatment and tooth extraction,

- periodontal disease,

For infectious and inflammatory diseases requiring systemic treatment - as part of combination therapy.

Active ingredient, group: Benzydamine, NSAID

Dosage form: topical spray

Contraindications: Hypersensitivity to benzydamine or other components of Zvezdochka ENT, children under 3 years of age (for topical spray 0.15%) or children under 18 years of age (for topical spray 0.30%).

Directions for use and dosage: Topically, after meals.

Spray Zvezdochki ENT for topical use 0.15%:

Adults (including elderly patients) and children over 12 years old: 4-8 injections 2-6 times a day.

Children from 6 to 12 years old - 4 injections 2-6 times a day.

Children from 3 to 6 years old: 1 injection for every 4 kg of body weight, but not more than 4 injections (maximum single dose) 2-6 times a day.

Topical spray 0.3%:

Adults: 2-4 injections of Zvezdochka ENT 2-6 times a day.

The duration of treatment with Zvezdochka ENT should not exceed 7 days. If after the recommended period of treatment there is no improvement or new symptoms appear, you should consult your doctor.

Pharmacological action: Benzydamine is a non-steroidal anti-inflammatory drug that belongs to the group of indazoles. It has an anti-inflammatory and local analgesic effect, and has an antiseptic effect against a wide range of microorganisms. The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis.

Side effects: Local reactions: rarely - dryness, burning in the mouth, frequency unknown - feeling of numbness in the mouth.

Allergic reactions to the components of ENT asterisks: infrequently - photosensitivity, rarely - hypersensitivity reactions, skin rash, itching, very rarely - angioedema, laryngospasm, frequency unknown - anaphylactic reactions.

Special instructions: Contains low levels of ethanol. Containing ethanol - less than 100 mg per single dose of Zvezdochka ENT.

Ulcerative lesions of the mucous membrane of the oropharynx may indicate the presence of a more serious pathology.

If symptoms persist for more than 3 days, you should consult your doctor.

The use of the drug is not recommended in patients with hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs.

The drug should be used with caution in patients with a history of bronchial asthma due to the possibility of developing bronchospasm in them while using the drug.

Interaction: Interaction studies with Zvezdochka ENT spray have not been conducted.