Nicorette, 1 mg/dose, 150 doses, dosed topical spray, mint flavor, 13.2 ml, 2 pcs.

Nicorette fruit-mint nicotine anti-smoking spray 1 mg/dose 150 doses 2 fl

For application to the oral mucosa. The patient should do everything possible to permanently quit smoking while being treated with Nicorette® spray. Adults over 18 years of age.

Nicorette® spray should be used at the moment when an irresistible urge to smoke arises. After preparing the spray for use (see below for Instructions for Use when using the spray for the first time), place the tip of the spray as close to your open mouth as possible. Press the dispenser from above, thus releasing one dose of the drug into the oral cavity; Avoid getting the spray on your lips. To prevent the substance from entering the respiratory tract, do not inhale when pressing the dispenser.

For best results, do not swallow saliva for several seconds after injection.

While using the spray, eating and drinking is not recommended.

If symptoms of overdose appear (see section “Overdose”), use of the drug must be stopped immediately.

Complete smoking cessation:

Nicorette® Spray should be used in all cases of craving for smoking or to prevent cravings in situations that may provoke them. Smokers who want or are able to quit smoking immediately should immediately replace smoking cigarettes with Nicorette® spray and, as soon as possible, reduce the number of injections until they stop completely.

If you completely quit smoking, take 1 or 2 injections during the period of time when you usually smoked a cigarette, as well as if you have a craving for smoking. If after a single injection the craving for smoking does not decrease within a few minutes, a second injection should be made. If two doses are required, subsequent application of the spray may consist of 2 consecutive injections.

Every hour you are allowed to take no more than 4 dosed injections of the spray. Do not inject more than 2 doses of spray at a time or use more than 64 doses per day (or 4 doses per hour for 16 hours).

Each bottle contains at least 150 doses.

The average course of use of the spray at the indicated dose is 6 weeks. Then you should begin to reduce the number of injections so that by the end of the 9th week the number of doses is half the average number of doses per day received in the first 6 weeks, and during the 12th week - no more than 4 doses per day. When the daily dose drops to 2-4 injections, use of the spray should be discontinued.

After completion of therapy, to prevent a return to smoking, patients can use Nicorette® spray if they have an irresistible urge to smoke. In such situations, you can make 1 injection, and if after a single injection the craving for smoking does not decrease within a few minutes, you should make a second injection. In this case, you should not exceed 4 dosed injections per day.

Regular use of the spray for more than 6 months is usually not recommended, but some patients may require longer therapy to avoid relapse into smoking.

Reducing the number of cigarettes you smoke:

Smokers wishing to reduce the number of cigarettes they smoke should use the spray as needed between smoking episodes to increase the time between smoking and to reduce smoking as much as possible.

Once readiness is felt, smokers should aim to quit completely.

After quitting smoking, you should follow the recommendations for therapy and gradual dose reduction indicated above for complete smoking cessation.

Behavioral therapy and psychological support usually increase treatment success. Those who have managed to quit smoking but find it difficult to give up the spray are advised to consult a doctor for medical help.

Temporary smoking cessation:

The spray can be used during periods when it is necessary to abstain from smoking, for example, when in places where smoking is prohibited, or in other situations when it is necessary to abstain from smoking. The maximum daily dose for temporary smoking cessation is 64 doses.

In combination with a transdermal patch:

For smokers with a severe nicotine addiction (more than 20 cigarettes per day) or who experience an irresistible craving for smoking, or smokers who have not been able to quit smoking using only one type of nicotine replacement therapy, it is possible to use Nicorette® oral mucosal spray in combination with Nicorette® transdermal patch to quickly relieve smoking cravings.

The patch is applied to an intact area of ​​skin immediately after waking up in the morning and removed before going to bed. The patch should be applied to dry, clean, intact, hair-free skin, such as the thighs, upper limbs or chest. It is necessary to change the application site every day: do not use the same area for two consecutive days. After applying the patch, wash your hands thoroughly to avoid eye irritation from possible nicotine contact.

Initial combination therapy: Treatment should begin with a 25 mg/16 hour patch (stage 1) in combination with a 1 mg/dose spray. Usually 13 doses of spray per day are sufficient. The maximum daily dose of the spray is 32 doses.

Patients should completely stop smoking during therapy. Usually the general course of treatment lasts for 8 weeks. After this, the dose of nicotine should be gradually reduced.

Cancellation of combination therapy:

Combination therapy can be discontinued in two ways.

Method 1: Over the next 2 weeks, switch from the 25 mg/16 hour patch (Stage 1) to the 15 mg/16 hour patch (Stage 2), and then, over the next 2 weeks, to the 10 mg/16 hour patch ( stage 3), while maintaining, if necessary, the number of doses of Nicorette® spray used, as with Initial therapy. Next, the number of doses of the spray is gradually reduced until complete withdrawal for the time that the patient needs depending on his needs, but no later than 12 months after the start of combination therapy.

Method 2: involves completely removing the patch immediately after completing the Initial Therapy phase. Next, gradually reduce the number of doses of Nicorette® spray until complete withdrawal during the time that the patient needs depending on his needs, but no later than 12 months after the start of combination therapy.

Children and teenagers under 18 years of age.

The drug is not recommended for use by persons under 18 years of age. There is no experience in treating adolescents under 18 years of age with the spray.

Nicorette

Adults and elderly people

The patch is applied to an intact area of ​​skin immediately after waking up in the morning and removed before going to bed. Treatment with this drug simulates the fluctuations in nicotine concentrations throughout the day in a smoker; Moreover, during sleep, nicotine does not enter the body. The use of a transdermal patch during the day does not cause the disturbances observed when nicotine enters the body during sleep.

Heavy smokers (more than 20 cigarettes per day) are recommended to start with stage 1 of therapy, using 1 patch of 25 mg/16 hours daily for 8 weeks. Then begin a gradual reduction in the dose of the drug: 1 patch of 15 mg/16 hours, daily, for 2 weeks, and then - 1 patch of 10 mg/16 hours, daily, for 2 weeks.

Light smokers (10-20 cigarettes per day) are recommended to start therapy with stage 2 (15 mg) for 8 weeks, then reduce the dose to stage 3 (10 mg) for the final 4 weeks.

In most cases, the use of a transdermal patch for more than 6 months is not recommended. However, some people may need longer therapy to avoid relapse into smoking.

How to apply a transdermal patch (patient information)

The Nicorette® patch should be applied to dry, clean, intact, hair-free skin, such as the thighs, upper limbs or chest. It is necessary to change the application site every day: do not use the same area for two consecutive days.

1. Wash your hands thoroughly before applying the patch.

2. Use scissors to cut the patch package along the edge as indicated on the package. Select a clean, dry, hair-free area of ​​skin (such as the thigh, upper limb, or chest).

3. Remove one half of the silver aluminized protective film without touching the adhesive surface of the patch.

4. Fasten the part of the patch freed from the protective film to the skin and remove the remaining half of the silver aluminized protective film.

5. Press the patch firmly against the skin with your palm or fingertips.

6. Run your finger along the edge of the patch, making sure it is firmly attached.

In combination with chewing gum

The Nicorette® patch can also be used in conjunction with Nicorette® chewing gum at a dosage of 2 mg in situations where, while using the patch, a person continues to periodically experience an irresistible urge to smoke, or if it was not possible to quit smoking using only chewing gum or only the patch. In combination with the Nicorette® patch, Nicorette® chewing gum with a dosage of 2 mg allows you to quickly relieve strong urges to smoke when needed.

Initial therapy

Treatment should begin with a 25 mg/16 hour patch (stage 1) in combination with 2 mg chewing gum. In this case, use at least 4 chewing gums (2 mg dosage) per day; usually 5-6 chewing gums are enough. The number of chewing gums should not exceed 15 pieces/day. Usually the general course of treatment lasts for 8 weeks. After this, the dose of nicotine should be reduced gradually.

The patch is applied immediately after waking up in the morning and removed before going to bed. The Nicorette® patch should be applied to dry, clean, intact, hair-free skin, such as the thighs, upper limbs, or chest. It is necessary to change the application site every day: do not use the same area for two consecutive days.

After applying the patch, you should wash your hands thoroughly to avoid eye irritation from possible nicotine contact.

Cancellation of combination therapy

Combination therapy can be discontinued in two ways.

Method 1: Over the next 2 weeks, switch from the 25 mg/16 hour patch (Stage 1) to the 15 mg/16 hour patch (Stage 2), and then over the next 2 weeks to the 10 mg/16 hour patch (Stage 3). ), while maintaining the amount of chewing gum used at a dosage of 2 mg, as in initial therapy. Next, the amount of chewing gum is gradually reduced until complete abolition for the time that a person needs depending on his needs, but no later than 12 months after the start of combination therapy.

Method 2: consists of completely canceling the patch immediately after the end of the initial therapy phase. Next, the amount of chewing gum is gradually reduced at a dosage of 2 mg until complete discontinuation for the time that a person needs depending on his needs, but no later than 12 months after the start of combination therapy.

Recommended dose

Please note that only a new patch should be applied the next day.

Overdose

Excessive intake of nicotine from replacement therapy and/or smoking may cause overdose symptoms.

Nicotine overdose can occur with the simultaneous use of several transdermal patches, in the presence of dependence on very low doses, as well as when combining transdermal patches with other sources of nicotine, incl. smoking.

Overdose symptoms that develop during acute nicotine poisoning include: nausea, increased salivation, abdominal pain, diarrhea, sweating, headache, dizziness, hearing impairment and severe weakness. When high doses are used, these symptoms may be followed by decreased blood pressure, weak and irregular pulse, difficulty breathing, prostration, collapse and generalized convulsions.

Nicotine in doses tolerated by adult smokers can cause severe symptoms of intoxication in children, incl. with fatal outcome.

Treatment: Nicotine use should be stopped immediately and symptomatic treatment should be prescribed. Activated carbon reduces the absorption of nicotine from the gastrointestinal tract.