Amlodipine analogues and substitutes without side effects - complete list

About Amlodipine

Today, the most popular drug in cardiology and neurology is Amlodipine and its analogues and substitutes without side effects. All varieties of this medicine have a common active substance - amlodipine. Release form: tablets.

The drug has analogues of domestic and foreign production. They all vary in price and number of side effects. Independent selection of the drug is strictly prohibited. Only a specialist will be able to select the most effective and safe remedy on an individual basis.

Price of Amlodipine and its analogues

Domestic analogues

The Russian drug Amlodipine can be purchased at an affordable price. Thanks to this, patients with different income levels can use the drug. The medicine has some contraindications. There are analogues of Amlodipine on the pharmaceutical market, among which you can choose a replacement for the original drug.

Amlotop

The main active component is amlodipine benzylate. This analogue and substitute for amlodipine without side effects is in the first line of drugs for high blood pressure. "Amlotop" is prescribed for complex treatment (hypertension) and monotherapy.

Indications:

• – cardiac ischemia;
• – angina pectoris;
• – prevention of myocardial infarction and stroke;
• – vasospasms;
• – vasoconstriction.

Restrictions:

• – pregnancy;
• – lactation;
• – children under 18 years of age.

Amlodifarm

Treatment with the drug has a beneficial effect on the supply of oxygen to myocardial cells. In the presence of vasospastic angina, the medicine improves blood circulation and the functioning of cardiomycytes.

Main properties of "Amlodipharma":

• – blocks the occurrence of spasm in the coronary vessels;
• – reduces the intensity and frequency of attacks in patients with angina pectoris;
• – has a long-lasting hypotensive effect;
• – eliminates symptoms in patients with Raynaud's syndrome;
• – a good analogue and substitute for amlodipine without side effects.

Vero-Amlodipine

The drug is a direct analogue and substitute for amlodipine without side effects. The active substance is amlodipine besylate. Country of origin: Russia, pharmaceutical corporation Veropharm.

One Vero-Amodipine tablet contains 5 milligrams of the active ingredient. You can buy the drug for 60-100 rubles (packaging).

Lercanidipine-S3

Manufacturer – Russia. The tablets contain the active substance – lercanidipine (BMKK). The drug helps relax vascular smooth muscles. Does not affect the heart muscles. Blood pressure decreases gently and gradually. The drug is gentle on the kidneys. It is an analogue and substitute for amlodipine without side effects.

There are several domestic analogues with the least number of adverse reactions:

• – “Lercanidipine-S3”;
• – “Lercanorm”;
• - "Lernikor".

These drugs can be rationally used in the treatment of hypertension (stages 1 and 2).

Norvavdin

The drug is prescribed in the presence of the following diseases:

1. – angina pectoris (stable, Prinzmetal);
2. - arterial hypertension.

The drug is suitable for patients who are refractory to beta-blockers and nitrate therapy.

• analogue and substitute of amlodipine without side effects

Omelar Cardio

The active substance is dihydropyridine. The drug has antihypertensive and antianginal effects. Calcium is blocked through vascular smooth muscle cells and myocardium. The same applies to amlodipine analogues and substitutes without side effects.

Felotenz Retard

The anti-ischemic result depends on the dosage of the drug. The use of tablets blocks complications and the size of the heart attack. "Phelotenz Retard" affects calcium ions in the channels of cell membranes. Due to this, the conductivity and contraction of vascular smooth muscles decreases.

• a good analogue and substitute for amlodipine without side effects

The high level of arteriolar smooth muscle selectivity does not have a negative effect on cardiac conduction. This effect is only possible when using therapeutic doses.

Phenigidine

According to him, it promotes the expansion of coronary and peripheral vessels, reduces elevated oxygen levels, negatively affects inotropes, lowers the blood pressure index, reduces the load on the myocardium and peripheral vascular resistance. Amlodipine analogue.

When is it necessary to replace Amlodipine?

Amlodipine tablets are most often well tolerated by the human body, but in some cases its use is accompanied by side effects:

• with prolonged use, a person’s limbs swell, their convulsions and trembling bother them;
• heart rhythm disturbances;
• painful spasms in the chest;
• hypotension;
• attacks of headache;
• stomach pain;

• bloating;
• fainting, depression;
• allergic skin rashes.

Reviews from patients confirm the high effectiveness of Amlodipine in the treatment of arterial hypertension.

But this drug is distinguished by its ability to accumulate fluid in the tissues - as a result, about 45% of patients experience side effects in the form of swelling of the legs and feet.

However, in most cases, diuretics do not help solve the problem. In case of pronounced swelling, the attending physician selects a pharmacological replacement with a similar therapeutic effect and fewer side effects.

Foreign analogues

Amlodipine has several foreign analogues and substitutes without side effects, which are distinguished by a small number of adverse reactions. This is due to the fact that during the manufacture of drugs, the raw materials undergo scrupulous cleaning.

Canephron analogues are cheap and their prices

Amlodigamma

Elderly people should take these tablets with caution. At the same time, the dosage of the drug for them is the same as for patients of other ages. Increasing the dosage is allowed only under the close supervision of a specialist.

Amlovas

This drug belongs to the group of calcium antagonists. One Amlovas tablet gently lowers blood pressure throughout the day. The full course of treatment lasts from 14 to 21 days. After its passage, a persistent hypotensive effect occurs. Can be used as an analogue and substitute for amlodipine without side effects.

The medicine helps improve the physical capabilities of the body.

Indications:

• – hypertension;
• – angina pectoris;
• – arrhythmia.

Often prescribed in combination with diuretics, beta-blockers and monotherapy.

Amlodak

The Indian drug relaxes the muscles of blood vessels and also promotes the expansion of the coronary arteries. An effective analogue and substitute for amlodipine without side effects.

• You can buy Amlodak for 330 rubles.

Amlodil

The drug is based on dihydropyridine. This substance belongs to the second generation calcium channel blockers. Amlodil has an antianginal and hypotensive effect. Amlodipine analogue.

Amlocard-Sanovel

While taking the drug, it is important to monitor your weight and also visit the dentist. The medicine can cause bleeding, sensitivity and gum hyperplasia. A good replacement for amlodipine.

Amlonorm

The drug is prescribed in the presence of the following diseases:

• – angina pectoris (stable);
• – hypertension;
• – Prinzmetal syndrome.

Use in complex treatment is allowed.

Zanidip-Recordati

The drug relaxes the smooth muscles of blood vessels. It also has a prolonged antihypertensive effect. A positive result is noticeable 6 hours after oral administration of the tablet.

The effect lasts throughout the day. Zanidip-Recordati does not have a negative inotropic effect. This is due to a high level of selectivity for vascular smooth muscle. The drug can be used as an analogue and substitute for amlodipine without side effects.

Isradipin

The drug is prescribed to patients suffering from arterial hypertension (mild or moderate) as an analogue and substitute for amlodipine without side effects.

Blood pressure decreases on the 6th day of treatment. The most stable result occurs after 3-4 weeks of therapy.

Despite the fact that the drug's instructions indicate only one indication for use, doctors often prescribe the drug for the following diseases:

• – heart failure (sudden pressure surges);
• – angina pectoris.

In such situations, the doctor selects an individual dosage and regimen of the drug.

Kalchek

The main advantage of the tablets is their safety for blood lipid composition. They exhibit activity at the antithrombotic and antiatherosclerotic level. They significantly increase the rate of blood filtration and have a lethal natriuretic effect. Amlodipine analogue.

Karmagip

Taking the drug may cause increased drowsiness and dizziness.

In this regard, it is recommended to exercise caution in the following patients:

• – drivers;
• – workers of hazardous professions;
• – professions that require high concentration of attention.

Corvadil

The drug is contraindicated in pregnant and lactating women. It has antispasmodic and hypotensive effects. Can be used as an alternative to amlodipine.

Cordafen

The drug selectively blocks calcium channels.

The use of the medicine involves:

• – decreased tone of the vascular walls;
• – relieving spasms;
• – prevention of cardiovascular diseases;
• – gently lowers blood pressure.

The drug helps reduce calcium levels in the myocardium, muscles of arteries and arterioles. The medicine is prescribed to patients with diseases of the cardiovascular system, hypertension and Raynaud's syndrome. Taking the drug does not have a negative effect on the venous system and is considered a good analogue and substitute for amlodipine without side effects.

From the cardiovascular system "Cardafen":

• – normalizes peripheral pressure;
• – relieves excess load from the left cardiac ventricle (increased diastole);
• – increases cardiac output;
• – increases blood circulation in the coronary arteries.

A positive result is noticeable within 20 minutes. Duration – 5-6 hours.

Cordaflex

Treatment with the drug normalizes the amount of incoming calcium ions, which are disrupted in the presence of arterial hypertension and other pathological changes.

The drug promotes the dilation of arterial vessels and reduces spasms. Thanks to the active substance, the load on the myocardium is reduced.

In patients, blood circulation in the myocardial zone improves, and the number of active collaterals increases. An analogue and substitute for amlodipine without side effects.

Corinfar

The medicine is a calcium antagonist. Thanks to this medication, excessive contraction activity in the vessels is reduced and their tone is reduced. They become elastic, so the coronary arteries and arterioles dilate.

Just like other similar drugs, Corinfar reduces the myocardial oxygen demand. This can significantly reduce the load on the heart. At the same time, the coronary arteries expand, blood circulation in the peripheral and cerebral vessels returns to normal.

The main active ingredient of the drug is nifedipine. This component blocks the possible occurrence of sclerotic pathologies in blood vessels, as well as atherosclerotic growths.

Corinfar is quickly absorbed, so visible results are observed within 15-20 minutes after taking the tablet. A good analogue of amlodipine.

Lacipil

Release form: tablets. The drug has a hypotensive and selective effect on calcium channels in vascular smooth muscles.

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Lerkamen

Taking the drug may cause adverse reactions:

• – increased fatigue;
• – asthenia;
• – dizziness;
• - drowsiness.

It is recommended that drivers of vehicles and workers in hazardous professions take the tablets with extreme caution.

Nifecard

Main properties of the drug:

• – improves myocardial function;
• – reduces heart rate;
• – reduces myocardial oxygen demand;
• – promotes the expansion of peripheral arteries;
• – reduces blood pressure;
• – reduces the load on the heart;
• – does not have a negative effect on the sinoatrial nodes;
• – is an analogue and substitute for amlodipine without side effects;
• – stimulates blood circulation in the kidneys;
• – may cause minor natriuresis.

Norvask

The manufacturer of this drug is German. "Norvasc" and "Amlodipine" differ in form. The octagonal volumetric tablet looks like an emerald.

The properties of this analogue and substitute for amlodipine without side effects are the same as those of Amlodipine. The drug has been thoroughly tested and controlled by randomized trials. Other analogues of amlodipine produced in Russia have not undergone such thorough research.

When choosing between an original drug and its analogue, of course, it is better to give preference to a branded drug.

"Norvasc" and "Tenox" have virtually no side effects and also provide quick clinical results.

Among all the substitutes for Amlodipine, doctors prefer these drugs. They do not provoke swelling of the legs, gently and gradually reduce pressure, and give a gradual antiarrhythmic result.

The choice of blood pressure medication must be approached with all responsibility. The chosen drug must be agreed with your doctor. If negative reactions occur from taking the pills, you should urgently visit a specialist. The doctor will select the most suitable analogue for the given situation.

Normodipine

A single dose of the medicine provides an effect for the whole day.

Thanks to Normodipin, the following changes occur in the body:

• – myocardial ischemia becomes less pronounced;
• – blood pressure is gently reduced;
• – relaxes the smooth muscles of the arteries;
• – prevents the occurrence of spasms in the arteries;
• – blocks the possible occurrence of angina attacks (can be prescribed for prevention);
• – does not disrupt the metabolism in the body.

The effectiveness of therapy with this medicine depends on the correct dosage. The drug can be used as an analogue and substitute for amlodipine without side effects.

Osmo-Adalat

The drug is prescribed in the presence of the following diseases:

• – all types of angina pectoris;
• – hypertension;
• – Raynaud's disease (syndrome);
• – spasms in the coronary arteries;
• – stenosis of the coronary arteries.

Stamlo M

The main active substance is dihydropyridine. The drug is a representative of second generation calcium channel blockers. An effective analogue of amlodipine.

The drug acts at the hypotensive and antianginal level.

Prescribed for the following diseases:

• - arterial hypertension;
• – angina pectoris.

The tablets are taken orally, regardless of meals.

Tenox

The main active substance is amplodipine maleate. The medication belongs to the group of antihypertensive drugs that block calcium channels.

Indications:

• - arterial hypertension;
• – angina pectoris (stable, unstable);
• – different etiologies of cardiac ischemia.

"Tenox" affects the muscles of the arteries, but does not affect cardiomyocytes. Taking the drug helps to significantly reduce muscle tone.

Thanks to this, the following changes occur:

• – the resistance of the vascular walls decreases significantly;
• – the heart rhythm is brought back to normal;
• – the risk of left ventricular hypertrophy is reduced.

And in patients with angina pectoris and arrhythmia, the frequency of attacks decreases. Taking the medicine helps prevent a heart attack. A one-time use of the medicine can normalize blood pressure. The effect lasts throughout the day.

Foridon

The pharmacological properties of this drug are similar to Nifedipine. "Foridon" is a calcium antagonist. May be prescribed as an alternative to amlodipine.

Taking the drug provides:

• – decrease in blood pressure (hypotensive effect);
• – relieves spasms (antispasmodic effect);
• – promotes dilation of heart vessels (coronary dilation effect).

If you choose a drug to lower blood pressure, then Nifedipine is much more effective than Foridon.

Escordicore

- Iceland. Prescribed to lower blood pressure. The medicine acts by reducing the tone in peripheral vessels.

The drug may cause adverse reactions:

• – shortness of breath;
• -swelling;
• - nausea;
• - headache;
• – drowsiness;
• – allergic rashes.

Brief summary

Amlodipine is an effective drug used to treat arterial hypertension, angina pectoris, and diseases of the cardiovascular system. It effectively restores myocardial function and reduces the risk of developing tachycardia attacks.

The pharmacological agent has a number of side effects, including swelling of the legs, cramps and trembling of the limbs, painful spasms in the abdomen and chest. In case of side effects, it is recommended to replace Amlodipine with an analogue drug with an identical hypotensive effect and fewer side effects.

Amlodipine substitutes that do not cause leg swelling

The most common adverse reaction to the drug is swelling of the legs. In such situations, the doctor is forced to immediately transfer the patient to amlodipine analogues and substitutes without side effects. Let's consider the most well-known substitutes that do not provoke swelling of the lower extremities.

Perindopril

The drug is an ACE inhibitor. After blocking angiotensin-1 and angiotensin-2, blood vessels dilate.

Due to this effect, the following changes occur in the patient’s body:

• – aldosterone decreases;
• – renin activity increases;
• – blood pressure decreases;
• – myocardial cells begin to work in a normal rhythm;
• – the risk of tachycardia is significantly reduced.

The drug is prescribed to patients with heart failure. An analogue and substitute for amlodipine without side effects.

After taking Perindopril, positive effects are observed:

• – pressure in the ventricles of the heart decreases by 80%;
• – the number of cardiac emissions increases by 45%;
• – blood flow in the peripheral system increases by 60%.

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Lortenza

The combined antihypertensive drug contains the following active components:

• – amlodipine (calcium antagonist);
• – losartan (angiotensin-2 blocker).

When taking the medicine, calcium ions entering through cell membranes are blocked. Thanks to this, relaxation of the myocardial muscles and arterial membranes occurs.

This effect on the membranes of blood vessels helps to increase the speed of blood flow in the arteries and enhances the release of the heart muscles. This effect helps to gently lower blood pressure.

• – an effective analogue and substitute for amlodipine without side effects.

Taking the drug can prevent the occurrence of ischemia in the myocardium and arteries of the brain. Perindopril is prescribed for preventive purposes. Taking the drug will reduce the risk of heart attack (cardiac and cerebral).

Tenliza

The drug is prescribed to patients with essential hypertension. Tenliza perfectly corrects and controls blood pressure.

The main active ingredients of the drug are amlodipine and lisinopril. These components are absorbed into the bloodstream after 7 hours. The maximum level of concentration is observed within 9 hours. Amlodipine analogue.

The medicine does not have accumulative properties. It can be canceled or replaced with another medication without consequences.

Cheap analogs of "Amlodipine"

The quality of a product does not always depend on its cost. The drug "Amlodipine" has high-quality analogues and substitutes without side effects at an affordable cost. Moreover, they have the same mechanism of action. Let's look at some of them below.

Amlorus

The drug belongs to the second generation calcium blockers. The active substance is dihydropyridine.

This drug has a number of properties:

• – affects the dilation of arteries inside the heart. This improves blood circulation in the myocardium and ensures sufficient oxygen supply to cardiomyocytes;
• – helps reduce the load on the myocardium;
• – reduces the number of attacks in patients with angina pectoris;
• – prevents the development of pathological changes in the cardiac ventricles;
• – reduces blood pressure as gently and quickly as possible.

The drug is prescribed to patients with hypertension and heart failure. Amlorus is also excellent for preventive measures for people with narrowed blood vessels. It is an analogue and substitute for amlodipine without side effects.

Vero-Nifedipine

The medicine belongs to the second class calcium channel blockers. The active substance is nifedipine. The drug works by selectively blocking “slow” calcium channels.

"Vero-Nifedipine" uncouples the processes of excitation and contraction in the myocardium. Reduces spasm and dilates coronary and peripheral (mainly arterial) vessels, reduces blood pressure, total peripheral vascular resistance, reduces afterload, myocardial tone, myocardial oxygen demand and increases the duration of distolic relaxation of the left ventricle.

The drug has the following properties:

• – unloads the myocardium;
• – improves blood circulation in blood vessels.

Taking the medicine does not affect the heart rhythm and conductivity in the myocardium. Can be used as a substitute for amlodipine.

Amlodil and Amlopril

These two calcium antagonists have a similar mode of action and composition:

• – counteract the influx of calcium into the myocardial zone;
• – promote relaxation of the heart muscles;
• – normalizes high pressure in the arteries.

"Amlodil" and "Amlopril" - two analogues of amlodipine, normalize the heart rhythm and prevent a possible heart attack. Good coronary blood flow ensures normal oxygen levels in cardiomycytes.

These medications are prescribed to patients with hypertension, angina pectoris, and also after a heart attack.

Semlopin

The drug is a calcium channel antagonist. The active substance is amlodipine besylate. One tablet can lower your blood pressure throughout the day. The full course of treatment gives a stable effect.

Taking the drug reduces the load on the heart and supplies oxygen to the heart muscles. Patients have a reduced risk of myocardial ischemia and improved physical condition.

Amlodipine - description of the drug

Amlodipine is a medicine prescribed to treat hypertension in adults. It refers to calcium channel blockers that act on the muscle tissue cells of the arterial membranes, helping to restore their elasticity.

The pharmacological drug is recommended to be taken to lower blood pressure in patients suffering from angina pectoris, coronary heart disease, chronic heart failure or bronchial asthma.

Amlodipine tablets can be taken both for monotherapy and in combination with other medications. The main active ingredient in the medication is amlodipine besylate. The medicine has contraindications for use:

• arterial hypertension;
• cardiogenic shock, collapse;
• period of pregnancy and breastfeeding;

• hypersensitivity to the active component.

Amlodipine is prescribed with extreme caution to patients with diabetes mellitus, chronic heart failure, renal dysfunction, and also during the recovery period after a recent myocardial infarction. In such cases, the cardiologist selects effective substitute drugs with minimal side effects.