Instructions for use AIRTAL® powder
The simultaneous use of Airtal® and other NSAIDs, including selective COX-2 inhibitors, should be avoided.
Adverse events can be minimized by using the drug at the lowest effective dose and reducing the duration of treatment necessary to control symptoms.
Effect on the gastrointestinal tract
Bleeding, ulceration or perforation of the gastrointestinal tract with a fatal outcome was observed when taking any NSAIDs during any period of treatment, both with and without dangerous symptoms, both with and without a history of serious pathological conditions of the gastrointestinal tract.
The risk of bleeding, ulceration and gastrointestinal perforation increases with increasing dose of NSAIDs in patients who have had an ulcer, especially if it was accompanied by hemorrhage or perforation, and in elderly patients. These patients should take the drug at the minimum effective dose. In such cases, combination therapy with the use of protective drugs (for example, misoprostol or proton pump inhibitors) is necessary, and such therapy is also necessary for patients who take small doses of acetylsalicylic acid or other drugs that can negatively affect the gastrointestinal tract.
Patients with gastrointestinal diseases, including elderly patients, should report any unusual gastrointestinal symptoms (especially bleeding), including when taking the drug for the first time. Particular caution should be exercised when prescribing the drug to patients who are concomitantly taking medications that may increase the risk of bleeding or ulceration, such as systemic corticosteroids, anticoagulants (such as warfarin), selective serotonin reuptake inhibitors, or antiplatelet agents (such as acetylsalicylic acid).
If bleeding or gastrointestinal ulcers occur in patients taking Airtal®, the drug should be discontinued.
Effect on the cardiovascular system and central nervous system
For patients with hypertension and/or mild to moderate congestive heart failure, appropriate monitoring and special instructions are required. Fluid retention and edema associated with NSAIDs have been reported.
Clinical studies and epidemiological data indicate that the use of some NSAIDs (particularly at high doses and during long-term use) may not significantly increase the risk of arterial thrombotic events (eg, myocardial infarction or stroke). There is no reliable data on the absence of this risk when taking aceclofenac.
In patients with uncontrolled hypertension, heart failure (NYHA functional class I), congestive heart failure, cardiovascular risk factors (eg, hypertension, hyperlipidemia, diabetes mellitus, and smoking), and a history of cerebral hemorrhages, aceclofenac should be prescribed with extreme caution.
Aceclofenac should be prescribed with caution and medical supervision should be provided for the following conditions, as there is a risk of exacerbation of the disease:
- symptoms indicating the presence of gastrointestinal disease, including its upper and lower sections;
- indications in the anamnesis of ulcers, bleeding or perforation of the gastrointestinal tract;
- ulcerative colitis;
- Crohn's disease;
- tendency to bleeding, SLE, porphyria, disorders of hematopoiesis and hemostasis.
Aceclofenac should be used with caution and under medical supervision in patients with a history of hemorrhagic stroke.
Effect on the liver and kidneys
Taking NSAIDs may cause a dose-dependent decrease in prostaglandin formation and sudden renal failure. The importance of prostaglandin in maintaining renal blood flow should be considered when taking the drug in patients with impaired cardiac, renal or hepatic function, in those receiving diuretics or in patients after surgery, as well as in elderly patients.
Caution should be exercised when using the drug in patients with mild or moderate impairment of liver and kidney function, as well as in patients with other conditions predisposing to fluid retention in the body. In these patients, the use of NSAIDs may lead to impaired renal function and fluid retention. Caution should also be exercised when using Airtal® in patients receiving diuretics or in individuals with an increased risk of hypovolemia. A minimum effective dose and regular medical monitoring of kidney function are required. Kidney side effects usually resolve after discontinuation of aceclofenac.
Aceclofenac should be discontinued if changes in liver function tests persist or worsen, clinical signs or symptoms of liver disease develop, or other manifestations (eosinophilia, rash) occur. Hepatitis can develop without prodromal symptoms.
The use of NSAIDs in patients with hepatic porphyria may precipitate an attack.
Hypersensitivity and skin reactions
Like other NSAIDs, the drug may cause allergic reactions, including anaphylactic/anaphylactoid reactions, even if the drug is taken for the first time. Severe skin reactions (some of which can be fatal), including exfoliative dermatitis, Stevens-Johnson syndrome and toxic epidermal necrolysis, have been very rare after taking NSAIDs. The highest risk of these reactions occurring in patients is observed at the beginning of taking the drug, and the development of these adverse reactions is observed during the first month of taking the drug. If skin rash, lesions on the oral mucosa, or other signs of hypersensitivity occur, stop taking aceclofenac.
In special cases, complications may occur with chickenpox:
- serious skin and soft tissue infections. At present, the role of NSAIDs in worsening the course of this infection cannot be ruled out. Therefore, you should avoid taking Airtal® for chickenpox.
Hematological disorders
Aceclofenac may cause reversible inhibition of platelet aggregation.
Respiratory system disorders
Caution should be exercised when using the drug in patients with bronchial asthma currently or in history, because taking NSAIDs may trigger the development of sudden bronchospasm in such patients.
Elderly patients
Caution should be exercised when using the drug in elderly patients, because they are more likely to experience side effects (especially bleeding and gastrointestinal perforation) when taking NSAIDs. Complications can be fatal. In addition, older patients are more likely to suffer from kidney, liver or cardiovascular diseases.
Long-term use
All patients receiving long-term treatment with NSAIDs should be closely monitored (complete blood count, liver and kidney function tests should be periodically monitored).
Use in pediatrics
There is no data on the effectiveness and safety of taking the drug in children
.
Impact on the ability to drive vehicles and operate machinery
Patients who have experienced weakness, dizziness, vertigo, nausea or other central nervous system symptoms while taking the drug should not drive vehicles or operate dangerous machinery during the treatment period.
What are Aertal tablets for?
The active ingredient of Aertal is aceclofenac. This is an anti-inflammatory drug with an analgesic effect. The tablets are taken for severe pain in the joints and tissues; the drug is especially often used for toothache, when it is not possible to quickly get to the dentist. In addition, sudden pain in the lumbar region can also be easily eliminated by taking the Aertal tablet.
Food intake does not affect the absorption and activity of the components. For severe and persistent pain, take the drug twice a day, one tablet. Exceeding the daily dose is not recommended to avoid negative reactions.
What is Aertal powder from?
Powder is a type of dosage form. It is intended for preparing a suspension. A single dose of the drug is packaged in a sachet. The advantage of using the powder is its rapid absorption. The tablet requires time to be broken down and processed in the gastrointestinal tract, and the powder, once in the stomach, begins to be absorbed into the blood without waiting for delivery to the intestines. The active substance contained in the tablets is contained in the same volume in one sachet.
Another advantage of using powder is the ability to accurately adjust the dose. For example, people with kidney or liver failure need to reduce the single dose by half. By dividing the contents of the package into two parts, it is easy to prepare a suspension of the desired concentration.
Aertal or Xefokam: which is better?
Ksefokam, like Airtal, is an anesthetic drug. Its activity is primarily observed in rheumatoid arthritis, osteoarthritis and other types of joint and bone pain. However, unlike Airtal, Xefocam is based on another active substance - lornoxicam, which does not in any way affect the level of inflammation and the patient’s body temperature. The drug is suitable for symptomatic use and relief of sudden pain.
Adverse reactions for both drugs are identical. Long-term use can cause anemia, thrombocytopenia, insomnia, and depression. When choosing between medications, you need to pay special attention to individual intolerance to the components, and the need to relieve inflammation and normalize the temperature.
Both drugs are contraindicated during pregnancy and breastfeeding, since their active ingredients are instantly and almost completely absorbed into the blood. These drugs are also not prescribed to patients under 18 years of age. Bronchial asthma is a direct contraindication to the use of both drugs, since both of them can cause bronchospasm.
How to replace the drug Airtal
The group of non-steroidal anti-inflammatory analgesics includes a whole list of drugs, including cheaper ones and those that have fewer contraindications in their description.
Paracetamol and ibuprofen are considered the safest. These substances, being part of many multicomponent drugs, relieve pain, normalize body temperature and reduce the intensity of the inflammatory process. Both paracetamol and ibuprofen are approved for use in children. The dosage form in the form of syrup allows use by children over 3 months. Ibuprofen is better for toothache and joint pain.
Paracetamol is aimed at combating headaches and muscle aches. For severe joint pain, Aertan can be replaced with Diclofenac. This active substance is sold in pharmacies. Under the same name it is found not only in the form of tablets, but also in the form of ointments, patches and ampoules for intramuscular administration. The extended-release formula of the tablets allows you to take one dose, which will relieve severe pain for 24 hours.
What is Aertal ointment for?
Ointment is a form for topical use. It is applied to damaged joints or areas of the body. Indications for use are bruises, sprains, dislocations, torticollis, or shooting sharp pain in the lower back.
The ointment is applied in a small amount to the sore spot and thoroughly rubbed into the tissue with massaging movements. Once in the body, the drug is absorbed into the blood, from where it is distributed throughout the body. As additional components, the ointment contains liquid paraffin and wax, which make its consistency soft and elastic.
Note!
Description of the drug Airtal por. d/oral. susp. 100 mg package No. 20 on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
