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Manufacturers: Biosynthesis
Active ingredients
- Levorin
Disease class
- Changes in skin structure
- Carriage of the causative agent of another infectious disease
- Candidal stomatitis
- Candidiasis of the skin and nails
- Candidiasis of the vulva and vagina (N77.1*)
- Candidiasis of other localizations
- Cystitis
- Urethritis and urethral syndrome
- Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
Clinical and pharmacological group
- Antifungal antibiotics
Pharmacological action
- Antifungal
- Fungicidal
Pharmacological group
- Antifungal agents
When is Triazavirin indicated?
Triazavirin is an antiviral drug. It was developed by institutes of two academies of sciences, RAS and RAMS. Chupakhin O.N., Kiselev O.I., Charushin V.N. worked on the medicine. The product has undergone clinical trials in 11 large accredited clinical centers. The registration certificate was issued in 2014.
The drug belongs to the azoloazine class. It is the only drug from this group. The active component of the drug is riamilovir, which directly fights viral agents.
Triazavirin is indicated for the treatment and prevention of respiratory diseases.
The drug is effective for:
- Flu (H3N2, H5N1, H1N1, H5N2, H9N2);
- Parainfluenza;
- Corey;
- Respiratory sensitial virus;
- Dengue fever, West Nile fever;
- Tick-borne encephalitis.
The product can be used for preventive and therapeutic purposes for COVID 19.
The medication is indicated only for adults. It is not used in pediatric practice due to insufficient evidence base.
special instructions
In this section you can find useful information.
Driving
The medicine may affect the driver while driving.
Pregnancy
During pregnancy, you should refrain from using this drug. During pregnancy, it is highly undesirable to take Levolin. This is due to the fact that the active substance can have a detrimental effect on the fetus.
It is also not recommended to take this drug while breastfeeding.
Admission in childhood
This drug can be taken from 2 years of age.
Use for kidney problems
Taking the drug is contraindicated if kidney function is damaged.
Use for liver dysfunction
Taking the medication is contraindicated if the liver function is impaired.
Release from pharmacy
Only by prescription from a doctor.
Medicine and alcohol
Taking medication and alcohol are two incompatible things.
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How is Triazavirin good for COVID-19?
According to the mechanism of action, the drug is active against RNA viruses. The COVID-19 genome consists of a single strand of RNA.
The drug is recommended for use for preventive purposes. It allows you to stop the proliferation of microorganisms that have penetrated the host cells. The medication is especially recommended for people who are in contact with patients with COVID-19 (relatives of coronavirus patients, doctors, nurses, etc.).
Triazavirin for moderate coronavirus can be used as part of complex therapy. The drug reduces the severity of symptoms and shortens the duration of therapy. Can be used as monotherapy for mild forms of coronavirus infection.
Storage
The drug Levorin must be placed in a room where the temperature is from 0 to 5 degrees. In addition, this room should be dark and dry. The room should also be cool (the drug is usually stored in the refrigerator).
If these conditions are met, Levorin can be taken for two years. After the expiration date, further use of the medicine is strictly prohibited. The medicinal product must be disposed of by placing it in the trash.
Side effects
Like any medicine, Triazavirin can have unwanted effects. List of consequences of use:
- eosinophilia;
- allergic reaction (rashes on the skin);
- headache;
- dyspepsia (thin stool, vomiting, nausea, bloating, gastralgia, dry oral mucosa);
- the appearance of red blood cells, bacteria, epithelial cells in the urine;
- increased levels of liver enzymes (ALT, AST).
- impotence.
If symptoms appear and intensify, you should consult a doctor to adjust your therapy. In case of an overdose, severe abdominal pain, dyspepsia, vomiting, and nausea occur.
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** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use Levorin, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.
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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Levorin is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!
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Similar products
The drug has non-structural analogues. List of similar medications:
- Anaferon - the medicine contains antibodies to human interferon gamma, which increase the overall immune status, is produced in the form of tablets, and is inferior in effectiveness to Triazavirin;
- Arbidol - produced in tablet forms or powder for making a suspension, contains umifenovir;
- Viferon - available in rectal suppositories, is highly effective against viral infections, can be used at any stage of the disease, is relatively safe; used in pediatric practice, including neonatology;
- Kagocel is an interferon inducer that stimulates the synthesis of its own interferons.
Triazavirin or Arbidol - which is better?
There is a lot of controversy surrounding these two drugs. The mechanism of action of drugs is aimed at preventing the proliferation of viral agents. Triazavirin fights viruses more effectively, unlike Arbidol. The disadvantage of riamilovir is:
- Lack of children's uniform;
- Toxicity of the drug during simultaneous use with purine analogues;
- There is a load on the liver and kidneys;
- Insufficient research has been conducted regarding the effectiveness and possible adverse effects.
Triazavirin is a relatively new antiviral drug that is currently still under study. Today it is recommended for use against coronavirus infection, all strains of influenza viruses, tick-borne encephalitis and other pathogens. The medicine copes well with infections, but has a number of side effects. The drug is also prohibited for children, pregnant women, lactating women, and patients with liver and kidney pathologies. These restrictions significantly narrow the range of its use, because older people, children, and patients with chronic diseases are more susceptible to viral infections.
Levorin
Inside. For gastrointestinal candidiasis and intestinal candidiasis, adults are prescribed 500 thousand units 2-4 times a day for 10-12 days. Children under 2 years old - 25-30 thousand units/kg/day, 2-6 years old - 20-25 thousand units/kg/day, over 6 years old - 200-250 thousand units 2-4 times a day day.
In the form of a suspension, it is prescribed at the rate of: 5 ml of suspension contains 100 thousand units, 3 drops - 2 thousand units (cooled boiled water is added to the contents of the bottle with powder for the suspension to the mark, the mixture is mixed, and shaken before use). For children. A suspension is prepared from the granules using a measuring spoon, which is filled to the bottom line (contains 1 g - 125 thousand units of the drug). To obtain a suspension for children under 1 year old, add 1 g of granules to 5 teaspoons of chilled boiled water, mix until a homogeneous suspension is obtained and give 25 thousand units/kg (1 teaspoon) 3 times a day. Children from 1 year to 2 years - 125 thousand units/kg (add 1 g of granules to 1 teaspoon of water), from 2 to 6 years - 250 thousand units/kg (2 g of granules), from 6 years and older — 375 thousand units/kg (3 g granules) 3 times a day. The course of treatment is 7-14 days, if necessary repeated after 5-7 days (under the control of a blood test). In case of nausea or vomiting, the drug is taken after meals.
For prostate hypertrophy, in the first 2 weeks, 500 thousand units are prescribed 3 times a day, then 500 thousand units 4 times a day. The course of treatment is 3 months. After 10-15 days, the course of treatment is repeated.
Locally. In the form of buccal tablets, which dissolve in the mouth within 10-15 minutes, 500 thousand units are prescribed 2-4 times a day; children 3-10 years old - 125 thousand units 3-4 times a day, 10-15 years old - 250 thousand units 2-4 times a day. The course of treatment is 7-14 days; if necessary, repeat after 5-7 days (under the control of a blood test).
In the form of an aqueous suspension (powder for preparing a solution for topical use) in a dilution of 1:500, it is prescribed for rinsing the mouth 2-3 times a day for 15-20 days. The suspension should not enter the respiratory system. In the form of the same suspension, the drug is used for wetting tampons in the treatment of diseases of the mucous membranes of the genital organs in women; the course of treatment is 15-20 days.
Vaginal tablets are inserted into the vagina after douching with a 0.5-1% sodium bicarbonate solution and drying with a cotton-gauze swab. The tablets are first moistened with distilled or boiled water and 250-500 thousand units are administered 2 times a day into the area of the posterior fornix. The course of treatment is 14 days. If necessary, a repeat course is given after 2-3 weeks (during the period between menstruation).
The ointment is applied to the affected areas 1-2 times a day for 10-15 days.
Reviews
Reviews about this medicine are usually positive. This is due to the high effectiveness of the product. In addition, among the positive reviews, people note the convenient method of administration. The drug also has a low cost, which does not put a strain on citizens’ pockets. On the forums you can find reviews not only from patients, but also from specialists who are aware of the peculiarities of taking the medicine.
Doctors note that in 90% of cases the drug has the expected effect. You can also find neutral reviews from specialists on the Internet. Doctors note the lack of effect due to improper use of the drug. The drug Levorin has a number of negative aspects, among which it is noted that the drug is quite difficult to get at the pharmacy, as well as the presence of a large number of contraindications.
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Price
To clarify the price, you need to contact a specific pharmacy or online store. The instructions provide an approximate cost.
In Russia and Ukraine the price will differ significantly. This is due to the exchange rate and currency.
Russia
For the drug Levorin you will have to pay up to 129 rubles.
Ukraine
The medicine Levorin costs on average 59 hryvnia.
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