Compound
One chewable Maalox tablet contains 400 mg of aluminum hydroxide and 400 mg of magnesium hydroxide . Additional substances: sorbitol , starch with sucrose, magnesium stearate, mannitol, sodium saccharinate, mint flavor, sucrose.
1 sachet of suspension (15 ml) of Maalox contains 525 mg of aluminum hydroxide and 600 mg of magnesium hydroxide . Additional substances: citric acid monohydrate, hydrochloric acid, mannitol, peppermint oil, propyl parahydroxybenzoate, methyl parahydroxybenzoate, hydrogen peroxide, sorbitol, sodium saccharinate, water.
A 250 ml suspension of the drug Maalox (bottle) contains 3.5 grams of aluminum hydroxide and 4 grams of magnesium hydroxide . Additional substances: citric acid monohydrate, hydrochloric acid, mannitol, peppermint oil, propyl parahydroxybenzoate, methyl parahydroxybenzoate, hydrogen peroxide, sorbitol, sodium saccharinate, water.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
An antacid that neutralizes unbound hydrochloric acid in the stomach does not provoke its secondary hypersecretion. Due to a decrease in the acidity of gastric juice, when using the drug Maalox, the peptic activity of the secreted gastric juice decreases. It has adsorbing and enveloping properties that weaken the effect of damaging agents on the mucous membranes of the stomach and esophagus.
Pharmacokinetics
The active substances of the drug are considered local antacids, which are almost not absorbed when taken orally in the doses below and do not have general effects.
Maalox for poisoning
When intoxicated, the functioning of the digestive system is disrupted.
Maalox helps quickly remove toxic substances. It is recommended to take the medicine in any form immediately after diagnosing the first unpleasant symptoms. The drug forms a protective film on the mucous membrane, which speeds up the recovery process after poisoning. Maalox also reduces acidity in the stomach and helps get rid of negative symptoms.
In case of alcohol poisoning, Maalox controls the production of bile and normalizes the volume of hydrochloric acid in the stomach. Thanks to the adsorbing effect, it eliminates toxic substances - remnants of ethanol breakdown.
The suspension has an antacid and enveloping effect, which helps alleviate a person’s condition after drinking alcohol and protects the esophageal mucosa from the harmful effects of poison. In case of alcohol poisoning, take it according to the instructions.
It is recommended to remember that Maalox alone will not cope with the signs of poisoning. The drug is used in combination with other medications prescribed by a doctor. Maintaining proper nutrition and water regime will help enhance the effect of the product.
We recommend: How to restore intestinal microflora after poisoning: methods
Indications for use of Maalox
What are Maalox tablets and suspension for?
- exacerbation of peptic ulcer ;
- acute and chronic gastroduodenitis in the acute phase with normal or enhanced secretory function;
- diaphragmatic hernia , reflux esophagitis ;
- dyspeptic symptoms, including with excessive intake of coffee, nicotine, ethanol, medications, errors in diet (for suspension);
- pain or discomfort in the upper third of the abdomen, including with excessive intake of coffee, nicotine, ethanol, medications, errors in diet (for suspension).
Contraindications
- severe renal failure ;
- hypersensitivity to the components of the drug;
- fructose intolerance;
- hypophosphatemia;
- glucose-galactose malabsorption syndrome , sucrase or isomaltase deficiency (chewable tablets);
- intolerance to maltitol (chewable tablets);
- age less than 15 years.
It is necessary to use the medicine with caution in patients on hemodialysis with porphyria, during pregnancy, Alzheimer's disease , and diabetes mellitus (chewable tablets).
Side effects when taken
Maalox is a medicine and has some contraindications for which its use is not recommended. There are several pathological conditions of the body.
It is not allowed to use:
- age up to fifteen years;
- severe kidney failure;
- reduced phosphate content;
- intolerance to fructose and maltitol;
- excessive sensitivity to other ingredients of the drug;
- Alzheimer's disease;
- with caution in case of porphyria and pregnant women.
It is permissible to use the medication during lactation. It is not recommended to give tablets to patients with diabetes due to the presence of sugar in them. If used incorrectly, the development of side effects is possible.
What happens:
- allergic manifestations on the skin;
- anaphylactic and angioedema shock;
- disruption of intestinal function in the form of constipation or diarrhea;
- complication of Alzheimer's disease;
- decreased manifestation of reflexes;
- decrease in pressure;
- decreased bone strength due to insufficient mineralization of bone tissue;
- diseases of bones and joints;
- accumulation of calcium in the kidneys;
- a strong excess of the norm of magnesium, aluminum and phosphates in the body.
We recommend: Smecta for stomach pain and poisoning
In elderly patients, incorrect dosing of Maalox can lead to exacerbation of intestinal obstruction and the development of serious obstruction.
Side effects
- Reactions from the immune system: anaphylactic reactions, urticaria , itching , angioedema .
- Digestive reactions: diarrhea , constipation .
- Metabolic reactions: hyperaluminemia , hypermagnesemia , hypophosphatemia (with prolonged therapy or taken in large doses, with low concentrations of phosphates in food), which can lead to increased bone resorption, osteomalacia , hypercalciuria .
Instructions for use of Maalox (Method and dosage)
Maalox tablets, instructions for use
It is recommended to dissolve or chew the tablets. Persons over 15 years of age are prescribed to take 1-2 tablets three to four times a day at intervals of 1-2 hours after meals and before bedtime.
When treating reflux esophagitis, the medicine is taken within a short time interval after eating. The maximum permitted frequency of administration is 6 times a day. It is strictly forbidden to take more than 12 tablets per day.
The duration of treatment should not last more than 3 months. For a single use (after errors in the diet), use 1-2 tablets.
Maalox suspension, instructions for use
Suspension in bags
Before use, the suspension in the bag must be homogenized by kneading it well. The contents are taken without dissolution, 1 sachet (15 ml) 2 hours after meals and before bedtime, as well as when abdominal pain or heartburn develops. The daily dosage should not be more than 6 sachets.
When treating reflux esophagitis, the medicine is taken half an hour after meals, and when treating peptic ulcers - half an hour before meals.
The duration of treatment should not be more than 3 months. For discomfort after eating spicy, fatty or fried foods, take 15 ml of suspension once.
Suspension in bottles
The instructions describe how to take the suspension: shake the bottle before taking. Usually it is prescribed to take 1 tablespoon (15 ml) of the drug 3-4 times a day, 1-2 hours after meals and before bedtime. The dosage should not be more than 6 tablespoons per day.
When treating reflux esophagitis, Maalox is taken 30 minutes after eating.
The duration of treatment should not be more than 3 months. For discomfort after eating spicy, fatty or fried foods, take 15 ml of suspension once.
In persons with impaired renal function, the use of the drug in high dosages or for long periods of time should be avoided.
How can you overdose on Maalox?
If the rules of use are not followed, Maalox can cause poisoning. Taking the medication in high doses causes the patient to experience diarrhea, abdominal pain, nausea and vomiting, and loss of fluid.
In people at risk, it is possible that serious disorders of intestinal function may develop. In serious situations, encephalopathy, increased calcium levels in the urine, and abnormalities in the nervous system may occur.
Treatment of an overdose of Maalox is carried out in the hospital. After the examination, suitable treatment methods are selected.
Therapy:
- The main elements - magnesium and aluminum - are removed from the body through urine.
- The patient is advised to drink plenty of fluids and forceful diuresis.
- When diagnosing kidney failure, it is possible that hemodialysis or peritoneal dialysis will be required.
The duration of therapy depends on the degree of poisoning. If therapy is started on time, recovery occurs in a short time.
Interaction
When used together with Quinidine, an increase in its content in the blood and even an overdose of Quinidine are possible.
When used together with the drug Maalox, absorption from the intestine of the following drugs is reduced: Propranolol , H2-histamine receptor blockers, Atenolol , Cefdinir , Metoprolol , Cefpodoxime , prostacyclins , chloroquine , Digoxin , Diflunisal , Ethambutol , bisphosphonates, Isoniazid , sodium fluoride , fluoroquine lonov, Prednisolone, Indomethacin , Dexamethasone , Ketoconazole , phenothiazine neuroleptics, lincosamides, Penicillamine , iron salts, Rosuvastatin , levothyroxine sodium. By maintaining a 2-hour break between the use of these drugs and Maalox and a 4-hour break between the use of fluoroquinolones and Maalox, unwanted interactions between these drugs can be avoided.
When taking Maalox with polystyrene sulfonate , there is a risk of metabolic alkalosis (in people with renal failure) and intestinal obstruction.
Interaction with other drugs
Maalox can affect other medications - enhance or weaken their effect. Therefore, it is recommended to take it two hours before or after other medications.
When using fluoroquinolones in treatment, the interval between the use of Maalox and the medication should not be less than four hours. What else should you pay attention to?
Use together with Quinidine is fraught with exceeding the level of the compound and causing an overdose of Quinidine. When used with certain medications, the effectiveness of the latter decreases.
Medicines:
- aspirin;
- fluoroquinolone;
- sodium fluoride;
- propranolol;
- diflunisal;
- digoxin;
- atenolol;
- ethambutol;
- isoniazid;
- ketoconazole;
- indomethacin;
- lansoprozole;
- levothyroxine;
- fexofenadine.
Maalox reduces the effect of antibiotics containing tetracycline, glucocorticosteroids, and biological additives containing phosphorus. Concomitant use with iron compounds, antipsychotics and antihistamines is not recommended.
Maalox can be purchased at a pharmacy without a prescription. However, taking it requires care and adherence to instructions in order to avoid unpleasant consequences.
special instructions
If, during drug therapy, symptoms from the digestive system do not stop within 10 days, then it is necessary to clarify the diagnosis and change the treatment regimen.
The drug is sold without a prescription, but before taking it during pregnancy , lactation , as well as in adolescents and patients with renal failure, it is recommended to consult with your doctor.
Aluminum hydroxide with a low phosphate content in food can lead to phosphorus deficiency in the body.
Special instructions for the use of the drug Maalox
Patients should be advised to seek medical help in the following cases:
- with weight loss;
- difficulty swallowing or a constant feeling of discomfort in the abdomen;
- digestive disorders that appeared for the first time, or changes in the course of existing digestive disorders;
- renal failure.
Since Maalox contains sorbitol, it is contraindicated in patients with fructose intolerance. Precautionary measures for use. When treating patients with renal failure or those on constant hemodialysis, the presence of aluminum in the drug must be taken into account (there is a risk of encephalopathy). If digestive disorders persist after 10 days of treatment or their course worsens, you need to find out the cause of their occurrence and reconsider the prescribed treatment. In cases where treatment is carried out with other drugs that are administered orally, Maalox should be taken 2 hours before or 2 hours after using the drugs listed in the “Interaction” section. Use during pregnancy and lactation. There are no reliable data regarding teratogenic effects in animals. No specific teratogenic or fetotoxic effects have been observed in humans. However, long-term follow-up data from pregnant women who used the drug are not sufficient to exclude any risk. Therefore, during pregnancy, this drug should be used only when the benefit to the mother outweighs the risk to the fetus. Maalox contains aluminum and magnesium ions, which can affect the tone of the gastrointestinal tract, which must be taken into account:
- magnesium hydroxide salts can cause diarrhea;
- Aluminum salts can worsen constipation, which is quite common during pregnancy.
Maalox should not be taken for a long time or in large doses. During treatment with Maalox, you can continue breastfeeding. Children . There is no experience using the drug in children under 15 years of age. The ability to influence the reaction rate when driving a vehicle or working with other mechanisms. Does not affect.
Analogues of Maalox
Level 4 ATC code matches:
Gastracid
Relzer
Rennie
Gaviscon Forte
Gastal
- Ajiflux
- Alumag
- Almagel
- Almol
- Almagel Neo
- Altacid
- Anacid Forte
- Palmagel
- Maalox Mini
- Gastracid
- Maalukol
- Rivolox
- Phosphalugel
The price of Maalox analogues in identical release forms is usually lower than the price of the drug being described.
Which is better: Almagel or Maalox?
The drugs belong to the same pharmacological group and are analogues. The active substances in these drugs are contained in different ratios. In this regard, Almagel constipation , and the effect of Maalox is almost twice as long.
Which is better: Maalox or Phosphalugel?
Of the two drugs, it is preferable to choose Phosphalugel (especially for the elderly and pregnant women), because it does not contribute to excessive evacuation of phosphates from the body (mainly from the bones).
Maalox price, where to buy
The price of Maalox in tablets No. 20 in Russia is about 250 rubles. The price of Maalox suspension 250 ml in bottles is approximately 350 rubles.
In Ukraine, the average cost of tablets in the specified release form is about 130 hryvnia, and the gel suspension is approximately the same price.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Maalox Susp.
250ml Sanofi S.p.A RUB 377 order - Maalox tab. chewing sugar free 10pcs Sanofi S.p.A
RUB 157 order
- Maalox chewable tablets. 20 pcs. Sanofi S.p.A.
RUB 264 order
- Maalox sachet oral suspension 15ml 30pcsPharmatis for Laboratoire Theraplix
RUR 927 order
Pharmacy Dialogue
- Maalox for heartburn and stomach pain suspension 250mlSanofi-Aventis
425 rub. order
- Maalox antacid for heartburn and stomach pain, sugar-free tablets No. 20Sanofi-Aventis
RUB 259 order
- Maalox antacid for heartburn and stomach pain, sugar-free tablets No. 10Sanofi SpA
RUB 165 order
- Maalox sachet No. 1Aventis/Pharmatis
32 RUR order
- Maalox for heartburn and stomach pain suspension packages 15ml No. 6Pharmatis
RUB 247 order
show more
Pharmacy24
- Maalox 15 ml No. 30 suspension Pharmatis, France
301 UAH. order - Maalox No. 40 tablets Sanofi-Aventis S.p.A.,Italy/Sanofi S.P.A.Italy
117 UAH. order
- Maalox mini 4.3 ml No. 20 lemon suspension Sanofi-Aventis S.p.A.,Italy/Sanofi S.P.A.Italy
155 UAH order
- Maalox 250 ml suspension E. Nattermann & Sayi GmbH, Germany
129 UAH order
PaniPharmacy
- Maalox liquid Maalox suspension. package 15ml No. 30 France, Pharmatis
318 UAH. order
- Maalox mini liquid Maalox mini suspension. d/peror. approx 25mEq/4.3ml pack No. 20 Germany, Nattermann
162 UAH order
- Maalox liquid Maalox suspension. 250ml Germany, Nattermann
131 UAH order
- Maalox tablets Maalox tablets No. 40 France, Aventis Pharma Specialite
138 UAH order
- Maalox tablets Maalox tablets. chewing No. 20 Italy, Sanofi
78 UAH order
show more
How to take Maalox mini
The medication in any form is intended for oral administration. It should be taken at least an hour after meals. If sharp, unbearable pain occurs, the medicine can be taken immediately.
Before taking the suspension in the bottle, you need to shake it well. If we are talking about a suspension in a bag, then before opening, you need to knead the contents well. Does not need to be dissolved in water.
Teenagers from 15 years of age and adults can use 1 tbsp. l. suspension three times a day. It is permissible to take no more than 90 ml per day. Depending on the problem, the dose may vary.
If you take the drug in tablet form, then a single dose should not exceed two tablets. You should drink no more than 4 times a day. They are dissolved or chewed; there is no need to drink water.
During prolonged use of the medicine, you need to monitor your well-being. If after 10 days of the treatment course there is no noticeable improvement or the condition has become even worse, then you should seek the help of a specialist.
