Matarin plus ointment is considered an effective remedy in the treatment of injuries and various pathologies. It has a pronounced analgesic effect and relieves inflammation. The drug has a yellowish tint and a uniform consistency. The product is used to relieve pain during the development of various inflammatory and degenerative joint diseases. The ointment also alleviates the condition of rheumatic lesions.
Compound
Cream for external use | 1 g |
active substance: | |
meloxicam | 30 mg |
capsicum fruit tincture | 100 mg |
excipients: dimethyl sulfoxide; coriander oil; lavender oil; liquid paraffin; propylene glycol; stearic acid 50; distilled monoglycerides ( Dimodan HP ); emulsion wax; glycerol; poloxamer (emuxol 268); carbomer; sodium hydroxide; imidomerea; water |
Mataren plus cream for external use, 50g
Registration Certificate Holder
NIZHFARM (Russia)
Dosage form
Medicine - Mataren® Plus (Mataren Plus)
Description
Cream for external use
from light yellow to dark yellow; a reddish-brown tint is allowed.
1 g
meloxicam 30 mg tincture of capsicum fruit 100 mg
Excipients
: dimethyl sulfoxide, coriander oil, lavender oil, liquid paraffin, propylene glycol, stearic acid 50, distilled monoglycerides (Dimodan HP), emulsion wax, glycerol, poloxamer (emuxol-268), carbomer, sodium hydroxide, imidourea, water.
10 g - aluminum tubes (1) - cardboard packs. 15 g - aluminum tubes (1) - cardboard packs. 20 g - aluminum tubes (1) - cardboard packs. 30 g - aluminum tubes (1) - cardboard packs. 40 g - aluminum tubes (1) - cardboard packs. 50 g - aluminum tubes (1) - cardboard packs. 100 g - aluminum tubes (1) - cardboard packs. 10 g - polyethylene tubes (1) - cardboard packs. 15 g - polyethylene tubes (1) - cardboard packs. 20 g - polyethylene tubes (1) - cardboard packs. 30 g - polyethylene tubes (1) - cardboard packs. 40 g - polyethylene tubes (1) - cardboard packs. 50 g - polyethylene tubes (1) - cardboard packs. 100 g - polyethylene tubes (1) - cardboard packs.
Indications
- inflammatory and degenerative diseases of the musculoskeletal system;
- rheumatic lesions of soft tissues;
- pain syndrome: bursitis, tendinitis, lumbago, sciatica, neuralgia, myalgia, arthralgia, radiculitis, post-traumatic pain syndrome (traumatic bruises, dislocations, sprains, muscles and tendons, muscle ruptures without compromising the integrity of the skin), pain in muscles and joints caused by heavy physical activity.
Contraindications for use
- hypersensitivity to the components of the drug;
- children under 12 years of age;
- violations of the integrity of the skin and inflammatory skin diseases at the site of intended application of the drug;
Carefully
In cases of impaired renal and liver function, severe gastrointestinal pathology (peptic ulcer of the stomach and duodenum in the acute phase), severe pathology of the blood system, in childhood from 12 to 18 years.
The patient should consult a doctor before combining Mataren® Plus cream with other NSAIDs, as well as if it is necessary to use the drug for more than 10 days.
pharmachologic effect
Mataren® Plus has an anti-inflammatory, analgesic, anti-edematous effect, and can cause mild local hyperemia of the skin without causing a pronounced irritant effect on the skin.
Mataren® Plus reduces pain in the joints (including the joints of the spine) and in the muscles at rest and during movement, helps to increase the range of motion of the joints (in the area where the cream is applied). Reduces morning stiffness and swelling of joints.
Meloxicam selectively inhibits cyclooxygenase 2, disrupts the metabolism of arachidonic acid, and reduces the amount of prostaglandins (mediators of pain and inflammation) at the site of inflammation.
Capsicum tincture contains capsaicin, which has an irritating effect on sensitive skin receptors, which leads to a local analgesic effect, improved blood circulation in the skin and subcutaneous tissue, as well as a warming effect. Improving local blood flow is accompanied by increased blood circulation in the underlying tissues, which helps remove the substrate of inflammation from the pathological focus.
When combined, the active components of Mataren® Plus cream have a greater effect due to synergy, compared to the individual effect of each of these components.
Thanks to the optimal combination of cream components, there is a mutual enhancement of their analgesic and anti-inflammatory effects.
Drug interactions
Currently, there is no data on the interaction of Mataren® Plus with other drugs.
Dosage regimen
Externally. Lightly rub in a strip of cream 1 to 5 cm long, frequency of use is 1-3 times a day. The amount of cream and frequency of application may vary depending on the area of application and individual reaction to the cream. To enhance the effect, you can apply a dry warming bandage.
Overdose
There are no known cases of overdose of Mataren® Plus.
Side effect
The side effects that occur depend on individual sensitivity.
Allergic reactions
from the skin (itching, skin rash), peeling of the skin, hyperemia are possible
If any side effects occur, the patient should stop using the cream and consult a doctor.
special instructions
Avoid contact of the drug with damaged skin, eyes and mucous membranes. If Mataren® Plus cream gets on these areas, it should be removed using a cotton swab soaked in Vaseline or vegetable oil.
After using the drug, you must wash your hands thoroughly.
Effect on the ability to drive vehicles and machinery.
The use of the drug does not affect the ability to drive vehicles and machinery.
Storage conditions
The drug should be stored out of the reach of children at a temperature not exceeding 25°C.
Best before date
Shelf life: 2 years.
Use during pregnancy and breastfeeding
Restrictions during pregnancy - Contraindicated. Restrictions during breastfeeding - Contraindicated. Use of the drug is contraindicated during pregnancy and lactation.
Use for renal impairment
Restrictions for impaired renal function - With caution.
Carefully _
the drug should be prescribed for impaired renal function.
Use for liver dysfunction
Restrictions for liver dysfunction - With caution.
Carefully _
the drug should be prescribed for liver dysfunction.
Use in children
Restrictions for children - Contraindicated.
Contraindicated in children under 12 years of age.
with
caution
in adolescence from 12 to 18 years.
Terms of sale
The drug is available without a prescription.
Contacts for inquiries
STADA (Russia)
603950 Nizhny Novgorod st. Salganskaya, 7 Tel. Fax E-mail
Pharmacodynamics
Mataren® Plus has anti-inflammatory, analgesic, and anti-edematous effects. May cause mild local hyperemia of the skin without causing a pronounced irritant effect on the skin.
Mataren® Plus reduces pain in the joints (including the joints of the spine) and muscles at rest and during movement, helps to increase the range of motion of the joints (in the area where the cream is applied). Reduces morning stiffness and swelling of joints. Meloxicam selectively inhibits COX-2, disrupts the metabolism of arachidonic acid, and reduces the amount of PGs (mediators of pain and inflammation) at the site of inflammation.
Capsicum tincture contains capsaicin, which has an irritating effect on sensitive skin receptors, which leads to a local analgesic effect and improved blood circulation in the skin and subcutaneous tissue. Improving local blood flow is accompanied by increased blood circulation in the underlying tissues, which helps remove the substrate of inflammation from the pathological focus.
When combined, meloxicam and capsaicin have a greater effect due to synergism compared to the individual effect of each of these components. Thanks to the optimal combination of components, Mataren® Plus has an enhanced analgesic and anti-inflammatory effect.
Peculiarities
Mataren plus ointment effectively relieves pain in muscles and joints caused by various reasons. It belongs to the group of combined non-steroidal anti-inflammatory drugs. The ointment reduces the intensity of pain in a short time and allows you to stabilize the condition. It is in demand for injuries, as well as for the treatment of various diseases. systems.
When using the ointment at the initial stage of treatment, it is possible to prevent the pain syndrome from becoming chronic. This particularly applies to cases where joint stiffness occurs in the morning. When using the product, you can stop taking other painkillers in the form of injections and tablets.
Active components in the ointment:
- Meloxicam. This substance is distinguished by its ability to relieve inflammation and pain. It provides quick results and is able to relieve pain in approximately 30 minutes.
- Capsicum tincture. The capsaicin contained in its composition has a local irritating and distracting effect.
The combination of these components in the ointment enhances the effectiveness of the drug in relieving inflammation and pain relief. When using the drug, it is possible to quickly stabilize the condition and return to normal life.
Contraindications
hypersensitivity to the components of the drug;
violations of the integrity of the skin and inflammatory skin diseases at the site of intended application;
children's age (up to 12 years).
Carefully:
impaired renal and liver function; severe gastrointestinal pathology (peptic ulcer of the stomach and duodenum in the acute phase); severe pathology of the blood system; children's age (from 12 to 18 years).
You should consult your doctor before using Mataren® Plus cream together with other NSAIDs, as well as if you need to use the drug for more than 10 days.
When is it prescribed?
Mataren ointment, the price of which is affordable, has a wide range of uses. It increases the effectiveness of treatment of various diseases of the musculoskeletal system. In particular, the drug is indicated for complex therapy:
- Arthritis. These diseases are characterized by inflammation of the joints and in the acute stage are accompanied by severe pain.
- Ankylosing spondylitis. The first symptoms of the disease are associated with the appearance of back pain. As the disease progresses, spinal mobility is impaired.
- Osteoarthrosis. The disease is characterized by the occurrence of degenerative disorders in the joints and periarticular tissues.
- Rheumatism. The disease develops against the background of infection and is manifested by damage to the joints, heart and central nervous system. Its symptoms are acute pain and swelling in large joints without deformation.
An ointment is prescribed for rheumatic lesions of soft tissues. Most often, the pathological condition occurs with joint damage caused by infection, tumors and other factors.
The drug is indicated for relieving pain of various etiologies. It allows you to stabilize the condition in many pathological conditions accompanied by pain in the joints and muscle tissues, etc. The ointment is indicated for relieving post-traumatic pain syndrome in the postoperative period. The drug is prescribed to relieve muscle pain caused by physical activity.
special instructions
Avoid contact of the drug with damaged skin, eyes and mucous membranes. If Mataren® Plus cream gets on these areas, it should be removed using a cotton swab soaked in Vaseline or vegetable oil.
After using the drug, you must wash your hands thoroughly.
Influence on the ability to control means and mechanisms.
The use of the drug does not affect the ability to drive vehicles or machinery.
Usage
Matarin Plus ointment is intended for external use only. A strip of the product up to 5 cm long is applied to the area of the skin where pain is felt. After this, the ointment is rubbed into the skin with light massage movements. It is permissible to carry out the procedure up to 3 times a day.
The dosage of the drug and the frequency of its use can be changed in accordance with the doctor’s recommendations. This may be related to the size of the damaged area and the severity of symptoms. The effect of using the ointment can be enhanced by using a dry warming bandage.
The shelf life of Mataren plus ointment is 2 years. Once completed, the product cannot be used. The drug should be stored out of the reach of children at a temperature not exceeding 25°C. Despite the fact that Mataren Plus ointment can be bought without a prescription, its use is allowed only if there are indications confirmed by a doctor.