Has restrictions during pregnancy
Has restrictions when breastfeeding
Has restrictions for children
Allowed for older people
Has limitations for liver problems
Has limitations for kidney problems
Poor nutrition, overeating, and frequent dry snacks have become commonplace in the life of a modern person. At the first manifestation of stomach discomfort, it is recommended to use Mezim. This medicine, popular among consumers, improves the quality of the intestines and pancreas. It contains pancreatin of animal origin, which consists of lipase, amylase and protease.
In pharmacies, Mezim Forte is presented in various dosages - 3500, 10000 or 20000 mg of the active substance. The drug is produced in the form of pink tablets, enteric-coated.
Indications for use of the drug are:
- chronic diseases of the gastrointestinal tract;
- before conducting studies of the abdominal area (ultrasound, x-ray);
- functional disorders of the gastrointestinal tract due to lack of production of pancreatic enzymes;
- postoperative period characterized by digestive disorders;
- to improve the functioning of the gastrointestinal tract.
General information about the drug
The drug is prescribed to children from 3 years of age. During pregnancy and lactation, Mezim Forte is used after consulting a doctor.
If the desired drug is not available in the pharmacy or is contraindicated for some reason, it becomes necessary to replace it. There are a number of analogues in pharmacies that are not inferior to Mezim in their composition, and sometimes turn out to be more accessible.
Contraindications for use
Do not use the drug for:
- acute form of pancreatitis;
- intolerance to the components of the drug;
- children under 3 years of age.
According to medical research, the medication does not have a negative effect on the embryo developing in the womb and does not make breast milk harmful to the baby.
Therefore, the drug is allowed to be used by pregnant women and breastfeeding mothers, but with extreme caution, under the strict supervision of a doctor.
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Instructions for use for adults and children
The dosage is determined by the doctor individually for each patient and is determined by the intensity of the manifestation of the pathology of the digestive system.
The standard dose for an adult patient is 2 tablets before meals. The tablets should be swallowed without chewing and washed down with water. The dose for enzyme replacement therapy can reach 4 tablets. The dosage for children is selected exclusively by a medical specialist.
The therapeutic course can last from two days to several months. The duration of treatment is determined by the severity of disorders of the digestive tract. In certain cases, therapy is delayed for several years.
The drug does not affect concentration, so it can be taken by people driving a car or other vehicle or operating a complex mechanism.
Foreign analogues
When choosing a medicine, many consumers pay attention to the country in which it is produced. Among foreign drugs there are also those that are substitutes for Mezim.
Pangrol
The drug is manufactured in Italy or Germany. It comes in the form of hard enteric capsules containing pancreatin. It is used to optimize the functioning of the digestive organs, combat the symptoms of achylia, indigestion, long-term pancreatitis, gastritis, enterocolitis. Usually take 2-4 capsules after meals and wash down with 100 ml of water.
Minitablets Pangrol
The quantity and duration of treatment is prescribed by a specialist. If a patient is found to be susceptible to the composition of the drug and/or has acute pancreatitis, taking the medication is not recommended. The drug is prescribed to children from the age of 6 years.
Creon
Instant capsules that contain pancreatin. Tips for use are similar to taking similar medications - prescribed for symptoms of achylia, poor digestion, gastritis, enterocolitis, inflammatory processes in the gastrointestinal tract and other disorders that are accompanied by an exocrine disorder of the gland that secretes pancreatic juice.
Mechanism of action of Creon
A single dose of the medicine should be divided: half should be taken before meals, and the remaining contents of the capsule should be taken during meals. If the patient has acute inflammation of the pancreas in the early stages and hypersensitivity to the composition of the drug, then the use of Creon is contraindicated. The drug is manufactured in Germany.
Enzibene
Country of origin: India. The drug improves the absorption of food in the body and the excretory functions of the pancreas. Recommendations for use are identical to other drugs containing pancreatin. 1-2 tablets are taken orally before meals, whole, with a glass of water.
Considering the type of food and the severity of the digestive disorder, you can take an additional 2-4 tablets after meals.
If the patient has acute pancreatitis and is hypersensitive to the drug, Enzibene is contraindicated for use.
Festal
In addition to pancreatin, Festal tablets contain bovine bile, which is also an enzymatic substance. Made in India. Festal is prescribed for weak excretory function of the pancreas, chronic pancreatitis, to optimize food processing processes in ulcerative colitis and other disorders in the body that require the intervention of enzymatic substances.
Indications for the use of Festal
Method of administration: 1 tablet during and after meals. The duration of treatment ranges from one day to several months. The drug is prescribed only to adults. Contraindications:
- increased susceptibility to enzymes of animal origin;
- hepatitis;
- pancreatitis in the acute stage;
- intestinal obstruction.
Mezim analogues are cheaper - list with prices
Below is a list of analogues cheaper than Mezim with average prices. Of the domestic and imported substitutes, the following should be noted:
- Abomin – 145 rubles;
- Pancreatin – 40 rubles;
- Acidin-pepsin – 180 rubles;
- Enzistal – 220 rubles;
- Penzital – 120 rubles;
- Festal - 340 rubles.
There are also effective and popular substitutes that are slightly more expensive than Mezim:
- Ermital - 460 rubles;
- Enterosan – 430 rubles;
- Creon – 530 rubles;
- Micrazim – 500 rubles;
- Pangrol – 580 rubles.
Pancreatin or Mezim – which is better?
Pancreatin is the cheapest Russian analogue of Mezim. The substitute is based on the same active substance as the original. Both drugs have the same effect on the body. Both Pancreatin and Mezim begin to act approximately 30 minutes after oral administration.
Pancreatin is prescribed for difficult digestion and certain diseases of the digestive tract.
The drug can be used for disorders of the liver and gallbladder.
Children are allowed to take the analogue, but under the supervision of a medical specialist. Young children may experience constipation after taking the medication.
A cheap Russian analogue can be purchased at any pharmacy. The drug is sold in tablet and capsule form, and also in the form of dragees.
Prices for the drug and its analogues
Often, a substitute drug is selected based on price. Below is a list of Mezim analogues, which are cheaper or more expensive, but basically have a similar effect on the human body.
Drug name | Release form, quantity | Price in rubles (average) |
Mezim Forte Mezim Forte | tablets, 20 pcs. tablets, 80 pcs. | 55-75 215-300 |
Acedin-pepsin | tablets, 50 pcs. | 104 |
Unienzyme | tablets, 20 pcs. | 140 |
Panenzyme | tablets, 20 pcs. | 138 |
Fermentium | dragees, 20 pcs. | 118 |
Abomin | tablets, 20 pcs. | 210 |
Pancreatin Pancreatin forte | tablets, 20 pcs. tablets, 20 pcs. | 25-35 25-40 |
Penzital | dragees, 100 pcs. | 120-140 |
Enterosan | capsules, 20 pcs. | 428 |
Enzistal | dragees, 20 pcs. | 75-90 |
Kreazim | capsules, 20 pcs. | 115-130 |
Enzibene | capsules, 20 pcs. | 155-200 |
Creon 10000 | capsules, 20 pcs. | 195-270 |
Pangrol | capsules, 20 pcs. | 460-480 |
Festal | dragees, 100 pcs. | 365-500 |
Micrasim | capsules, 50 pcs. | 640-750 |
Festal or Mezim – which is better to buy?
If the question arises of what to replace Mezim with, then the most popular and advertised analogue can be called Festal. The substitute and the original have the same effect on the digestive organs and are practically the same in price.
Festal is an enzyme medicine sold in the form of tablets.
The enzymes included in the drug normalize digestive function, stimulate the formation of bile, and improve the absorption of proteins and carbohydrates.
The medicine, in addition to enzymes, includes cow bile, which activates the work of the liver and pancreas.
Festal is recommended for patients suffering from cystic fibrosis and chronic pancreatitis. The drug helps with weak secretory activity of the pancreas, chronic pathologies of the liver, stomach and intestinal tract.
Side effects may occur when taking the drug: diarrhea, nausea, decreased bile synthesis. In case of an overdose of the drug, hyperuricemia and perianal dermatitis develop, and the mucous membranes of the oral cavity are irritated.
It is forbidden to take Festal in case of liver failure, acute pancreatitis, hepatitis, gallstones, intestinal obstruction, jaundice, purulent lesions of the gallbladder.
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Popular Russian substitutes
For the convenience and comfort of customers, domestic pharmacists produce cheaper Russian drugs, which in their composition and medicinal properties are not inferior to Mezim.
Abomin
Dragees containing the substance abomin. It is synthesized from the stomach of young lambs and calves. Abomin improves the absorption of food in case of insufficient enzymatic activity of gastric juice. Prescribed for the following pathologies:
- gastroenteritis;
- enterocolitis;
- ahilia;
- gastritis;
- dyspepsia.
Description of Abomina
Use the drug three times a day, 1 tablet for two months. The medicine is contraindicated in patients under 14 years of age and people with abomin intolerance.
Micrasim
A Russian-made enzyme preparation improves the quality of the digestive process. The drug contains pancreatin. Doctors advise taking the drug after meals with liquid. The dosage of the medicine is prescribed by a specialist separately for each patient. This mainly depends on the age category, diet and severity of the disease.
Mechanism of action of the drug
The drug replaces the deficiency of pancreatic enzymes. It is not advisable to use Micrazim for people who are immune to the substances of the drug; other than this, there are no restrictions.
Pancreatin
The medicine has an optimal effect on the general condition of the gastrointestinal tract, improves digestion and compensates for the lack of enzyme in the pancreas. The main component of the tablets is the enzyme pancreatin, which is a natural component of the pancreas. The drug is effective for the following disorders:
- long-term forms of liver and biliary tract disease;
- digestive disorders that are caused by the inability to chew food;
- digestive disorders that are caused by the consequences of eating heavy foods;
- inflammatory processes in the gastrointestinal tract.
It is used when preparing a patient for examination of the abdominal organs: ultrasound, radiography. The spectrum of action of the drug is quite extensive. The medicine is prescribed in accordance with the specific characteristics of the patient. For children, the drug is prescribed according to the age and weight of the child. Pancreatin is undesirable for acute and long-term pancreatitis, obstructive jaundice, hepatitis, intestinal obstruction, impaired liver function, cholelithiasis.
Enterosan
It is produced in the form of capsules, which contain lyophilisate from the glands of the gastric mucosa of birds. Enterosan optimizes the absorption of food in the body, reduces the symptoms of diarrhea, and also eliminates intestinal dysfunction.
Pharmacological action of the drug
Based on the diagnosis, the specialist determines the course duration and dosage. In most cases, the medicine is taken 1-2 capsules three times a day. The main prohibition on taking the drug is hypersensitivity to its composition.
Kreazim
Kreazim is produced in capsules containing pancreatin. Most often it is used to treat:
- ahilia;
- chronic pancreatitis with insufficient pancreas function;
- chronic enterocolitis;
- digestive disorders;
- anacid and hypoacid gastritis.
The doctor prescribes the dosage and duration of treatment with the drug. Capsules are taken orally. It is recommended to take 1/3 or 1/2 dose before meals and the remainder during meals.
Experts do not recommend taking Kreazim if chronic pancreatitis worsens or if you have an individual allergic reaction to the composition of the drug.
Mezim or Creon – which is better to choose?
Creon is a high-quality but expensive German substitute for Mezim, sold in capsule form.
Recommended for chronic pathologies of the digestive tract, malignant tumors in the pancreas.
The scope of application of the German analogue is wider than that of the original drug. Creon is prescribed for:
- chronic form of pancreatitis;
- cystic fibrosis;
- cirrhosis;
- blockage of the bile ducts;
- Shwachman-Diamond syndrome;
- pancreatic oncology;
- hepatitis of cholestatic type;
- age-related impairment of enzyme activity of the digestive tract;
- pathological changes in the microflora of the small intestine;
- gastroparesis;
- duodenostasis.
The drug is also recommended for use to relieve unpleasant symptoms after surgical removal of the pancreas, gall bladder, or complete or partial excision of the stomach.
Usually the drug is normally accepted by the body of both adults and small patients. Sometimes unpleasant but not dangerous side effects occur: abdominal pain, diarrhea, nausea, excess gas formation. A minor allergic rash may appear on the skin.
Patients with acute pancreatitis who are sensitive to the active substance in the drug should not take Creon.
Is it worth buying Micrasim?
Micrazim is a high-quality substitute for Mezim, sold in capsule form, based on pancreatin.
According to the principle of operation, the analogue and the original are practically the same.
However, Mikrazim is more expensive than Mezim, since it is included in the list of highly effective enzyme medicines of the latest generation.
Like the original, the analogue is characterized by a wide range of applications. Micrazim is prescribed for:
- cystic fibrosis;
- chronic form of pancreatitis;
- malignant tumors in the pancreas;
- replacement treatment after pancreatic surgery;
- digestive disorders after surgery on the gallbladder, stomach, intestines;
- weakening of the contractile function of the intestinal tract;
- cholecystitis;
- gallstones;
- violation of bile secretion;
- blockage of the bile ducts.
Mikrasim is also recommended for healthy adults and children to take when overeating, eating heavy and fatty foods, poor diet, or inactive lifestyle.
The drug can be used as a means to prepare the digestive tract for X-ray or ultrasound monitoring of the abdominal organs.
The medicine is allowed to be taken by young children and pregnant women. But you need to take into account that the medicine can cause constipation in children. It is forbidden to use Mikrasim in case of acute pancreatitis and sensitivity to the active substance in the drug.
A rare side effect is an allergic reaction. An overdose of the drug may cause nausea, abdominal pain, constipation, diarrhea, and hyperuricemia.
Cheaper similar products
Drugs similar to Mezim are available in both tablets (dragées) and capsules. They belong to the category of natural enzyme medicines and improve the quality of the food processing process.
Acidin-pepsin
Available in tablet form. The medicine contains betaine hydrochloride (acidin) and pork pepsin. Similar to pancreatin, pepsin is an enzyme substance.
Characteristics of pepsin
Acedin-pepsin is often used for dyspepsia, achylia, hypo- and anacid gastritis, as well as for disorders that are associated with a decrease in the acidic environment of the stomach. Typically, adults are prescribed 2 tablets 3-4 times a day, either with or after meals. The tablets should be dissolved in ½ glass of water. The drug is contraindicated in people with:
- increased sensitivity to acidin or pepsin;
- stomach and duodenal ulcers;
- erosive gastroduodenitis.
Unienzyme
This enzyme medicine is available in tablet form. The main components of the medicine are fungal diastase and papain. Recommended for use for the following symptoms:
- nausea, flatulence (including after surgery), bloating, diarrhea;
- preparation for various gastrointestinal examinations;
- with poor functioning of the pancreas, prolonged pancreatitis, liver disease.
Description of Unienzyme
The medicine is recommended for adults and children over 7 years old, 1-2 tablets after meals. The drug should be swallowed whole and washed down with liquid. The use of the drug is contraindicated in patients under 7 years of age, as well as in patients with stomach and duodenal ulcers, liver diseases and specific sensitivity to the composition of the drug.
Panenzyme
Release form: tablets that dissolve in the intestines. Consists of pancreatin with minimal enzymatic activity. Used to optimize digestion. The dosage is prescribed individually for each patient. This depends on the degree of enzyme deficiency and diet maintenance. Typically, 1-2 tablets are prescribed with meals. The list of contraindications includes chronic pancreatitis in the acute stage and allergies to Panenzyme components.
Enzistal
Enteric tablets, the main substances of which are pancreatin, hemicellulase and bile extract. Scope of application:
- violation of the exocrine function of the pancreas;
- ulcerative colitis;
- colon irritation;
- improved digestion;
- preparation for examination of the gastrointestinal tract.
Indications and contraindications for the use of Enzistal
Children over 6 years old are prescribed 1 tablet immediately after meals. Adults can take the drug before meals. If necessary, the dosage can be increased to 2 tablets. Enzistal is contraindicated in case of increased sensitivity of the body to pancreatin, acute hepatitis, intestinal obstruction, cholecystitis and children under 6 years of age.
Fermentium
The active element of Enzyme is pancreatin, which helps improve digestion. The medicine is produced in the form of tablets. Prescribed for dyspepsia, consumption of fatty and spicy foods, which are difficult for the body to process. It is also prescribed for bloating, gastrectomy, pancreatectomy, and diseases that are accompanied by insufficiency of the exocrine part of the gland.
The medicine should be taken orally before or during meals for adults and children over 6 years of age, 1-2 tablets per day. The dose can be changed and set by the doctor individually.
Main contraindications for taking Enzyme:
- acute pancreatitis;
- intestinal obstruction;
- hepatitis;
- calculous cholecystitis.
What to choose - Abomin or Mezim?
Abomin is a cheap Russian analogue of Mezim, based on rennet enzymes isolated from veal stomachs. The medicine is sold in tablet form. Improves digestion in patients with enzyme deficiency in gastric juice. Effective for:
- gastritis;
- low stomach acidity;
- gastroenteritis;
- enterocolitis;
- difficult and painful digestion;
- ahilia.
It is not recommended to take the medicine for pregnant women, breastfeeding mothers, and patients with enzyme intolerance.
Also, the drug should not be given to young children who experience vomiting and regurgitation syndrome. Sometimes Abomin gives side effects: nausea and short-term heartburn.
The analogue is cheaper than the original drug, but is considered a high-quality medicine. Therefore, many people prefer to buy Abomin instead of Mezim.
Analogues of Digestin
Digestin is identical to the drug Mezim.
The pharmaceutical market widely presents drugs that have similar properties, but different active ingredients. One of these products is Digestin syrup. This is a complex drug. It contains 3 digestive enzymes - papain, pepsin, sanzim-2000. What each substance is responsible for:
- Pepsin is an analogue of gastric juice that breaks down protein fractions.
- Papain - has a similar effect, but works in both alkaline and neutral environments. The enzyme is obtained by crystallization of papaya juice.
- Sanzym-2000 is a complex of more than 30 natural enzymes. Produced from mushrooms of the species Aspergillus oryzae.
Indications for the use of Digestin:
- Dyspeptic phenomena
- Digestive disorders due to lack of enzymes
- Gastritis
- Rehabilitation after acute and chronic pancreatitis
- Children with congenital and chronic functional pathologies of the stomach
Contraindications to taking Digestin:
- Intolerance to simple and complex sugars
- Ulcer of any part of the stomach, intestines, duodenum
- Hyperacid gastritis is a chronic inflammatory process accompanied by an increased pH of gastric juice
- Anorexia
Recommended doses:
- Baby up to 1 year of age – 0.5 tsp. 3 times a day
- From 1 to 14 years – 1 tsp. 3 times a day
- From 14 and older – 1 tbsp. l. 3 times a day
The duration of treatment depends on the patient’s diagnosis and is determined by the attending physician. Side effects of Digestin are unlikely if all recommendations are followed. Allergic reactions to components occur rarely.