Novosept Forte spray for places. approx. dosage 25ml in plastic. cylinder with valve dosage actions in pack. No. 1

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Manufacturers: Odicos BV

Active ingredients

  • Tetracaine
  • Cetylpyridinium chloride
  • Zinc sulfate

Disease class

  • Acute pharyngitis, unspecified
  • Acute gingivitis
  • Chronic gingivitis
  • Stomatitis and related lesions
  • Other and unspecified lesions of the oral mucosa
  • Acute tonsillitis, unspecified

Clinical and pharmacological group

  • Not indicated. See instructions

Pharmacological action

  • Antifungal
  • Local anesthetic
  • Antibacterial local action
  • Bactericidal

Pharmacological group

  • Antiseptics and disinfectants in combinations
  • Local anesthetics in combinations

Release form

Pastilles (24pcs)

Anise-licorice lozenges: flat round, beveled edge lozenges with a rough surface, brown in color with a specific odor. Uneven coloring, the presence of air bubbles in the caramel mass and slight unevenness of the edges are allowed.

Eucalyptus-menthol lozenges: flat round, beveled edge lozenges with a rough surface, greenish-blue color with a whitish tint with a specific odor. Uneven coloring, the presence of air bubbles in the caramel mass and slight unevenness of the edges are allowed.

Honey-lemon lozenges: flat round, beveled edge lozenges with a rough surface, yellow in color with a specific odor. Uneven coloring, the presence of air bubbles in the caramel mass and slight unevenness of the edges are allowed.

Orange lozenges: flat round, with a beveled edge, lozenges with a rough surface, orange in color with a specific odor. Uneven coloring, the presence of air bubbles in the caramel mass and slight unevenness of the edges are allowed.

Novosept Forte lozenges

Instructions for medical use of the drug

Description of pharmacological action

It has antimicrobial (bactericidal), antifungal, local anesthetic effect due to its active components.

Indications for use

Local treatment: - inflammation of the mucous membranes of the oral cavity and larynx (stomatitis, gingivitis, tonsillitis, pharyngitis); - damage to the oral cavity.

Release form

Lozenges (anise-licorice, eucalyptus-menthol, honey-lemon, orange) 1 lozenge cetylpyridinium chloride 1.5 mg tetracaine hydrochloride 0.1 mg zinc sulfate 13.3 mg for contour charunkov or without charunkov Packages 2, 4, 6, 8, 10 or 12 pcs.; in a cardboard pack there are 1, 2, 3, 4, or 5 packages.

Pharmacodynamics

Novosept Forte contains antimicrobial (bactericidal), antifungal, and analgesic agents, containing some of its active components. Cetylpyridinium chloride is an antiseptic from the group of quaternary ammonium compounds, which can be added to cationic surfactants. Volodya has a bactericidal action against a wide range of gram-positive and, to a lesser extent, gram-negative bacteria. The antimicrobial activity of cetylpiridinium is due to its nonspecific interaction with various components of bacterial cells: membrane, ribosomes, proteins and enzymes, as a result of which the osmotic reaction is disrupted food, metabolism, carbohydrate and protein metabolism, and all this leads to the death of the bacterium. Cetylpyridinium also inhibits various groups of viruses and fungi. Inactive against bacterial spores. Tetracaine hydrochloride is an effective local anesthetic agent that can relieve or reduce pain. Zinc is an oligoelement that stimulates the immune system.

Use during pregnancy

Contraindications.

Contraindications for use

— hypersensitivity to drug components, local anesthetics; - damage to the integrity of the mucous membranes; - gostra nirkova or pechenkova lack of availability; - vagusness; - period of breastfeeding; - child's age.

Side effects

Possible allergic reactions (kropivyanka, itching, anaphylactic shock, loss of ability).

Directions for use and doses

Rozmoktuvati, not rozzhovuchi. Let's grow up - 4-6 lozenges per day at an interval of 2 years. The initial course of treatment is no more than 5 days.

Overdose

Symptoms: vomiting, pale skin, bradycardia, suppression of the respiratory center, apnea. In case of overdose, it is necessary to take off Novosept Forte and go to the doctor.

Special instructions for use

If illness is accompanied by high temperature, headache, fatigue, and if you are not afraid of any swelling for 5 days from the beginning of treatment, then go to the doctor. Trival bathing (more than 5 days) can lead to disruption of the natural microflora of the mouth and throat, with a risk of development of pathogenic bacteria and fungi. Instructions for patients with diabetes: 1 lozenge containing 2.5 g of sugar.

Storage conditions

In a dry, protected place in a light place, at a temperature not exceeding 25 ° C.

Best before date

24 months

ATX classification:

A Digestive tract and metabolism

A01 Dental preparations

A01A Dental preparations

A01AD Other preparations for topical use in diseases of the oral cavity

A01AD11 Other preparations for topical use in diseases of the oral cavity

pharmachologic effect

Novosept has a bactericidal, antifungal, local analgesic effect due to its active components: Cetylpyridinium chloride is an antiseptic from the group of quaternary ammonium compounds, it belongs to the cationic surfactant. It has a bactericidal effect against a wide range of gram-positive and, to a lesser extent, gram-negative bacteria. The antimicrobial activity of cetylpyridinium is due to its nonspecific interaction with various components of the bacterial cell: membrane, ribosomes, proteins and enzymes, as a result of which osmotic balance, respiration, carbohydrate and protein metabolism are disrupted, and all this leads to the death of the bacterium. Cetylpyridinium also suppresses certain groups of viruses and fungi. Inactive against bacterial spores. Tetracaine hydrochloride is an effective local anesthetic that quickly relieves or reduces pain. Zinc - oligoelements, stimulates the immune system.

Novosept Forte spray for places. approx. dosage 25ml in plastic. cylinder with valve dosage actions in pack. No. 1

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Herkel BV, Netherlands, ordered and supervised by Natur Produkt Europe BV

Over the counter

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Novosept® Forte

Dosage form:

Spray for topical use, dosed

Composition per 1 dose / per 100 g:

Active ingredients: Cetylpyridinium chloride - 0.500 mg / 0.250 g Tetracaine hydrochloride - 0.034 mg / 0.017 g Zinc sulfate monohydrate - 2.746 mg / 1.373 g

Excipients: glycerol 85%, ethanol 96%, sucrose, mint flavor, eucalyptus oil, honey flavor, purified water.

Description

Spray in a plastic bottle with a metering valve. The contents of the container are a colorless or yellowish liquid with a mint odor.

Pharmacotherapeutic group

Other preparations for local treatment of the oral cavity.

ATX code: A01AD11

pharmachologic effect

NovoSept Forte has a bactericidal and local anesthetic effect. Cetylpyridinium chloride, an antiseptic from the group of quaternary ammonium compounds, has a bactericidal effect against a wide range of gram-positive and, to a lesser extent, gram-negative bacteria, has variable antifungal activity, is effective against some viruses, and is inactive against bacterial spores. Tetracaine hydrochloride is a local anesthetic; relieves or reduces pain by blocking the transmembrane transport of Na+ ions. Zinc sulfate, when applied topically, has an antiseptic, astringent and drying effect.

Pharmacokinetics

Since NovoSept Forte is a combination drug for local use, pharmacokinetic studies are not possible.

Indications for use

Local treatment of inflammation of the mucous membranes of the oral cavity and pharynx: stomatitis, gingivitis, tonsillitis, pharyngitis. To relieve pain and other symptoms associated with mouth and throat infections. It can be used both for mild forms and as part of combination therapy for more severe diseases.  

Contraindications

Hypersensitivity to the components of the drug, local anesthetics, disruption of the integrity of the mucous membranes, acute renal or liver failure, pregnancy, lactation, children under 18 years of age.

With caution - with a decrease in plasma cholinesterase, arrhythmia, AV blockade, when driving a vehicle, with diabetes (one dose of the drug contains 0.0025 XE, the maximum daily dose is 0.045 XE).

Directions for use and doses

Locally. The drug is sprayed onto the mucous membrane of the mouth and pharynx while holding your breath.

Adults: 3 injections per dose 4-6 times a day with an interval of 2 hours.

The usual course of treatment is no more than five days.

Side effect

Allergic reactions are possible (urticaria, itching, anaphylactic shock, difficulty swallowing), nausea, vomiting.

Overdose

Symptoms: nausea, vomiting, diarrhea, pale skin, bradycardia, depression of the respiratory center, respiratory arrest.

In case of overdose, you must stop taking the drug and consult a doctor.

Interaction with other drugs

Medicines that inhibit cholinesterase (antimyasthenics, cyclophosphamide, demecarium, ecothiophate, insecticides, isofluraphate, thiotepa) reduce the metabolism of tetracaine hydrochloride and increase its toxicity.

When taken simultaneously with anticoagulants (dalteparin, enoxaparin, heparin, warfarin), the risk of bleeding increases.

When used with monoamine oxidase inhibitors (furazolidone, procarbazine, selegiline), the risk of lowering blood pressure increases.

Tetracaine hydrochloride enhances and prolongs the effect of muscle relaxants.

Beta blockers slow down the metabolism of tetracaine hydrochloride, increasing its toxicity (decreased hepatic blood flow).

Zinc is incompatible with silver salts, quinine, ichthyol, citral (forms poorly soluble compounds), with alkali-reactive substances (forms zinc oxide hydrate), with protargol (subject to coagulation).

Zinc reduces the absorption of tetracyclines and copper (should be used no earlier than 2 hours after taking these medications).

Thiazide diuretics increase the excretion of zinc in the urine.

Folic acid may interfere with the absorption of zinc to a small extent.

High doses of iron, penicillamine and other complexing drugs significantly reduce the absorption of zinc (should be used no earlier than 2 hours after taking these drugs).

Cetylpyridinium is not compatible with soaps and other anionic surfactants.

special instructions

If the disease is accompanied by high fever, headache, nausea, and if no improvement is observed within 3 days from the start of treatment, the drug should be discontinued.

Long-term treatment (more than 5 days) can cause an imbalance in the natural microflora of the oral cavity and pharynx with the risk of developing pathogenic bacteria and fungi, which is a contraindication for further use of the drug.

Release form

Dosed spray for topical use.

25 ml (at least 100 doses) in a plastic bottle with a dosing valve. 1 cylinder in a cardboard box with instructions for use.

Storage conditions

At a temperature not higher than 25°C. Keep out of the reach of children!

Best before date

2 years. Do not use after the expiration date.

Conditions for dispensing from pharmacies

Over the counter.

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** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use Novosept Forte, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.

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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Novosept Forte is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!

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