Priorix vaccine 1 dose 1 piece lyophilisate for preparing a solution for intramuscular and subcutaneous administration

Priorix is ​​an imported vaccine against measles, rubella and mumps. Manufacturer: GlaxoSmithKline Biologicals sa, Belgium. The vaccine is proven to be highly effective: antibodies against measles are detected in 98% of those vaccinated, against rubella in 99% and against mumps in 96%. Priorix fully complies with WHO requirements for the production of biological products.

Why vaccinate your child against measles?

Measles is one of the most dangerous “childhood” diseases. Firstly, it is extremely contagious: the chances of getting sick after contact with someone with measles are close to 100%. A decrease in the percentage of vaccinated children, even by a small amount, immediately results in a surge in the incidence of measles. Already in the 2000s, epidemics were recorded in such prosperous countries as Ireland and the USA: the reasons were the availability of air travel and refusals to vaccinate. Secondly, measles has a high mortality rate (although not as high as tetanus and diphtheria), and children under 5 years of age are especially susceptible to it. Measles still has no specific treatment – ​​only symptomatic treatment. In addition, it causes severe complications on the respiratory system, including bronchitis and pneumonia, and can also lead to partial loss of hearing or vision in the child.

Vaccine composition and application features

The composition of the vaccine is weakened mumps viruses (Jeryl Lynn-strain), measles (Schwarz-strain) and rubella (Wistar RA 27/3-strain). This combination allows you to immunize the patient against three diseases at once, using only one injection.

Indications

  • Planned prevention of any of the three diseases for adults and children over one year of age.
  • Emergency prevention. It is used after an unvaccinated patient has come into contact with the measles virus for 3 days. Allows you to alleviate the duration, symptoms and course of the disease.

Why vaccinate your child against rubella?

It is known that rubella is most dangerous for pregnant women, since it has an extremely negative effect on the fetus: more than half of newborns experience deafness, and blindness and heart disease are also common. Therefore, the advisability of rubella vaccination for women planning pregnancy seems to be beyond doubt. However, parents often ask the question: why vaccinate a one-year-old girl or, especially, a boy against rubella? After all, it is known that in most cases rubella is quite mild?

As in the case of mumps, the most well-known complication among the people is far from the only one and, alas, not even the most terrible. Progressive rubella panencephalitis, a rare but terrible complication, most often affects boys aged 8 to 19 years. With this complication, a person’s intellect gradually fades and motor functions die off, and it ends with dementia and death. Other complications from rubella that do not discriminate by gender include arthritis, pneumonia and hepatitis.

Vaccination scheme

In Russia, vaccination is usually carried out in accordance with the National Calendar of Preventive Vaccinations. If the vaccination schedule is violated, it is possible to discuss an individual vaccination plan with your doctor.

Primary vaccination against measles, rubella, mumps is recommended at the age of 12 months and consists of a single dose of the vaccine. Subsequent revaccination is performed at the age of 6 years and also involves a single injection of the vaccine preparation. Using the drug Priorix is ​​very convenient - the vaccination schedule is easy to understand and remember for parents, and is also the least traumatic for the child, due to fewer injections.

Girls of puberty are additionally vaccinated against rubella at 13 years of age. You can also get vaccinated if they have not been vaccinated before or have been vaccinated once with any of the vaccine preparations.

Clinical studies have shown the effectiveness of the Priorix vaccine. A significant advantage of the Priorix vaccine is its compatibility with other vaccines except BCG. This means that other vaccinations can be given on the same day, but in different areas of the body. It has been proven that combined use does not affect the effectiveness of immunization and tolerability.

Why vaccinate your child against mumps?

Mumps (mumps) is not a deadly disease, but can lead to extremely unfavorable complications. It gained fame due to the fact that it is a fairly common cause of infertility in men, which develops as a result of orchitis - inflammation of the testicles. The fact is that the mumps virus affects glandular tissue and is not limited to the postauricular salivary glands (although they are, indeed, usually affected first), but can develop in the tissues of the thyroid gland, pancreas, testicles in boys or ovaries in girls.

Two of the most common myths about the vaccine against it are associated with this feature of mumps. First: the vaccine causes infertility in boys. Of course, this is not true. When grafting, testicular tissue is not affected. Second: there is no point in vaccinating boys before puberty. And this is not so - infertility is caused not by low-quality sperm, but by atrophy of testicular tissue, which, unfortunately, does not depend on age. And high-quality immunity is formed after revaccination, and you may simply not have time to vaccinate your child before he gets sick.

The second question, no less frequent: if mumps is dangerous only for boys, why vaccinate girls? Just for the sake of the notorious population immunity? Of course not. The fact is that, in addition to orchitis, partotitis can cause pancreatitis, and this is lifelong, because the pancreas tissue is not restored; as well as encephalitis and meningoencephalitis - the most dangerous types of brain inflammation. Not very often, but it still happens that the experience of mumps ends in deafness.

Contraindications

Priorix vaccination is allowed when the immune system is normally active. With the permission of a doctor, vaccination is allowed even for HIV-positive patients in the absence of clinical symptoms.

Administration of the vaccine is contraindicated in the following conditions:

  • acute infectious diseases (intestinal, respiratory) - administration of the vaccine is permitted after persistent relief of fever;
  • any gestational age;
  • previously recorded fact of allergy to Priorix;
  • intolerance to any component of the vaccine.

If you are intolerant to chicken eggs or neomycin, if there has been no anaphylactic reaction, the drug can be administered.

For breastfeeding women, the decision to vaccinate is made individually.

When planning a pregnancy, the period between vaccination and conception should be at least 3 months.

The cost of vaccination with Priorix in Finland is 150 euros.

Possible side effects of Priorix

The specificity of the vaccine against measles, rubella and mumps is that it gives two waves of reaction: the first - within 24 hours after vaccination and the second - approximately 9-10 days after it. The child's condition should be carefully monitored during these periods of time.

In 60% of cases, Priorix vaccination is tolerated by the child without any consequences.

In the remaining cases, the most common occurrence is a rise in temperature, which accompanies the body's production of protective antibodies. Runny nose, cough, hives, pain and swelling at the injection site are also common.

Less common consequences of vaccination are upper respiratory tract infections, otitis media, bronchitis, nervousness, insomnia, conjunctivitis, febrile convulsions.

If any symptoms last longer than two days, you should consult a doctor.

The effectiveness of the Priorix vaccine

When a vaccine is administered, the human body produces antibodies in response to foreign agents. Numerous clinical trials were conducted with the Priorix vaccine on a large statistical sample, which showed the high effectiveness of the drug. After vaccination, protective bodies against measles were found in 98% of those vaccinated, against mumps - in 96%, and against rubella - in 99%. A repeated test for antibodies to viruses a year later revealed active antibodies against measles and rubella in the same number of vaccinated people, and against mumps in 88% of those examined.

The Priorix vaccine has been approved by international organizations (such as WHO) and meets all safety and effectiveness requirements.

How to prepare for the Priorix vaccination

To properly prepare for vaccination, you should protect your child from possible consequences. Firstly, for several days before and after vaccination you should not visit crowded places or contact people who are known to be sick (if you have to, reschedule the vaccination). Secondly, carefully monitor possible manifestations of ARVI in the child: he must be completely healthy. You should also not vaccinate if your child is actively teething.

It is necessary to eat light, healthy foods, do not overindulge in sweets and allergens, and drink more clean water. You should not introduce new complementary foods on the day of vaccination.

The child’s room, or better yet the entire apartment, should be well ventilated. The indoor humidity level should be maintained at least 65%.

You can give your child an antihistamine, such as Zyrtec, for several days before and after the vaccination.

Priorix, instructions for use (Method and dosage)

The vaccine is intended for subcutaneous (0.5 ml dose) or intramuscular administration.

Intravenous administration of the drug is not allowed.

According to the Russian preventive vaccination calendar, vaccination with Priorix is ​​indicated for pediatric patients from 12 months with further revaccination at 6 years. Priorix can also be prescribed to girls aged 13 years who have not previously been vaccinated or who have received only one vaccination with rubella , measles and mumps vaccines (monovalent or combined).

Preparation of solution for injection

Immediately before administration, the contents of the ampoule or the attached filled syringe with a solvent are added to the vaccine vial at the rate of 0.5 ml per dose.

The bottle is thoroughly shaken until a homogeneous solution is formed (a clear liquid of light red or light orange color). The dissolution time of the powder should not exceed 60 seconds.

If the prepared solution takes on a different color or has foreign inclusions, the vaccine should not be used.

To administer Priorix, use another sterile needle. When using the drug in multi-dose packaging, a new syringe with a sterile needle must be used for each new intake.

To avoid possible complications, the prepared solution must be used within 8 hours and stored in a temperature range from 2°C to 8°C (in the refrigerator). The drug is removed from the bottle while observing all the rules of asepsis .

Vaccination at MC "SANMEDEXPERT"

It is better to prevent any disease than to treat it. It is much simpler, safer for health and more financially profitable. If you want to protect yourself and your loved ones through vaccination, contact us. Our center has been providing impeccable medical services for 10 years. All specialists have more than 5 years of experience and regularly improve their skills. Doctors closely monitor the well-being of patients after vaccination and are especially attentive to children.

You can find out if Priorix is ​​in stock by calling: +7 (499) 678-03-03. You can also order a call back on the website.

Reviews of Priorix

Reviews about Priorix were divided approximately 60% (positive) to 40% (negative). It should be remembered that any vaccinations carry a certain risk of possible complications, ranging from stress from the injection itself to the development of anaphylactic reactions (extremely rare). When choosing a vaccine, you should consult with specialists and follow all measures for storing and transporting the drug.

The Priorix vaccine is often compared to domestically produced vaccines, but opinions are so different that it has not been possible to identify an absolute leader. The undoubted advantage of Priorix is ​​its single administration compared to domestic analogues, which are administered twice. The downside for allergy sufferers is considered to be the production of Priorix based on chicken eggs, while the Russian vaccine is made using quail eggs.

The side effects that occur after vaccination with both the Belgian and our vaccine are most often the same and consist of increased body temperature, mild cough, rash , and slight runny nose. Serious complications are extremely rare and often occur when the temperature conditions for storage and transportation are not observed.

Check the storage conditions of the drug, ask questions on professional forums, for example, on the website of Dr. Komarovsky .

special instructions

A history of contact dermatitis neomycin , as well as an allergic reaction to chicken eggs, excluding anaphylactic reaction , are not a contraindication to vaccination .

The vaccine can be administered to patients with asymptomatic HIV infection and AIDS .

For acute intestinal and other diseases, as well as mild acute respiratory viral infections

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