Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Not a medicine. Contains a suspension of live lactic acid bacteria of three patented strains , which have a positive effect on the microflora of the reproductive system. This probiotic is designed for intimate protection of women. It restores microflora disturbed by taking antibiotics , contraceptives, menstruation , menopause or pregnancy . Shows pronounced antagonism against pathogens: Prevotella bivia, Candida albicans, Gardnerella vaginalis, uropathogenic strains of Escherichia and streptococcus .
Provag blocks the migration of pathogenic microorganisms, prevents their reproduction in the vagina and urethra, restores normal bacterial flora and physiological pH . This is an innovative drug because it has a unique quantitative composition and ratio of bacteria. It is used in the treatment of disturbed flora and for the prevention of its violations.
The gel additionally provides care for the external genitalia in case of discomfort. Propylene glycol and glycerin included in the composition provide hydration and, accordingly, eliminate the feeling of dryness and itching. The formation of a gel biofilm creates a calming effect.
Pharmacokinetics
Data not provided.
According to WHO, 78% of women have disorders of the vaginal microflora , called vaginal dysbiosis (dysbiosis). There are a dozen reasons for the occurrence of this disease, but the result is always the same: health problems, discomfort, self-doubt, and, as a result, depression - the basis for other, more serious diseases.
Introducing Provag , an oral probiotic designed to provide intimate protection to women. Provag restores the microbiological balance in the vagina, disturbed by treatment with antibiotics, taking contraceptives, menstruation, pregnancy, visiting the pool and menopause.
The drug Provag contains 3 patented strains that provide better effectiveness compared to single strains and, at the same time, the natural microflora of the vagina.
Provag blocks the natural migration of microorganisms, preventing the proliferation of pathogens in the vagina and urethra through antagonistic effects; restores the physiological bacterial flora of the vagina and the normal pH value, which ensures inhibition of excessive growth of pathogenic microorganisms. This is a truly innovative drug - thanks to the unique quantitative composition and ratio of bacteria and mechanism of action.
The drug Provag was awarded the Złoty Otis (“Golden Otis”) prize in the “Debut of the Year” category. This trust mark is the most prestigious consumer award in Poland, and has three functions: educational, consumer and social. Provag has recommendations from the Polish Gynecological Society and is in demand among doctors.
In November 2012, the manufacturer of the drug Provag, the company IBVS BIOMED S.A. (“IBSS BIOMED SA”) became a finalist in the XXIII competition “Goods and Services” - this competition is held annually with the support of the Ministry of Foreign Affairs. The company was about, as a sign that the quality of the drug Provag they produce fully complies with European standards.
Use of the drug Provag as an adjuvant:
- After sanitization of pathogenic bacteria and fungi
- After using metronidazole and co-trimoxazole
- During and after antibiotic therapy
- For secondary and recurrent bacterial and fungal infections of the genitourinary system
Use of the drug Provag as a prophylaxis:
- when using a swimming pool, jacuzzi, frequent travel
- during perimenopause
- at the end of the postpartum period
- before and after surgical operations on the genitourinary system
Properties of Provag strains: Provag demonstrates pronounced antagonism against aerobic and anaerobic pathogens, in particular Gardnerella vaginalis, Prevotella bivia, uropathogenic strains of Escherichia coli, Streptococcus agalactiae, Candida albicans.
Packaging: 1 blister of 10 capsules each. 1 capsule contains at least 108 CFU of lyophilized lactic acid bacteria in the ratio indicated below: Lactobacillus gasseri 57C
– 50%,
Lactobacillus fermentum 57A
– 25%,
Lactobacillus plantarum 57B
– 25%
Directions for use: 1 capsule per day orally with water. The duration of use of the product is at least 20 days. Do not exceed the recommended daily dose. Before use, you should consult your doctor. Storage conditions: store at a temperature of 2-8°C (in the refrigerator) out of the reach of children. Protect from moisture. Shelf life: 2 years from the date of manufacture. Attention! If stored outside the refrigerator at temperatures below 25°C, it should be used within 4 weeks. FOOD SUPPLEMENT IS NOT A MEDICINE
Indications for use
- maintaining physiological microflora in the vagina and urinary system;
- restoration of physiological microflora after elimination of pathogenic flora;
- during treatment with antifungal and antibacterial drugs;
- recurrent infections of the reproductive system;
- period of menstruation;
- during menopause ;
- after operations on the genitourinary organs;
- preventively when visiting swimming pools and jacuzzi, after depilation in the intimate area.
Provag
Provag is an oral probiotic designed to provide intimate protection to women. Provag restores the microbiological balance in the vagina, disturbed by treatment with antibiotics, taking contraceptives, menstruation, pregnancy, visiting the pool and menopause.
Capsules for oral use. Biologically active food supplement.
Action Provag contains a lyophilized suspension of live lactic acid bacteria, which have a positive effect on the microflora of the genitourinary system of women, due to their strong probiotic properties. The physiological bacterial flora of the vagina is represented mainly by lactic acid bacteria (genus Lactobacillus). These bacteria produce hydrogen peroxide, which has antibacterial properties, and lactic acid, which is responsible for maintaining the appropriate pH level. Typically, vaginal secretion has an acidic environment, so it prevents the growth of pathogenic microorganisms that contribute to the development of urogenital infections. A decrease in the number of lactic acid bacteria increases the risk of developing vaginal infections.
The microbiological balance in the vagina can be disturbed during treatment with antibiotics, taking contraceptives, during menstruation, during pregnancy, menopause, in people who frequently visit swimming pools and perform hygienic procedures, for example, frequent washing of the vagina and when using tampons. The use of Provag will restore the physiological bacterial microflora of the vagina, maintain an appropriate pH level in the vagina and thereby prevent the growth of pathogenic microorganisms.
Indications Daily additional use of Provag helps maintain normal physiological bacterial microflora of the vagina and an appropriate pH level of the vagina. Provag can also be recommended for use in cases where the natural microbiological balance has already been disturbed and a change in the pH level of the vagina is possible.
Provag is recommended for use in the following cases: additionally daily to maintain normal physiological genitourinary bacterial microflora and an appropriate vaginal pH level; as a supporting agent for restoring the physiological genitourinary bacterial microflora and the appropriate pH level of the vagina, after eliminating pathogenic bacteria and fungi; additionally during and after treatment with antibacterial, antitrichomoniacal and antifungal drugs; additionally during and after treatment with metronidazole and cotrimoxazole; additionally for secondary and recurrent infections of the genitourinary system; during the perimenopausal period (during menopause); during and after menstruation; women before and after surgery on the genitourinary organs; women who often visit swimming pools, solariums, travel, and use jacuzzi.
Composition One capsule of Provag contains Active components: Lactobacillus - 109 CFU/g in the following proportion: 50% Lactobacillus gasseri 57C, 25% Lactobacillus fermentum 57A, 25% Lactobacillus plantarum 57B. Excipients: lactose, mannitol, magnesium stearate, milk, sucrose, sodium glutamate. The product contains saccharides and sweetener. When taken in large doses, it may have a laxative effect.
Dose and method of administration: 1 capsule per day orally with water. The duration of use of the product is at least 20 days. Do not exceed the recommended daily dose. Before use, you should consult your doctor.
Storage conditions Shelf life - 18 months. Store at a temperature of 2-6°C (in the refrigerator) out of the reach of children. Protect from moisture. Attention! If stored outside the refrigerator at temperatures below 25°C, it should be used within 4 weeks.
This drug is also presented on the website provag.ru
Section: Gynecology | Manufacturer: IBSS Biomed Print | ↑ Up
Provag, instructions for use (Method and dosage)
Provag capsules are taken one per day with meals, washed down with plenty of water. The course of treatment is from 20 days to a month. The recommended dose should not be exceeded.
Gel Provag, instructions for use
A dosed amount of gel is applied to the area of the external genitalia and perineum before bed once a day. Apply from front to back. If discomfort occurs during the day, additional use up to 2-3 times is possible. After use, tingling may occur.
Reviews about Provag
The physiological flora of the vagina is represented by lactic acid bacteria. They produce hydrogen peroxide , which has antibacterial properties, and lactic acid, which maintains an acidic environment. An acidic environment prevents the growth of pathogenic flora that causes urogenital infections. Reducing lactic acid bacteria carries a risk of developing vaginal infections.
In order to restore beneficial flora, probiotic antibiotics , as well as in certain physiological conditions ( menstruation , pregnancy ) . It can be considered as an adjuvant for the treatment of fungal and bacterial infections. The presence of two dosage forms (capsules and gel) makes its use convenient and the woman has the opportunity to choose. Capsules in a gelatin shell, which does not collapse in the stomach, exhibit their effect in the intestines, and the gel enhances the effect when applied topically. As a result, the microflora of not only the vagina, but also the intestines is restored, and this increases the immunity and immunity of the body to bacteria.
There are positive reviews of the capsules, which report that they were prescribed for frequent inflammatory diseases of the female genital area, recurrent thrush and vaginitis . antibiotic treatment . In this situation, the women took it and the antibiotic, with a two-hour break between them. As a result of several courses with breaks, an improvement in the general condition was observed and the frequency of exacerbations decreased.
- “... I periodically take it orally. I like the effect. Previously, in the middle of the cycle, discharge was bothersome and it was necessary to restore the microflora. The gynecologist advised me, I took 2 courses, everything returned to normal.”
- “... I love this drug and use it twice a year for prevention. “I’m fine with women’s health.”
- “... After two courses of Amoxiclav, I was prescribed Provag capsules. Interestingly, he restored the flora not only in the vagina, but also in the intestines - pain, bloating and colic disappeared.”
To enhance the effect, many women were simultaneously prescribed Provag gel, which made it possible to quickly normalize the vaginal microflora if it was disturbed. All consumers note its economical use - it contains 100 doses, which are enough for 3 months.
- “... A very lucky find for me! Extremely pleased with it. Pleasant in every way."
- “... Gel is an irreplaceable thing! Compact and convenient bottle with automatic dispenser. Quickly eliminates discomfort, itching and irritation, and moisturizes well.”
- “... I even like the gel better, because I think it’s more effective. It moisturizes well, after a day the discomfort disappears and the discharge decreases. At the same time, it does not leave marks on clothes.”
Provag caps No. 10
Compound
Active substances: Excipients: lactose, mannitol, magnesium stearate, milk, sucrose, sodium glutamate. Nutritional value:
Indications for use
Recommended as a biologically active food supplement for women over 18 years of age - a source of probiotic microorganisms (lactobacteria).
Contraindications
Individual intolerance to product components.
It is recommended to consult a doctor before use.
Directions for use and doses
Adults take 1 capsule 1 time per day with meals. Drink plenty of water. Duration of treatment is up to 1 month, but not less than 20 days. Do not exceed the recommended daily dose.
Storage conditions
Should be stored at a temperature of 2-6°C (in the refrigerator) out of the reach of children. Protect from moisture. If the product is stored outside the refrigerator at temperatures below 25°C, it should be used within 4 weeks.
Best before date
18 months.
special instructions
Dietary supplement (dietary supplement). Not a medicine.
Description
Provag contains a lyophilized suspension of live lactic acid bacteria, which have a positive effect on the microflora of the genitourinary system of women due to their strong probiotic properties.
The physiological bacterial flora of the vagina is represented mainly by lactic acid bacteria (genus Lactobacillus). These bacteria produce hydrogen peroxide, which has antibacterial properties, and lactic acid, which is responsible for maintaining an appropriate Ph level. Typically, vaginal secretion has an acidic environment, so it prevents the growth of pathogenic microorganisms that contribute to the development of urogenital infections. A decrease in the number of lactic acid bacteria increases the risk of developing vaginal infections.
The microbiological balance in the vagina can be disturbed during treatment with antibiotics, taking contraceptives, during pregnancy, menopause; in people who frequently visit swimming pools and perform hygienic procedures, for example, frequent vaginal rinsing and when using tampons.
Daily additional intake of Provag helps maintain normal physiological bacterial microflora of the vagina and the appropriate pH of the vagina. Provag can also be recommended for use in cases where the natural microbiological balance is already disturbed and a change in the pH level of the vagina is possible.
Provag is recommended for use in the following cases:
- additionally daily to maintain normal physiological genitourinary bacterial microflora and an appropriate vaginal pH level;
- as a supporting agent for restoring the physiological genitourinary bacterial microflora and the appropriate pH level of the vagina after eliminating pathogenic bacteria and fungi;
- additionally during and after treatment with antibacterial, antitrichomoniacal and antifungal drugs;
- additionally during and after treatment with metronidazole and clotrimoxazole;
- additionally for secondary and recurrent infections of the genitourinary system;
- during the premenopausal period (during menopause);
- during and after menstruation;
- women before and after surgery on the genitourinary organs;
- women who often visit swimming pools, solariums, travel, and use jacuzzi.
The product contains saccharides and sweetener. When taken in large doses, it can have a laxative effect.
A food supplement cannot replace a varied diet.
Provag price, where to buy
You can purchase the drug at any pharmacy. The price of tablets (capsules) in the amount of 10 pieces is 395-515 rubles, gel - 312-331 rubles.
- Online pharmacies in RussiaRussia
ZdravCity
- Provag caps.
230 mg 10 pcs. IBSS BIOMED SA 605 rub. order
