Pharmacological properties
Pharmacodynamics.
benzalkonium chloride is a cationic surfactant whose contraceptive properties are associated with the ability to destroy sperm membranes. after contact of benzalkonium chloride with sperm, their immediate immobilization occurs, and subsequently the destruction of their cell membrane and separation of the flagella from the heads. The contraceptive effect of the drug Erotex is also realized due to the thickening of cervical mucus and the formation of a film, which reduces the ability of sperm to penetrate through the external os of the cervix. The contraceptive effect is measured by the Pearl index; for benzalkonium chloride in the form of suppositories it is less than 1, that is, if used correctly and all requirements are met, the incidence of unwanted pregnancy is approximately 1% per year.
The drug does not affect libido and fertility, and has a reversible effect when discontinued.
Erotex also has an antiseptic and antimicrobial effect and reduces the risk of contracting sexually transmitted infections, but does not completely eliminate it.
Pharmacokinetics. The drug is not absorbed by the vaginal mucosa, but is only absorbed on its walls, is easily eliminated by douching with clean water or removed with physiological vaginal secretions, acts only locally and does not enter the systemic bloodstream. The duration of local action of Erotex is 4 hours.
Erotex vaginal suppositories with rose scent 18.9 mg No. 5x2
Name
Erotex supp vag with rose scent 18.9 mg in cont. cell pack №5x2
Compound
active ingredient: benzalkonium chloride; 1 suppository contains 18.9 mg of benzalkonium chloride—substances: Oil or rose, lemon, lipophilic
pharmachologic effect
Erotex is a local contraceptive. The active substance of Erotex - benzalkonium chloride - is a surfactant cationic substance that has a spermicidal effect due to its ability to destroy the cell membrane of the sperm. Benzalkonium chloride is able to immobilize sperm, destroy the membrane of their cells and separate the flagella from the heads. The contraceptive effect of Erotex is also due to its ability to influence the thickening of cervical mucus and the formation of a film, which prevents sperm from penetrating through the external cervical os. When the drug is used correctly, its contraceptive effectiveness is comparable to the effectiveness of intrauterine contraceptives and oral microdose contraceptives. In addition to the contraceptive effect, Erotex has antiseptic and antimicrobial properties, covering infectious agents such as chlamydia, gonococci, trichomonas, corynebacteria, enterococci, staphylococci, herpes simplex viruses type II and I, fungi of the genus Candida, cytomegalovirus, hepatitis B viruses and HIV. Thanks to the antimicrobial and antiseptic effect of the drug, the use of Erotex reduces the risk of contracting sexually transmitted infections. Erotex does not affect normal vaginal microflora (including Doderlein's bacillus) and hormonal levels. Erotex, being absorbed on the walls of the vagina, is not absorbed by the mucous membranes. The drug is removed independently with physiological vaginal secretions, and it can also be easily removed by douching with water. Erotex does not enter the systemic circulation, having an exclusively local effect. The duration of action of the drug is 4 hours.
Indications for use
Erotex is used for local contraception in women of reproductive age. Erotex is especially recommended for use:
- in cases of contraindications to intrauterine or oral contraception;
- in the lactation and postpartum period;
- during periods after termination of pregnancy;
- in cases of irregular sexual intercourse;
- in the perimenopausal period;
- during a break in the use of oral contraceptives or when replacing an intrauterine contraceptive device.
Erotex can be used as an independent contraceptive, as well as in combination with other contraceptives (for example, a condom).
Pregnancy and lactation
The use of Erotex by women during pregnancy is permitted.
Directions for use and doses
Erotex suppository must be removed from its protective packaging before use. Erotex is inserted deeply into the vagina. Erotex is recommended to be administered no later than 5 minutes before the start of sexual intercourse, since this period of time ensures uniform distribution of the drug in the vagina. One suppository of the drug is designed for only 1 sexual intercourse. If you have repeated sexual intercourse, you must administer another suppository of the drug Erotex.
Side effect
In some cases, when using the drug Erotex, a burning sensation in the vagina may be observed. Such side effects do not require special measures and are eliminated by douching with clean water. There are no systemic side effects of the drug Erotex.
Overdose
Cases of drug overdose have not been described.
Interaction with other drugs
Soap and soap-containing hygiene products can inactivate the active ingredient of Erotex - benzalkonium chloride, which entails the loss of the contraceptive effect of the drug. While using Erotex suppositories, you should not use other medications in vaginal form to avoid a decrease in the contraceptive effect of the drug and possible interactions. Release form: Erotex vaginal suppositories 18.9 mg, lavender scent No. 10, No. 5. Erotex vaginal suppositories 18.9 mg, rose scent No. 10, No. 5. Erotex vaginal suppositories 18.9 mg, lemon scent No. 10, No. 5.
Storage conditions
Storage conditions. Store at temperatures from +2 °C to +15 °C. Keep out of the reach of children.
Best before date
2 years. The drug should not be used after the expiration date indicated on the package.
Conditions for dispensing from pharmacies
Over the counter.
Indications
Local contraception for all women of reproductive age. the drug is used both in monotherapy and in combination with other methods, which enhances their contraceptive effect. the use of Erotex is especially advisable in cases where the advantages of local contraception are irrefutable:
if there are permanent or temporary contraindications to oral contraception or an intrauterine device (after childbirth, during breastfeeding, after termination of pregnancy, during menopause);
if necessary, occasional protection (irregular sex life);
when using oral contraception, if the woman forgot or took the pill late (in this case, Erotex should be additionally used on any days of the cycle);
as an adjunct to barrier contraception (vaginal diaphragm) or the presence of an intrauterine device, especially with the simultaneous use of certain medications (for example, NSAIDs).
Indications for use of the drug Erotex
Local contraception for women of reproductive age, especially in cases where its advantages are irrefutable:
- if there are contraindications to oral and intrauterine contraception;
- during the postpartum and lactation periods;
- in the period after termination of pregnancy;
- during the perimenopausal period;
- with irregular sexual intercourse;
- during the period of replacing an intrauterine device or a break in taking an oral contraceptive.
Erotex can be used in addition to any other contraceptive, including a condom.
Application
Before using the drug Erotex, you must remove the suppository from the protective packaging and, in a lying position, insert it as deep as possible into the vagina at least 5 minutes before sexual intercourse. During this time, the active spermicidal substance is evenly distributed in the vagina. in case of repeated sexual contact, it is necessary to introduce another Erotex suppository (one suppository per sexual contact).
When using the drug Erotex, it is necessary to take into account that suppositories have a moderate moisturizing effect.
Children. Erotex should not be used by children.
Special instructions for the use of Erotex
The drug must be used before each sexual intercourse, regardless of the phase of the menstrual cycle; in case of repeated sexual intercourse, another Erotex suppository must be administered (one suppository per sexual intercourse)! It is prohibited to use soap or other soap-based products for toileting the genitals for 2 hours before and 2 hours after sexual intercourse, since even small residues destroy the active ingredient of Erotex, and the contraceptive effect of the drug is lost. To do this, use only clean water. Vaginal douching is prohibited for 2 hours after sexual intercourse. If a woman is diagnosed with acute inflammatory diseases of the reproductive system, as well as in the case of exacerbation of chronic inflammatory diseases or detection of dysplastic changes in the epithelium of the vagina or cervix, contraception with Erotex is not recommended until the manifestation of the main clinical symptoms of the disease decreases. If another intravaginal drug is prescribed, Erotex contraception should be discontinued until the entire course of treatment is completed. Erotex can be used during pregnancy and lactation, as well as during menstruation.
special instructions
The contraceptive effectiveness of the drug Erotex largely depends on careful adherence to the rules for its use.
To achieve maximum effect, you should remember these rules and follow them:
the drug must be used before each sexual intercourse, regardless of the phase of the menstrual cycle (using the drug only on “dangerous days” reduces the effectiveness of the method);
in case of repeated sexual intercourse, it is necessary to administer another Erotex suppository (one suppository per sexual intercourse);
For genital hygiene, it is prohibited to use soap or other soap-based products for 2 hours before and 2 hours after sexual intercourse, since even slight residues destroy the active ingredient of Erotex. Only clean water should be used;
Do not douche the vagina within 2 hours after intercourse.
Erotex should not be used without a doctor’s permission if any vaginal diseases are detected.
Use during pregnancy or breastfeeding. The drug is a contraceptive and should not be used during pregnancy. When pregnancy occurs during contraception with benzalkonium chloride, no effect on the course of pregnancy was detected.
Benzalkonium does not pass into breast milk, so Erotex can be used during breastfeeding.
The ability to influence reaction speed when driving vehicles or working with other mechanisms. Does not affect.
Pharmacological properties of the drug Erotex
benzalkonium chloride is a cationic surfactant whose spermicidal effect is due to its ability to destroy sperm membranes. In a few seconds, benzalkonium chloride immobilizes sperm, destroys their cell membrane and separates the flagella from the heads. The contraceptive effect of the drug Erotex is also realized due to the thickening of cervical mucus and the formation of a film, which reduces the ability of sperm to penetrate through the external os of the cervix. If used correctly, the contraceptive effectiveness of Erotex is close to the effectiveness of microdose oral contraceptives and intrauterine devices. Erotex also has an antimicrobial and antiseptic effect, which applies to gonococci, chlamydia, trichomonas, enterococci, corynebacteria, staphylococci, fungi of the genus Candida , herpes simplex viruses type I and II, hepatitis B, cytomegalovirus and HIV, thereby significantly reducing the risk of contracting infections, sexually transmitted. The drug does not affect hormonal levels and normal vaginal microflora (Doderlein bacillus). Pharmacokinetics. The drug is not absorbed by the vaginal mucosa, but is only absorbed on its walls, is easily eliminated by douching with clean water or removed with physiological vaginal secretions, acts only locally and does not enter the systemic bloodstream. The duration of local action of Erotex is 4 hours.
Note!
Description of the drug Erotex p/z supp. No. 10 (rose) on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
