Hexicon D vaginal suppositories 8 mg 10 pcs


Hexicon vaginal suppositories 16 mg No. 10

A country

Russia
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Active substance

Chlorhexidine

Compound

Release form: Hexicon®, vaginal suppositories, 1 or 5 suppositories are placed in a blister pack. One contour blister pack with one suppository and two fingertips, one or two contour blister packs of 5 suppositories each, together with instructions for medical use of the drug, are placed in a cardboard pack. Composition: One suppository contains: active substance: chlorhexidine digluconate - 16 mg (chlorhexidine digluconate is used in the form of a solution (concentration 20%)); excipients: base for suppositories - a sufficient amount to obtain a suppository weighing 3.10 g - macrogol 1500 (polyethylene oxide 1500) 92 - 98%, macrogol 400 (polyethylene oxide 400) 8 - 2%. Quantity per package: 10 vaginal suppositories.

pharmachologic effect

Hexicon® is an antiseptic drug for topical use, active against protozoa, gram-positive and gram-negative bacteria, viruses, including: Treponema pallidum, Chlamidia spp., Ureaplasma spp., Neisseria gonorrhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Bacteroides fragilis, Herpes virus. Some strains of Pseudomonas spp., Proteus spp. are weakly sensitive to the drug, and acid-resistant forms of bacteria, bacterial spores, and fungi are also resistant. Hexicon® does not interfere with the functional activity of lactobacilli. Remains active (albeit somewhat reduced) in the presence of blood and pus.

Indications for use

Prevention of sexually transmitted infections (chlamydia, ureaplasmosis, trichomoniasis, gonorrhea, syphilis, genital herpes, etc.). Prevention of infectious and inflammatory complications in obstetrics and gynecology (before surgical treatment of gynecological diseases, before childbirth and abortion, before and after installation of an intrauterine spirals (IUD), before and after diathermocoagulation of the cervix, before intrauterine examinations). Treatment of bacterial vaginosis, colpitis (including nonspecific, mixed, trichomonas).

Mode of application

Intravaginally. Before use, the suppository is removed from the contour packaging. For treatment: 1 suppository 2 times a day, for 7–10 days. For the prevention of sexually transmitted infections: 1 suppository no later than 2 hours after unprotected sexual intercourse.

Interaction

Simultaneous use with iodine is not recommended. Hexicon® is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally. Toilet of the external genitalia does not affect the effectiveness and tolerability of Hexicon® vaginal suppositories, because the drug is used intravaginally.

Side effect

Possible allergic reactions, itching, which disappear after discontinuation of the drug

Contraindications

Hypersensitivity to the components of the drug.

Hexicon 16 mg 10 pcs. vaginal tablets nizhpharm

pharmachologic effect

Chlorhexidine is an antiseptic drug for local intravaginal use, active against protozoa, gram-positive and gram-negative bacteria, viruses, including Treponema pallidum, Chlamydia spp., Ureaplasma spp., Neisseria gonorrhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Bacteroides fragilis, Herpes simplex 2 type. Some strains of Pseudomonas spp., Proteus spp. are weakly sensitive to the drug, and acid-resistant forms of bacteria, bacterial spores, and fungi are also resistant. Chlorhexidine does not interfere with the functional activity of lactobacilli. Remains active (albeit somewhat reduced) in the presence of blood and pus.

Composition and release form Hexicon 16 mg 10 pcs. vaginal tablets nizhpharm

One tablet contains:

active ingredient - chlorhexidine bigluconate - 16.0 mg (in the form of chlorhexidine bigluconate solution 20% - 85.2 mg);

excipients: microcrystalline cellulose, pregelatinized corn starch, povidone K 17, stearic acid, lactose monohydrate. Vaginal tablets 16 mg. 5 or 10 tablets in a blister pack made of polyvinyl chloride film and printed varnished aluminum foil. 1, 2 blister packs of 5 tablets each or 1 blister pack of 10 tablets, together with instructions for use of the medicinal product, are placed in a cardboard pack.

Description of the dosage form

Vaginal tablets

Characteristic

Tablets are white or white with a yellowish tint, biconvex, oblong. Slight marbling of the surface is allowed.

Directions for use and doses

Intravaginally. Before use, it is recommended to moisten the tablet in water.

For treatment: 1 vaginal tablet 1-2 times a day for 7-10 days.

To prevent sexually transmitted infections: 1 vaginal tablet no later than 2 hours after unprotected intercourse.

If symptoms persist for more than 7 days, it is recommended to consult a doctor.

Use the drug only according to the method of use and in the doses indicated in the instructions for use. If necessary, please consult your doctor before using the medicine.

Pharmacodynamics

A local antiseptic with a predominantly bactericidal effect against gram-positive and gram-negative bacteria, and has a fungicidal and virucidal effect (against lipophilic viruses). Active against protozoa, gram-positive and gram-negative bacteria, viruses, including Treponema pallidum, Chlamydia spp., Ureaplasma spp., Neisseria gonorrhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Bacteroides fragilis, Herpes simplex type 2. Some strains of Pseudomonas spp., Proteus spp. are weakly sensitive to the drug, and acid-resistant forms of bacteria and bacterial spores are also resistant. Chlorhexidine does not interfere with the functional activity of lactobacilli. Remains active (albeit somewhat reduced) in the presence of blood and pus.

Pharmacokinetics

Systemic absorption after intravaginal use is negligible.

Indications for use Hexicon 16 mg 10 pcs. vaginal tablets nizhpharm

Treatment of bacterial vaginosis, colpitis (including nonspecific, mixed, trichomonas).

Prevention of infectious and inflammatory complications in obstetrics and gynecology (before surgical treatment of gynecological diseases, before childbirth and abortion, before and after installation of an intrauterine device (IUD), before and after diathermocoagulation of the cervix, before intrauterine examinations).

Prevention of sexually transmitted infections (chlamydia, ureaplasmosis, trichomoniasis, gonorrhea, syphilis, genital herpes) - use no later than 2 hours after sexual intercourse.

Contraindications

Hypersensitivity to chlorhexidine and other components of the drug, children under 18 years of age.

Application Hexicon 16 mg 10 pcs. Nizhpharm vaginal tablets during pregnancy and breastfeeding

The use of the drug during pregnancy and breastfeeding is possible only after a careful assessment of the expected benefit to the mother and the risk to the fetus and child.

special instructions

In childhood, it is recommended to use the drug Hexicon® D.

Overdose

Cases of overdose are unknown. When using the drug in accordance with the instructions for use, an overdose is unlikely.

Side effects Hexicon 16 mg 10 pcs. vaginal tablets nizhpharm

Allergic reactions and vaginal itching are possible, which disappear after discontinuation of the drug.

Severe allergic reactions, including anaphylaxis.

If any of the side effects indicated in the instructions get worse or you notice any other side effects not listed in the instructions, tell your doctor.

Drug interactions

Concomitant use with iodine-containing drugs used intravaginally is not recommended.

Chlorhexidine is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally.

Compatible with drugs containing a cationic group (benzalkonium chloride, cetrimonium bromide).

Hexicon® d (Hexicon d)

Manufacturer: NIZHFARM OJSC (Russia)

◊ vaginal suppositories. 8 mg: 5 or 10 pcs. Reg. No.: LS-000185

Clinical and pharmacological group:

Antiseptic for local use in gynecology

Release form, composition and packaging

Vaginal suppositories

white or white with a yellowish tint, torpedo-shaped, marbling of the surface is allowed.

1 sup.
chlorhexidine bigluconate*8 mg

* chlorhexidine bigluconate is used in the form of a solution (20% concentration).

Excipients:

base for suppositories - macrogol 1500 (polyethylene oxide 1500), macrogol 400 (polyethylene oxide 400) - a sufficient amount to obtain a suppository weighing 1.5 g.

5 pieces. — cellular contour packages (1) — cardboard packs. 5 pieces. — contour cell packaging (2) — cardboard packs.

Description of the active components of the drug "Heksikon® d"

pharmachologic effect

Antiseptic drug for local use.

Active against
gram-positive and gram-negative bacteria
- Treponema pallidum, Chlamydia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis;
protozoa
- Trichomonas vaginalis;
viruses
- Herpes simplex types 1 and 2.

Hexicon does not interfere with the functional activity of lactobacilli.

Remains active (albeit somewhat reduced) in the presence of blood and pus.

Indications

— prevention of sexually transmitted diseases (including gonorrhea, syphilis, trichomoniasis, chlamydia, ureaplasmosis, genital herpes);

— prevention of infectious and inflammatory complications in obstetrics and gynecology (before surgical treatment of gynecological diseases, before and after diathermocoagulation of the cervix, before intrauterine examinations);

- treatment of chronic exo- and endocervicitis, vaginitis (including nonspecific, mixed, trichomonas).

Dosage regimen

To prevent
sexually transmitted diseases,
1 soup is prescribed once. The drug should be used no later than 2 hours after sexual intercourse.

For treatment

1 soup is prescribed. 2 times/day for 7-10 days. If necessary, it is possible to extend therapy up to 20 days.

Side effect

Possible:

allergic reactions, itching, which disappear after discontinuation of the drug.

Contraindications

- hypersensitivity to the components of the drug;

- allergic reactions.

Pregnancy and lactation

The drug is not contraindicated for use during pregnancy and lactation (breastfeeding).

special instructions

In childhood, it is recommended to use the drug Hexicon D.

Overdose

Currently, no cases of overdose of Hexicon D have been reported.

Drug interactions

Hexicon D is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps. The presence of soap can inactivate chlorhexidine, so before using the drug, any remaining soap must be thoroughly rinsed off.

Conditions for dispensing from pharmacies

The drug is approved for use as a means of OTC.

Storage conditions and periods

The drug should be stored out of the reach of children, protected from light at a temperature not exceeding 25°C. Shelf life – 2 years.

Drug interactions

Hexicon D is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps. The presence of soap can inactivate chlorhexidine, so before using the drug, any remaining soap must be thoroughly rinsed off.

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