Fenkarol: description, when to use, dosage regimen

  1. How does Fenkarol for children (10 mg) work?
  2. What is it used for?
  3. What is treated with Fenkarol?
  4. How to give Fenkarol to children?
  5. Instructions for Fenkarol 10 mg
      Composition of the drug
  6. Pharmacological properties
  7. Indications for use
  8. Directions for use and doses
  9. Side effects
  10. Contraindications
  11. Precautionary measures
  12. Interaction with other drugs

An allergic reaction in children can be caused by almost anything, this especially applies to infants, whose bodies are just adapting to environmental conditions. For the same reason, it is very difficult to select antiallergic drugs for children, since adverse reactions may occur, but Fenkarol 10 mg has a high safety profile. This is the only antihistamine that can be prescribed to babies from birth.

Pharmacodynamics and pharmacokinetics

The active component of the drug, a derivative of quinuclidyl carbinol , reduces the effect of histamine (which is produced as an immune response to an allergen ) on the body. Its structure contains a cyclic quinuclidine nucleus , the substance has a significant distance between the nitrogen and the diphenylcarbinol .

Hifenadine blocks H1 receptors competitively, while activating the enzyme diamine oxidase . This enzyme is capable of breaking down about 30% of histamine . Thus, the drug is more effective compared to other allergy .

through the blood-brain barrier and has virtually no effect on the deamination of serotonin in the brain or monoamine oxidase .

The product relieves spasm of smooth muscles in the intestines , itching and discomfort due to allergies. The drug reduces hypotensive activity , maintains normal capillary , without clearly affecting blood pressure and the heart muscle. Unlike the well-known and widespread diphenhydramine and pipolfen , the drug does not depress the central nervous system and is present in brain tissue in small quantities. However, if the patient has a specific reaction to the component, mild sedation .

When administered intramuscularly, the maximum concentration of the active substance is achieved after half an hour. When taking the tablet form – after an hour. Accumulates mainly in the liver, kidneys and lungs. Then it undergoes metabolic , their products are excreted in the urine.

What therapeutic effect does

According to the instructions, Fenkarol tablets have a therapeutic effect in four areas:

  • relieve swelling;
  • relieve itching;
  • fight other manifestations of allergies - runny nose, lacrimation;
  • eliminate increased vascular permeability.

The main purpose of Fenkarol is to reduce the effect of histamine, which is responsible for the development of an allergic reaction. It selectively blocks receptors and activates the production of the enzyme diamine oxidase, which can break down and remove histamine.

After taking the tablets, spasms in the intestines are relieved, itching sensations and skin rashes characteristic of allergies disappear.

At the same time, the medication does not inhibit the functioning of the central nervous system.

The effect of intramuscular administration is achieved after 30 minutes, taking tablets - after 60 minutes.

Indications for use of Fenkarol

To treat allergies, tablets or an injection solution are used (severe course, urgent need).

What are Fenkarol tablets for?

From hay fever , urticaria , food or medication , hay fever , and other allergic diseases.

Also indications for the use of Fenkarol are:

  • dermatosis ( skin itch , eczema , neurodermatitis );
  • rhinopathy , which is allergic in nature;
  • angioedema;
  • reactions to an allergen accompanied by bronchospasm.

How does Fenkarol for children (10 mg) work?

An allergic reaction and all its manifestations (runny nose, itching, etc.) appear as a result of the formation of a substance such as histamine in the body.
The medicine blocks the receptors with which histamine tries to interact and stops the development of allergies at the very beginning. The drug begins to act within half an hour after administration. What is it used for?

For the treatment of any type of allergy. From insect bites to dermatitis and hay fever. It is not addictive and can be taken for 3 weeks without interruption.

What is treated with Fenkarol?

  • Hay fever (hay fever)
  • Acute and chronic urticaria
  • Food allergies
  • Rhinoconjunctivitis
  • Skin itching, dermatitis, eczema, neurodermatitis
  • Drug-induced allergies
  • Allergic rhinitis
  • Insect bites
  • Allergic conjunctivitis

Side effects

Side effects are very rare.

If the patient is particularly sensitive to the effects of quifenadine, the following may occur:

  • dry mouth and mucous membranes;
  • indigestion and bitter taste in the mouth;
  • nausea and vomiting;
  • mild sedative effect ( drowsiness , lethargy );
  • headache and loss of consciousness .

If you have gastrointestinal diseases, the likelihood of side effects increases.

If you have any of the above reactions or if new ones occur, you should consult your doctor.

Reviews

Most reviews of Fenkarol are positive. The drug quickly helps with swelling and bronchospasm that occurs due to an allergic reaction, insect bites and hypersensitivity to certain foods. There is good tolerability and no side effects, including in children.

According to experts, the medication does not cause drowsiness or addiction, and is good for treating chickenpox and urticaria. ENT doctors prescribe Fenkarol for swelling of the nasal mucosa after surgery, for adenoiditis and sinusitis.

Instructions for use of Fenkarol (Method and dosage)

If necessary, the appropriate dosage form (tablets or injection solution) and dosage should be used, depending on age, symptoms and adverse reactions.

The tablets are taken after meals with water or other liquid.

Instructions for Fenkarol, 25 mg

Prescribed, as a rule, to adults. 1-2 tablets, 3 or 4 times a day. You can take no more than 200 mg of the drug per day.

For children over 12 years of age, the daily dosage is 50-75 mg, respectively, 1 tablet, in 2-3 doses.

The duration of treatment is from 10 to 20 days.

Instructions for children's Fenkarol (dosage 10 mg)

Inside, orally.

  • Children aged 3 to 7 years are prescribed one tablet 2 times a day;
  • Ages 7 to 12 – 1 tablet, 2 or 3 times a day;
  • For children over 12 years old – 2 tablets 2-3 times a day.

The course of treatment must be agreed with your doctor. Ranges from 10 days to half a month.

Instructions for solution for intramuscular administration

For hay fever , intramuscular injections of 2 ml are prescribed, 2 times a day, for 3 days. Then the dosage is reduced to 2 ml per day for 2 days.

For Quincke's edema or urticaria, for the first 5 days, injections of 2 ml are given, 2 times a day. Then another 3 days, 2 ml per day.

A maximum of 20 mg (2 ml) of the drug can be administered per injection, and a maximum of 40 mg per day.

If the acute allergic reaction has been stopped, then switching to the tablet form is recommended.

In what forms is it produced, composition

Fenkarol has two dosage forms:

  • white tablets in the shape of a flat cylinder with dosages of 10, 25 and 50 mg of the active ingredient;
  • a transparent solution without a specific odor for injections into the muscle, 1 ml contains 10 mg of the main substance.

All varieties of the drug contain quifenadine as the main substance.

The solution additionally contains glutamic acid and water for injection. The tablets contain sucrose, modified potato and corn starches, and calcium stearate.

The tablets are packaged in contour packages with cells of 10 or 15 pieces, one box contains 20 or 30 tablets and instructions.

The solution is packaged in glass ampoules of 1 or 2 ml. One package contains 10 ampoules in a cell plate and instructions.

Analogs

Level 4 ATX code matches:
Dezal

Histaphene

Clarisens

Telfast

Erius

Claridol

Claritin

Loratadine

Fexofast

Peritol

Desloratadine

LauraHEXAL

Clarotadine

Rupafin

Ciel

Dramamine

Lordestin

Lomilan

Kestin

Loratek

Analogues of Fenkarol: Alerik , Alersis , Alergomax , Alernova , Alergostop Gistafen , , Kestin , Ketotifen , Laurent , Loratadine , Lordes , Lorizan , Semprex , Tigofast , Fexomax , Fexofen - Sanovel , Edem , Erius , Erolin , Eridez , Fribris , Fexofast , Trexil Neo , Telfast , Peritol , Lorano ODT , Claritin , Altiva .

Instructions for medical use of the drug FENKAROL® 25 mg tablets

Trade name of the drug

FENKAROL® 25 mg tablets

International nonproprietary name: quifenadinum (quifenadine).

Composition of the drug

One tablet contains: Active ingredient - hifenadine hydrochloride 25 mg; excipients - sugar, potato starch, calcium stearate.

Release form

Tablets, dosage 25 mg.

general characteristics

Flat-cylindrical tablets with a chamfer, white or almost white.

Pharmacotherapeutic group and ATC code

Other antihistamines for systemic use. ATX code: R06AX31

Pharmacological properties

Fenkarol is an antihistamine that reduces the effect of histamine on organs and their systems. Unlike other classical drugs in this group, Fenkarol has a special mechanism of action: the drug blocks histamine H-1 receptors in peripheral tissues, and also activates the enzyme diamine oxidase (histaminase), thus reducing the content of histamine in tissues. This explains the effectiveness of Fenkarol for patients whose treatment with other antihistamines is ineffective.

Fenkarol is quickly absorbed from the gastrointestinal tract and is found in body tissues within 30 minutes. The maximum concentration of the active substance in the blood plasma is reached after an hour. Fenkarol is metabolized in the liver. Metabolites of Fenkarol and the unchanged portion of the drug are excreted mainly in urine and bile within 48 hours.

Indications for use

Children and teenagers over 12 years old and adults

Hay fever, acute and chronic urticaria, allergic rhinitis, allergic conjunctivitis, angioedema, allergic skin diseases (atopic dermatitis, eczema), skin itching (against the background of hyperparathyroidism, in the active phase of hepatitis), allergic reactions associated with taking medications or foods .

Directions for use and doses

Fenkarol is taken orally immediately after meals.

Adults are prescribed 25-50 mg 2-4 times a day. The maximum daily dose is 200 mg.

Children over 12 years old - 25 mg 2-3 times a day.

The duration of treatment is 10-20 days. If necessary, the course is repeated.

It is not recommended to use Fenkarol 25 mg tablets in children under 12 years of age (high content of active substance per dosage unit). Children under 12 years of age should use Fenkarol 10 mg tablets.

If you miss a dose, take the medicine as soon as you remember, but skip it if it is already time for your next dose. Never take double doses.

Side effects

Classification of undesirable side reactions by frequency of development: very often (up to 1/10); often (from 1/100 to <1/10); uncommon (from 1/1000 to <1/100); rare (1/10,000 to <1/1000); very rare (less than 1/10,000).

Nervous system disorders: uncommon - headache, drowsiness,

Gastrointestinal disorders: often - dry mouth; infrequently, dyspeptic disorders (nausea, vomiting), which usually disappear when the dose is reduced or the drug is discontinued.

If side effects occur, especially those that are not listed in the package insert, you should consult a doctor.

Contraindications

  • Hypersensitivity to the active substance and/or any of the auxiliary components of the drug.
  • The first three months of pregnancy. In the second and third trimesters of pregnancy - not recommended.
  • Breast-feeding.

Overdose

If you suspect an overdose, call a doctor immediately.

Symptoms: taking high doses of the drug can cause dry mucous membranes, headache, vomiting, epigastric pain and dyspeptic symptoms.

Treatment: it is necessary to provide symptomatic and supportive therapy for the vital functions of the body. There is no specific antidote.

Precautionary measures

Use with caution in severe diseases of the cardiovascular system, gastrointestinal tract, liver and/or kidneys.

Fenkarol does not have a depressant effect on the central nervous system, but in some cases a weak sedative effect is observed.

The medicinal product contains sugar, so if you are intolerant to any sugars, consult your doctor before using this medicinal product.

Use during pregnancy and lactation

In the first three months of pregnancy, the use of the drug is contraindicated. In the second and third trimester - not recommended.

It is not known whether the drug is excreted in breast milk, therefore breastfeeding while using the drug is contraindicated.

Impact on the ability to drive vehicles

Persons whose work requires a quick physical or mental reaction (transport drivers, etc.) should first determine (by short-term prescription) whether the drug has a sedative effect. Persons who exhibit sedative effects are not recommended to drive a vehicle or operate dangerous machinery.

Interaction with other drugs

Fenkarol does not enhance the inhibitory effect of alcohol and hypnotics on the central nervous system (CNS). Fenkarol has weak M-cholinergic blocking properties, but with a decrease in gastrointestinal motility, the absorption of slowly absorbed medications may increase (for example, indirect anticoagulants - coumarins).

Best before date

5 years. Do not use the medicine after the expiration date.

Storage conditions

In a place protected from moisture and light at a temperature not exceeding 25 o C. Keep out of the reach of children.

Package

Tablets of 10 pieces are packed in blisters made of polyvinyl chloride film and varnished aluminum foil. 2 blisters (20 tablets) together with instructions (leaflet) for medical use are placed in a cardboard pack.

Conditions for dispensing from pharmacies

Dispensed without a doctor's prescription.

Information about the manufacturer (applicant)

JSC "Olainfarm" Address: st. Rupnicu 5, Olaine, LV-2114, Latvia.

Reviews about Fenkarol

Mostly people leave good reviews about Fenkarol. The product helps with severe bronchospasms, relieves swelling during bronchitis, acute respiratory infections and runny nose . The drug is inexpensive and effective. However, adverse reactions may occur, most often nausea and bitterness in the mouth.

Reviews of Fenkarol for children on the Internet

On various forums, people write that Fenkarol is a fast-acting and effective medicine that is generally well tolerated; there are reports of adverse reactions.

The medicine is not suitable for children under one year of age; some consider this a disadvantage.

Indications for use

The instructions for Fenkarol contain a list of conditions for which the drug can help. Tablets and injections are prescribed by allergists and dermatologists for:

  • manifestations of hay fever;
  • runny nose of allergic origin;
  • urticaria in acute and chronic form;
  • angioedema;
  • dermatoses (eczema, psoriasis, atopic dermatitis);
  • skin itching;
  • drug or food allergies.

Price, where to buy

The price of Fenkarol in tablets is 153 rubles, for 20 pieces, 10 mg each.

The cost of the same amount, but with a dosage of 25 mg, is about 220 rubles.

It is currently difficult to find out the price of Fenkarol in ampoules.

  • Online pharmacies in RussiaRussia
  • Online pharmacies in UkraineUkraine
  • Online pharmacies in KazakhstanKazakhstan

ZdravCity

  • Fenkarol tablets 50 mg 15 pcs. Olainfarm JSC
    348 rub. order

Pharmacy Dialogue

  • Fenkarol tablets 25 mg No. 20Olainfarm OA

    RUR 492 order

  • Fenkarol tablets 10 mg No. 20Olainfarm OA

    RUB 251 order

  • Fenkarol tablets 50 mg No. 15Olainfarm OA

    RUB 421 order

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Pharmacy24

  • Fenkarol 25 mg No. 20 tablets AT "Olainfarm", Latvia
    150 UAH. order
  • Fenkarol 50 mg No. 30 tablets AT "Olainfarm", Latvia

    303 UAH. order

  • Fenkarol 10 mg No. 20 tablets AT "Olainfarm", Latvia

    101 UAH order

PaniPharmacy

  • Fenkarol tablets Fenkarol tablets. 0.010g No. 20 Latvia, Olainfarm JSC

    90 UAH order

  • Fenkarol tablets Fenkarol tablets. 50 mg No. 30 Latvia, Olainfarm JSC

    302 UAH. order

  • Fenkarol tablets Fenkarol tablets. 25 mg No. 20 Latvia, Olainfarm JSC

    162 UAH order

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How to give Fenkarol to children?

Any antihistamines for children should be given with extreme caution:

  • strictly follow the dosage;
  • do not violate the regimen;
  • make sure the tablets are not expired.

Find Fenkarol 10 mg in your city's pharmacy

Important! Before giving allergy medicine to a baby, you need to crush it into powder and dilute it in a small amount of water at room temperature.

Finding and buying Fenkarol for children in Minsk and other cities of Belarus is not difficult; you can go to any nearby pharmacy near your home. You can find out the price of Fenkarol in advance at the help desk.

Instructions for use of the drug Fenkarol 10 mg tablets

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