Description of the drug
Flemoxin Solutab is a popular representative of the group of semi-synthetic penicillins with a broad spectrum of action. It has established itself as an effective new generation drug with high efficiency. Manufacturer – Netherlands.
The main active ingredient is amoxicillin. Excipients include cellulose, vanillin, crospovidone, magnesium stearate, saccharin and flavorings.
Available in the form of oval tablets with a score for ease of breaking in half, they easily dissolve in water.
Due to the different concentrations of the main active ingredient, Flemoxin Solutab 125, 250, 500 and 1000 mg is available in pharmacies. The package contains 20 tablets and instructions for use.
The antibiotic is active against most strains of streptococci, staphylococci, enterococci, and also helps against diseases caused by gonococci, meningococci, Proteus and Listeria.
When taken together with metronidazole, it is active against Helicobacter pylori.
According to the instructions for use of Flemoxin Solutab, tablets should be stored at air temperatures up to 25°C for 5 years from the date of issue.
Flemoxin solutab 125 mg n20 dispersible tablets
Latin name
Flemoxin Solutab
Active ingredient: Amoxicillin (Amoxicillin)
Compound
The composition of dispersible (water-soluble) tablets includes amoxicillin in the form of amoxicillin trihydrate, microcrystalline and dispersible cellulose, vanillin, crospovidone, flavors (lemon and tangerine), magnesium stearate, saccharin.
Release form
Flemoxin Solutab dispersible tablets:
125, 250, 500 or 1000 mg package No. 20 (blisters of 5 pcs., 4 blisters per package);
125 mg package No. 14 (blisters of 7 pcs., 2 blisters per package).
The tablets are oval, white or white with a yellowish tint, with a dividing line on one side, and a digital designation (231, 232, 234 and 236) and the manufacturer’s logo on the other.
pharmachologic effect
Antibacterial, bactericidal.
Pharmacodynamics and pharmacokinetics
Amoxicillin is a semisynthetic β-lactam antibiotic of the penicillin group with a wide spectrum of antimicrobial activity.
The bactericidal properties of the drug are due to the ability to suppress transpeptidase, disrupt the production of peptidoglycan (supporting protein of cell walls) during periods of division and growth, and provoke the lysis of microorganisms.
Shows activity against Gram (+) aerobes, including Staphylococcus spp. (with the exception of penicillinase-producing strains) and Streptococcus spp. (including Str.pneumoniae and faecalis); Gram (-) aerobes (gonococci, meningococci, Escherichia coli and Haemophilus influenzae, Proteus mirabilis; certain strains of Klebsiella, Shigella and Salmonella, as well as against H. pylori.
Ineffective against strains of Proteus P. rettgeri and vulgaris (they are indole-positive), serrations, pseudomonads, enterobacteria, Morganella morgani. Mycoplasma, rickettsia and viruses are resistant to amoxicillin.
A feature of the dosage form is that the tablets are easily dispersed in water to form a dispersion. Thanks to this, the drug is quickly and as completely as possible (more than 93% of the dose taken) absorbed from the digestive canal.
Eating does not affect the absorption of the substance. TCmax - ranging from 60 to 120 minutes. When taking dispersible tablets, the plasma concentration of amoxicillin is higher than when taking insoluble forms of the drug. The active substance is resistant to acids.
TCmax when taking 500 mg amoxicillin is 120 minutes. When taking twice as much or half as much of the drug, Cmax also changes by half.
About 20% of the administered amoxicillin dose is bound to plasma proteins. The substance in therapeutically effective concentrations penetrates well into bone tissue, mucous membranes, sputum and intraocular fluid. Its concentration in bile is 2-4 times higher than plasma concentration, in amniotic fluid - from 25 to 30% of plasma concentration in the body of a pregnant woman.
Amoxicillin passes through the BBB poorly, but in case of inflammation of the meninges, its concentration in the cerebrospinal fluid is about 1/5 of the plasma concentration.
The substance is partially metabolized; most metabolic products are inactive against pathogenic microflora.
Excretion is carried out by the kidneys. In patients with healthy kidneys, T1/2 - from 60 to 90 minutes, in children under six months of age (including premature babies and newborns) - from 3 to 4 hours. If liver function is impaired, the indicator does not change; if kidney function is impaired, it can increase to 8.5 hours (this is T1/2 of amoxicillin for anuria).
Indications for use
- bacterial infections of the external respiratory system (angina, pneumonia, bronchitis, pharyngitis, sinusitis, acute inflammation of the middle ear), genitourinary system (pyelonephritis, pyelitis, cystitis, urethritis, cervicitis, endometritis), skin and/or soft tissues (impetigo, erysipelas, secondary infected dermatoses), digestive system organs and abdominal infections (angiocholitis, peritonitis, typhoid fever, cholecystitis, salmonellosis, dysentery, salmonella carriage), if they are caused by bacteria sensitive to Flemoxin.
Flemoxin - what is it used for in pediatrics?
Flemoxin Solutab is the drug of the penicillin group most commonly used in pediatric practice. Most often it is prescribed for bacterial infections of the respiratory system.
Practical experience proves the high effectiveness of Flemoxin for sinusitis, acute non-purulent otitis, bronchitis, bronchopneumonia, tonsillitis, and sore throat.
The drug is safe, well tolerated by young patients of any age and, just as important when it comes to treating children, has excellent organoleptic properties.
Contraindications
Flemoxin is not prescribed for hypersensitivity to amoxicillin, other β-lactams or auxiliary components of the tablets.
Relative contraindications for the antibiotic Flemoxin Solutab:
lymphocytic leukemia;
Infectious mononucleosis;
renal failure;
history of gastrointestinal pathology (especially colitis associated with the use of antibiotics);
pregnancy;
lactation;
breastfeeding period;
polyvalent hypersensitivity to chemicals foreign to the body (xenobiotics).
Side effects
Side effects appear as:
nausea, changes in taste, diarrhea, vomiting, moderate increases in liver enzyme activity (sometimes), hemorrhagic and pseudomembranous colitis (extremely rare);
interstitial nephritis (extremely rare);
hemolytic anemia, neutropenia, agranulocytosis, thrombocytopenia.
When using the drug in the form of dispersible tablets, no adverse effects from the nervous system were observed.
The use of the drug may be accompanied by the development of hypersensitivity reactions, which are expressed in the form of a rash (mainly specific maculopapular), exudative erythema multiforme (rarely), angioedema and anaphylactic shock (in exceptional cases).
Instructions for use
How should adults take Flemoxin tablets?
The drug is taken orally, without reference to the time of meal.
The tablet can be dissolved in 20 ml of water to obtain a syrup or in 100 ml of water to obtain a suspension; it can be swallowed whole or taken in crushed form.
For mild and moderately severe infections, 250 mg tablets are taken in 2-3 pieces. 2 times a day, 500 mg tablets - 1-1.5 pcs. 2 r./day, 1000 mg tablets - half 3 r./day.
When treating severe diseases, as well as infections with hard-to-reach foci, it is preferable to take the drug three times a day.
The daily dose of antibiotic for severe infections, relapses and chronic pathologies is 1.5-2 tablets. 500 mg 3 times/day.
For acute gonorrhea without complications, a single dose of Flemoxin with Probenecid is indicated (dose, 3 and 1 g, respectively).
For severe infections and chronic pathologies, the treatment regimen is selected taking into account the characteristics of the clinical picture of the disease.
In case of kidney damage, in which the Clcr value is in the range from 15 to 40 ml/min, the interval between tablet doses should be increased to 12 hours. If Clcr does not exceed 10 ml/min, the dosage of amoxicillin should be reduced by 15-50%. For anuria, the highest daily dose of amoxicillin is 2 g.
How should children take Flemoxin tablets?
Children's Flemoxin is a tablet with a dosage of amoxicillin of 125 and 250 mg. The instructions for children indicate that it is more convenient for a younger child to give a syrup or suspension; older children can swallow the tablet whole or after chewing it.
Instructions for use
Flemoxin for children over 10 years of age is similar to the instructions for adults: for mild and moderately severe infections, the child is given 3-4 tablets. 125 mg 3 times/day.
Flemoxin Solutab for children over 3 years of age is prescribed to take 3 tablets. 125 mg 2 times/day. or 2 tablets. 125 mg 3 times/day.
For children under 3 years of age, according to the instructions for use, Flemoxin Solutab 125 mg, two tablets given 2 times a day. or one 3 rubles/day.
The dosage of Flemoxin Solutab for children, which contains 250 mg of amoxicillin, is as follows:
2-3 tab. 2 rubles/day — patients over 10 years of age;
1 tab. 3 rubles/day — patients 3-10 years old;
1 tab. 2 rubles/day or 0.5 tab. 3 rubles/day - patients under three years of age.
The daily dose of Flemoxin Solutab for children of all age groups (including children of the first year of life) is from 30 to 60 mg/kg, divided into 2 or 3 doses. If the disease is severe or the pathological focus is difficult to reach, it is preferable to take the drug 3 times a day.
For severe infections (including those with hard-to-reach lesions), the recommended dose of antibiotic is 60 mg/kg/day, divided into three doses.
Duration of treatment
The duration of the course for mild and moderately severe infections is from 5 days to 1 week. If the causative agent of the infection is Str. pyogenes, treatment lasts at least 10 days.
For severe infections, medication should be continued for 48 hours after symptoms disappear.
Antibiotic Flemoxin Solutab for sore throat
Sore throat is a common acute infectious disease, the local manifestations of which are damage to the tonsils (mainly the first and second tonsils). The most common causative agents of sore throat are B-hemolytic streptococci of group A. Staphylococci provoke it much less often.
Untreated or undertreated tonsillitis is complicated by paratonsillitis, nephritis, myocarditis, paratonsillar abscess, and tonsillogenic sepsis.
Given the bacterial nature of the disease, timely use of antibiotics is very important. If in case of catarrhal tonsillitis, in some cases, local antibiotics are enough for the patient, then in case of follicular and lacunar tonsillitis, the doctor must prescribe systemic drugs.
Research results and practical experience have shown that the most effective remedies for angina are drugs of the penicillin group.
The advantages of Flemoxin over analogues are:
unique dosage form (Solyutab);
the presence of tablets with a “children’s” dosage of the active substance;
the possibility of using the drug without being tied to the time of meals.
For adults with sore throat, it is recommended to take the drug 2 times a day. 500-700 mg each. For angina in children, children's Flemoxin Solutab is used - tablets with a minimum dosage of the active substance. The dose is selected by the doctor depending on the patient’s age and the characteristics of the disease.
After the symptoms of sore throat are relieved (body temperature decreases, pustules on the tonsils disappear, sore throat goes away, the condition of the lymph nodes normalizes), taking Flemoxin should be continued for at least two more days.
If treatment is stopped immediately, the risk of disease recurrence is high. Moreover, the symptoms may appear with a vengeance.
Use of the drug for sinusitis
Sinusitis is an inflammation of the paranasal sinuses.
The use of an antibiotic for sinusitis is advisable if the disease is caused by bacteria sensitive to its action. When associated with a viral or fungal infection, as well as allergic sinusitis, antibiotic therapy is not only ineffective, but can also aggravate the course of the disease.
Acute bacterial sinusitis manifests itself first:
hyperthermia (febrile temperature or higher);
violation of nasal respiration and phonation;
soreness and swelling of the skin in the projection of the maxillary cavities;
decreased sense of smell;
the presence of pain radiating to different parts of the face (the pain gradually loses its specific location);
symptoms of general intoxication (sleep disturbances, headache, joint pain, etc.);
the characteristic color of the pathological secretion discharged from the sinuses (its color in bacterial infections usually varies from yellow to dark green).
The selection of an antibiotic is carried out taking into account:
the results of a microbiological study of biomaterial taken from the paranasal sinuses and a rapid test for staining of the pathogen using the Gram method;
characteristics of the patient’s body;
possible allergic reactions to the drug;
presence of concomitant diseases.
If the cause of the disease is staphylococci, streptococci or Haemophilus influenzae, it is considered most preferable to prescribe drugs of the penicillin group to the patient.
The use of amoxicillin for bacterial sinusitis (including complicated forms of the disease) gives a pronounced positive effect already in the first 7 days of treatment: the patient’s symptoms of intoxication and pain in the paranasal sinuses decrease/disappear, the temperature decreases and nasal breathing becomes easier.
The effectiveness of Flemoxin Solutab is explained by the fact that this drug:
affects a large number of strains of infectious agents;
quickly and in high concentrations absorbed from the digestive tract;
resistant to gastric juice;
Available in an easy-to-use form.
Overdose
Symptoms
overdose of Flemoxin Solutab: nausea, diarrhea, vomiting, water-salt imbalance.
Treatment:
gastric lavage, prescribing enterosorbents, saline laxatives, taking measures aimed at correcting the balance of water and electrolytes.
Interaction
Phenylbutazone, probenecid, oxyphenbutazone and, to a slightly lesser extent, sulfinpyrazone and ASA inhibit the secretion of penicillin antibiotics, which leads to an increase in T1/2 and an increase in the plasma concentration of amoxicillin.
Bactericidal antibiotics (including rifampicin, vancomycin, cephalosporins and aminoglycosides) have a synergistic effect when used in combination with Flemoxin.
When taken simultaneously with certain bacteriostatic agents (sulfonamides, chloramphenicol, etc.), antagonism is possible.
Use with estrogen-containing oral contraceptives may reduce the effectiveness of the latter and increase the risk of recurrent bleeding.
Use in combination with allopurine, unlike the combination of Ampicillin with allopurine, does not increase the frequency of skin reactions.
Terms of sale
On prescription.
Storage conditions
Store at temperatures below 25°C.
Best before date
Five years.
Indications for the use of Flemoxin Solutab
Flemoxin Solutab is widely used in therapeutic and pediatric practice.
Indicated if bacterial sensitivity to amoxicillin is detected in:
- Bacterial sore throat, pharyngitis, sinusitis, laryngitis, otitis media, tracheitis.
- Infections in the bronchi and pneumonia).
- Infection of the urinary organs (cervicitis, urethritis, cystitis, pyelonephritis, endometritis).
- Skin infections (dermatoses, erysipelas, impetigo).
- Bacterial damage to the digestive organs and peritoneum (salmonellosis, dysentery, typhoid fever).
For exacerbations of chronic gastritis and gastric ulcers caused by bacteria, it is prescribed with metronidazole.
Children are prescribed antibiotics for the same indications as adults.
Contraindications and side effects
Particular sensitivity to amoxicillin and the components of the drug is an obstacle to the use of Flemoxin. It is also contraindicated for:
- Infectious mononucleosis.
- Kidney failure.
- Lymphocytic leukemia.
- Severe pathologies of the gastrointestinal tract, especially with colitis caused by the use of antibiotics.
- Pregnancy (possibly with caution as prescribed by a doctor).
- Viral infections.
- Bronchial asthma.
Use during lactation is allowed with caution.
The use of Flemoxin may cause undesirable effects, such as:
- Attacks of nausea.
- The appearance of diarrhea.
- Hemorrhagic colitis.
- Interstitial nephritis.
- Neutropenia, thrombocytopenia.
- An allergic reaction in the form of a rash, and in rare cases, anaphylactic shock or angioedema.
Flemoxin solutab 1000 mg n20 dispersible tablets
Release form
Dispersible tablets.
Package
20 pcs.
pharmachologic effect
A broad-spectrum penicillin antibiotic that is destroyed by penicillinase.
Indications
Infectious and inflammatory diseases caused by microorganisms sensitive to the drug:
- respiratory infections;
- infections of the genitourinary system;
— infections of the gastrointestinal tract;
- infections of the skin and soft tissues.
Contraindications
- hypersensitivity to the components of the drug;
- hypersensitivity to other beta-lactam antibiotics, incl. to other penicillins, cephalosporins, carbapenems.
Carefully
the drug should be used for polyvalent hypersensitivity to xenobiotics, infectious mononucleosis, lymphocytic leukemia, a history of gastrointestinal diseases (especially with colitis associated with the use of antibiotics), renal failure, during pregnancy and lactation, allergic reactions (including a history of ).
Use during pregnancy and breastfeeding
The use of Flemoxin Solutab® during pregnancy and lactation is possible if the expected benefit of therapy for the mother outweighs the risk of side effects in the fetus and infant.
Amoxicillin is excreted in small quantities into breast milk, which can lead to the development of sensitization phenomena in an infant.
special instructions
The drug should be prescribed to patients with infectious mononucleosis and lymphocytic leukemia with caution, since there is a high probability of exanthema of non-allergic origin.
A history of erythroderma is not a contraindication for the use of Flemoxin Solutab®.
Cross-resistance with penicillin drugs and cephalosporins is possible.
The appearance of severe diarrhea, characteristic of pseudomembranous colitis, is an indication for discontinuation of the drug.
During a course of treatment, it is necessary to monitor the state of the function of the hematopoietic organs, liver and kidneys.
Superinfection may develop due to the growth of microflora insensitive to the drug, which requires a corresponding change in antibacterial therapy.
When treating mild diarrhea during a course of treatment, antidiarrheal drugs that reduce intestinal motility should be avoided; You can use kaolin- or attapulgite-containing antidiarrheal drugs. Treatment must continue for another 48-72 hours after the disappearance of clinical symptoms of the disease.
When using estrogen-containing oral contraceptives and amoxicillin simultaneously, other or additional methods of contraception should be used, if possible.
Impact on the ability to drive vehicles and operate machinery
There were no reports of adverse effects of the drug on the ability to drive vehicles or operate machines.
Compound
Amoxicillin trihydrate 1.1655 g, which corresponds to the content of amoxicillin 1 g.
Excipients: dispersible cellulose - 34.8 mg, microcrystalline cellulose - 50.5 mg, crospovidone - 50.4 mg, vanillin - 1 mg, tangerine flavor - 9.1 mg, lemon flavor - 11.1 mg, saccharin - 13.1 mg, magnesium stearate - 6 mg.
Directions for use and doses
The drug is taken orally. The drug is prescribed before, during or after meals. The tablet can be swallowed whole, divided into pieces or chewed with a glass of water, and can also be diluted in water to form a syrup (20 ml) or suspension (100 ml), which has a pleasant fruity taste.
The dosage regimen is set individually, taking into account the severity of the disease, the sensitivity of the pathogen to the drug, and the age of the patient.
In the case of infectious and inflammatory diseases of mild to moderate severity, it is recommended to use the drug according to the following scheme: adults and children over 10 years of age are prescribed 500-750 mg 2 times / day or 375-500 mg 3 times / day; children aged 3 to 10 years are prescribed 375 mg 2 times / day or 250 mg 3 times / day; children aged 1 to 3 years are prescribed 250 mg 2 times a day or 125 mg 3 times a day.
The daily dose of the drug for children (including children under 1 year old) is 30-60 mg/kg/day, divided into 2-3 doses.
When treating severe infections, as well as for hard-to-reach foci of infection (for example, acute otitis media), a three-time dose is recommended.
For chronic diseases, recurrent infections, severe infections, adults are prescribed 0.75-1 g 3 times a day; children - 60 mg/kg/day, divided into 3 doses.
For acute uncomplicated gonorrhea, 3 g of the drug is prescribed in 1 dose in combination with 1 g of probenecid.
Patients with impaired renal function with CC
In case of mild to moderate infections, the drug is taken for 5-7 days. However, for infections caused by Streptococcus pyogenes, the duration of treatment should be at least 10 days.
The drug must be continued for 48 hours after the symptoms of the disease disappear.
Side effects
From the digestive system:
rarely - changes in taste, nausea, vomiting, diarrhea, dysbacteriosis, stomatitis, glossitis; in some cases - a moderate increase in the activity of liver transaminases, cholestatic jaundice, hepatic cholestasis, acute cytolytic hepatitis, pseudomembranous and hemorrhagic colitis.
From the urinary system:
development of interstitial nephritis, crystalluria.
From the hematopoietic system:
leukopenia, neutropenia, thrombocytopenic purpura, eosinophilia, thrombocytopenia, agranulocytosis, hemolytic anemia.
From the nervous system:
agitation, anxiety, insomnia, ataxia, confusion, behavior changes, depression, peripheral neuropathy, headache, dizziness, epileptic seizures.
Allergic reactions:
skin reactions, mainly in the form of a specific maculopapular rash, urticaria, skin hyperemia, erythematous rashes, rhinitis, conjunctivitis, exudative erythema multiforme (Stevens-Johnson syndrome), fever, arthralgia, eosinophilia, exfoliative dermatitis, reactions similar to serum disease, toxic epidermal necrolysis, allergic vasculitis, acute generalized exanthematous pustulosis; in some cases - anaphylactic shock, angioedema.
Other:
difficulty breathing, vaginal candidomycosis, superinfection (especially in patients with chronic diseases or reduced body resistance).
Drug interactions
Probenecid, phenylbutazone, oxyphenbutazone, diuretics, allopurinol, NSAIDs, and to a lesser extent, acetylsalicylic acid and sulfinpyrazone suppress the tubular secretion of penicillins, which leads to an increase in T1/2 and an increase in the concentration of amoxicillin in the blood plasma.
Bactericidal antibiotics (including aminoglycosides, cephalosporins, vancomycin, rifampicin) exhibit synergism when taken simultaneously.
Antagonism is possible when taken with some bacteriostatic drugs (for example, chloramphenicol, sulfonamides).
Concomitant use of amoxicillin with estrogen-containing oral contraceptives may reduce the effectiveness of the latter and increase the risk of acyclic bleeding.
Antacids, glucosamine, laxatives, aminoglycosides, and food reduce absorption. Ascorbic acid increases absorption.
Increases the effectiveness of indirect anticoagulants (suppressing intestinal microflora, reduces the synthesis of vitamin K and the prothrombin index); enhances the absorption of digoxin.
Concomitant use of amoxicillin with allopurinol increases the risk of developing skin rash.
Overdose
Symptoms:
gastrointestinal dysfunction - nausea, vomiting, diarrhea; Vomiting and diarrhea may result in water and electrolyte imbalance.
Treatment:
Gastric lavage, activated charcoal, and saline laxatives are prescribed; measures are taken to maintain water and electrolyte balance, hemodialysis.
Storage conditions
The drug should be stored out of the reach of children at a temperature not exceeding 25°C.
Best before date
5 years.
How to use Flemoxin Solutab
The tablet is taken orally, at any time, regardless of meals. It can be dissolved in water (a tablespoon or 100 ml) or crushed to make it easier to swallow.
It is not recommended to take the antibiotic with juice or tea, as this may change the pharmacological properties of the drug.
The prescribed dose of medication depends on the condition and age of the patient.
Instructions for use of Flemoxin Solutab 500 mg provide for different tablet dosage regimens.
A single dose of amoxicillin for adult patients and children over 10 years of age (body weight more than 40 kg) with mild to moderate severity is 250-500 mg. If the condition is severe, then the dose is increased to 1 g. For children aged 5-10 years, 250 mg is enough at a time. Children 2-5 years old – 125 mg.
Thus, treatment regimens may be as follows:
- Children 1-3 years old: 1 tablet 125 mg three times a day (or half a tablet 250 mg). The doctor may prescribe a dosage of 250 mg twice daily depending on the patient's condition.
- Child 3-10 years old: 1 tablet 250 mg three times a day. The pediatrician may also prescribe a dosage of 375 mg twice a day.
- Patient over 10 years old: 375-500 mg Flemoxin three times a day or 500-750 mg twice a day.
The average daily dose of medication for children is determined based on the calculation of 30 mg per 1 kg of body weight, it is divided into 2-3 doses. If the course of the disease is severe or the infection is in hard-to-reach places, then, as a rule, 3 doses are recommended. In this case, you need to wait 8 hours between taking the pills and try to take them at the same time.
The course of treatment is determined by the doctor and is at least 5-7 days. If the disease is caused by streptococci, then the antibiotic Flemoxin is taken for 10 days. It is impossible to stop taking it at the first signs of improvement, as a relapse is possible due to incomplete death of the infectious pathogen.
With the correct dosage and regular use, a noticeable effect of treatment occurs within 2-3 days. If there is no positive dynamics, laboratory tests are carried out, and the antibiotic is replaced with another.
Flemoxin Solutab
Antibiotics of the penicillin group and, in particular, amoxicillin, are highly effective drugs for the treatment of bacterial infections of the respiratory tract, because extend their activity to a fairly wide range of pathogens. This is, in fact, a well-known fact. The original drug based on amoxicillin, Flemoxin Solutab (hereinafter referred to as Flemoxin) from a Dutch pharmaceutical company is of particular interest: in addition to a wide spectrum of antibacterial action, it has very worthy pharmacokinetic and pharmacodynamic characteristics (bioavailability, absorption, etc.) against the general background, which together with a unique dosage form - dispersible (soluble) tablets with apricot flavor - makes it popular among various age groups. Today, flemoxin is a first-line antibiotic in the treatment of acute infectious and inflammatory diseases of the ear/nose/throat and lower respiratory tract.
Flemoxin has a bactericidal effect against such gram-positive and gram-negative bacteria as Streptococcus pneumonia, Streptococcus pyogenes, Clostridium tetani, Neisseria meningitidis, Neisseria gonorrhoeae, Staphylococcus aureus (not producing the enzyme beta-lactamase), Listeria monocytogenes, Bacillus anthracis, Helicobacter pylori. Under certain conditions, the drug can be effective against Escherichia coli, Enterococcus faecalis, Salmonella typhi, Proteus mirabilis, Shigella sonnei, Vibrio cholerae.
Taking flemoxin does not make sense for infections caused by bacteria that produce beta-lactamases, as well as Pseudomonas spp., indole-positive Serratia spp., Proteus spp., Enterobacter spp.
Flemoxin is stable in the acidic environment of the stomach. When taken orally, it is absorbed and distributed in the body very quickly, regardless of food intake. Available only in the form of dispersible tablets, which can be swallowed, divided into pieces or chewed with water. As for the main method of using flemoxin tablets - dissolution, water is used for this in a volume of 20 ml (the final product is syrup) or 100 ml (suspension). According to general recommendations, adults and children over 10 years of age use 500-750 mg of the drug twice or 375-500 mg three times a day. The specifics of using the drug for specific diseases, as well as in young children, can be found in the package insert. The duration of antibiotic therapy for mild and moderate infections is about 5-7 days, and in cases of infections caused by Streptococcus pyogenes - 10 days. The disappearance of clinical manifestations of the disease is by no means a signal for immediate discontinuation of the drug: it should be taken for another 2 days. If the use of Flemoxin is accompanied by severe diarrhea, then the presence of pseudomembranous colitis can be assumed. In such cases, the drug must be discontinued.
