Mikardis Plus tablets: reviews, instructions for use, price, analogues

Reviews about Mikardin - a new nutraceutical with complex action for the cardiovascular system. It actively fights hypertension - high blood pressure, atherosclerosis, and also positions itself as a medicine for cleaning blood vessels from cholesterol plaques.

Old 1980 rub. on offer 990 rub.*

*when purchasing a course

The drug is new only because Micardin was actually launched under a new name. For the past three years, Micardis has been used exclusively by doctors in hospitals. Dispensed only as prescribed by doctors for the treatment of arterial hypertension, combating hypertensive crisis and cleaning blood vessels.

At the moment, Micardin capsules are sold in the public domain and are easy for anyone to buy. Therefore, hypertensive patients may not fear that the product has been poorly researched and not tested on real patients. And multiple positive reviews about reducing pressure and improving vascular patency will help you verify this.

When using Micardin, even in the most advanced cases, improvement was noted, which is why it received the approval of many specialists.

Micardis for hypertension has many advantages: organic composition, affordable price, convenient form of use in the form of capsules. But is it as effective as they say, or is it all just another scam to make money on naive citizens?

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Micardis Plus is a combination of telmisartan angiotensin type II receptor blocker hydrochlorothiazide ( diuretic ). The combined use of these components causes a stronger antihypertensive effect than using them separately. Taking the drug once a day leads to a pronounced gradual decrease in blood pressure.

Telmisartan is a selective angiotensin type 2 receptor blocker. Has high affinity for angiotensin II receptors of the AT1 subtype . It displaces angiotensin II from the receptor. The binding is long-term. Telmisartan does not block other receptors (including AT2 type receptors) of angiotensin . Telmisartan also reduces aldosterone .

In persons with arterial hypertension 80 mg of telmisartan per day completely suppresses the effects of angiotensin II . The onset of action occurs three hours after ingestion of the drug. The effect lasts for 24 hours. A permanent antihypertensive effect is observed a month after regular use of telmisartan .

Hydrochlorothiazide is diuretic . Affects the reabsorption of electrolytes in the renal tubules, directly increasing the excretion of sodium and chlorides. This causes a decrease in circulating blood volume, an increase in renin aldosterone synthesis .

After administration of hydrochlorothiazide, diuresis increases after two hours, and the maximum effect is achieved after four hours and persists for 6-12 hours.

Pharmacokinetics

Telmisartan. Quickly absorbed from the digestive tract. The maximum concentration of telmisartan occurs within an hour. Bioavailability is 50%.

Reaction with blood proteins is more than 99.5%. Metabolized by interaction with glucuronic acid . Telmisartan derivatives are pharmacologically inactive.

The half-life is approximately 20 hours. Excreted with feces in its original form and with the kidneys - up to 2%.

The pharmacokinetics of telmisartan in elderly patients does not differ from those in younger patients. No dose selection is required.

Hydrochlorothiazide. After oral administration of hydrochlorothiazide, maximum concentrations are achieved within 1-2 hours. Bioavailability reaches 60%.

Reaction with plasma proteins – 64%. It is not metabolized and is excreted unchanged through the kidneys.

Micardin, reviews from doctors about the dietary supplement for hypertension

The official resource contains reviews from two cardiologists. Khromova E.V. and Zelman D.G. According to them, Micardin allows you to achieve a sustainable reduction in systolic and diastolic pressure in a relatively short period of time, cleanses blood vessels of cholesterol and relieves vascular spasms.

Kolesnikov Viktor Pavlovich, cardiologist with 14 years of experience: “Recently, hypertension has become a common problem in cardiology. Traditional medications do not always help achieve long-term blood pressure reduction, and the cost is high. Therefore, as soon as I heard about the appearance of Micardin in the public domain, I decided to carefully study the medication.

I was pleased with the composition of the drug for hypertension. The advantage of organic products is that they do not have a negative effect on the gastrointestinal tract and rarely have contraindications.

Patients who had little help from synthetic drugs began to feel much better. Indicators and quality of life have improved. I definitely recommend Micardin for the treatment of cardiac patients."

Timofeeva Galina Andreevna, a therapist with 11 years of experience about Mikardis: “At the next advanced training course, a colleague advised us to introduce a new product for hypertension into the treatment practice - Micardin. I decided to listen to the opinion of an experienced doctor and took the capsules into account.

Against the background of hypertension, he developed atherosclerosis. No treatment method known to me helped the patient. The pressure has not stabilized at all. The drugs only relieved the symptoms for a short time, and the condition worsened.

At the appointment, the patient was prescribed a course of Micardin. I noticed improvements after 10 days. It was possible to clean the blood vessels, the pressure began to stabilize, and my health improved. Now he has almost no problems with blood pressure and is able to lead a full life.

I am grateful to my colleague for his good advice and will continue to use Micardin in my work.”

Doctors recommend Micardin due to the absence of contraindications, safe composition and clinically proven effect.

Contraindications

The drug has the following contraindications:

obstruction of the biliary tract;
severe liver or kidney dysfunction;
refractory hypercalcemia, hypokalemia ;
fructose intolerance ;
lactase deficiency galactose or lactose intolerance ;
age less than 18 years;
lactation;
pregnancy;
allergy to the components of the drug.

Carefully:

stenosis of both renal arteries, severe kidney damage;
liver dysfunction or progressive liver damage;
hyperkalemia;
hypovolemia after treatment with diuretics , as well as after limiting salt intake, vomiting or diarrhea ;
chronic heart failure , functional class III-IV;
mitral and aortic valve ;
condition after kidney transplant;
obstructive cardiomyopathy;
primary aldosteronism ;
diabetes;
gout.

Side effects

From the respiratory system: shortness of breath, respiratory distress syndrome .
From the circulatory system: tachycardia , arrhythmias , bradycardia , severe decrease in blood pressure.
From the nervous system: fainting, paresthesia , dizziness, insomnia , anxiety, depression , excitability, headache.
From the digestive system: flatulence, diarrhea, dry mouth, abdominal pain, constipation, gastritis, hypercholesterolemia, hyperglycemia, pancreatitis, jaundice, dyspepsia.
Skin: sweating.
From the musculoskeletal system: muscle spasms, arthralgia , myalgia , arthrosis , chest pain.
From the hematopoietic system: leukopenia, eosinophilia, anemia, neutropenia, thrombocytopenia, thrombocytopenia.
From the genitourinary system: renal failure, nephritis, glucosuria.
From the eyes: visual impairment, glaucoma, xanthopsia, acute myopia .
Infections: sepsis , respiratory tract infections ( pharyngitis, bronchitis, sinusitis ), inflammation of the salivary glands.
Metabolic disorders: increased creatinine, liver enzymes, creatine phosphokinase, uric acid in the blood, hypertriglyceridemia, hyperkalemia, hypokalemia, hypoglycemia, hyponatremia, decreased hemoglobin .
Allergic reactions : skin itching, angioedema , rash, erythema , anaphylactic reactions , eczema, systemic vasculitis, necrotizing vasculitis .

What is the reason for the negativity about the cleansing vessel?

Despite dozens of positive reviews about Micardin, there are still dissatisfied people who write negative reviews. In fact, it is stupid to blame the drug and call it useless for hypertension without first understanding the situations.

Often the negativity is associated with the fact that people buy the drug through wildberries, or through intermediaries. This immediately increases the risk of fraud. They may not deliver the goods to you at all, taking an advance payment, or they may sell you a counterfeit product. The original remedy for hypertension is sold only in the pharmacy of the official website.

Another reason is ignoring the instructions and dosage appropriate for age. A person drinks less, or, on the contrary, more, which is why the active substance does not reveal its potential correctly.

Some take Micardin only when their blood pressure rises. Others quit after a week. Capsules have a cumulative effect. To obtain the desired result, you should drink the full treatment course.

It is possible that other drugs were taken together with Micardin that neutralize the effect. Alcohol abuse also negatively affects results and causes consequences unrelated to the drug.

And, of course, it is worth remembering that any medicine can cause an allergic reaction. However, Micardin has an organic composition and will only cause a negative reaction if you are personally intolerant to the component.

To avoid such situations, those who suffer from certain allergies should read the ingredients before use to ensure they are safe for personal use.

Interaction

When using telmisartan with:

other antihypertensive drugs – it is possible to increase the strength of the antihypertensive effect ;
lithium preparations – a temporary increase in lithium in the blood is possible;
non-steroidal anti-inflammatory drugs acute renal failure may occur in patients with a reduced volume of circulating blood;
digoxin – it is possible to increase the concentration of digoxin in the blood by 20%.

When using hydrochlorothiazide with:

barbiturates, ethanol or opioid orthostatic hypotension may develop ;
Metformin – possible development of lactic acidosis ;
hypoglycemic agents and insulin - dose adjustment of hypoglycemic drugs ;
cholestyramine and colestipol - possible inhibition of hydrochlorothiazide ;
non-depolarizing muscle relaxants – their effect may be enhanced;
cardiac glycosides – possible development of hypokalemia or hypomagnesemia ;
anti-gout medications – it is possible to increase the level of uric acid in the blood.
calcium preparations – it is possible to increase the concentration of calcium in the blood due to inhibition of its excretion by the kidneys.
amantadine – there may be an increased risk of developing undesirable effects of amantadine ;
m-anticholinergic blockers ( atropine , biperiden ) – possible weakening of intestinal motility, increasing the bioavailability of thiazide diuretics ;
non-steroidal anti-inflammatory drugs - may weaken the diuretic and antihypertensive effects .

special instructions

In patients with coronary heart disease, the use of any blood pressure-lowering drug, in case of a strong decrease in pressure, can lead to the development of myocardial or cerebral infarction.

Micardis Plus has a weaker therapeutic effect in people of the Negroid race.

When driving vehicles, you should be aware of the possibility of dizziness and drowsiness after taking the drug.

Micardin real customer reviews

Of course, reviews from doctors with such extensive experience inspire confidence. However, before buying a complex, it is worth familiarizing yourself with the opinions of consumers and understanding whether it really helps with hypertension.

Lagutina Anna Gennadievna, 52: “I have been suffering from arterial hypertension and vascular stenosis for the past four years, I feel worst after a hard day at work and during a sudden change in weather. After all, cardiovascular disease is not uncommon in old age. I never parted with my blood pressure monitor, I even bought a second one for work. And due to the narrowing of blood vessels, capillaries constantly burst. I went to various doctors and underwent various rehabilitations. Neither paid nor free could help. They only said that obesity was to blame for poor health and advised to reduce the percentage of fat in the body. I tried a dozen antihypertensive drugs. All kinds of diuretics, drops and dietary supplements. Neither captopril, nor Corvalol, nor moxonidine, nor other drugs helped lower blood pressure. I completely despaired when my daughter came across Micardin. After carefully studying the information, I found a lot of good reviews about it and still decided to try it. We ordered and received it in the shortest possible time. I took one capsule twice a day. Soon I noticed results. It became much easier, there were no wild headaches. The pressure was still high, but gradually began to decrease. Now, after therapy, I use the tonometer only when I feel unwell, which is extremely rare. The deviation from the norm does not exceed 20 mmHg, when previously these values were the norm. I’m incredibly glad that I tried Micardis. If you also suffer from pressure surges and clogged blood vessels, purchase the drug and see for yourself that it really helps. I hope my review is helpful because these are excellent capsules for treating hypertension.

Denis My wife ordered Micardin for me because my blood pressure has started to rise lately. All you have to do is strain yourself or get a little nervous and you’ll immediately get 160/90. They diagnosed him with hypertension and prescribed medications. But you have to drink them constantly, and this affects the liver, kidneys, and stomach. I didn’t want to treat one thing and cripple the other. I went online to watch something easier. That’s how I found out about Micardin. Its composition is natural, which means it will not be so harmful. I took the full course, as was told to me over the phone. After this I have no problems with blood pressure. 120 by 80 like an astronaut. And I didn’t have to poison my body. And in terms of price, if you compare, a course of Micardin is more profitable than constantly spending money on pharmaceutical tablets that are of little use and harmful, too.

Kupriyanov Anatoly Vasilievich, 34: “My doctor prescribed Micardin to me because the tests did not improve any of the pills. Due to constant attacks of arrhythmia and tachycardia, I was very worried. I thought that one day I would have a heart attack, or an ischemic stroke due to exhaustion of the heart muscle. At such a young age it is very scary. Perhaps the pressure was affected by a sedentary lifestyle. I work as a programmer, I sit at the computer up to ten hours a day. I followed the doctor’s prescription immediately, and on the same day I bought Micardin from the pharmacy on the official website. At first, nothing changed, but the doctor warned that this was normal, since the blood and body were being cleansed. After two weeks, the number and severity of attacks decreased. The pulse returned to normal. It became easier to work, the shortness of breath stopped tormenting me. I began to devote more time to children, because active games in nature no longer caused my heart rate to increase. Doubts about effectiveness disappeared.

Marina To be honest, I’m still in slight shock from Micardin. I was sure that it was nonsense, just another bad thing, but my blood pressure really returned to normal, there have been no surges for 3 months! But I am an experienced hypertensive patient. The composition of the capsules is very good, there are components for the heart, blood vessels and immunity in general. If you drink it once every six months, I think you can maintain your health very well even at an advanced age. As for blood pressure, Micardin certainly doesn’t lower it right away. Only if you drink regularly, it prevents all these crises. The effectiveness is good, and not only I confirm this, I have 2 friends who also take it and are also satisfied. So I definitely recommend it. I just never write reviews, but here I was really impressed by this product in a good way.

Gurskaya Svetlana Konstantinovna ’24: “I have bad heredity with a heart on my mother’s side. Vegetative-vascular dystonia was diagnosed in childhood, but I lived calmly with this disease. However, after pregnancy the condition worsened. Constant dizziness, headaches, weakness, hyperemia of the skin. Previously, I took Beta blockers Bisoprolol and lisinopril, but they stopped helping. Then my friend, who also suffers from VSD, told me about Micardin. I read the instructions and asked to order one package. Before I started taking the capsules, I, of course, went to a consultation with a cardiologist and received the doctor’s approval. Now my life is back on track and the disease hardly causes any inconvenience. There were no adverse reactions, only positive dynamics. Extremely pleased with the effect of Micardis"

Anna Ryzhikova I met Micardin 3 months ago. While in line we started talking to the cardiologist, and one woman told me about him that it helps her well with her blood pressure. I read information about it on the Internet and decided to try it. I have hypertension, my heart hurts, and overall, at 55, I feel like I’m 70. I took the course and you know, I feel much better. My heart doesn’t ache, my blood pressure is excellent - 130 over 85. I’m slowly giving up other medications. I’ll take Micardin courses better, it’s natural and has no side effects.

Real reviews of Micardin from those who took it are favorable in 93% of cases. Buyers note that Micardin capsules are suitable for cleaning blood vessels and removing cholesterol plaques. The drug also fights hypertension and relieves high blood pressure.

The remaining 7% of customer reviews are negative. And the human factor plays a significant role here.

Analogues of Mikardis Plus

Level 4 ATX code matches:
Diokor

Gizaar

Teveten Plus

Atacand Plus

Co Diovan

Vazar N

Valz N

The following analogues of the drug are known: Atakand Plus , Valzap Plus , Valsacor , Gizaar Forte , Co-Diovan , Teveten Plus and others.

Price Mikardis Plus

In Ukraine, the price of the drug in a dosage of 80 mg/12.5 mg No. 28 averages 450 hryvnia; in Russia, such a package will cost 855-1000 rubles.

Online pharmacies in RussiaRussia
Online pharmacies in UkraineUkraine

ZdravCity

Mikardis Plus tablets 80 mg + 12.5 mg 28 pcs Boehringer Ingelheim
RUB 1,130 order

Pharmacy Dialogue

Mikardis plus (tab. 80 mg/12.5 mg No. 28)Boehringer Ingelheim
RUB 1,159 order
Mikardis plus tablets 80mg/12.5mg No. 28Boehringer Ingelheim
1111 rub. order

Negative reviews about Micardin for the treatment of hypertension

Zyryanova Valentina Georgievna, 56 years old: “Eleven months ago I was diagnosed with acute heart failure. Doctors prescribe expensive ACEIs (Angiotensin-converting enzyme inhibitors), which I, as a pensioner, cannot afford, and products from a cheaper price range do not help.

I read positive reviews and wanted to try Micardin. The price at the pharmacy turned out to be high, so I decided to look on the Internet. I found a website where they were asking half the price for the drug than on the official website, and bought it there.

In the end, the purchase was not delivered and the money was not returned. I am writing a review so that this does not happen to others. A scam for money, nothing more. I do not recommend purchasing Micardin.”

Answer: “Dear Valentina Georgievna, real Micardin is sold only on the official website, or in our pharmacy there. Third-party resources selling it at a lower price are scammers.”

Gribnikov Pavel Vasilievich 43: “After work I often suffer from high blood pressure. I don’t have time to go to the doctors, so I decided to look for a solution on my own. I came across the nutraceutical Micardin, read a bunch of reviews from doctors and customers about fighting hypertension and cleansing blood vessels, and ordered one package.

I took one tablet for a week when I didn’t feel well. The medication did not relieve high blood pressure, the problem remained. The laudatory reviews are complete nonsense. I threw money away."

Answer: “Dear Pavel Vasilyevich, Micardin is used strictly according to the instructions, or in dosages prescribed by the doctor. But the result may not appear in the first days, this is indicated in the instructions.”