Claritin is one of the most popular anti-allergy medications. He belongs to the third generation. This means that its antihistamine activity is higher, it practically does not cause drowsiness (only if the dosage and administration regimen is violated), and does not interact with other medications.
The main active ingredient of this drug is loratadine. The medicine is available in the form of tablets and syrup. Claritin acts quite quickly and for a long time. So, it enters the active phase after 30 minutes, and the maximum antihistamine effect appears after 8-12 hours and lasts for at least 24 hours.
The drug eliminates itching of the nasal mucosa, sneezing, runny nose and nasal congestion. Also, the drug removes the sensation of burning and itching in the eyes, lacrimation.
Features of the drug
The active ingredient in Claritin is loratodine. The antiallergic drug is produced in two forms:
- In the form of tablets. They are distinguished by their white color and round shape. One side of them is absolutely smooth, and on the other there is a trademark “Cup and Flask” sign. The dosage of the active substance is also indicated as 10 mg.
- In the form of syrup. The solution may be colorless or have a yellow tint. 1 ml of syrup contains 1 mg of loratodine. The product is packaged in dark glass bottles of 60 and 120 ml.
This drug belongs to the group of third generation antihistamines. It is highly active. But at the same time, the drug does not provoke lethargy and drowsiness after taking it.
The peculiarity of the antiallergic drug is to obtain a quick result and maintain a long-lasting effect. Half an hour after administration, a significant improvement in the condition is observed. The maximum effect is achieved after approximately 8-12 hours and lasts throughout the day.
Claritin for children
Young patients can be treated with the drug in the form of tablets or syrup. In this case, children can take the medicine once a day in a certain dosage.
The instructions for Claritin for children recommend calculating the dosage depending on weight. For example, with a weight of up to 30 kg, it is permissible to take syrup for children daily, 1 teaspoon or ½ tablet.
Patients weighing more than 30 kg are prescribed 2 teaspoons of syrup or 1 tablet daily. As a rule, parents leave positive reviews about syrup for children online.
Indications
Claritin, the instructions for use confirm this, is prescribed to relieve unpleasant allergic reactions. In particular, these are lacrimation, runny nose, sneezing, etc.
The main indications include the following pathological conditions:
- Allergic rhinitis or conjunctivitis, which can occur year-round.
- Hay fever, which is a seasonal disease and occurs as a reaction to plant pollen.
- Chronic urticaria, which is provoked by various substances due to individual intolerance.
- Allergic reactions on the skin, provoked by various external and internal factors.
Claritin price, where to buy
The price of Claritin tablets is 130-570 rubles.
The price of Claritin syrup varies between 220-380 rubles.
The price of Claritin in Ukraine (in cities such as Kyiv and Kharkov) ranges from 156 UAH.
You can buy the drug in St. Petersburg for a price starting from 140 rubles. At the same time, the cost in Russian regions is somewhat lower. You can find out how much medicine for allergies of any form costs at a reference pharmacy in the city you are interested in or on pharmacy websites.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Claritin tab.
0.01g 10pcs Bayer Bitterfeld GmbH RUB 142 order - Claritin tab. 0.01g 30pcs Bayer Bitterfeld GmbH
400 rub. order
Pharmacy Dialogue
- Claritin tablets 10 mg No. 30Shering-Plough Labo
RUB 376 order
- Claritin (tab. 10 mg No. 10) Bayer Bitterfeld GmbH
RUB 149 order
- Claritin (tab. 10 mg No. 30) Bayer Bitterfeld GmbH
RUB 377 order
- Claritin tablets 10 mg No. 10Shering-Plough Labo
135 rub. order
- Claritin tablets 10 mg No. 30Shering-Plough
RUB 394 order
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Pharmacy24
- Claritin syrup 60 ml Schering-Plough Labo N.V., Belgium
94 UAH.order - Claritin 10 mg No. 10 tablets Schering-Plough Labo N.V., Belgium
91 UAH order
PaniPharmacy
- Claritin tablets Claritin tablets 10 mg No. 10 Belgium, Schering-Plough Labo
97 UAH order
- Claritin liquid Claritin syrup 60ml Belgium, Schering-Plough Labo
95 UAH order
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Contraindications and negative reactions of the body
An absolute contraindication to the use of Claritin tablets and syrup is individual intolerance to the active substance. In addition, the drug is not prescribed until the age of 2 years. The drug is contraindicated during lactation, as if it passes into breast milk it can harm a newborn baby.
With extreme caution and only after consulting a doctor, you should use a remedy to relieve allergic reactions during pregnancy and if renal failure is confirmed.
If the dosage is observed and contraindications are excluded, claretin, the instructions for use indicate this, rarely causes negative reactions in the body. In adult patients, the following side effects were observed after taking the drug:
- Headache.
- Drowsiness
- Increased fatigue.
- Gastrointestinal disorders.
Occasionally, unpleasant dry mouth is noted while taking the product, according to reviews. At the same time, the instructions for use of the antihistamine do not exclude more serious side effects: tachycardia, alopecia, liver problems, etc.
When using syrup in children, among the negative reactions, most often there is a pronounced sedative effect. Sometimes headaches occur, increased excitability and nervousness are observed.
An overdose of the drug causes headache, drowsiness, and tachycardia. If it is confirmed, then you need to rinse your stomach and take absorbents. After this, you should consult a doctor. In severe cases, it is not always possible to stabilize the condition with symptomatic therapy. In case of overdose, control over the patient's condition is required.
Instructions for use
Claritin is available in two dosage forms - tablets and syrup. Each of them can be taken orally at any time of the day, regardless of food. The tablets can be taken by adult patients and children over 12 years of age. The syrup is intended for children over 2 years of age and patients who, for one reason or another, cannot take tablets.
Recommended dosage and regimen:
Claritin for adults and children over 12 years of age: 1 tablet (10 mg) or 2 teaspoons of syrup (10 ml) 1 time per day. If the patient’s history contains a note of impaired liver function or renal failure, then the following dosage and regimen is prescribed: 1 tablet (10 mg) or 2 teaspoons of syrup (10 ml) every other day.
For children aged 2 to 12 years, the dose is calculated depending on body weight:
For body weight less than 30 kg: 1 teaspoon (5 ml) syrup or 1/2 tablet (5 mg) 1 time per day.
For body weight 30 kg or more: 2 teaspoons (10 ml) of syrup or 1 tablet (10 mg) 1 time per day.
In cases of overdose, tachycardia, drowsiness and/or headaches may occur. If such a development occurs, you should consult a doctor. If an overdose is established, then therapy includes: gastric lavage, then taking adsorbents and symptomatic medications.
During pregnancy and lactation
The drug can only be prescribed to pregnant women by a doctor.
The drug Claritin can only be prescribed to a pregnant woman by a doctor. Moreover, the instructions for use indicate that it should be used with caution and only in cases where the expected benefit of therapeutic treatment for the mother is higher than the risk for the unborn baby.
Regarding the period of breastfeeding. This is a direct contraindication to the use of Claritin, since clinical studies have shown the penetration of the active substance into breast milk.
Claritin for children
Treatment of allergies in children is carried out only with the permission of the pediatrician and allergist. You can use any convenient form - syrup or tablets. But it is worth remembering that it is difficult for small children to swallow tablets, so it is preferable to use a different dosage form.
The drug can only be taken with the permission of a pediatrician or allergist.
The dosage for young patients who have not reached 12 years of age is calculated based on the patient’s weight. More information about dosages and dosage regimen can be found in the Claritin section, instructions for use.
Interaction with other drugs
Judging by clinical studies, Claritin combines well with other medications. Thus, when taking Ketoconazole, Erythromycin or Cimetidine simultaneously, the concentration of loratadine in the body may increase, but no special manifestations will follow.
Claritin and alcohol
You should not abuse the compatibility of alcohol and Claritin
Can I take alcohol and Claritin at the same time? This antihistamine belongs to the modern, latest third generation. The instructions for use indicate that it does not have a negative effect on the central nervous system, brain function, or the speed of psychomotor reactions. It is believed that a combination of the drug and alcohol is possible, but it should not be abused. Alcohol does not have any special effect on the effectiveness of the drug, but it may increase the likelihood of side effects such as drowsiness, severe headache, dizziness, tachycardia, and increased blood pressure. For this reason, it is recommended to refrain from taking Claritin and alcoholic beverages at the same time. If the patient is undergoing a course of drug therapy, then you should not drink alcohol to avoid complications.
Application
You can take claretin, which is affordable, at any time of the day, regardless of meals. The following should be taken into account:
- Tablets are allowed to be used only after reaching the age of 12 years.
- The syrup is approved for use from the age of two. It is also prescribed in cases where, for any reason, problems arise with the use of tablets.
- The dosage of syrup for children is calculated individually based on weight.
Detailed recommendations are contained in the instructions for use of the drug. They should be followed unless otherwise prescribed by the doctor. For ease of use of the syrup for children, the bottle comes with a measuring spoon or a 5 ml graduated syringe.
Reviews of Claritin
There are quite often reviews on the Internet about Claritin tablets and syrup, but users’ opinions about its effect are very ambiguous. Many people report that treatment with this drug has been effective for them. Although some patients had to look for a more suitable remedy, since their allergic symptoms decreased only slightly.
As allergists—specialists who study and treat this disorder—specify, every person can be bothered by allergies of various kinds. Therefore, one drug is simply not able to eliminate the manifestation of various symptoms. For these patients, the only option is to take several different medications or forms of them, such as tablets and nasal spray.
Despite their high popularity, both tablets and syrup for children do not have such a wide spectrum of action that allows them to simultaneously eliminate all manifestations of allergies. Moreover, there are also reports of the development of side effects, for example, headache, drowsiness, and skin manifestations. Of course, if any unwanted reactions occur, you should consult a doctor to rule out the presence of another disease with similar symptoms.
The fact that this drug is sold in pharmacies without a prescription does not mean that you can take it yourself without a prescription from an allergist. Therefore, if symptoms appear that indicate the development of an allergy, you should immediately consult a doctor. If this is not done in a timely manner, the symptoms will gradually worsen.
Special Recommendations
If skin testing is required, you should stop taking Claritin three days before the test. Otherwise, the antihistamine will distort the test results.
The effectiveness of the product does not depend on food intake. Also, with the use of an antiallergic drug, there is no deterioration in psychomotor reactions. Therefore, there are no restrictions on performing precise operations with complex mechanisms or driving vehicles. It should be borne in mind that one of the side effects when taking the drug is drowsiness, which can affect reactions.
Since the antihistamine drug Claritin belongs to the third generation, it does not have a negative effect on the central nervous system. This means that the combination of alcohol with it is allowed, but it is not recommended to abuse it. Since while maintaining the effectiveness of the active substance, there is a risk of increased negative reactions of the body and any complications.
The shelf life of Claritin is 3 years. Taking expired medication is strictly prohibited. For storage you need to find a place where children do not have access. You can purchase the third generation antihistamine drug claretin in pharmacies without a prescription.
Analogues of Claritin
When prescribing this antihistamine, a reasonable question arises as to what can replace it. Most often, inexpensive drugs containing the same active substance or drugs belonging to the same generation are offered as analogues. Analogues of Claritin are very popular: Loratadine, Lomilan, Claridol and Clarotadine. Also have a similar effect: Erius, Lotharen, Clallergin, Clarisens, Clarifarm, Clarifer, Clarfast, Loragexal, Alerpriv, Clargotil and Erolin.
Analogs
Claritin or Erius?
Both drugs are new generation antihistamines. Therefore, effectiveness and a minimum of side effects are inherent in each of these drugs. But it is believed that Erius has a wider spectrum of action.
Claritin or Loratadine?
The drugs contain the same active ingredient, but they still have differences.
Loratadine is a highly effective antiallergic drug of the second generation, but Claritin is already in the third generation. The therapeutic effect of taking it occurs faster, and the effect can last more than 24 hours. And he is also less likely to experience adverse reactions.
Claritin or Suprastin?
If Suprastin is compared with Claritin, then both antihistamines help well with allergies and have the same indications for use. They act quickly and effectively. Despite similar characteristics, the drugs differ. First of all, composition and generation. These medications have different active ingredients. Suprastin has chloropyramine, and Claritin has loratadine. Suprastin is a first generation antihistamine, and Claritin is a third generation. This means that Suprastin is not as selective in terms of blocking receptors and causes drowsiness. Claritin does not affect the central nervous system and provokes a sedative effect. But Suprastin can be used for infants, starting from the first month of life. Claritin is only allowed for children over two years of age. When taking the latter, the risk of adverse reactions is negligible. In addition, the use of Suprastin is undesirable if you are prone to bronchospasms, since sputum discharge is difficult.
Claritin has a prolonged effect, and one tablet per day is enough, in contrast to 2-3 doses of Suprastin.
It is believed that Claritin is stronger and better, but in some cases only Suprastin can help. For example, during acute attacks Suprastin in ampoules is preferable. Moreover, one of the indications for use is angioedema and anaphylactic reactions. In such conditions, Claritin will not help. Suprastin is effective for serum sickness and fever after vaccinations. It turns out that the drug in question acts more gently and is able to relieve mild and moderate allergic reactions.
Claritin tablets 10 mg No. 10
A country
Belgium
Country of manufacture may vary depending on the batch of goods. Please check with the operator for detailed information when confirming your order.
Active substance
Loratadine
a brief description of
The drug Claritin is included in the category of antihistamine drugs and acts for about 24 hours, there is no drowsiness. As a brief description, it should be noted that the active substance of Claritin is Loratadine. Produced by pharmaceutical companies in Belgium under the brand name Schering-Plough Labo. Prescribed to reduce the intensity of allergic reactions of various natures. ATX code – R06 AX13. During the flowering seasons of plants, many people experience aggravation of various manifestations of allergies, for example, runny nose, headaches, sneezing, skin rashes, and difficulty breathing. There are many antihistamine drugs that can eliminate these symptoms, but at the same time they reduce performance, cause drowsiness, their duration of action is limited to a few hours, and there are a lot of side effects. In this case, you should pay attention to Claritin, which relieves the symptoms of allergic reactions and also acts throughout the day without any negative effects on the general well-being of a person. But before choosing this particular drug, you need to read the instructions for using Claritin in order to identify possible contraindications and study the rules for taking the medication.
Doses
Permissible doses of Claritin vary depending on the age category of the patient and the pharmacological form of the drug. For a positive effect, adults only need to take one tablet (10 mg) per day. Children under 12 years of age should calculate the dosage based on body weight. So, if the child’s weight is less than 30 kilograms, then it is recommended to replace the tablets with syrup. If you weigh more than 30 kilograms, the dosage is the same as for adults – 1 tablet. during the day. For patients in the older age group, no dosage adjustment is required. But if you have functional liver pathologies, you need to take Claritin in minimal doses. For children, the permissible dose of the medication is 10 milligrams per day. For children under three years of age, allergy treatment with Claritin is contraindicated.
Release forms Claritin
For ease of administration, Claritin is produced in several forms: • water-based syrup; • pills. The tablet form is packaged in plates of 7 tablets, 10 tablets, 15 tablets. The package can contain 1-3 plates. The syrup is available in glass bottles with a total volume of 60-120 milliliters. The kit includes a graduated syringe or a plastic measuring spoon for ease of taking the drug.
Analogues of Claritin
Pharmacological analogues of Claritin are drugs with the same active substance or drugs with a similar effect: • Alefin; • Loratadine; • Clargotil; • Agistam; • Lorizan; • Erolin; • Lorfast; • Pulmolor; • Loridin Rapid; • Eveik-Md; • Laurent ODT; • Loratadine-CR and others.
How to take Claritin?
In order for the drug to have a more effective therapeutic effect, it is enough to take it once a day. If the patient’s history shows signs of impaired functional properties of the liver, then it is recommended to take Claritin every other day, that is, after 24 hours. It is better not to use an antihistamine during pregnancy. The exception is when the health of the mother is a priority over the risk to the fetus. You should refrain from eliminating allergies with Claritin while breastfeeding. One of the main contraindications to the use of Claritin is individual intolerance to Loratadine and other substances that are part of the chemical composition of the drug.
Action of Claritin
The main effect of Claritin is to reduce the intensity and eliminate allergy symptoms. The patient notices the first signs of improvement half an hour after taking the tablet or syrup. Maximum effectiveness is achieved within 9-11 hours and the effect lasts about a day. In case of severe allergic reactions, patients can take a double dose of Claritin, but this, instead of the desired relief of the condition, can lead to a drug overdose. An overdose is manifested by symptoms such as headaches, drowsiness, rapid pulse (tachycardia). The first aid in this situation is gastric lavage, taking the required amount of activated carbon to absorb the drug (dosage - 1 tablet per 10 kilograms of the patient’s weight). An overdose can develop not only as a result of exceeding the dosage of Claritin, but also when taking various antihistamines together. Therefore, you can combine medicinal substances only after consultation with your doctor.
Is it compatible with alcohol?
Combining medications with alcoholic beverages has never benefited anyone. Claritin is no exception. During studies, the effect of the drug on the nervous system was not noted, but some inhibition is possible. And additional exposure to alcohol can lead to significant depression of the central nervous system. Also, the dose of Claritin for liver disease should be reduced. Alcohol-containing drinks have a destructive effect on the liver. The combination of these two factors can provoke a decrease in the functional properties of the liver. In this regard, the simultaneous use of alcohol and Claritin is unacceptable.
Does Claritin make you drowsy?
Loratadine, which is part of the chemical composition of Claritin, has little effect on the central nervous system. After taking the medicine, the patient does not feel additional drowsiness. If drowsiness is associated specifically with the use of Claritin, then this is considered a side effect, which can be eliminated by replacing the drug with one of its analogues.
Claritin side effects
Treatment with Claritin sometimes causes side effects. For example, nausea, vomiting, inflammation of the gastric mucosa, headaches, dry mouth, fatigue, nervous conditions, and drowsiness may appear. Rarely, but still, cases of alopecia - hair loss - have been reported. What diseases does Claritin help with? The antiallergic drug Claritin is prescribed to eliminate the clinical manifestations of allergies: • rhinoconjunctivitis; • itching in the nasal passages; • burning of the conjunctiva of the eyes; • sneezing; • lacrimation. The drug is also used for skin lesions, for example, allergic urticaria.
Pharmacological properties
Patients who cope with seasonal exacerbations of allergies did not report any anticholinergic or strong sedative effects. With long-term treatment, no clinical changes in the functioning of internal organs and systems were observed. In addition, the drug does not exert additional stress on the cardiovascular system. Laboratory studies of skin tests after taking 10 milligrams of Claritin showed that the antiallergic effect is achieved after approximately 2 hours, and peak effectiveness occurs within 12 hours. The drug is not addictive even after a month of regular use.
Who is Claritin tablets suitable for?
Anyone prone to seasonal allergy flare-ups is trying to find the perfect way to relieve symptoms with minimal impact on daily life. When the nose does not breathe, the head is cast iron and the whole body itches, the patient is looking for any remedy that will help alleviate this condition. It is in this case that many people choose Claritin. The allergy does not go away in 1-2 days, so the chosen drug should not have side effects in the form of decreased concentration and performance, or drowsiness. Doctors do not advise car drivers to take many antihistamines. Unlike them, Claritin does not affect the nervous system and maintains clarity of thought and good spirits throughout the working day.
Results
Claritin is one of the safest medications with antihistamine properties. The medicine can be bought at your nearest pharmacy without a doctor's prescription. The shelf life of the tablet form of Claritin is about 4 years, liquid syrup can be used for 3 years from the date of manufacture. This means that the drug can be carried with you at temperatures up to 25 degrees and used at the first manifestation of an allergy.
Compound
1 tablet contains the active substance: loratadine 10 mg; excipients: lactose monohydrate 71.3 mg, corn starch 18 mg, magnesium stearate 0.7 mg. Description Oval-shaped tablets, white or almost white, free of foreign inclusions, on one side there is a line mark, the trademark “Cup and Flask” and the number “10”, the other side is smooth. Release form Tablets 10 mg. 7, 10 or 15 tablets in blisters made of polyvinyl chloride and aluminum foil. 1, 2 or 3 blisters along with instructions for use in a cardboard box.
Pharmacological properties
Pharmacodynamics Loratadine, the active substance of the drug Claritin®, is a tricyclic compound with a pronounced antihistamine effect and is a selective blocker of peripheral H1-histamine receptors. Has a quick and long-lasting antiallergic effect. The onset of action is within 30 minutes after taking the drug Claritin® orally. The antihistamine effect reaches its maximum after 8-12 hours from the onset of action and lasts more than 24 hours. Loratadine does not penetrate the blood-brain barrier and has no effect on the central nervous system. Does not have a clinically significant anticholinergic or sedative effect, i.e. does not cause drowsiness and does not affect the speed of psychomotor reactions when used in recommended doses. Taking the drug Claritin® does not lead to prolongation of the QT interval on the ECG. During long-term treatment, no clinically significant changes in vital signs, physical examination findings, laboratory results, or electrocardiography were observed. Loratadine does not have significant selectivity for histamine H2 receptors. Does not inhibit norepinephrine reuptake and has virtually no effect on the cardiovascular system or pacemaker function. Pharmacokinetics Loratadine is rapidly and well absorbed from the gastrointestinal tract. The time to reach the maximum concentration (Tmax) of loratadine in the blood plasma is 1-1.5 hours, and its active metabolite desloratadine is 1.5-3.7 hours. Eating food increases the time to reach maximum concentration (Tmax) of loratadine and desloratadine by approximately 1 hour, but does not affect the effectiveness of the drug. The maximum concentration (Cmax) of loratadine and desloratadine is independent of food intake. In patients with chronic kidney disease, the maximum concentration (Cmax) and area under the concentration-time curve (AUC) of loratadine and its active metabolite are increased compared to patients with normal renal function. The half-lives of loratadine and its active metabolite do not differ from those in healthy patients. In patients with alcoholic liver damage, the Cmax and AUC of loratadine are doubled compared to these values in patients with normal liver function, while the pharmacokinetics of its active metabolite does not change significantly. Loratadine has a high degree (97-99%), and its active metabolite has a moderate degree (73-76%) of binding to plasma proteins. Loratadine is metabolized to desloratadine via the cytochrome P450 3A4 system and, to a lesser extent, the cytochrome P450 2D6 system. Excreted through the kidneys (approximately 40% of the oral dose) and intestines (approximately 42% of the oral dose) for more than 10 days, mainly in the form of conjugated metabolites. Approximately 27% of an oral dose is excreted through the kidneys within 24 hours of taking the drug. Less than 1% of the active substance is excreted unchanged through the kidneys within 24 hours after taking the drug. The bioavailability of loratadine and its active metabolite is dose-dependent. The pharmacokinetic profiles of loratadine and its active metabolite were comparable in adults and elderly healthy volunteers. The half-life of loratadine ranges from 3 to 20 hours (average 8.4 hours), and that of desloratadine ranges from 8.8 to 92 hours (average 28 hours); in elderly patients, respectively, from 6.7 to 37 hours (average 18.2 hours) and from 11 to 39 hours (average 17.5 hours). The half-life increases with alcoholic liver damage (depending on the severity of the disease) and does not change in the presence of chronic renal failure. Hemodialysis in patients with chronic renal failure does not affect the pharmacokinetics of loratadine and its active metabolite.
Indications for use
Seasonal (hay fever) and year-round allergic rhinitis and allergic conjunctivitis - elimination of symptoms associated with these diseases - sneezing, itching of the nasal mucosa, rhinorrhea, burning and itching sensation in the eyes, lacrimation. Chronic idiopathic urticaria.
Contraindications
Intolerance or hypersensitivity to loratadine or any other component of the drug. Children under 3 years of age and body weight less than 30 kg. Breastfeeding period. Patients with rare hereditary diseases (impaired galactose tolerance, Lapp lactase deficiency or glucose-galactose malabsorption). With caution: Severe liver dysfunction. Pregnancy (see section “Use during pregnancy and breastfeeding”). Use during pregnancy and breastfeeding A large amount of data on the use of loratadine in pregnant women (more than 1000 analyzed cases) indicates that the drug does not influence the occurrence of malformations or feto- and neonatal toxicity of loratadine. No reproductive toxicity was observed in animal studies. As a precaution, it is advisable to avoid using the drug during pregnancy. Loratadine and its active metabolite are released in breasts. If the drug is prescribed during breastfeeding, the issue of stopping breastfeeding should be decided.
Mode of application
Inside, regardless of meal time. Adults, including the elderly, and adolescents over 12 years of age are recommended to take Claritin® at a dose of 10 mg (1 tablet) once a day. When using the drug in elderly patients and in patients with chronic renal failure, no dose adjustment is required. Children aged 3 to 12 years weighing more than 30 kg - 10 mg (1 tablet) 1 time per day. For adults and children weighing more than 30 kg with severe liver dysfunction, the initial dose should be 10 mg (1 tablet) every other day.
Side effect
In clinical studies involving children aged 2 to 12 years, headache (2.7%), nervousness (2.3%), fatigue were observed more often than in the placebo group (dummies). (1 %). In clinical studies in adults, adverse events observed more often than with placebo occurred in 2% of patients taking Claritin®. In adults, when using the drug Claritin®, headache (0.6%), drowsiness (1.2%), increased appetite (0.5%) and insomnia (0.1%) were observed more often than in the placebo group. According to the World Health Organization (WHO), side effects are classified according to their frequency as follows: very often (≥ 1/10), often (≥ 1/100 to Information on side effects is provided based on the results of post-registration observations. From the side immune system: very rarely - allergic reactions (including angioedema, anaphylaxis). From the nervous system: very rarely - dizziness, convulsions. From the cardiovascular system: very rarely - tachycardia, palpitations. From the digestive system: very rarely - dry mouth, nausea, gastritis. From the liver and biliary tract: very rarely - impaired liver function. From the skin and subcutaneous tissues: very rarely - rash, alopecia. General disorders: very rarely - fatigue. Laboratory and instrumental data: frequency unknown - weight gain If any of these side effects get worse or you notice any other side effects not listed in the instructions, tell your doctor.
Overdose
Symptoms: drowsiness, tachycardia, headache. In case of overdose, consult a doctor immediately. Treatment: symptomatic and supportive therapy. It is possible to lavage the stomach and take adsorbents (crushed activated carbon with water). Loratadine is not eliminated by hemodialysis. After emergency care is provided, it is necessary to continue monitoring the patient's condition.
Interaction
Eating does not affect the effectiveness of Claritin®. The drug Claritin® does not enhance the effects of alcohol on the central nervous system. Potential interactions may occur with all known inhibitors of CYP3A4 or CYP2D6, resulting in increased plasma levels of loratadine and an increased risk of side effects. When loratadine was co-administered with ketoconazole and erythromycin (inhibitors of the CYP3A4 isoenzyme) or cimetidine (inhibitor of the CYP3A4 and CYP2D6 isoenzymes), an increase in the concentration of loratadine in plasma was observed, but this increase was not clinically significant, including according to electrocardiography. When used simultaneously with drugs that inhibit hepatic metabolism, caution should be exercised.
special instructions
Taking Claritin® should be stopped 48 hours before skin testing, as antihistamines may interfere with diagnostic test results. Effect on the ability to drive vehicles and operate machinery. No negative effect of the drug Claritin® on the ability to drive a car or perform other activities that require increased concentration has been identified. However, in very rare cases, some patients experience drowsiness while taking Claritin®, which may affect their ability to drive or operate machines.
