pharmachologic effect
Due to the combined composition, the drug has antimicrobial, antibacterial and dehydrating properties.
It has therapeutic activity against gram-negative and gram-positive bacteria. The active ingredient, chloramphenicol, does not violate the integrity of cell membranes, easily penetrates deep into tissues, promotes their regeneration and removal of purulent contents. In addition, when using the ointment, there is a decrease in swelling, inflammation and strengthening of the body's defenses at the local level.
Levomicon-TFF
Dosage form:
Ointment for external use
Ingredients: active ingredients
: Dioxomethyltetrahydropyrimidine (methyluracil) – 4.0 g, chloramphenicol – 0.75 mg;
Excipients
: macrogol 1500 – 19.05 mg, macrogol 400 – 76.2 g.
Description
The ointment is white or white with a yellowish tint.
Pharmacotherapeutic group
Combined antimicrobial agent.
ATX code: D06С
Pharmacological properties
A combined preparation for external use that has anti-inflammatory (dehydrating) and antimicrobial effects. Chloramphenicol disrupts the process of protein synthesis in the microbial cell and is a bacteriostatic antibiotic.
Active against gram-positive and gram-negative microorganisms (staphylococci, Pseudomonas aeruginosa and Escherichia coli, etc.). Easily penetrates deep into tissues without damaging biological membranes. In the presence of pus and necrotic masses, the antibacterial effect remains. Dioxomethyltetrahydropyrimidine, normalizing nucleic acid metabolism, stimulates regeneration processes in wounds, growth and granulation maturation of tissue, epithelization, and has an anti-inflammatory (dehydrating) effect.
Indications for use
Purulent wounds (including those infected with mixed microflora) in the first (purulent-necrotic) phase of the wound process. If necessary, please consult your doctor before using the medicine.
Contraindications
Hypersensitivity to the components of the drug, children under one year of age (in newborns, the biotransformation of chloramphenicol occurs more slowly than in adults).
Carefully
Pregnancy, lactation period.
Use during pregnancy and breastfeeding
Use during pregnancy is possible only if the benefit to the mother outweighs the risk to the fetus.
During lactation, you should either stop using the drug or breastfeeding.
Directions for use and doses
Externally. The drug is impregnated with sterile gauze pads, which are used to loosely clean the wound. It is possible to administer the drug into purulent cavities through a catheter (drainage tube) using a syringe. In this case, the ointment is preheated to 35-36 °C. Dressings are performed daily, once a day, until the wound is completely cleansed of purulent-necrotic masses. For large wound surfaces, the daily dose of ointment in terms of chloramphenicol should not exceed 3 g. The duration of treatment depends on the severity and course of the disease. If there is no improvement after treatment or new symptoms appear, you should consult your doctor. Use the drug only according to the method of use and in the doses indicated in the instructions. If necessary, please consult your doctor before using the medicine.
Side effect
Allergic reactions (skin rashes). In this case, you should stop using the drug and consult a doctor. If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.
Overdose
No cases of overdose have been reported.
Drug interactions
Cases of interaction or incompatibility with other drugs have not been described.
special instructions
When applied to large areas of skin and long-term courses of treatment, it is necessary to conduct a clinical blood test.
Impact on the ability to drive vehicles and machinery
Does not affect the ability to drive vehicles and other mechanisms.
Release form
Ointment for external use.
20, 25, 30, 40, 50, 60, 70, 80, 100 g in orange glass jars with a triangular rim with a pull-on lid with a sealing element.
20, 25, 30, 40, 50, 60, 70, 80, 100 g in polymer jars complete with lids and polyethylene terephthalate jars with closures.
20, 25, 30, 40, 50, 60, 70, 80, 100 g in aluminum tubes, coated with BF-2 varnish, with caps made of high-density polyethylene or in polymer tubes with polyethylene screw caps.
Each jar and tube, along with instructions for use, is placed in a cardboard pack.
Storage conditions
At a temperature not exceeding 20 °C.
Keep out of the reach of children.
Best before date
3 years 6 months. Do not use after the expiration date stated on the label.
Vacation conditions
Available without a prescription.
What is Levomekol used for?
The drug is prescribed for the treatment of the following conditions:
- Skin infections due to pathogenic pathogens.
- Calluses.
- Pimples, boils, blackheads.
- Burn lesions, especially 2nd and 3rd degrees.
- Inflammation of the ear and sinuses with purulent discharge.
- Hemorrhoids.
- Bedsores.
- Postoperative wound care.
- Death of individual sections of tissue.
- Eczema.
How to use Levomekol correctly
Levomikol in the form of leniment is used topically for adults and children over 3 years of age. Depending on the indication, there are some differences in use.
In addition to applying the ointment to the affected areas, it can be administered through a syringe to wash out purulent cavities. To do this, the medicine is heated to 36 C.
When treating various infectious skin diseases, it is worth adhering to the therapeutic dose. The amount of ointment per day should not exceed 3 g. The course duration is 4 days. It is prohibited to use the product for longer to avoid an osmotic state in the affected cells.
Levomethyl ointment for external use 30g
Compound
Per 100 g:
Active ingredients
: chloramphenicol (chloramphenicol) - 0.75 g, dioxomethyltetrahydropyrimidine (methyluracil) - 4.0 g,
Excipients
: macrogol 400 (polyethylene oxide 400) - 76.2 g, macrogol 1500 (polyethylene oxide 1500) - 19.05 g.
Pharmacokinetics
The drug is absorbed slightly and does not have a systemic effect.
Indications for use
Purulent wounds (including those infected with mixed microflora) in the first (purulent-necrotic) phase of the wound process.
Contraindications
Unlikely due to low absorption. When applying the ointment to large surfaces and long-term treatment, symptoms of the hematopoietic system may appear - anemia, leukopenia, thrombocytopenia, reticulocytopenia, which usually disappear after stopping the drug and prescribing symptomatic therapy.
Directions for use and doses
Externally. A strip of ointment with a diameter of 5 mm and a length of 1 cm has an average mass of 0.3 g, which corresponds to 10 mg of chloramphenicol and 20 mg of dioxomethyltetrahydropyrimidine. For adults and children, the drug is applied once a day directly to damaged areas of the skin at the rate of 0.3 g per 1 cm2 of the wound surface or applied to sterile gauze napkins at the rate of 0.3-0.6 g per 1 cm2 of the wound surface, cover the damaged area with a napkin area of skin and secure with a bandage. Deep wounds are loosely filled with sterile gauze pads soaked in the drug. The drug is injected into the purulent cavities with a syringe through a catheter or drainage tube, after preheating the ointment to 35-36 C. Dressings are carried out daily, once a day, until the wound is completely cleansed of purulent-necrotic masses. The daily dose of ointment in terms of chloramphenicol should not exceed 3 g of chloramphenicol.
The course of treatment is from 5 to 14 days, depending on the severity and course of the disease.
Storage conditions
In a dry place, protected from light, at a temperature of 12 - 15 C.
Keep out of the reach of children.
Best before date
3 years 6 months. Do not use after expiration date.
special instructions
When applied to large areas of skin and long-term courses of treatment, it is necessary to conduct a clinical blood test.
Description
The ointment is white or white with a yellowish tint.
Conditions for dispensing from pharmacies
For hospitals
Dosage form
ointment for external use
Manufacturer and organization accepting consumer complaints
JSC "Green Dubrava"
Pharmacodynamics
A combined preparation for external use that has anti-inflammatory (dehydrating) and antimicrobial effects. Chloramphenicol disrupts the process of protein synthesis in the microbial cell and is a bacteriostatic antibiotic. Active against gram-positive and gram-negative microorganisms (staphylococci, Pseudomonas aeruginosa and Escherichia coli, etc.). Easily penetrates deep into tissues without damaging biological membranes. In the presence of pus and necrotic masses, the antibacterial effect remains. Dioxomethyltetrahydropyrimidine, normalizing nucleic acid metabolism, stimulates regeneration processes in wounds, growth and granulation maturation of tissue, epithelization, and has an anti-inflammatory (dehydrating) effect.
Side effects
Allergic reactions (urticaria, angioedema). In this case, the use of the drug is stopped and antihistamines are prescribed.
Use during pregnancy and breastfeeding
Used only if the expected benefit to the mother outweighs the potential risk to the fetus and child.
Interaction
When used simultaneously with external dosage forms of erythromycin, clindamycin, lincomycin and gentamicin, the effect is mutually weakened.
Overdose
Unlikely due to low absorption. When applying the ointment to large surfaces and long-term treatment, symptoms of the hematopoietic system may appear - anemia, leukopenia, thrombocytopenia, reticulocytopenia, which usually disappear after stopping the drug and prescribing symptomatic therapy.
Impact on the ability to drive vehicles and operate machinery
The drug does not affect the ability to engage in potentially hazardous activities that require special attention and quick reactions (driving a car and other vehicles, working with moving mechanisms, working as a dispatcher and operator, etc.).
How to treat hemorrhoids with Levomekol
Thanks to the use of Levomikol for hemorrhoids, significant success can be achieved. Since the medicine has an antimicrobial and antibacterial effect, it effectively fights infectious agents.
There is also a decrease in pain, inflammation, swelling and itching. Leniment promotes drying of tissues and stimulates their regeneration.
Treatment of hemorrhoids is carried out in the following order:
- The anus is washed with water at room temperature.
- Dry with a towel.
- Apply the ointment to the area of the nodes before going to bed.
- The anal area is covered with a clean cloth.
- The duration of the course of therapy is no more than 10 days.
Is it possible to use Levomekol on a wound?
The ointment is widely used for the regeneration of clean wound surfaces and purulent discharge. It helps eliminate pathogens, helps reduce inflammation, swelling and prevents further skin infections.
Leniment is preferably applied at night. If the wound is clean, it is treated with an antiseptic solution and a thin layer of ointment. A bandage is applied on top. When the wound surface suppurates, turundas with an antiseptic are placed into its cavity to absorb pus and secretions. Afterwards, Levomikol is placed and fixed with a napkin soaked in the medicine.
How to use Levomekol for burns
Due to the unique composition of leniment, it has pronounced antimicrobial and antibacterial properties. Increases local immunity, which is especially important for burns. In addition, it suppresses the effect of viruses, stimulates the restoration of tissue cells, relieves inflammation and prevents the necrotic process.
To treat burns, the damaged area is washed with an antiseptic solution and covered with a napkin containing Levomikol. The dressing is changed up to 5 times a day.
The drug is used for varying degrees of burns. The duration of the course of treatment is determined by the doctor.
Levomethyl 30g ointment for external use
pharmachologic effect
A combined preparation for external use that has anti-inflammatory (dehydrating) and antimicrobial effects. Chloramphenicol disrupts the process of protein synthesis in the microbial cell and is a bacteriostatic antibiotic. Active against gram-positive and gram-negative microorganisms (staphylococci, Pseudomonas aeruginosa and Escherichia coli, etc.). Easily penetrates deep into tissues without damaging biological membranes. In the presence of pus and necrotic masses, the antibacterial effect remains. Dioxomethyltetrahydropyrimidine, normalizing nucleic acid metabolism, stimulates regeneration processes in wounds, growth and granulation maturation of tissue, epithelization, and has an anti-inflammatory (dehydrating) effect.
Composition and release form Levomethyl 30g ointment for external use
Ointment - 100 g:
- Active ingredients: chloramphenicol (chloramphenicol) - 0.75 g; dioxomethyltetrahydropyrimidine (methyluracil) - 4.0 g;
- Excipients: macrogol 400 (polyethylene oxide 400) - 76.2 g, macrogol 1500 (polyethylene oxide 1500) - 19.05 g.
Ointment for external use in aluminum tubes of 30.0 g. Each tube, together with instructions for medical use, is placed in a cardboard box.
Description of the dosage form
The ointment is white or white with a yellowish tint.
Directions for use and doses
A strip of ointment with a diameter of 5 mm and a length of 1 cm has an average mass of 0.3 g, which corresponds to 10 mg of chloramphenicol and 20 mg of dioxomethyltetrahydropyrimidine. For adults and children, the drug is applied once a day directly to damaged areas of the skin at the rate of 0.3 g per 1 cm2 of the wound surface or applied to sterile gauze napkins at the rate of 0.3-0.6 g per 1 cm2 of the wound surface, cover the damaged area with a napkin area of skin and secure with a bandage. The daily dose of ointment in terms of chloramphenicol should not exceed 3 g of chloramphenicol.
Pharmacokinetics
The drug is absorbed slightly and does not have a systemic effect.
Indications for use Levomethyl 30g ointment for external use
Purulent wounds (including those infected with mixed microflora) in the first (purulent-necrotic) phase of the wound process.
Contraindications
Hypersensitivity, skin mycoses, dermatitis, eczema, psoriasis.
With caution: pregnancy, lactation, children under 1 year.
Application of Levomethyl 30g ointment for external use during pregnancy and breastfeeding
Used only if the expected benefit to the mother outweighs the potential risk to the fetus and child.
special instructions
When applied to large areas of skin and long-term courses of treatment, it is necessary to conduct a clinical blood test.
The drug does not affect the ability to engage in potentially hazardous activities that require special attention and quick reactions (driving a car and other vehicles, working with moving mechanisms, working as a dispatcher and operator, etc.).
Overdose
Unlikely due to low absorption. When applying the ointment to large surfaces and long-term treatment, symptoms of the hematopoietic system may appear - anemia, leukopenia, thrombocytopenia, reticulocytopenia, which usually disappear after stopping the drug and prescribing symptomatic therapy.
Side effects of Levomethyl 30g ointment for external use
Allergic reactions (urticaria, angioedema). In this case, the use of the drug is stopped and antihistamines are prescribed.
Drug interactions
When used simultaneously with external dosage forms of erythromycin, clindamycin, lincomycin and gentamicin, the effect is mutually weakened.
