Compound
D-Panthenol ointment for external use - dexpanthenol, lanolin , phenonip, beeswax, white paraffin, emulsifier, dietetics, propylene glycol, butylated hydroxyanisole, decamethylcyclopentasiloxane, butylated hydroxytoluene, protegin B, magnesium sulfate heptahydrate, purified water. Cream D-Panthenol 5% for external use - dexpanthenol, cetearyl octanoate, ketomacrogol, methyl parahydroxybenzoate, cetanol, propylene glycol, dimethicone, glyceryl monostearate, propyl parahydroxybenzoate, purified water, flavoring.
Description of the drug, its properties
Panthenol is a drug for external use, which is intended to restore the skin after various injuries.
Action of the product:
- eliminates pain;
- stops inflammation if it has not become infectious;
- normalizes metabolism, thereby activating the process of appearance of new skin cells;
- eliminates flaking and moisturizes the skin.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Dexpanthenol is a derivative of pantothenic acid, which belongs to the B vitamins (water-soluble) that are part of coenzyme A. It plays an important role in metabolic processes: the breakdown of fatty acids, the release of energy from carbohydrates, the synthesis of sterols, acetylcholine, and steroid hormones. Pantothenic acid supports the functions of the epithelium, and in cases of damage to the skin or mucous membranes, there is an increased need for it. The drug stimulates the skin regeneration process, increases the strength of collagen fibers, normalizes cellular metabolism, and has a slight anti-inflammatory effect. Hydrophilicity, optimal molecular weight and low polarity of these drugs allow the active substance to penetrate into all layers of the skin. The auxiliary substances included in the ointment and cream improve the trophism of the skin and soften it.
Pharmacokinetics
The drug is quickly absorbed from the surface of the skin, and the active substance binds to blood proteins (albumin and beta globulin).
Contraindications
Intolerance to dexpanthenol or the auxiliary components contained in the drug.
Parenteral administration and taking tablets are contraindicated in cases of mechanical intestinal obstruction and hemophilia .
Additional contraindications for the tablets are childhood, glucose/galactose malabsorption syndrome , fructosemia , sucrose-isomaltase deficiency .
Indications for use
- various violations of the integrity of the skin formed under the influence of mechanical, temperature and chemical factors ( burns of various origins, bedsores , abrasions, scratches, superficial wounds, long-healing skin grafts);
- aseptic postoperative wounds after surgery;
- boils , dermatitis , inflammatory processes on the skin, trophic ulcers of the extremities, inflammation and cracked nipples in nursing mothers, lower skin care near tracheostomy , colostomy , gastrostomy ;
- in children - scratches, diaper dermatitis , irritation after ultraviolet radiation, for the prevention and treatment of diaper rash ;
- prevention and treatment of the consequences of exposure to various adverse environmental factors (humidity, wind, cold) on the skin.
Instructions for use of D-Panthenol (Method and dosage)
D-Panthenol ointment, instructions for use: the ointment is applied externally in a thin layer to the skin in the affected area, lightly rubbing in, 2-4 (more often if necessary) times a day. If the skin area is infected, it is necessary to pre-treat it with an antiseptic. For breastfeeding women, lubricate the nipple with ointment after each feeding of the baby. Depanthenol ointment can also be used by children, including children under one year of age. For newborns, the ointment is applied after each water procedure or change of linen. The duration of use of the ointment is determined by the tolerability of the drug and the effectiveness of treatment.
Instructions for D-Panthenol cream: apply the cream externally to adults and children in a thin layer on the skin in the affected area, lightly rubbing in, 2–4 (more often if necessary) times a day, 2–4 times a day. If the skin area is infected, it is necessary to pre-treat it with an antiseptic. For nursing mothers who have cracked nipples, apply Depanthenol cream after each feeding of the baby. To treat damaged cervical mucosa and anal fissures and pathologies, it is enough to lubricate the affected areas 1-2 times a day.
It should be remembered that De-Panthenol ointment and cream are not recommended to be applied to weeping wounds. All forms of the drug are safe during pregnancy and lactation, both for the mother and the fetus.
Interaction
When used locally according to indications, interaction with other drugs is unknown.
When applying the spray to the anal area or genitals in the case of using condoms, it reduces the strength of the latter when breaking. This is due to the fact that this dosage form of the drug contains mineral oil.
There is evidence that dexpanthenol, when taken orally and parenterally, prolongs the effects of succinylcholine .
The use of an injection solution in combination with general anesthesia, barbiturates and antibacterial drugs increases the risk of developing hypersensitivity reactions.
Analogs
Level 4 ATC code matches:
Panthenol
Kalanchoe juice
Aloe liniment
Levomekol
Pantestin-Darnitsa
Dexpanthenol
Contractubex
Pantoderm
Bepanten
Structural analogues by ATC code and active substance: Bepanthen ; Dexpanthenol ; Panthenol Pharmstandard; Korneregel ; Panthenol-ratiopharm ; Moreal-plus ; Panthenol ; Panthenolspray ; Pantoderm .
Reviews about D-Panthenol
Reviews about D-Panthenol ointment are overwhelmingly positive. “...I used D-Panthenol for acne yesterday. Today there is nothing left even to the touch, the skin is a pleasant color. I was even a little scared, maybe it was a hormonal drug. I used them before and the effect was good, but I was advised not to use hormonal drugs. I recommend". Many patients use De-Panthenol ointment for skin burns and note the high effectiveness of this form of the drug. But, nevertheless, for burns it is better to use depanthenol cream or D-Panthenol spray (correctly - Panthenol spray), which helps well with minor thermal and sunburns.
Reviews about D-Panthenol cream are also good. “...I first became acquainted with Depanthenol when I scalded my hand. The neighbor applied cream to the burn and three days later I didn’t even remember about the burn. The second time was when my hand was cut. I cut the bread poorly. And the cream also helped a lot. The healing took a little longer this time, but the result was good. Now depanthenol cream has taken its place in my home medicine cabinet.”
Many patients are interested in which form of the drug is more effective: “for what is it better to use ointment, and for what is it better to use cream?” The choice of the form of the medicine depends on the nature of the skin of the damaged surface: the ointment contains a higher percentage of fat and the use of depanthenol ointment is recommended for dry skin in the patient. The cream does not contain fat and the use of depanthenol cream is recommended on open areas of the body and on wet wounds. In addition, d panthenol cream is easily rubbed in and quickly absorbed, so it is recommended to use it for minor burns, in particular for sunburns.
Also, many patients are interested in D-Pantol suppositories, however, some of them mistakenly search for the drug using the query “depanthenol suppositories” and do not find this dosage form. You need to look for Depantol suppositories, not Depanthenol. This dosage form is widely used in gynecology. In addition to dexpanthenol, it contains chlorhexidine bigluconate, which has pronounced antimicrobial activity, as well as dermatophytes, yeast and protozoa. Has antimicrobial, regenerating and metabolic effects.
Often on the Internet, when discussing D-Panthenol ointment and what it is best used for, you can come across recommendations for using panthenol for hair. This is true, since Panthenol has an extremely beneficial effect on hair of any type, restoring damaged structure and nourishing it. Panthenol prevents fragility, dryness, splitting and splitting, increases the scalp's resistance to negative and damaging factors, eliminates itching, and stimulates hair growth. However, in this case, it is recommended not to use Panthenol spray, but to take the drug orally in the form of capsules (Panthenol-40), which is prescribed for hair loss, splitting and brittleness, dandruff, impaired hair growth, and increased production of sebaceous glands.
special instructions
When using the drug, you should consider the following features:
- the product does not help fight purulent wounds, in which case more effective drugs will be needed;
- if the surface of the damaged skin constantly gets wet, then there is no point in using the product;
- Panthenol can provoke an allergic reaction, so before use you should apply a little product to a healthy area of skin and wait a day. If there is no reaction, then you can use it for its intended purpose.
The drug is allowed to be used by pregnant women. It is absolutely non-toxic, intended for external use and is not able to penetrate the bloodstream or affect organs. Panthenol will not affect the health of the expectant mother and her baby in any way.
D-Panthenol price, where to buy
How much does De-Panthenol ointment cost in Russia and Ukraine? The price of Depanthenol ointment in Russia varies between 246 -375 rubles per package. The cost of the cream in a 30 g tube is, on average, 232 rubles per package. The spray in a 200 ml bottle can be purchased for 676 rubles. The price of D-Panthenol ointment in Ukraine is 246 UAH. The price of D-Panthenol cream is 278 hryvnia per package. You can buy Depanthenol cream in most pharmacies in Moscow and the pharmacy chain in Ukraine.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
ZdravCity
- D-Panthenol-Nizhpharm cream for external use.
appl. 5% tube 25 gAO "Nizhpharm" 210 rub. order - D-Panthenol-Nizhpharm cream for external use. appl. 5% tube 50 gAO "Nizhpharm"
RUB 327 order
- D-Panthenol-Nizhpharm ointment for external use. approx. 5% tube 30g Hemofarm A.D.
260 rub. order
- Antiseptic hand gel for children with D-panthenol Klinsa 60ml ZAO NPO Khimsintez
81 RUR order
- D-Panthenol-Nizhpharm-Plus cream for external use. appl. tube 30 gAO "Nizhpharm"
290 rub. order
Pharmacy Dialogue
- Dexpanthen plus* (cream with D-panthenol 6% and decamethoxin 50g) Twins Tech
RUR 348 order
- Dexpanthen baby* (cream with D-panthenol 6%/beeswax 50g) Twins Tech
RUB 269 order
- D-panthenol-Nizhpharm ointment (tube 30g) Hemofarm LLC
250 rub. order
- D-panthenol-Nizhpharm-Plus cream (tube 30g)Nizhpharm JSC
RUB 284 order
- D-Panthenol Novatenol cream (tube 5% 50g) Jadran-Galenski
RUR 429 order
show more
Pharmacy24
- Aqua Spray + D-Panthenol 45 ml spray PAT"Khimpharmzavod"Chervona Zirka",Kharkiv, Ukraine
69 UAH.order - “Children’s” with D-panthenol 100 ml cream OOO NPL Fitoprodukt, Ukraine
15 UAH order
- Aqua Spray + D-Panthenol 0.65% 150 ml nasal spray PAT"Khimpharmzavod"Chervona Zirka",Kharkiv, Ukraine
130 UAH order
Release form
- Tablets 100 mg No. 20 or No. 50.
- Solution for injection 250 mg/ml (ampoules 2 ml, package No. 10).
- Aerosol 5% 58 or 116 g (aluminum containers).
- Ointment 50 mg/g (tubes of 30 g).
- Skin foam (spray) 46.3 mg/g (pressure containers 130g, package No. 1).
- Gel 7% 75 ml.
- Lotion 10% 200 ml.
- Panthenol cream 5% (46 ml tubes).
- Gelatin capsules 40 mg.
- Body milk 3% 200 ml.
In addition, suppositories with Panthenol are produced for rectal and vaginal use and a nasal spray with dexpanthenol (the drug Moreal-plus ).
Dexpanthenol can be found not only in medicines, but also in cosmetics - in creams for face and body care, milk, serums, balms, shampoos, hair masks, caring and decorative varnishes.
