Rinonorm-Teva nasal spray dosed 0.05%, 20ml

Composition of Rinonorma

Depending on the type of nasal spray Rinonorm, the composition is 10 ml. of this medicine may contain either 5 mg. (for children) or 10 mg. (for adults) the active substance xylometazoline hydrochloride .
In addition, the preparation contains such auxiliary compounds as: 85% glycerol , citric acid monohydrate, sodium citrate dihydrate, as well as water intended for injection.

RINONORM (spray)

generally funny, something like 49 rubles, if my memory serves me right, and the composition, with the drug mentioned above, is the same.
I decided to try it. Teva “Rinonorm-Teva” nasal spray for children (the price, as you can see, has also begun to rise, and speaking of price, the difference between the children’s and adult’s drug is a couple of rubles):

This is what an adult looks like, practically no different, except for the dosage and the design on the box (the price indicated, as you can see, is two rubles higher):

The spray comes in a box, like almost everything now. The box contains minimal information - composition and manufacturer, expiration date and series are printed on top. That's all, the rest of the information is contained in the instructions that come with the spray.

Country of origin: Germany:

The composition is standard (children and adults differ only in the dosage of xylometazoline hydrochloride):

Best before date:

For anyone interested, I have attached the instructions, they are standard:

The jars themselves with the drug are dark brown in color, protected from the sun, and they have a cool idea that the caps covering the dispensing hole are of different colors - orange for children, yellow for adults. This prevents you from getting confused in the application when in the dark, using your phone’s light or quickly taking the drug from the shelf, you don’t need to look at the dosage, but simply take the desired color jar with a cap. It’s just a mega-cool (so I’ll put it) idea, I saw it for the first time, and I would recommend it to all manufacturers, even my child knows what and whose nasal spray is where. This cap is also rubberized or silicone, very pleasant to the touch, and the spout itself, with which you spray the spray, is soft, and there have been cases when the mucous membrane inside the nose was damaged due to the fact that it is made of hard plastic. In general, the design of the jar itself is 10 out of 10. These are the ones for children with orange caps:

I used the children's ones to the last drop, in the truest sense of the word.

Here are the adult jars with yellow caps:

And I have a new adult:

This is what the cap and spout look like:

The pressure of the spray works perfectly, the required amount of the drug is distributed, not a single jar has ever failed, it is natural that the pressure mechanism works perfectly for everyone (and by the way, the drug is used up to the last drop, there is none left):

Now about the pros, there are absolutely no cons:

+ The first plus is the packaging, as you understood from the description above. Here I have no complaints at all, from the box without unnecessary information and water, to the jar, which is made perfectly, this spray is a pleasure to use.

+ The second plus is the result. In principle, the composition is no different from many other drugs, but naphthyzine just doesn’t help me as much as these drugs, I can’t name the reason. The main thing is that this spray from Tev works great for my nose.

Why do I have so many jars, don’t be alarmed, I’m not a drug addict, and I got rid of a twelve-year drip addiction three years ago. I’m just going through a period of hay fever, and it’s like there’s no choice, I have to accept everything.

For me, these drops even broke through the most active days of hay fever, when even the hormonal nasal allergy medication did not help me during the period of hay fever, this is such a strange situation.

And against viral rhinitis, during the period of acute respiratory infections, it helps with a bang. By the way, I have a great taste for children's spray, and that's why I buy it (this means that all these jars are mine, not the child's), because it breaks through, then why take a large dosage.

+ A price that, although it has begun to rise rapidly, is still affordable.

I don’t need any more advantages, it gave me everything I expect from such drugs. 10 out of 10 is my rating. I am pleased!!!

I recommend!!!

This is my squad:

Pharmacodynamics and pharmacokinetics

This nasal spray is actively used for topical use in the practice of ENT doctors. the xylometazoline contained in the drops is an alpha-adrenergic agonist, this active compound helps to constrict arterioles , which has a beneficial effect on the nasopharyngeal mucosa by reducing swelling and eliminating hyperemia.

Rinonorm helps reduce the amount of secretions within a few seconds after topical application. The medicinal effect of the drops lasts for several more hours. The medicine restores the patency of the nasal passages, Eustachian tubes, and also the openings of the sinuses.

Under the influence of nasal drops, the well-being of patients significantly improves by restoring the air patency of the nasopharynx , and also reduces the likelihood of developing complications that inevitably arise with prolonged stagnation of secretions.

on the use of a medicinal product for medical use RINONORM COMFORT

Registration number:

LP-006693

Tradename:

Rinonorm Comfort

International Nonproprietary Name (INN):

Xylometazoline+dexpanthenol

Dosage form:

dosed nasal spray [for children]

Compound

1 dose of the drug contains: active ingredients: xylometazoline hydrochloride 0.100/0.050 mg, dexpanthenol 5.000 mg; excipients: sodium hydrogen phosphate heptahydrate (disodium phosphate heptahydrate) 0.0225 mg, potassium dihydrogen phosphate 0.855 mg, water for injection 95.322/95.372 mg.

Description

Transparent almost colorless solution.

Pharmacological group:

decongestant

ATX code:

R01AB06

Pharmachologic effect:

Xylometazoline belongs to the group of local vasoconstrictors (decongestants) with alpha-adrenomimetic activity, causes constriction of the blood vessels of the nasal mucosa, restores the patency of the nasal passages, and facilitates nasal breathing. The effect of the drug usually occurs within a few minutes after its use and lasts up to 10 hours.

Dexpanthenol is a B vitamin and is a derivative of pantothenic acid. Dexpanthenol is converted in the body into pantothenic acid, which is an integral part of coenzyme A and is involved in the processes of acetylation, carbohydrate and fat metabolism, in the synthesis of acetylcholine, corticosteroids, porphyrins; stimulates the restoration of skin and mucous membranes, normalizes cellular metabolism, accelerates mitosis and increases the strength of collagen fibers. It has a regenerating, metabolic and mild anti-inflammatory effect.

Pharmacokinetics:

Xylometazoline is practically not absorbed when applied topically; plasma concentrations are so low that their determination by modern analytical methods is impossible.

When applied topically, dexpanthenol is quickly absorbed by the mucous membrane, converted into pantothenic acid, and binds to blood plasma proteins (mainly beta-globulin and albumin). Its concentration in the blood is 0.5-1 mg/l, in the blood serum - 100 μg/l. Pantothenic acid is not metabolized (except for inclusion in Co-A) and is excreted unchanged.

Indications for use:

Used for acute respiratory diseases with symptoms of rhinitis, acute allergic rhinitis, vasomotor rhinitis, sinusitis, otitis media (as part of combination therapy to reduce swelling of the nasopharyngeal mucosa), to facilitate rhinoscopy, restoration of impaired nasal breathing after surgical interventions in the nasal cavity.

Contraindications:

• - hypersensitivity to the components of the drug
• - arterial hypertension
• - tachycardia
• - severe atherosclerosis
• - atrophic rhinitis
• - dry rhinitis
• - hyperthyroidism
• - porphyria
• - prostatic hyperplasia
• - glaucoma
• - surgical interventions on the meninges (history), simultaneous use with monoamine oxidase inhibitors (MAO) and tricyclic antidepressants, pregnancy, breastfeeding

Carefully:

Diabetes mellitus, pheochromocytoma, diseases of the cardiovascular system (including coronary heart disease), increased sensitivity to the action of adrenergic drugs, accompanied by insomnia, dizziness, arrhythmia, tremor, increased blood pressure.

Directions for use and doses

Intranasally.

For dosage 0.1 mg + 5 mg/dose

- adults and children over 6 years old, one injection into each nasal passage 3-4 times a day. Duration of therapy is 5-7 days.

For dosage 0.05 mg + 5 mg/dose

- for children from 2 to 6 years old, one injection into each nasal passage 3-4 times a day. Duration of therapy is 5-7 days.

Should not be used for more than 7 days. The duration of use of the drug in children is determined after consultation with a doctor.

Repeated use is possible only after a break of several days.

If after 5 days of treatment there is no improvement or the symptoms worsen or new symptoms appear, you should consult your doctor. Use the drug only according to the indications, method of administration and in the doses indicated in the instructions.

Mode of application

• — Remove the protective cap;
• — Before first use, press the pump dispenser several times until a uniform spray appears;
• — Hold the bottle upright, insert the tip of the dispensing device into the nasal passage and press once. During injection, you need to inhale lightly through your nose;
• — After use, thoroughly wipe the dispenser tip with a clean cloth and close the protective cap.

Side effect:

The following adverse events are systematized according to the World Health Organization (WHO) Classification: very common (≥1/10), common (≥1/100 and <1/10), uncommon (≥1/1000 and <1/100) , rare (≥1/10000 and <1/1000), very rare (<1/10000); unknown (cannot be determined based on available data).

From the immune system:

very rarely - allergic reactions (skin rash, itching, angioedema).

From the nervous system:

very rarely - headache, anxiety, insomnia, fatigue (drowsiness), hallucinations (mainly in children).

From the cardiovascular system:

rarely - palpitations, tachycardia, increased blood pressure; very rarely - arrhythmia.

From the respiratory system, chest and mediastinal organs:

very rarely - swelling of the nasal mucosa, hypersecretion, nosebleeds. frequency unknown - burning and dryness of the nasal mucosa, sneezing.

From the musculoskeletal system:

very rarely - convulsions (mainly in children).

If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.

Interaction with other drugs:

Concomitant use of MAO inhibitors and tricyclic antidepressants may lead to an increase in blood pressure due to the effects of these drugs on the cardiovascular system.

Special instructions:

Before use, it is necessary to clean the nasal passages.

The duration of use of the drug in children is determined after consultation with a doctor.

Patients with long QT syndrome using xylometazoline may be at increased risk of developing serious ventricular arrhythmias.

Impact on the ability to drive vehicles and machinery

When using the drug in accordance with these instructions for use, the drug does not affect the ability to drive vehicles or machines, however, if adverse events occur, you should refrain from performing these types of activities.

Release form

Nasal spray dosed, 0.1 mg + 5 mg/dose, 0.05 mg + 5 mg/dose.

10 ml (90 doses) in a polymer bottle (high density polyethylene) with a dispensing device for spraying, sealed with a protective cap.

1 bottle along with instructions for use in a cardboard box, on which additional protective stickers can be applied.

Storage conditions:

At a temperature not exceeding 25 ° C in the original packaging (bottle in a pack).

Keep out of the reach of children!

Best before date

3 years.

After opening the bottle, the drug is suitable for use for 6 months.

Do not use after the expiration date.

Conditions for dispensing from pharmacies:

Available without a prescription.

Name of the holder (owner) of the registration certificate of the medicinal product

Teva Pharmaceutical Enterprises Ltd., Israel.

Manufacturer

Merkle GmbH, Ludwig-Merkle-Strasse 3, 89143 Blaubeuren Germany.

Organization receiving consumer complaints:

Teva LLC, 115054, Moscow, st. Valovaya, 35, tel.: +7 (495) 644 22 34, fax

Internet address: www.teva.ru

Indications for use

Rinonorm is indicated for use in the therapeutic treatment of rhinitis (allergic, bacterial or viral), sinusitis (in acute or chronic acute phases), as well as to eliminate swelling of the mucous membranes of the Eustachian tube in otitis media . In addition, drops are used as a preparatory agent before carrying out diagnostic manipulations in the nasal passages.

Rinonorm-Teva 0.05% nasal spray for children from 2 to 10 years old 20ml

Rinonorm-Teva for children - instructions for use

Prices / buy Analogs, articles Comments Indications Contraindications Dosage Warnings Interactions Manufacturer
Registration number:
P N014799/02 dated 04/24/2009
Trade name of the drug:
Rinonorm-Teva
International nonproprietary name:
Xylometazoline
Dosage form:
dosed nasal spray [for children]
Composition:
100 ml the drug contains: active substance: xylometazoline hydrochloride 0.050 g;
excipients: benzalkonium chloride (in the form of a 50% solution) 0.040 g in terms of benzalkonium chloride 0.020 g, citric acid monohydrate 0.050 g, sodium citrate dihydrate 0.260 g, glycerol 85% 2.400 g, purified water up to 100 ml. Description:
Transparent colorless solution.
Pharmacotherapeutic group:
anticongestive agent - alpha-adrenergic agonist.
ATC code:
R01AA07
Pharmacological properties
Xylometazoline is an alpha-adrenergic agonist used for topical use in ENT practice.
When applied topically, xylometazoline causes constriction of arterioles, which leads to a decrease in hyperemia and swelling of the mucous membranes of the nasopharynx and a decrease in secretion. A distinct local effect of the drug is detected within a few minutes and persists for several hours (up to 6-8 hours), manifesting itself in the restoration of patency of the nasal passages, sinus openings and eustachian tubes. Restoring the air patency of the nasopharynx improves the well-being of patients and reduces the risk of possible complications caused by stagnation of mucous secretions. Pharmacokinetics: When applied topically, xylometazoline is practically not absorbed, so plasma concentrations are very low (not analytically determined). Indications for use
As a symptomatic treatment for the following diseases and conditions: acute viral or bacterial rhinitis;
acute allergic rhinitis; acute sinusitis or exacerbation of chronic sinusitis; acute otitis media (to reduce swelling of the mucous membrane of the Eustachian tube); preparing patients for diagnostic procedures in the nasal passages. Contraindications:
hypersensitivity to xylometazoline or other components of the drug;
inflammation of the skin, nasal mucosa and crust formation (dry rhinitis); use after hypophysectomy; use in children under 2 years of age; angle-closure glaucoma; taking monoamine oxidase inhibitors (MAO) and tricyclic antidepressants. with caution
in patients with hypertension, severe heart disease, hyperthyroidism and diabetes mellitus.
Method of administration and dosage
Children from 2 to 10 years: 1 dose (one press on the piston device) in each nasal passage no more than 3 times a day (the maximum dose should not exceed 7 times a day).
The interval between drug administration should not be less than 6 hours. 1 dose = 0.07 ml solution, 35 mcg. To avoid complications in the form of resumption of symptoms of the disease, the duration of continuous use of the drug should not exceed 7 days. Before using the drug Rinonorm-Teva, it is recommended to clear the nasal passage of secretions, and during the administration of the drug it is necessary to take a light breath through the nose. For use in adults and children over 10 years of age, use the drug Rinonorm-Teva, a dosed nasal spray. Side effect
: Burning sensation and dryness of the nasal mucosa;
in rare cases - irritation of the nasal mucosa, oral cavity and larynx, headache and nausea; extremely rare ([1/10000) - arrhythmia, increased blood pressure, increased excitability, skin reactions. Overdose
In rare cases of overdose, occurring mainly in children, the following symptoms may be observed: irregular pulse, increased blood pressure, and in some cases, loss of consciousness.
In case of overdose, symptomatic treatment under supervision is indicated. In serious cases, non-selective alpha-blockers may be used to lower blood pressure, as well as intubation and mechanical ventilation. Vasoconstrictor drugs are contraindicated. If you accidentally take a moderate or large amount of the drug orally, you should take activated carbon (adsorbent) and sodium sulfate (laxative), and do a gastric lavage. Interaction with other drugs:
Concomitant use of tri- or tetracyclic antidepressants may increase the systemic exposure of xylometazoline.
When taking the drug simultaneously with monoamine oxidase inhibitors (MAOIs), there may be a risk of increased blood pressure. Special instructions
No effects on the ability to drive vehicles or control machines and mechanisms were noted.
Release form:
Dosed nasal spray [for children] 0.05%.
15 ml or 20 ml in a dark glass bottle with a dispensing device for spraying, a nasal nozzle and a protective cap. 1 bottle along with instructions for use in a cardboard box. Storage conditions
Store at a temperature not exceeding 25C.
Keep out of the reach of children! Shelf life:
2 years.
Do not use after the expiration date. Conditions of release
Dispensed without a prescription.
Manufacturer
1. Merkle GmbH, Ludwig-Merkle-Strasse 3, 89143, Blaubeuren, Germany 2. Merkle GmbH, Graf-Arco-Strasse 3, 89079 Ulm, Germany
Legal entity in whose name the RU was issued Teva Pharmaceutical Enterprises Ltd.,
Israel
Claims consumers should be sent to the address: 115054, Moscow, st.
Valovaya, 35. May 27, 2022

The appearance of the product may differ from the photographs on the website.

Information about medications posted on the site is intended for specialists and includes materials from publications from different years. The information provided on the site is general and is presented for informational purposes only, does not replace consultation with a doctor and cannot serve as a guarantee of the positive effect of the drug. Tvoyaapteka.rf warns you about possible negative consequences that may arise as a result of incorrect use of the information presented on the site and strongly recommends that you consult with a specialist before choosing a drug.

You can find detailed and up-to-date instructions for the drug on the website of the State Register of Medicines www.grls.rosminzdrav.ru.

Contraindications Rinonorma

Absolute contraindications for Rinonorm include the following cases:

• dry or atrophic rhinitis;
• angle-closure glaucoma;
• patient age under 2 years;
• hypersensitivity to the main and auxiliary components of the drug compound.

It is not recommended to use these nasal drops in conditions following hypophysectomy , as well as when taking tricyclic antidepressants and MAO inhibitors ( monoamine oxidase ).

Side effects

Quite rarely, however, the following side effects may occur:

• increased excitability;
• headache;
• increased blood pressure;
• arrhythmia;
• insomnia;
• nausea;
• irritation of mucous membranes;
• burning or itching;
• skin rashes.

Rinonorm, instructions for use (Method and dosage)

Instructions for use of Rinonorm differ depending on the type of drops. A children's spray containing a 0.05% xylometazoline solution is prescribed one dose (equivalent to one press of the dispenser - 0.14 ml) into each nostril no more than three times a day.

For adult patients, as well as children over the age of 10 years, a drug containing 0.1% xylometazoline is prescribed in a dosage equal to one press on the piston device in each nostril no more than three times a day.

The total duration of use of the medicine should not exceed seven days. It is advisable to maintain a six-hour interval between the use of drops. To enhance the effectiveness of the spray, it is worth clearing the nasal sinuses of secretions before using it.

Rinonorm-Teva nasal spray dosed 0.05%, 20ml

Registration Certificate Holder

ratiopharm (Germany)

Dosage form

Medicine - Rhinonorm

Description

Dosed nasal spray (for children) 0.05%

in the form of a clear, colorless solution.

1 ml

xylometazoline hydrochloride 500 mcg

Excipients

: citric acid monohydrate, sodium citrate dihydrate, glycerol 85%, liquid water.

10 ml - dark glass bottles (1) with a dispensing device and a nosepiece - cardboard packs. 15 ml - dark glass bottles (1) with a dispensing device and a nosepiece - cardboard packs.

Indications

Rinonorm is used as symptomatic therapy for the following diseases and conditions:

• acute viral or bacterial rhinitis;
• acute allergic rhinitis;
• acute sinusitis or exacerbation of chronic sinusitis;
• acute otitis media (to reduce swelling of the mucous membrane of the Eustachian tube);
• preparing the patient for diagnostic procedures in the nasal passages.

Contraindications for use

• atrophic (dry) rhinitis;
• angle-closure glaucoma;
• condition after hypophysectomy;
• simultaneous use of MAO inhibitors and tricyclic antidepressants;
• children under 2 years of age (for spray for children);
• children under 10 years of age (for adult spray);
• hypersensitivity to xylometazoline or other components of the drug.

Carefully _

The drug should be used for arterial hypertension, severe heart disease, hyperthyroidism, diabetes mellitus and in patients taking bromocriptine.

pharmachologic effect

Alpha adrenergic agonist for local use in ENT practice.

When applied topically, xylometazoline causes constriction of arterioles, leading to a decrease in hyperemia and swelling of the mucous membranes of the nasopharynx and a decrease in secretion. A distinct local effect of the drug is detected within a few minutes and persists for several hours (up to 6-8 hours), manifesting itself in the restoration of patency of the nasal passages, sinus openings and Eustachian tubes. Restoring air patency of the nasopharynx improves the patient’s well-being and reduces the risk of possible complications caused by stagnation of mucous secretion.

Drug interactions

Concomitant use of tri- or tetracyclic antidepressants may increase the systemic exposure of xylometazoline.

When taking the drug simultaneously with MAO inhibitors, there may be a risk of increased blood pressure.

Dosage regimen

Adults and children over 10 years old

Prescribe Rinonorm nasal spray 0.1%, 1 dose (1 press on the piston device) in each nasal passage no more than 3 times a day.

Children aged 2 to 10 years

Prescribe Rinonorm nasal spray for children 0.05%, 1 dose (1 press on the piston device) in each nasal passage no more than 3 times a day.

The maximum possible use of the drug is no more than 7 times a day. The interval between drug administration should not be less than 6 hours.

The amount of liquid entering the patient’s nasal passage (1 dose) is 0.14 ml of solution.

To avoid complications in the form of resumption of symptoms of the disease, the duration of continuous use of the drug should not exceed 7 days.

Before using the drug, you should clear the nasal passages of secretions. During administration of the drug, you should take a light breath through the nose.

Overdose

Symptoms

: in rare cases of overdose, occurring mainly in children, arrhythmia, increased blood pressure, and in some cases loss of consciousness may be observed.

Treatment:

symptomatic therapy under supervision is indicated. In serious cases, non-selective alpha-blockers can be used to lower blood pressure, as well as intubation and mechanical ventilation. Vasoconstrictor drugs are contraindicated. If you accidentally ingest a moderate or large amount of the drug, you should take activated charcoal and a laxative (for example, sodium sulfate), and do a gastric lavage.

Side effect

Local reactions:

burning sensation and dryness of the nasal mucosa; rarely - irritation of the mucous membrane of the nose, mouth and larynx.

From the side of the central nervous system:

rarely - headache;
extremely rarely (< 1/10,000) - insomnia, increased excitability. From the cardiovascular system:
extremely rarely (< 1/10,000) - arrhythmia, increased blood pressure.

Other: rarely - nausea; extremely rare (<1/10,000) - skin reactions.

special instructions

Impact on the ability to drive vehicles and operate machinery

There was no effect on the ability to drive vehicles or control machines and mechanisms.

Storage conditions

The drug should be stored out of the reach of children at a temperature not exceeding 25°C.

Best before date

Shelf life - 3 years, after opening the bottle - 1 year.

Use during pregnancy and breastfeeding

Restrictions during pregnancy - Contraindicated. Restrictions when breastfeeding - With caution.

The drug should not be taken during pregnancy.

The drug should be used with caution during breastfeeding.

Use in children

Restrictions for children - With caution.

Children aged 2 to 10 years

Prescribe Rinonorm nasal spray for children 0.05%, 1 dose (1 press on the piston device) in each nasal passage no more than 3 times a day.

Adults and children over 10 years old

Prescribe Rinonorm nasal spray 0.1%, 1 dose (1 press on the piston device) in each nasal passage no more than 3 times a day.
Contraindication: children under 2 years of age (for spray for children), children under 10 years of age (for spray for adults).
Terms of sale

The drug is approved for use as a means of OTC.

Contacts for inquiries

TEVA (Israel)

Teva LLC

115054 Moscow Valovaya st. 35 Business Tel.

Analogues of Rinonorm

Level 4 ATX code matches:
Xymelin Eco

Xymelin

Nazivin

Galazolin

Lazorin

Nazivin Sensitive for children

Otrivin

Naphthyzin

Sanorin

Knoxprey

For the nose

Lazolvan Rino

Afrin

Rhinorus

Eucazoline Aqua

Rinazolin

Grippostad Reno

Farmazolin

Xylometazoline

Nazol Advance

Among the main analogues of Rinonorm are:

• Galazolin;
• Nose Spray;
• Brizolin;
• Theiss Nazolin;
• NOS asterisk;
• Xylene;
• Xylometazoline;
• Influrin;
• Xymelin;
• Nosolin;
• Olint;
• Rinomaris;
• Otrivin;
• Rhinorus;
• Snoop;
• Rhinostop;
• Eucazoline Aqua;
• Sanorin-Xylo;
• Tizin Xylo;
• Espazolin;
• Suprima-NOZ;
• Farmazolin.